ATE120192T1 - Verfahren zur herstellung von diltiazem. - Google Patents

Verfahren zur herstellung von diltiazem.

Info

Publication number
ATE120192T1
ATE120192T1 AT92900248T AT92900248T ATE120192T1 AT E120192 T1 ATE120192 T1 AT E120192T1 AT 92900248 T AT92900248 T AT 92900248T AT 92900248 T AT92900248 T AT 92900248T AT E120192 T1 ATE120192 T1 AT E120192T1
Authority
AT
Austria
Prior art keywords
pct
date jun
benzothiazepin
methoxyphenyl
dihydro
Prior art date
Application number
AT92900248T
Other languages
English (en)
Inventor
Elso Manghisi
Bruno Perego
Original Assignee
Lusochimica Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lusochimica Spa filed Critical Lusochimica Spa
Application granted granted Critical
Publication of ATE120192T1 publication Critical patent/ATE120192T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT92900248T 1990-12-11 1991-12-09 Verfahren zur herstellung von diltiazem. ATE120192T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02234090A IT1244878B (it) 1990-12-11 1990-12-11 Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato

Publications (1)

Publication Number Publication Date
ATE120192T1 true ATE120192T1 (de) 1995-04-15

Family

ID=11194922

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92900248T ATE120192T1 (de) 1990-12-11 1991-12-09 Verfahren zur herstellung von diltiazem.

Country Status (10)

Country Link
US (1) US5382663A (de)
EP (1) EP0561861B1 (de)
JP (1) JP3152658B2 (de)
AT (1) ATE120192T1 (de)
AU (1) AU9036691A (de)
CA (1) CA2098114C (de)
DE (1) DE69108410T2 (de)
ES (1) ES2070622T3 (de)
IT (1) IT1244878B (de)
WO (1) WO1992010485A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1255545B (it) * 1992-10-23 1995-11-09 Procedimento per la preparazione di diltiazem
DE69411387T2 (de) * 1994-09-16 1999-02-25 Orion Corp Fermion Verfahren zur Herstellung von pharmazeutisch aktiven Benzothiazepinderivaten.
FI97725C (fi) * 1995-02-17 1997-02-10 Orion Yhtymae Oy Menetelmä diltiatseemin valmistamiseksi
WO1996038429A1 (en) * 1995-06-01 1996-12-05 Acic (Canada) Inc. Method for the manufacture of benzothiazepine derivatives
US8397998B1 (en) 1999-10-23 2013-03-19 Ultracard, Inc. Data storage device, apparatus and method for using same
FR3033701B1 (fr) 2015-03-19 2021-01-15 Univ Claude Bernard Lyon Nouvelles compositions antivirales pour le traitement de la grippe
CN116143723A (zh) * 2022-12-07 2023-05-23 海南锦瑞制药有限公司 一种盐酸地尔硫卓的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71538A (en) * 1984-04-13 1987-07-31 Abic Ltd Process for the preparation of benzothiazepine derivatives
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
IT1226301B (it) * 1988-07-26 1990-12-27 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem.

Also Published As

Publication number Publication date
JP3152658B2 (ja) 2001-04-03
DE69108410D1 (de) 1995-04-27
ES2070622T3 (es) 1995-06-01
CA2098114A1 (en) 1992-06-11
AU9036691A (en) 1992-07-08
DE69108410T2 (de) 1995-08-10
IT9022340A1 (it) 1992-06-11
IT9022340A0 (it) 1990-12-11
IT1244878B (it) 1994-09-12
CA2098114C (en) 2002-06-25
US5382663A (en) 1995-01-17
EP0561861A1 (de) 1993-09-29
WO1992010485A1 (en) 1992-06-25
EP0561861B1 (de) 1995-03-22
JPH06503317A (ja) 1994-04-14

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Legal Events

Date Code Title Description
EELA Cancelled due to lapse of time