ATE276274T1 - Konjugate von alpha-msh mit einer fettsäure, verfahren zu ihrer herstellung und ihre verwendung als medikament - Google Patents

Konjugate von alpha-msh mit einer fettsäure, verfahren zu ihrer herstellung und ihre verwendung als medikament

Info

Publication number
ATE276274T1
ATE276274T1 AT96922103T AT96922103T ATE276274T1 AT E276274 T1 ATE276274 T1 AT E276274T1 AT 96922103 T AT96922103 T AT 96922103T AT 96922103 T AT96922103 T AT 96922103T AT E276274 T1 ATE276274 T1 AT E276274T1
Authority
AT
Austria
Prior art keywords
alpha
msh
sequence
amino
acids
Prior art date
Application number
AT96922103T
Other languages
English (en)
Inventor
D Hinterland Lucien Dussourd
Anne-Marie Pinel
Original Assignee
Inst Europeen Biolog Cellulair
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Europeen Biolog Cellulair filed Critical Inst Europeen Biolog Cellulair
Application granted granted Critical
Publication of ATE276274T1 publication Critical patent/ATE276274T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/68—Melanocyte-stimulating hormone [MSH]
    • C07K14/685—Alpha-melanotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Fats And Perfumes (AREA)
AT96922103T 1995-06-12 1996-06-12 Konjugate von alpha-msh mit einer fettsäure, verfahren zu ihrer herstellung und ihre verwendung als medikament ATE276274T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9506909A FR2735131B1 (fr) 1995-06-12 1995-06-12 Conjugues d'msh avec un acide gras, leur procede de preparation et leur utilisation a titre de medicament
PCT/FR1996/000890 WO1996041815A2 (fr) 1995-06-12 1996-06-12 CONJUGUES D'αMSH AVEC UN ACIDE GRAS, LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION A TITRE DE MEDICAMENT

Publications (1)

Publication Number Publication Date
ATE276274T1 true ATE276274T1 (de) 2004-10-15

Family

ID=9479857

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96922103T ATE276274T1 (de) 1995-06-12 1996-06-12 Konjugate von alpha-msh mit einer fettsäure, verfahren zu ihrer herstellung und ihre verwendung als medikament

Country Status (8)

Country Link
EP (1) EP0837881B1 (de)
JP (1) JPH11507661A (de)
AT (1) ATE276274T1 (de)
AU (1) AU6309496A (de)
DE (1) DE69633391T2 (de)
ES (1) ES2227597T3 (de)
FR (1) FR2735131B1 (de)
WO (1) WO1996041815A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6579968B1 (en) * 1999-06-29 2003-06-17 Palatin Technologies, Inc. Compositions and methods for treatment of sexual dysfunction
US7176279B2 (en) 2000-06-28 2007-02-13 Palatin Technologies, Inc. Cyclic peptide compositions and methods for treatment of sexual dysfunction
EP1593384A3 (de) * 1999-06-29 2006-04-26 Palatin Technologies, Inc. Verbindungen zur Behandlung von sexuellen Funktionsstörungen
GB9930026D0 (en) * 1999-12-21 2000-02-09 Univ Sheffield Novel compounds of unsaturated fatty acids
US7148197B2 (en) * 2000-08-24 2006-12-12 The Regents Of The University Of California Orally administered small peptides synergize statin activity
US7144862B2 (en) 2000-08-24 2006-12-05 The Regents Of The University Of California Orally administered peptides to ameliorate atherosclerosis
US7199102B2 (en) 2000-08-24 2007-04-03 The Regents Of The University Of California Orally administered peptides synergize statin activity
US7166578B2 (en) 2000-08-24 2007-01-23 The Regents Of The University Of California Orally administered peptides synergize statin activity
JP2004528089A (ja) * 2001-04-17 2004-09-16 ユニバーシティ・オブ・シェフィールド メラニン細胞刺激ホルモン（ｍｓｈ）を含む生体適合材料および形成方法
US8119839B2 (en) 2007-07-20 2012-02-21 Yamada Apiculture Center, Inc. Carboxylic acid and antidepressant composition containing the same as active ingredient
JP5715104B2 (ja) * 2012-09-27 2015-05-07 アブビー インコーポレイティド 治療的に活性なα−ＭＳＨアナログ
US10588980B2 (en) 2014-06-23 2020-03-17 Novartis Ag Fatty acids and their use in conjugation to biomolecules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0389950A1 (de) * 1989-03-23 1990-10-03 Lion Corporation Inhibitor des melanocytenstimulierenden Hormons und dieses enthaltendes, äusserlich anwendbares Präparat
CA2070061C (en) * 1991-06-07 2004-02-10 Shigeyuki Takama Physiologically active polypeptide-containing pharmaceutical composition
FR2691465B1 (fr) * 1992-05-25 1995-08-11 Pf Medicament Complexes comprenant au moins un peptide derive de l'alpha msh, peptide, microsphere, medicament et composition galenique les comprenant.
FR2710340B1 (fr) * 1993-09-22 1995-12-15 D Hinterland Lucien Dussourd Dérivés peptidiques de l'alpha-MSH et leur application .

Also Published As

Publication number Publication date
WO1996041815A3 (fr) 1997-01-30
DE69633391T2 (de) 2005-02-24
JPH11507661A (ja) 1999-07-06
FR2735131B1 (fr) 1997-08-22
FR2735131A1 (fr) 1996-12-13
EP0837881B1 (de) 2004-09-15
DE69633391D1 (de) 2004-10-21
ES2227597T3 (es) 2005-04-01
WO1996041815A2 (fr) 1996-12-27
AU6309496A (en) 1997-01-09
EP0837881A2 (de) 1998-04-29

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties