ATE140795T1 - Homobifunktionelle agenzien zur kupplung von enzymen un deren analogen an antikörper und deren analoge - Google Patents

Homobifunktionelle agenzien zur kupplung von enzymen un deren analogen an antikörper und deren analoge

Info

Publication number
ATE140795T1
ATE140795T1 AT91920049T AT91920049T ATE140795T1 AT E140795 T1 ATE140795 T1 AT E140795T1 AT 91920049 T AT91920049 T AT 91920049T AT 91920049 T AT91920049 T AT 91920049T AT E140795 T1 ATE140795 T1 AT E140795T1
Authority
AT
Austria
Prior art keywords
intrinsic factor
group
disclosed
solution
purified
Prior art date
Application number
AT91920049T
Other languages
English (en)
Inventor
Christopher Bieniarz
Christopher Welch
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE140795T1 publication Critical patent/ATE140795T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT91920049T 1990-10-22 1991-10-18 Homobifunktionelle agenzien zur kupplung von enzymen un deren analogen an antikörper und deren analoge ATE140795T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60079590A 1990-10-22 1990-10-22

Publications (1)

Publication Number Publication Date
ATE140795T1 true ATE140795T1 (de) 1996-08-15

Family

ID=24405079

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91920049T ATE140795T1 (de) 1990-10-22 1991-10-18 Homobifunktionelle agenzien zur kupplung von enzymen un deren analogen an antikörper und deren analoge

Country Status (12)

Country Link
US (1) US5380873A (de)
EP (1) EP0555336B1 (de)
JP (2) JP3360174B2 (de)
KR (1) KR930702683A (de)
AT (1) ATE140795T1 (de)
AU (1) AU657284B2 (de)
CA (1) CA2094397C (de)
DE (1) DE69121108T2 (de)
DK (1) DK0555336T3 (de)
ES (1) ES2092579T3 (de)
GR (1) GR3021097T3 (de)
WO (1) WO1992007268A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2157767A1 (en) * 1993-03-09 1994-09-15 Elaine M. Brate Genetically engineered enzymes and their conjugates for diagnostic assays
US5548064A (en) * 1993-05-24 1996-08-20 Biotech Australia Pty Limited Vitamin B12 conjugates with EPO, analogues thereof and pharmaceutical compositions
US6306665B1 (en) * 1999-10-13 2001-10-23 A-Fem Medical Corporation Covalent bonding of molecules to an activated solid phase material
US7193065B2 (en) * 2001-07-13 2007-03-20 Roche Diagnostics Operations, Inc. Protease inhibitor conjugates and antibodies useful in immunoassay
CA2609702C (en) 2005-04-28 2013-05-28 Ventana Medical Systems, Inc. Antibody conjugates via heterobifunctional peg linkers
JP4793714B2 (ja) * 2005-05-19 2011-10-12 独立行政法人産業技術総合研究所 新規クロスリンカー化合物
DK2963011T3 (en) 2005-11-23 2018-08-06 Ventana Med Syst Inc MOLECULAR CONJUGATE
WO2008136769A1 (en) * 2007-05-03 2008-11-13 Nanyang Technological University Online contaminant detection and removal system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340387C (en) * 1987-10-30 1999-02-09 Carol A. Schlesinger Heterobifunctional coupling agents
US5066490A (en) * 1988-06-01 1991-11-19 The United States Of America As Represented By The Secretary Of The Department Of Health & Human Services Protein crosslinking reagents cleavable within acidified intracellular vesicles
US5104815A (en) * 1988-10-11 1992-04-14 Abbott Laboratories Assay for cobalamins
DK0386644T3 (da) * 1989-03-10 1997-10-13 Hoffmann La Roche Reagenser til bestemmelse af lægemidler

Also Published As

Publication number Publication date
JP3360174B2 (ja) 2002-12-24
DK0555336T3 (da) 1996-11-25
AU8905991A (en) 1992-05-20
AU657284B2 (en) 1995-03-09
JPH06502411A (ja) 1994-03-17
WO1992007268A1 (en) 1992-04-30
ES2092579T3 (es) 1996-12-01
JP2000229926A (ja) 2000-08-22
US5380873A (en) 1995-01-10
CA2094397C (en) 2005-10-04
EP0555336A4 (de) 1994-10-12
KR930702683A (ko) 1993-09-09
GR3021097T3 (en) 1996-12-31
DE69121108D1 (de) 1996-08-29
EP0555336A1 (de) 1993-08-18
CA2094397A1 (en) 1992-04-23
JP3488670B2 (ja) 2004-01-19
DE69121108T2 (de) 1997-02-27
EP0555336B1 (de) 1996-07-24

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