ATE134629T1 - Thioharnstoffderivate und sie enthaltendes, antimikrobielles und antiulcerogenes mittel - Google Patents
Thioharnstoffderivate und sie enthaltendes, antimikrobielles und antiulcerogenes mittelInfo
- Publication number
- ATE134629T1 ATE134629T1 AT92402434T AT92402434T ATE134629T1 AT E134629 T1 ATE134629 T1 AT E134629T1 AT 92402434 T AT92402434 T AT 92402434T AT 92402434 T AT92402434 T AT 92402434T AT E134629 T1 ATE134629 T1 AT E134629T1
- Authority
- AT
- Austria
- Prior art keywords
- antimicrobial
- thiourea derivatives
- antiulcerogenic
- integer
- formula
- Prior art date
Links
- 230000000845 anti-microbial effect Effects 0.000 title abstract 2
- 230000000026 anti-ulcerogenic effect Effects 0.000 title 1
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical class NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 title 1
- 241000589989 Helicobacter Species 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000003585 thioureas Chemical class 0.000 abstract 2
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Curing Cements, Concrete, And Artificial Stone (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Disintegrating Or Milling (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3227466A JPH0559038A (ja) | 1991-09-06 | 1991-09-06 | チオウレア誘導体及びこれを含有する医薬製剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE134629T1 true ATE134629T1 (de) | 1996-03-15 |
Family
ID=16861320
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92402434T ATE134629T1 (de) | 1991-09-06 | 1992-09-04 | Thioharnstoffderivate und sie enthaltendes, antimikrobielles und antiulcerogenes mittel |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5214053A (de) |
| EP (1) | EP0531228B1 (de) |
| JP (1) | JPH0559038A (de) |
| KR (1) | KR950001040B1 (de) |
| CN (1) | CN1032650C (de) |
| AT (1) | ATE134629T1 (de) |
| AU (1) | AU634933B1 (de) |
| CA (1) | CA2077122A1 (de) |
| DE (1) | DE69208569T2 (de) |
| ID (1) | ID821B (de) |
| RU (1) | RU2056416C1 (de) |
| TW (1) | TW202440B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7141244B1 (en) * | 1992-03-02 | 2006-11-28 | Chiron Srl | Helicobacter pylori proteins useful for vaccines and diagnostics |
| ES2111625T3 (es) * | 1992-07-06 | 1998-03-16 | Nestle Sa | Agente antigastritis. |
| WO1995001337A1 (en) * | 1993-06-30 | 1995-01-12 | Sankyo Company, Limited | Thiourea derivative |
| ATE229978T1 (de) * | 1994-07-01 | 2003-01-15 | Chiron Corp | Helicobacter proteine und impstoffe |
| DK0909323T3 (da) * | 1996-01-04 | 2007-05-21 | Novartis Vaccines & Diagnostic | Helicobacter pylori-bakterioferritin |
| US6190667B1 (en) * | 1998-06-30 | 2001-02-20 | Institut Pasteur | Methods of inhibiting Helicobacter pylori |
| RU2145975C1 (ru) * | 1999-07-19 | 2000-02-27 | Тверская медакадемия | Способ культивирования helicobacter pylori |
| CN1101459C (zh) * | 2000-03-31 | 2003-02-12 | 北京燕山石油化工公司研究院 | 冷冻机用润滑油 |
| DE60218031T2 (de) * | 2001-05-15 | 2007-11-08 | Matsushita Electric Industrial Co., Ltd., Kadoma | SCHMIERMITTELZUSAMMENSETZUNG für Spindelmotor |
| US20050175629A1 (en) * | 2001-08-31 | 2005-08-11 | Giuseppe Del Giudice | Helicobacter pylori vaccination |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3950537A (en) * | 1973-06-29 | 1976-04-13 | Rohm And Haas Company | Gastrointestinally active thioureas |
| AU7235287A (en) * | 1986-03-28 | 1987-10-20 | Janus Farmaceutici S.R.L | Synthesis of antiulcer compounds |
| JPH04364160A (ja) * | 1990-08-03 | 1992-12-16 | Terumo Corp | チオウレア誘導体およびこれを含有する抗菌剤および抗潰瘍剤 |
-
1991
- 1991-09-06 JP JP3227466A patent/JPH0559038A/ja active Pending
-
1992
- 1992-08-04 ID IDP466992A patent/ID821B/id unknown
- 1992-08-28 CA CA002077122A patent/CA2077122A1/en not_active Abandoned
- 1992-09-02 AU AU22063/92A patent/AU634933B1/en not_active Ceased
- 1992-09-02 US US07/939,692 patent/US5214053A/en not_active Expired - Fee Related
- 1992-09-04 RU SU925052910A patent/RU2056416C1/ru active
- 1992-09-04 KR KR1019920016158A patent/KR950001040B1/ko not_active Expired - Fee Related
- 1992-09-04 DE DE69208569T patent/DE69208569T2/de not_active Expired - Fee Related
- 1992-09-04 AT AT92402434T patent/ATE134629T1/de not_active IP Right Cessation
- 1992-09-04 EP EP92402434A patent/EP0531228B1/de not_active Expired - Lifetime
- 1992-09-05 TW TW081107050A patent/TW202440B/zh active
- 1992-09-05 CN CN92111220A patent/CN1032650C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ID821B (id) | 1996-07-22 |
| RU2056416C1 (ru) | 1996-03-20 |
| KR950001040B1 (ko) | 1995-02-08 |
| JPH0559038A (ja) | 1993-03-09 |
| CA2077122A1 (en) | 1993-03-07 |
| TW202440B (de) | 1993-03-21 |
| AU634933B1 (en) | 1993-03-04 |
| KR930005999A (ko) | 1993-04-20 |
| DE69208569D1 (de) | 1996-04-04 |
| CN1032650C (zh) | 1996-08-28 |
| US5214053A (en) | 1993-05-25 |
| EP0531228B1 (de) | 1996-02-28 |
| CN1070909A (zh) | 1993-04-14 |
| EP0531228A1 (de) | 1993-03-10 |
| DE69208569T2 (de) | 1996-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |