ATE128464T1 - Carboximidamid-derivate. - Google Patents

Carboximidamid-derivate.

Info

Publication number
ATE128464T1
ATE128464T1 AT89124025T AT89124025T ATE128464T1 AT E128464 T1 ATE128464 T1 AT E128464T1 AT 89124025 T AT89124025 T AT 89124025T AT 89124025 T AT89124025 T AT 89124025T AT E128464 T1 ATE128464 T1 AT E128464T1
Authority
AT
Austria
Prior art keywords
disclosed
cyano
substituents
chem
preparing
Prior art date
Application number
AT89124025T
Other languages
English (en)
Inventor
Toshio Kirin Beer K K Izawa
Chome
Tomoko Kirin Beer Kashiwabara
-Chome Machi
Shohachi Kirin Beer K Nakajima
Nobuyuki Kirin Beer K K Ogawa
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP1298950A external-priority patent/JPH0662567B2/ja
Application filed by Kirin Brewery filed Critical Kirin Brewery
Application granted granted Critical
Publication of ATE128464T1 publication Critical patent/ATE128464T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT89124025T 1988-12-27 1989-12-27 Carboximidamid-derivate. ATE128464T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP33033688 1988-12-27
JP20417689 1989-08-07
JP1298950A JPH0662567B2 (ja) 1988-12-27 1989-11-17 ピリジンカルボキシイミダミド誘導体、その製造中間体、製造法および用途
JP30989889 1989-11-29

Publications (1)

Publication Number Publication Date
ATE128464T1 true ATE128464T1 (de) 1995-10-15

Family

ID=27476180

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89124025T ATE128464T1 (de) 1988-12-27 1989-12-27 Carboximidamid-derivate.

Country Status (12)

Country Link
EP (1) EP0388528B1 (de)
AT (1) ATE128464T1 (de)
AU (1) AU628453B2 (de)
CA (1) CA2006734C (de)
DE (1) DE68924416T2 (de)
DK (1) DK173309B1 (de)
ES (1) ES2080062T3 (de)
FI (1) FI95244C (de)
GR (1) GR3017662T3 (de)
HK (1) HK1000092A1 (de)
HU (1) HU219337B (de)
NO (1) NO178400C (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6075024A (en) 1991-11-27 2000-06-13 Sepracor Inc. Methods for treating infection using optically pure (S)-lomefloxacin
MX9300433A (es) * 1992-01-28 1994-07-29 Kirin Brewery Compuestos de piridincarboximidamina y composiciones farmaceuticas que los contienen.
CN105017078B (zh) * 2014-04-23 2017-02-15 中国科学院大连化学物理研究所 一种芳香醛催化转化制备亚胺酸酯的方法
UY38911A (es) 2019-10-09 2021-05-31 Bayer Ag Compuestos de heteroarilo-triazol como pesticidas, formulaciones, usos y métodos de uso de los mismos

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8000869A (nl) * 1979-02-16 1980-08-19 Eisai Co Ltd Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan.
DE2906489A1 (de) * 1979-02-20 1980-09-04 Bristol Myers Co Neue n-cyan-n'-alkinyl-s-(subst.)- isothioharnstoffe
GB8603780D0 (en) * 1986-02-15 1986-03-19 Smith Kline French Lab Chemical compounds

Also Published As

Publication number Publication date
CA2006734A1 (en) 1990-06-27
AU628453B2 (en) 1992-09-17
HK1000092A1 (en) 1997-11-21
DK666989A (da) 1990-06-28
EP0388528B1 (de) 1995-09-27
AU4730889A (en) 1990-07-05
DE68924416D1 (de) 1995-11-02
ES2080062T3 (es) 1996-02-01
DK666989D0 (da) 1989-12-27
HU219337B (en) 2001-03-28
CA2006734C (en) 1996-07-09
NO178400C (no) 1996-03-20
FI95244C (fi) 1996-01-10
HU678689D0 (en) 1990-03-28
DE68924416T2 (de) 1996-06-13
NO895252D0 (no) 1989-12-27
NO178400B (no) 1995-12-11
EP0388528A2 (de) 1990-09-26
GR3017662T3 (en) 1996-01-31
FI95244B (fi) 1995-09-29
EP0388528A3 (de) 1991-06-05
NO895252L (no) 1990-06-28
DK173309B1 (da) 2000-07-10
FI896228A0 (fi) 1989-12-22

Similar Documents

Publication Publication Date Title
PL306590A1 (en) Substituted heterocyclic carboxylamides, method obtaining them and their application as therapeutic agents
AU4257889A (en) Sulphonamido-phenylalkanoic acid derivatives having thromboxane A2 antagonist activity
ES8601181A1 (es) Procedimiento de preparacion del 4 (2-(2-tenoil)-amino-3,5- dibromofenil)-metil-amino-ciclohexanol
NO174711C (no) Analogifremgangsmåte for fremstilling av nye, terapeutisk aktive pyrimidindionderivater
EP0767170A4 (de) 4,6-diarylpyrimidin-derivate und deren salze
SE8605504D0 (sv) Novel chroman derivatives
FI874865A0 (fi) Menetelmä lääkeaineena käyttökelpoisten imidatsolidinonijohdannaisten valmistamiseksi
EP0270093A3 (de) Lactamderivate, Verfahren zu deren Herstellung, sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung zur Herstellung von aktiven therapeutischen Arzneimitteln
HUT50337A (en) Process for producing benzoxazine derivatives and pharmaceutical compositions comprising the compounds
DE68924416D1 (de) Carboximidamid-Derivate.
HUT64318A (en) Process for production benzodpyrane derivativs and pharmaceutical preparations containing these compounds as effective substance
EP0446921A3 (en) Optically active alkylene-dioxybenzene derivatives and their use in therapy
GB1497729A (en) Benzenesulphonyl ureas and process for their manufacture
ES8503655A1 (es) Un procedimiento para preparar nuevas dihidropiridinas.
HUT49110A (en) Process for producing ether derivatives and thioether derivatives, as well as pharmaceutical compositions comprising these compounds as active ingredient
DE69011174D1 (de) Catecholaminester.
GB1471546A (en) 1-acyl-4-substituted alkyl-piperazine or homopiperazine derivatives nad process for preparation thereof

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time