ES8601181A1 - Procedimiento de preparacion del 4 (2-(2-tenoil)-amino-3,5- dibromofenil)-metil-amino-ciclohexanol - Google Patents
Procedimiento de preparacion del 4 (2-(2-tenoil)-amino-3,5- dibromofenil)-metil-amino-ciclohexanolInfo
- Publication number
- ES8601181A1 ES8601181A1 ES540041A ES540041A ES8601181A1 ES 8601181 A1 ES8601181 A1 ES 8601181A1 ES 540041 A ES540041 A ES 540041A ES 540041 A ES540041 A ES 540041A ES 8601181 A1 ES8601181 A1 ES 8601181A1
- Authority
- ES
- Spain
- Prior art keywords
- antibronchopneumopathic
- activity
- compound
- preparation
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 4-Y2-(2-TENOIL)-AMINO-35-DIBROMOFENIL)-METIL-AMINOZ-CICLOHEXANOL. CONSISTE EN LA REACCION DE CONDENSACION DEL 4-Y(2-AMINO-35-DIBROMOFENIL)-METIL-AMINOZ-CICLOHEXANOL CON CLORURO DE 2-TENOILO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE TAL COMO TOLUENO EN PRESENCIA DE UN AGENTE ACEPTOR DE ACIDO TAL COMO CARBONATO O BICARBONATO ALCALINO O UNA AMINA TERCIARIA A UNA TEMPERATURA COMPRENDIDA ENTRE 10JC Y LA DE REFLUJO DEL DISOLVENTE. ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE AFECCIONES DEL APARATO RESPIRATORIO AGUDAS O CRONICAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8419374A IT1213132B (it) | 1984-02-02 | 1984-02-02 | Agente antibroncopneumopatico. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES540041A0 ES540041A0 (es) | 1985-11-01 |
ES8601181A1 true ES8601181A1 (es) | 1985-11-01 |
Family
ID=11157151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES540041A Expired ES8601181A1 (es) | 1984-02-02 | 1985-02-01 | Procedimiento de preparacion del 4 (2-(2-tenoil)-amino-3,5- dibromofenil)-metil-amino-ciclohexanol |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0150787B1 (es) |
AT (1) | ATE33835T1 (es) |
DE (2) | DE150787T1 (es) |
ES (1) | ES8601181A1 (es) |
IT (1) | IT1213132B (es) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1248702B (it) * | 1990-06-06 | 1995-01-26 | Yason Srl | Agente antitussivo e mucoregolatore,sua preparazione e composizioni farmaceutiche |
WO2014037832A2 (en) | 2012-09-06 | 2014-03-13 | Mahesh Kandula | Compositions and methods for the treatment of epilepsy and neurological diseases |
EP2847158A4 (en) | 2012-05-07 | 2015-12-30 | Cellix Bio Private Ltd | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS AND NEURODEGENERATIVE DISORDERS |
US9399634B2 (en) | 2012-05-07 | 2016-07-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of depression |
CA2872975A1 (en) | 2012-05-07 | 2013-11-14 | Cellixbio Private Limited | Compositions and methods for the treatment of neurological disorders |
US9266823B2 (en) | 2012-05-08 | 2016-02-23 | Cellix Bio Private Limited | Compositions and methods for the treatment of parkinson's disease |
US9522884B2 (en) | 2012-05-08 | 2016-12-20 | Cellix Bio Private Limited | Compositions and methods for the treatment of metabolic disorders |
US9403826B2 (en) | 2012-05-08 | 2016-08-02 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory disorders |
WO2013168025A1 (en) | 2012-05-08 | 2013-11-14 | Mahesh Kandula | Compositions and methods for treatment of blood clotting disorders |
US9434704B2 (en) | 2012-05-08 | 2016-09-06 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological degenerative disorders |
US9499527B2 (en) | 2012-05-10 | 2016-11-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of familial amyloid polyneuropathy |
US9233161B2 (en) | 2012-05-10 | 2016-01-12 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological conditions |
WO2013167997A2 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of metabolic syndrome |
WO2013168000A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of severe pain |
WO2013168011A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of chronic pain |
US9315461B2 (en) | 2012-05-10 | 2016-04-19 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurologic diseases |
WO2013168015A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of asthma and allergy |
WO2013168012A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of respiratory disorders |
WO2013168001A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for the treatment of moderate to severe pain |
SG11201407318UA (en) | 2012-05-10 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of metabolic syndrome |
US9339484B2 (en) | 2012-05-10 | 2016-05-17 | Cellix Bio Private Limited | Compositions and methods for the treatment of restless leg syndrome and fibromyalgia |
WO2013168033A1 (en) | 2012-05-10 | 2013-11-14 | Mahesh Kandula | Compositions and methods for treatment of neurologic diseases |
US9346742B2 (en) | 2012-05-10 | 2016-05-24 | Cellix Bio Private Limited | Compositions and methods for the treatment of fibromyalgia pain |
JP2015518855A (ja) | 2012-05-23 | 2015-07-06 | セリックスビオ プライヴェート リミテッド | 粘膜炎の治療のための組成物および方法 |
WO2013175347A2 (en) * | 2012-05-23 | 2013-11-28 | Mahesh Kandula | Compositions and methods for the treatment of respiratory disorders |
JP2015518854A (ja) | 2012-05-23 | 2015-07-06 | セリックスビオ プライヴェート リミテッド | 多発性硬化症の治療のための組成物および方法 |
JP6202287B2 (ja) | 2012-05-23 | 2017-09-27 | セリックスビオ プライヴェート リミテッド | 炎症性腸疾患の治療のための組成物及び方法 |
US9492409B2 (en) | 2012-05-23 | 2016-11-15 | Cellix Bio Private Limited | Compositions and methods for the treatment of local pain |
US9434729B2 (en) | 2012-05-23 | 2016-09-06 | Cellix Bio Private Limited | Compositions and methods for the treatment of periodontitis and rheumatoid arthritis |
US9108942B1 (en) | 2014-11-05 | 2015-08-18 | Mahesh Kandula | Compositions and methods for the treatment of moderate to severe pain |
WO2014020480A2 (en) | 2012-08-03 | 2014-02-06 | Mahesh Kandula | Compositions and methods for the treatment migraine and neurologic diseases |
US9624168B2 (en) | 2012-09-06 | 2017-04-18 | Cellix Bio Private Limited | Compositions and methods for the treatment inflammation and lipid disorders |
SG11201407325YA (en) | 2012-09-08 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for treatment of inflammation and lipid disorders |
US9333187B1 (en) | 2013-05-15 | 2016-05-10 | Cellix Bio Private Limited | Compositions and methods for the treatment of inflammatory bowel disease |
EP3004049B1 (en) | 2013-06-04 | 2018-09-05 | Cellixbio Private Limited | Compositions and methods for the treatment of diabetes and pre-diabetes |
US9096537B1 (en) | 2014-12-31 | 2015-08-04 | Mahesh Kandula | Compositions and methods for the treatment of mucositis |
EP3240779B1 (en) | 2014-09-26 | 2020-10-28 | Cellixbio Private Limited | Compositions and methods for the treatment of epilepsy and neurological disorders |
EP3201168B1 (en) | 2014-09-29 | 2020-03-18 | Cellix Bio Private Limited | Compounds and compositions for the treatment of multiple sclerosis |
CA2965449C (en) | 2014-10-27 | 2020-11-10 | Cellix Bio Private Limited | Three component salts of fumaric acid monomethyl ester with piperazine or ethylene diamine for the treatment of multiple sclerosis |
US9173877B1 (en) | 2014-11-05 | 2015-11-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of local pain |
US10208014B2 (en) | 2014-11-05 | 2019-02-19 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological disorders |
US9175008B1 (en) | 2014-11-05 | 2015-11-03 | Cellix Bio Private Limited | Prodrugs of anti-platelet agents |
US9150557B1 (en) | 2014-11-05 | 2015-10-06 | Cellix Bio Private Limited | Compositions and methods for the treatment of hyperglycemia |
US9321716B1 (en) | 2014-11-05 | 2016-04-26 | Cellix Bio Private Limited | Compositions and methods for the treatment of metabolic syndrome |
US9290486B1 (en) | 2014-11-05 | 2016-03-22 | Cellix Bio Private Limited | Compositions and methods for the treatment of epilepsy |
US9284287B1 (en) | 2014-11-05 | 2016-03-15 | Cellix Bio Private Limited | Compositions and methods for the suppression of carbonic anhydrase activity |
US9932294B2 (en) | 2014-12-01 | 2018-04-03 | Cellix Bio Private Limited | Compositions and methods for the treatment of multiple sclerosis |
US9206111B1 (en) | 2014-12-17 | 2015-12-08 | Cellix Bio Private Limited | Compositions and methods for the treatment of neurological diseases |
EP3242869B1 (en) | 2015-01-06 | 2021-10-27 | Cellixbio Private Limited | Compositions and methods for the treatment of inflammation and pain |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1593579B1 (de) * | 1966-05-10 | 1972-02-03 | Thomae Gmbh Dr K | Hydroxy-cyclohexylamine,deren physiologisch vertraeglichen Saeureadditionssalze und Verfahren zu ihrer Herstellung |
-
1984
- 1984-02-02 IT IT8419374A patent/IT1213132B/it active
-
1985
- 1985-01-20 DE DE198585100563T patent/DE150787T1/de active Pending
- 1985-01-20 EP EP85100563A patent/EP0150787B1/en not_active Expired
- 1985-01-20 DE DE8585100563T patent/DE3562374D1/de not_active Expired
- 1985-01-20 AT AT85100563T patent/ATE33835T1/de not_active IP Right Cessation
- 1985-02-01 ES ES540041A patent/ES8601181A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
IT1213132B (it) | 1989-12-14 |
EP0150787B1 (en) | 1988-04-27 |
EP0150787A3 (en) | 1985-08-21 |
ES540041A0 (es) | 1985-11-01 |
DE150787T1 (de) | 1986-01-02 |
DE3562374D1 (en) | 1988-06-01 |
IT8419374A0 (it) | 1984-02-02 |
EP0150787A2 (en) | 1985-08-07 |
ATE33835T1 (de) | 1988-05-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8601181A1 (es) | Procedimiento de preparacion del 4 (2-(2-tenoil)-amino-3,5- dibromofenil)-metil-amino-ciclohexanol | |
DE69022453D1 (de) | N-(3-Hydroxy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran oder dihydrobenzodioxin)-carboxamid-Derivate. | |
EP0363212A3 (en) | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | |
NO851933L (no) | Fremgangsmaate ved fremstilling av terapeutisk aktivt (5)-alfa-ethyl-2-oxo-1-pyrrolidinacetamid. | |
DK74691D0 (da) | 4(4-(substitueret phenyl)-1-piperazinyl)phenoler og fremgangsmaade til fremstilling deraf | |
EP0353955A3 (en) | Novel compounds | |
DE3674448D1 (de) | N-((4-piperidinyl)-alkyl)-substituierte bicyclische kondensierte oxazol- und thiazolamine. | |
EP0270093A3 (en) | Lactam derivatives, processes for the preparation thereof, pharmaceutical compositions comprising the same, and the use of such derivatives for the manufacture of a medicament having valuable therapeutic properties | |
GB1453703A (en) | Substituted cyclopropylmethylamines processes for their preparation and pharmaceutical compositions containing them | |
DE3164741D1 (en) | 2-(4-(diphenylmethylene)-1-piperidinyl)-acetic acids and their amides, their preparation and pharmaceutical preparations containing them | |
KR960009422B1 (en) | 4-(ardylamino)piperidinebutanamide derivatives | |
GB1497729A (en) | Benzenesulphonyl ureas and process for their manufacture | |
GB1450801A (en) | Pyridinecarboxamide sulphonylurea hypoglycemic agents | |
HU903092D0 (en) | Process for the preparation of buten-carboxylic acid derivatives and pharmaceutical compositions containing such compounds | |
DE3668888D1 (de) | Ein imidazolidintrion-derivat oder ein seiner pharmazeutisch akzeptierbaren salze enthaltende pharmazeutische zusammenstellung. | |
ATE128464T1 (de) | Carboximidamid-derivate. | |
SE8204670D0 (sv) | Ny forening med antiulcerogen aktivitet, forfarande for dess framstellning och farmaceutisk beredning innehallande densamma | |
JPS5753481A (en) | 4-hydrouracil-piperidines | |
JPS5740408A (en) | Hypoglycemic | |
DK158513C (da) | N-(substitueret phenyl)-n'-pyridinylurinstoffer, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende disse | |
IL61234A (en) | Guanidino thiazolyl alkylamino(alkylthioalkylamino)nitrotetrahydropyridines,process for preparing them and pharmaceutical compositions containing them | |
JPS6485966A (en) | Benzoylurea-based compound, harmful animal controller containing said compound and production thereof | |
JPS57169463A (en) | Preparation of carbostyril derivative | |
KR860000284A (ko) | 디하이드로피리딘의 제조방법 |