ATE129148T1 - Zusammensetzungen und verfahren zur herstellung von im mund zersetzlichen heilmitteln. - Google Patents

Zusammensetzungen und verfahren zur herstellung von im mund zersetzlichen heilmitteln.

Info

Publication number
ATE129148T1
ATE129148T1 AT90912733T AT90912733T ATE129148T1 AT E129148 T1 ATE129148 T1 AT E129148T1 AT 90912733 T AT90912733 T AT 90912733T AT 90912733 T AT90912733 T AT 90912733T AT E129148 T1 ATE129148 T1 AT E129148T1
Authority
AT
Austria
Prior art keywords
remedies
degradable
oral
compositions
production
Prior art date
Application number
AT90912733T
Other languages
English (en)
Inventor
Theodore H Stanley
Brian Hague
Original Assignee
Univ Utah Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utah Res Found filed Critical Univ Utah Res Found
Application granted granted Critical
Publication of ATE129148T1 publication Critical patent/ATE129148T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/368Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/50Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
    • A23G3/54Composite products, e.g. layered, coated, filled
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/50Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
    • A23G3/56Products with edible or inedible supports, e.g. lollipops
    • A23G3/563Products with edible or inedible supports, e.g. lollipops products with an inedible support, e.g. a stick
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/0015Devices specially adapted for taking medicines
    • A61J7/003Sticks, e.g. lollipops with drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT90912733T 1989-09-05 1990-08-03 Zusammensetzungen und verfahren zur herstellung von im mund zersetzlichen heilmitteln. ATE129148T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/403,751 US5288497A (en) 1985-05-01 1989-09-05 Compositions of oral dissolvable medicaments

Publications (1)

Publication Number Publication Date
ATE129148T1 true ATE129148T1 (de) 1995-11-15

Family

ID=23596872

Family Applications (2)

Application Number Title Priority Date Filing Date
AT90912733T ATE129148T1 (de) 1989-09-05 1990-08-03 Zusammensetzungen und verfahren zur herstellung von im mund zersetzlichen heilmitteln.
AT94111352T ATE177007T1 (de) 1989-09-05 1990-08-03 Zusammensetzungen und verfahren zur herstellung von im mund zersetzlichen heilmitteln

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT94111352T ATE177007T1 (de) 1989-09-05 1990-08-03 Zusammensetzungen und verfahren zur herstellung von im mund zersetzlichen heilmitteln

Country Status (11)

Country Link
US (1) US5288497A (de)
EP (2) EP0490916B1 (de)
JP (1) JP2717024B2 (de)
AT (2) ATE129148T1 (de)
AU (2) AU645265B2 (de)
CA (1) CA2066423C (de)
DE (2) DE69023143T2 (de)
DK (2) DK0490916T3 (de)
ES (2) ES2133448T3 (de)
NO (1) NO304348B1 (de)
WO (1) WO1991003237A1 (de)

Families Citing this family (181)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
US5824334A (en) * 1989-09-05 1998-10-20 University Of Utah Research Foundation Tobacco substitute
IT1238072B (it) * 1990-01-19 1993-07-03 Sclavo Spa Composizioni farmaceutiche e forme di dosaggio per la somministrazione orale di calcitonina
US5223259A (en) * 1990-09-19 1993-06-29 Lackney Albert M Securing means for an oral medicament and support therefor
DE69212497T2 (de) * 1991-12-05 1996-12-12 Mallinckrodt Veterinary Inc Glasartige kohlenhydratenmatrize zur verabreichung von heilmitteln mit verzögerter wirkstoffabgabe
HU219349B (en) * 1991-12-24 2001-03-28 Yamanouchi Pharma Co Ltd Intrabuccally disintegrating preparation and production thereof
GB9212511D0 (en) * 1992-06-12 1992-07-22 Cortecs Ltd Pharmaceutical compositions
GB9213874D0 (en) * 1992-06-30 1992-08-12 Fisons Plc Process to novel medicament form
JPH0776527A (ja) * 1993-06-28 1995-03-20 Hayashibara Biochem Lab Inc 半固形製剤とその製造方法
US5549906A (en) * 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
WO1995003771A1 (en) * 1993-08-03 1995-02-09 Pacific Rim Productions Pty. Ltd. Treatment of oral ailments
US6352713B1 (en) 1999-12-01 2002-03-05 Drugtech Corporation Nutritional composition
US6488956B1 (en) * 1994-06-20 2002-12-03 Drugtech Corporation Multi-vitamin and mineral supplements for women
MA23587A1 (fr) * 1994-06-23 1995-12-31 Procter & Gamble Traitement du besoin en nicotine et/ou du syndrome de manque lie au tabagisme
WO1996000072A1 (en) * 1994-06-23 1996-01-04 The Procter & Gamble Company Treatment of nicotine craving and/or smoking withdrawal symptoms with a transdermal or transmucosal composition containing nicotine and caffeine or xanthine
AU2702795A (en) * 1994-06-23 1996-01-19 Procter & Gamble Company, The Treatment of nicotine craving and/or smoking withdrawal symptoms with a solid or semi-solid composition containing nicotine and caffeine or xanthine, especially for nasal administration
GB2325409B (en) * 1994-06-28 1999-02-10 Kenneth Francis Prendergast Pharmaceutical use of ondansetron/cyclodextrin complexes
GB9423511D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
EP0808629A4 (de) * 1995-02-02 1998-03-04 Chugai Pharmaceutical Co Ltd Zubereitung von sucralfat
US5788982A (en) * 1995-06-16 1998-08-04 Nadoolman; Wolffe Method and composition for treating oral pain using capsaicin
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
US5912014A (en) * 1996-03-15 1999-06-15 Unigene Laboratories, Inc. Oral salmon calcitonin pharmaceutical products
SE9601421D0 (sv) * 1996-04-12 1996-04-12 Astra Ab New composition
BR9709452B1 (pt) 1996-05-13 2008-11-18 sistema de liberaÇço bucal na forma de uma pastilha degastÁvel.
US5726154A (en) * 1996-06-28 1998-03-10 University Of Utah Research Foundation Stabilization and oral delivery of calcitonin
EP1024833A1 (de) * 1996-07-11 2000-08-09 Farmarc Nederland B.V. Pharmazeutische zusammensetzung mit saurem zusatzsalz der basischen droge
DE19646392A1 (de) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
GB9706089D0 (en) * 1997-03-24 1997-05-14 Scherer Ltd R P Pharmaceutical composition
US20040023948A1 (en) * 1997-03-24 2004-02-05 Green Richard David Fast-dispersing dosage form containing 5-HT1 agonists
TW586934B (en) * 1997-05-19 2004-05-11 Sumitomo Pharma Immunopotentiating composition
US6197331B1 (en) 1997-07-24 2001-03-06 Perio Products Ltd. Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity
US6177282B1 (en) * 1997-08-12 2001-01-23 Mcintyre John A. Antigens embedded in thermoplastic
GB9717770D0 (en) * 1997-08-21 1997-10-29 Scherer Ltd R P Pharmaceutical composition
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6074674A (en) * 1997-10-31 2000-06-13 University Of Kentucky Research Foundation Formulations for sustained-release of topical anesthetics and methods of making and using same
US7070799B1 (en) * 1998-02-10 2006-07-04 Generex Pharmaceuticals, Inc. Method for administering insulin to the buccal region
US6221378B1 (en) 1998-02-10 2001-04-24 Generex Pharmaceuticals Incorporated Mixed micellar delivery system and method of preparation
US5997884A (en) * 1998-02-12 1999-12-07 Taylor Pharmaceuticals Compositions and method for treating migraine
US5981552A (en) * 1998-10-23 1999-11-09 Taylor Pharmaceuticals Sublingual and buccal compositions of droperidol and method for treating migraine
US5990134A (en) * 1998-08-12 1999-11-23 Taylor Pharmaceuticals Oral droperidol compositions and method for treating migraine
US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US6103257A (en) * 1998-07-17 2000-08-15 Num-Pop, Inc. System for delivering pharmaceuticals to the buccal mucosa
US6368625B1 (en) 1998-08-12 2002-04-09 Cima Labs Inc. Orally disintegrable tablet forming a viscous slurry
IL141095A0 (en) * 1998-08-19 2002-02-10 Rtp Pharma Inc Injectable aqueous dispersions of propofol
US6358060B2 (en) * 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
US6344222B1 (en) 1998-09-03 2002-02-05 Jsr Llc Medicated chewing gum delivery system for nicotine
SE9803239D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain
SE9803240D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
US6294153B1 (en) 1998-12-21 2001-09-25 Generex Pharmaceuticals, Inc. Aerosol pharmaceutical formulation for pulmonary and nasal delivery
MXPA01007024A (es) 1999-01-08 2002-03-27 B Bacaner Marvin Composiciones y equipos novedosos de bretilio y su uso en la prevencion y el tratamiento de condiciones cardiovasculares.
US6242473B1 (en) 1999-01-08 2001-06-05 Maxim Pharmaceuticals, Inc. Treatment and prevention of reactive oxygen metabolite-mediated cellular damage
US6270781B1 (en) 1999-01-08 2001-08-07 Maxim Pharmaceuticals, Inc. Method and compositions for topical treatment of damaged tissue using reactive oxygen metabolite production or release inhibitors
US6884792B2 (en) * 1999-01-08 2005-04-26 Marvin B. Bacaner Bretylium compositions and kits and their use in preventing and treating cardiovascular conditions
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
US20070148228A1 (en) * 1999-02-22 2007-06-28 Merrion Research I Limited Solid oral dosage form containing an enhancer
US7658938B2 (en) 1999-02-22 2010-02-09 Merrion Reasearch III Limited Solid oral dosage form containing an enhancer
US8119159B2 (en) * 1999-02-22 2012-02-21 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
US6350432B1 (en) 1999-03-19 2002-02-26 Generex Pharmaceuticals Incorporated Pressurized container having an aerosolized pharmaceutical composition
US6248760B1 (en) * 1999-04-14 2001-06-19 Paul C Wilhelmsen Tablet giving rapid release of nicotine for transmucosal administration
JP2003501488A (ja) * 1999-06-11 2003-01-14 ネオルックス コーポレイション 骨髄抑制のための高投与量放射性核種錯体
DE19932603A1 (de) * 1999-07-13 2001-01-25 Gruenenthal Gmbh Wirkstoffhaltiger Mehrschichtfilm aus in situ vernetzten hydrophilen Polymeren
AU6528400A (en) 1999-08-23 2001-03-19 David M. Ockert Triple drug therapy for the treatment of narcotic and alcohol withdrawal symptoms
WO2001051089A1 (de) * 2000-01-13 2001-07-19 Merck Patent Gmbh Pharmazeutische zubereitungen enthaltend 2-pyrrolidon als lösungsvermittler
WO2001089476A1 (en) * 2000-05-19 2001-11-29 Npd Llc Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements
US6526993B1 (en) * 2000-09-12 2003-03-04 Eugene C. Wagner Dental implement with comfit grip
US6365215B1 (en) * 2000-11-09 2002-04-02 International Flavors & Fragrances Inc. Oral sensory perception-affecting compositions containing dimethyl sulfoxide, complexes thereof and salts thereof
US20020106407A1 (en) * 2000-12-11 2002-08-08 Dennis Coleman Method and apparatus for treating breakthrough pain
US20020160043A1 (en) * 2001-02-27 2002-10-31 Dennis Coleman Compositions and method of manufacture for oral dissolvable dosage forms
US20030118628A1 (en) * 2001-04-05 2003-06-26 Tutuncu Nurhan Pinar Confectionery product having a salivation region and an oral comfort region
WO2002092616A1 (en) * 2001-05-11 2002-11-21 Orasense, Ltd. Antisense permeation enhancers
US20030153590A1 (en) * 2001-08-14 2003-08-14 Oy Contral Pharma Ltd Method of treating alcoholism or alcohol abuse
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US20030049304A1 (en) * 2001-08-29 2003-03-13 Somani Jitendra Krishan Quiescently frozen ice products
US20030091553A1 (en) * 2001-10-19 2003-05-15 Gehlsen Kurt R. Use of histamine to treat liver disease
CA2466083A1 (en) * 2001-11-06 2003-05-15 Maxim Pharmaceuticals, Inc. Compositions for the treatment of infectious diseases
GB0210397D0 (en) * 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
US20040097467A1 (en) * 2002-08-22 2004-05-20 Vijaya Juturu Arginine silicate inositol complex and use thereof
US6592908B1 (en) 2002-09-23 2003-07-15 Albert Crum Nutritional or therapeutic compositions
US20040115244A1 (en) * 2002-12-17 2004-06-17 Holgate Eric Jamison Methods and compositions for nicotine replacement therapy
US8088734B2 (en) * 2003-01-21 2012-01-03 Unigene Laboratories Inc. Oral delivery of peptides
US20080213363A1 (en) * 2003-01-23 2008-09-04 Singh Nikhilesh N Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa
US20040253307A1 (en) * 2003-02-04 2004-12-16 Brian Hague Sugar-free oral transmucosal solid dosage forms and uses thereof
US20060062812A1 (en) * 2003-03-11 2006-03-23 Calvin Ross Novel compositions
US6966252B2 (en) 2003-03-31 2005-11-22 Mcneil-Ppc, Inc. Hydrophilic substance dispensing device
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
BRPI0302736B8 (pt) 2003-06-02 2021-05-25 Ems S/A composição farmacêutica a base de cetorolaco ou de um de seus sais farmaceuticamente aceitáveis para uso sublingual
EP1648362A4 (de) * 2003-07-01 2012-01-11 Todd Maibach Therapeutische mittel mit film
WO2005018565A2 (en) * 2003-08-21 2005-03-03 Transoral Pharmaceuticals, Inc. Compositions for delivering 5-ht agonists across the oral mucosa and methods of use thereof
US20050042281A1 (en) * 2003-08-21 2005-02-24 Singh Nikhilesh N. Compositions for delivering therapeutic agents across the oral mucosa
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
US8627828B2 (en) * 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
CN102669810B (zh) 2003-11-07 2014-11-05 美国无烟烟草有限责任公司 烟草组合物
US20050171192A1 (en) * 2003-12-11 2005-08-04 Gehlsen Kurt R. Use of histamine to treat bone disease
JP5244318B2 (ja) * 2003-12-31 2013-07-24 シーマ・ラブス、インコーポレイテッド 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法
US7858121B2 (en) * 2003-12-31 2010-12-28 Cima Labs, Inc. Effervescent oral fentanyl dosage form and methods of administering fentanyl
KR101184138B1 (ko) * 2003-12-31 2012-09-19 시마 랩스 인크. 일반적인 선형 발포성 경구 펜타닐 투약 제형 및 투여 방법
US7658945B2 (en) * 2004-02-17 2010-02-09 Transcept Pharmaceuticals, Inc. Compositions for delivering hypnotic agents across the oral mucosa and methods of use thereof
US20060002913A1 (en) * 2004-06-22 2006-01-05 Gehlsen Kurt R Use of histamine and related compounds to treat disorders affecting muscle function
US20060004035A1 (en) * 2004-06-25 2006-01-05 Cephalon, Inc. System for identification of a pharmaceutical product
US20060029665A1 (en) * 2004-08-03 2006-02-09 Transoral Pharmaceuticals, Inc. Pilocarpine compositions and methods of use thereof
WO2006073514A2 (en) * 2004-08-25 2006-07-13 Tufts University Compositions, methods and kits for repressing virulence in gram positive bacteria
US20060051413A1 (en) * 2004-09-08 2006-03-09 Chow Sing S M Method of enhancing absorptions of transmucosal administration formulations
US20050196517A1 (en) * 2005-02-14 2005-09-08 Mars, Incorporated Edible product having discrete regions with different heats of solution
US20070287740A1 (en) * 2005-05-25 2007-12-13 Transcept Pharmaceuticals, Inc. Compositions and methods of treating middle-of-the night insomnia
AU2006249761A1 (en) * 2005-05-25 2006-11-30 Transcept Pharmaceuticals, Inc. Solid compositions and methods for treating middle-of-the night insomnia
US20070225322A1 (en) * 2005-05-25 2007-09-27 Transoral Pharmaceuticals, Inc. Compositions and methods for treating middle-of-the night insomnia
US20070104763A1 (en) * 2005-11-10 2007-05-10 Navinta Llc Composition of fentanyl citrate oral solid transmucosal dosage form, excipient and binding material therefore, and methods of making
US8679545B2 (en) * 2005-11-12 2014-03-25 The Regents Of The University Of California Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US8324192B2 (en) 2005-11-12 2012-12-04 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
US9289583B2 (en) * 2006-01-06 2016-03-22 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8252328B2 (en) * 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US9066847B2 (en) * 2007-01-05 2015-06-30 Aceirx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8753308B2 (en) 2006-01-06 2014-06-17 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8357114B2 (en) 2006-01-06 2013-01-22 Acelrx Pharmaceuticals, Inc. Drug dispensing device with flexible push rod
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
EP2007397B1 (de) * 2006-04-07 2013-07-24 Merrion Research III Limited Feste orale Darreichungsform mit einem Verstärker
US20070260491A1 (en) * 2006-05-08 2007-11-08 Pamela Palmer System for delivery and monitoring of administration of controlled substances
WO2007143675A2 (en) * 2006-06-05 2007-12-13 Verus Pharmaceuticals, Inc. Methods for buccal, lingual or sublingual dosing regimens of epinephrine for the treatment of allergic emergencies
EP2040731A4 (de) * 2006-06-09 2010-05-19 Merrion Res Iii Ltd Feste orale dosierform mit einem verstärkungsmittel
US20070299687A1 (en) * 2006-06-23 2007-12-27 Pamela Palmer Inpatient system for patient-controlled delivery of oral transmucosal medications dosed as needed
US8642016B2 (en) * 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
EP3067044B1 (de) 2006-07-21 2019-03-27 BioDelivery Sciences International, Inc. Vorrichtungen zur transmukosalen abgabe mit verbesserter aufnahme
US8158609B1 (en) 2006-11-02 2012-04-17 Novartis Ag Use of cyclodextrins as an active ingredient for treating dry AMD and solubilizing drusen
US20090214442A1 (en) * 2006-12-01 2009-08-27 Cephalon, Inc. Oral Transmucosal Nicotine Dosage Form
US20080131508A1 (en) * 2006-12-01 2008-06-05 Cephalon, Inc Oral transmucosal nicotine dosage form
EP1938756A1 (de) * 2006-12-29 2008-07-02 Qiagen GmbH Verfahren und Materialen zur gesteuerten Freisetzung einer biologischen Probe
US20100028447A1 (en) 2007-01-22 2010-02-04 Targacept, Inc. Intranasal, Buccal, And Sublingual Administration Of Metanicotine Analogs
WO2008098195A2 (en) * 2007-02-09 2008-08-14 Todd Maibach Film comprising nitroglycerin
CA2677281C (en) * 2007-02-09 2019-10-29 Durect Corporation Transoral dosage forms comprising sufentanil and naloxone
JP2010529142A (ja) * 2007-06-08 2010-08-26 アドレネクス・ファーマシューティカルズ,インコーポレイテッド アドレナリン調節異常症を治療する徐放性の製剤および方法
US20100172991A1 (en) * 2007-06-08 2010-07-08 Henry Joseph Horacek Extended Release Formulation and Methods of Treating Adrenergic Dysregulation
US20090004254A1 (en) * 2007-06-19 2009-01-01 Todd Maibach Film comprising active drugs
EP2025332A1 (de) * 2007-08-13 2009-02-18 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Auf Ton basierende aromatisierte therapeutische Zusammensetzung
US20090123551A1 (en) * 2007-11-13 2009-05-14 Meritage Pharma, Inc. Gastrointestinal delivery systems
US20100216754A1 (en) * 2007-11-13 2010-08-26 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
SI3354276T1 (sl) 2007-11-13 2020-09-30 Meritage Pharma, Inc. Sestavki za zdravljenje gastrointestinalnega vnetja
US20090143343A1 (en) * 2007-11-13 2009-06-04 Meritage Pharma, Inc. Compositions for the treatment of inflammation of the gastrointestinal tract
US20090264392A1 (en) * 2008-04-21 2009-10-22 Meritage Pharma, Inc. Treating eosinophilic esophagitis
US8999383B2 (en) * 2008-05-07 2015-04-07 Merrion Research Iii Limited Compositions of GnRH related compounds and processes of preparation
BRPI0822655A2 (pt) * 2008-06-04 2015-06-30 Colgate Palmolive Co Implemento e sistema para cuidado oral
US20100055050A1 (en) * 2008-08-30 2010-03-04 Kathleen Moore Nicotine chewing gum on a stick
US8945592B2 (en) 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
WO2010077878A1 (en) * 2008-12-15 2010-07-08 Fleming And Company, Pharmaceuticals Rapidly dissolving vitamin formulation and methods of using the same
TWI480286B (zh) * 2009-02-25 2015-04-11 Merrion Res Iii Ltd 雙膦酸鹽類組合物及藥物遞送
WO2010144865A2 (en) * 2009-06-12 2010-12-16 Meritage Pharma, Inc. Methods for treating gastrointestinal disorders
PL4104848T3 (pl) 2009-06-18 2024-03-25 Acerus Pharmaceuticals USA, LLC Bezpieczne podawanie desmopresyny
US8475832B2 (en) * 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
CA2780294C (en) 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
WO2011057133A1 (en) 2009-11-09 2011-05-12 Spotlight Technology Partners Llc Fragmented hydrogels
US20110182985A1 (en) * 2010-01-28 2011-07-28 Coughlan David C Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof
US9089484B2 (en) * 2010-03-26 2015-07-28 Merrion Research Iii Limited Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
US8623409B1 (en) 2010-10-20 2014-01-07 Tris Pharma Inc. Clonidine formulation
KR20140026354A (ko) 2011-01-07 2014-03-05 메리온 리서치 Ⅲ 리미티드 경구 투여용 철의 제약 조성물
AU2012296346A1 (en) 2011-08-18 2014-04-03 Biodelivery Sciences International, Inc. Abuse-resistant mucoadhesive devices for delivery of buprenorphine
AU2012311293B2 (en) 2011-09-19 2014-02-20 Orexo Ab New abuse-resistant pharmaceutical composition for the treatment of opioid dependence
US9901539B2 (en) 2011-12-21 2018-02-27 Biodelivery Sciences International, Inc. Transmucosal drug delivery devices for use in chronic pain relief
BR112014016085A8 (pt) 2011-12-28 2017-07-04 Pozen Inc composições aprimoradas e métodos para distribuição de omeprazol mais ácido acetilsalicílico
PE20142444A1 (es) 2012-05-02 2015-01-09 Orexo Ab Nueva composicion de alfentanilo para el tratamiento del dolor agudo
US20160051495A1 (en) * 2014-08-20 2016-02-25 Professional Compounding Centers Of America Oral Transmucosal Compositions including C-SERMs for Low Testosterone Levels in Men
US20160051496A1 (en) * 2014-08-20 2016-02-25 Tsu-I Catherine Wang Oral Transmucosal Compositions Including C-SERMs for Treating Female Infertility
CA2958753C (en) 2014-08-29 2021-09-07 Albert B. Crum A method for side effect reduction in the use of statins via physiologically synthesized glutathione
JP7211704B2 (ja) 2015-01-29 2023-01-24 ノヴォ ノルディスク アー/エス Glp-1アゴニスト及び腸溶コーティングを含む錠剤
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9375478B1 (en) 2015-01-30 2016-06-28 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US11191735B2 (en) 2015-03-13 2021-12-07 Nutrition 21, Llc Arginine silicate for periodontal disease
US20170135969A1 (en) 2015-11-12 2017-05-18 Jds Therapeutics, Llc Topical arginine-silicate-inositol for wound healing
EP3506895A4 (de) 2016-09-01 2020-04-15 JDS Therapeutics, LLC Magnesiumbiotinatzusammensetzungen und verfahren zur verwendung
GB201709141D0 (en) 2017-06-08 2017-07-26 Klaria Pharma Holding Ab Pharmaceutical formulation
JP2022515314A (ja) 2018-11-02 2022-02-18 ニュートリション・21,エルエルシー イノシトール安定化アルギニンケイ酸塩複合体及びイノシトールを含有するビデオゲームプレーヤーの認知機能を改善するための組成物
EP4076413A1 (de) 2019-12-16 2022-10-26 Nutrition 21, LLC Verfahren zur herstellung von arginin-silikat-komplexen
US11918689B1 (en) 2020-07-28 2024-03-05 Tris Pharma Inc Liquid clonidine extended release composition

Family Cites Families (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US122507A (en) * 1872-01-02 Improvement in medical compounds or worm-candies
US1971560A (en) * 1928-10-22 1934-08-28 Parker Meyer Dennis Company Candy and holder therefor
US2096611A (en) * 1935-02-07 1937-10-19 Parker Meyer Dennis Company Confection
US2208120A (en) * 1938-03-02 1940-07-16 William B Coleman Pharmaceutical preparation and method of making same
US2246778A (en) * 1939-12-21 1941-06-24 Edward E Cahoon Safety handle for confections
US2295042A (en) * 1941-08-25 1942-09-08 Robert L Llewellyn Fish plug
GB550296A (en) * 1941-11-17 1943-01-01 British Oxygen Co Ltd Improvements in or relating to the administration of inhalant gas mixtures
US2323656A (en) * 1942-07-28 1943-07-06 Helfenstein John Fishhook
US2508560A (en) * 1946-10-22 1950-05-23 Mozel A Adams Fishing lure
GB628709A (en) * 1947-10-06 1949-09-02 William Edmondson An appliance for the production and administration of gas-vapour mixtures
US2488272A (en) * 1948-08-06 1949-11-15 Harry E Davis Cellophane stick and method of making it
US2469589A (en) * 1948-09-20 1949-05-10 Toy Pop Corp Confection with support therefor
GB646680A (en) * 1948-10-27 1950-11-29 William Edmondson Apparatus for mixing the vapour of a volatile anaesthetic with air
US2915061A (en) * 1956-12-24 1959-12-01 Cyprane Ltd Volatile anaesthetic vaporising apparatus
US2926121A (en) * 1957-03-20 1960-02-23 American Home Prod Therapeutic candy-like product and its preparation
US2857908A (en) * 1957-04-26 1958-10-28 Leslie S Cornfield Candy coated tongue depressor
US2897624A (en) * 1958-06-27 1959-08-04 Frederick O Yakel Conservation fishhooks
US2963404A (en) * 1958-09-05 1960-12-06 Pfizer & Co C Tannate candy making, and product
US3210247A (en) * 1960-04-16 1965-10-05 Anti-epileptic i-cyclohexyl-z-methyl- aiviino propane salt of phenyl ethyl barbituric acid
CH410963A (de) * 1960-07-28 1966-04-15 Hommel Ag Verfahren zur Herstellung von 5-Allyl-5-(B-oxypropyl)-barbitursäure
GB968054A (en) * 1962-02-15 1964-08-26 Cyprane Ltd Improvements in volatile anaesthetic vaporising apparatus
US3114642A (en) * 1962-04-20 1963-12-17 Corn Products Co Hard candy and process for making same
US3264115A (en) * 1962-07-10 1966-08-02 Harry E Davis Safety lollipop
US3493652A (en) * 1962-09-14 1970-02-03 Charles W Hartman Controlled release medicament
US3271256A (en) * 1963-03-21 1966-09-06 Richardson Merrell Inc Chloroform in hard candy
US3172179A (en) * 1963-08-12 1965-03-09 John V Schafer Collar fastener
GB1083896A (en) * 1964-04-30 1967-09-20 Dunster Lab Ltd Vehicles for administering drugs
GB1071659A (en) * 1964-06-09 1967-06-07 Cyprane Ltd Improvements in or relating to volatile anaesthetic vaporising apparatus
US3344030A (en) * 1964-06-15 1967-09-26 American Home Prod Reinforced directly compressed nongranulated pharmaceutical crystalline lactose tables
US3341414A (en) * 1964-08-27 1967-09-12 Merck & Co Inc N-cyclohexylsulfamate solubilized medication
GB1171691A (en) * 1967-02-24 1969-11-26 Forest Laboratories Lond-Acting Oral Carrier
US3438787A (en) * 1967-03-09 1969-04-15 Atlas Chem Ind Sugarless confection
US3418743A (en) * 1967-05-02 1968-12-31 Roy H. Halvorsen Fish lure with retractable hooks
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3556811A (en) * 1969-08-11 1971-01-19 Walton J Smith Low-fermentability hard candy
US3697641A (en) * 1970-01-02 1972-10-10 Gerhard W Ahrens Nonhygroscopic non-sugarbase noncariogenic-vitamin c releasable base material for use in the preparation of suckable tablets,lozenges and chocolate
US3622352A (en) * 1970-04-30 1971-11-23 Philip Morris Inc Edible compositions and method for coating them
US3996934A (en) * 1971-08-09 1976-12-14 Alza Corporation Medical bandage
US3738845A (en) * 1972-01-07 1973-06-12 Pfizer Process for the manufacture of sugarless confections
FI50578C (fi) * 1972-09-05 1976-05-10 Haemeen Anttila Yrjoe Sakari Syöksykoukuilla varustettu uistin
US3867927A (en) * 1974-06-13 1975-02-25 Patrick F Hergott Tongue blade sucker
US3943928A (en) * 1974-09-25 1976-03-16 Lariccia Anthony H Eliminating the safety hazard in oral dissolution of a solid
US4093709A (en) * 1975-01-28 1978-06-06 Alza Corporation Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates)
US4131648A (en) * 1975-01-28 1978-12-26 Alza Corporation Structured orthoester and orthocarbonate drug delivery devices
US4168308A (en) * 1976-03-12 1979-09-18 Apoteksvarucentralen Vitrum Ab Composition for enhancing the administration of pharmacologically active agents
US4060084A (en) * 1976-09-07 1977-11-29 Alza Corporation Method and therapeutic system for providing chemotherapy transdermally
DE2712161C2 (de) * 1977-03-19 1983-01-05 Blendax-Werke R. Schneider Gmbh & Co, 6500 Mainz Zahn- und Mundpflegemittel
DD132404B1 (de) * 1977-08-12 1983-04-27 Roland Schubert Verfahren zur herstellung eines arzneimitteltraegers
US4139627A (en) * 1977-10-06 1979-02-13 Beecham Inc. Anesthetic lozenges
DE2860482D1 (en) * 1977-11-07 1981-03-26 Beecham Inc Anaesthetic lozenges and method of preparing them
JPS5562012A (en) * 1978-11-06 1980-05-10 Teijin Ltd Slow-releasing preparation
US4225627A (en) * 1979-01-08 1980-09-30 A. E. Staley Manufacturing Company Demolding confections with steam
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4307075A (en) * 1979-09-13 1981-12-22 American Home Products Corporation Topical treatment of aphthous stomatitis
US4241092A (en) * 1979-10-26 1980-12-23 General Foods Corporation Gasified candy dispersed in a matrix of sorbitol
US4335147A (en) * 1980-03-12 1982-06-15 Helmut Sollich Method for making confections
US4311722A (en) * 1980-07-11 1982-01-19 Life Savers, Inc. High fructose hard candy
JPS5758615A (en) * 1980-09-26 1982-04-08 Nippon Soda Co Ltd Film agnent and its preparation
JPS5843368B2 (ja) * 1980-10-30 1983-09-27 日東電工株式会社 消炎鎮痛貼付剤
US4346709A (en) * 1980-11-10 1982-08-31 Alza Corporation Drug delivery devices comprising erodible polymer and erosion rate modifier
IL61721A (en) * 1980-12-16 1984-03-30 Blank Izhak Nitroglycerin preparations
JPS6059207B2 (ja) * 1981-03-13 1985-12-24 日東電工株式会社 複合製剤の製法
AU8533582A (en) * 1981-07-10 1984-01-12 Reckitt & Colman Products Limited Stable solutions of buprenorphine
SU1011126A1 (ru) * 1981-07-14 1983-04-15 Всесоюзный научно-исследовательский и испытательный институт медицинской техники Средство дл лечени сахарного диабета
US4372942A (en) * 1981-08-13 1983-02-08 Beecham Inc. Candy base and liquid center hard candy made therefrom
US4452825A (en) * 1982-09-01 1984-06-05 Nabisco Brands, Inc. Sorbitol-containing hard candy
CA1208558A (en) * 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
US4642231A (en) * 1983-07-20 1987-02-10 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates of antihistamines
US4749575A (en) * 1983-10-03 1988-06-07 Bio-Dar Ltd. Microencapsulated medicament in sweet matrix
US4551329A (en) * 1984-01-20 1985-11-05 Joan Harris Oral medicament lollipop
US4863737A (en) * 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
US4588580B2 (en) * 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
US4818539A (en) * 1985-02-05 1989-04-04 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
JP2801050B2 (ja) * 1985-05-01 1998-09-21 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデイション 圧縮粉末薬剤
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
US4671953A (en) * 1985-05-01 1987-06-09 University Of Utah Research Foundation Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics
US4695463A (en) * 1985-05-24 1987-09-22 Warner-Lambert Company Delivery system for active ingredients and preparation thereof
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
FR2611501B1 (fr) * 1987-03-04 1991-12-06 Corbiere Jerome Nouvelles compositions pharmaceutiques pour la voie buccale a base d'acetylsalielylate de lysine et leur procede d'obtention

Also Published As

Publication number Publication date
ATE177007T1 (de) 1999-03-15
DE69032982T2 (de) 1999-08-26
NO920857L (no) 1992-04-06
ES2133448T3 (es) 1999-09-16
EP0630647B1 (de) 1999-03-03
DK0630647T3 (da) 1999-10-04
WO1991003237A1 (en) 1991-03-21
CA2066423C (en) 1998-04-14
EP0490916A1 (de) 1992-06-24
CA2066423A1 (en) 1991-03-06
NO304348B1 (no) 1998-12-07
JP2717024B2 (ja) 1998-02-18
DE69023143T2 (de) 1996-03-28
EP0630647A1 (de) 1994-12-28
JPH05503917A (ja) 1993-06-24
AU5521894A (en) 1994-04-28
EP0490916A4 (en) 1992-08-12
ES2077686T3 (es) 1995-12-01
NO920857D0 (no) 1992-03-04
DE69023143D1 (de) 1995-11-23
US5288497A (en) 1994-02-22
EP0490916B1 (de) 1995-10-18
DE69032982D1 (de) 1999-04-08
DK0490916T3 (da) 1996-03-04
AU645265B2 (en) 1994-01-13
AU668004B2 (en) 1996-04-18
AU6287790A (en) 1991-04-08

Similar Documents

Publication Publication Date Title
ATE129148T1 (de) Zusammensetzungen und verfahren zur herstellung von im mund zersetzlichen heilmitteln.
EP0268463A3 (en) Zinc based ceramics
CA2066403A1 (en) Transmucosal dosage form
LV12572A (en) Method for introducing a 1,2 double bond into 4-azasteroids and crystalline phroscor(r) and pharmaceutical compositions thereof
YU83786A (en) Process for obtaining hypoglicemic thiazolidindione
FI941245A (fi) Menetelmä 2'-deoksiguanosiinin asyylijohdannaisten valmistamiseksi
DE3783257D1 (de) Peptid, dessen verfahren zur herstellung, sie enthaltende pharmazeutische zusammensetzung und benutzung.
PT92987A (pt) Processo para a preparcao de uma composicao anti-ulceras com base num agente como o sucralfato
HUT52040A (en) Process for producing diaryl-derivatives and pharmaceutical compositions containing them
DE59008170D1 (de) Verfahren zur Herstellung mikronisierter bioabbaubarer Partikel.
ATE191849T1 (de) Verwendung von (s)-(-)-alpha-ethyl-2-oxo-1- pyrrolidinacetamid zur herstellung eines medikaments zur behandlung von angst
DE68924714D1 (de) Verwendung von essentiellen fettsäuren zur herstellung eines medikaments zur behandlung von ekzemen.
HUT59600A (en) Process for producing pharmaceutical compositions containing 5-methyl-isoxazoe-4-carboxylik-anilides or alpha-/2-hydroxy-ethylidene/-alpha-cyano-acetic-anilides for treating eye-diseases
DE69029040D1 (de) Megakaryocytopoietischer faktor
DE3773716D1 (de) Verfahren zur herstellung von monosodiumsalz und dessen monohydrat von 1-beta-d-arabinofuranosylcytosin-5'stearylphosphat und diese enthaltende pharmazeutische zusammensetzung.
HUT44707A (en) Process for producing layered medicine form of prolonged effect containing agent resorpting through epidermis
IL98200A0 (en) Pharmaceutical composition containing a derivative of substituted-l-valyl-l-prolinamide
ZA852108B (en) Novel esters,their preparation and their use for controlling pests
HUT54682A (en) Process for producing 13-bromine- and 13,14-dibromine-ergoline derivatives and pharmaceutical preparatives containing these compounds
HUT44802A (en) Process for producing pseudo-oligosaccharides and pharmaceutical compositions containing them
DE2966199D1 (en) 6,7-cycloalkano-1,4-oxazepines, process for their preparation and medicines containing them
GR890100040A (el) Οδοντιατρικό κα?ρεπτάκι μιάς χρήσεως.
ATE32514T1 (de) 3-(4'-aminobutylamino)-propylamino-bleomycinderivate, verfahren zur ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE66373T1 (de) Verwendung des 2-amino-6-allyl-5,6,7,8-tetrahydro-4h-thiazolo( ,5-d>azepins zur herstellung eines zur behandlung der parkinsonschen erkrankung bzw. des parkinsonismus geeigneten arzneimittels.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee