ATE113833T1 - Aromatische und heteroaromatische amine zur behandlung von depressionen, hirnleistungsstörungen und dementia. - Google Patents
Aromatische und heteroaromatische amine zur behandlung von depressionen, hirnleistungsstörungen und dementia.Info
- Publication number
- ATE113833T1 ATE113833T1 AT90306020T AT90306020T ATE113833T1 AT E113833 T1 ATE113833 T1 AT E113833T1 AT 90306020 T AT90306020 T AT 90306020T AT 90306020 T AT90306020 T AT 90306020T AT E113833 T1 ATE113833 T1 AT E113833T1
- Authority
- AT
- Austria
- Prior art keywords
- lower alkyl
- carbon atoms
- optionally substituted
- depression
- dementia
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/32—Isothioureas having sulfur atoms of isothiourea groups bound to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/50—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/13—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
- C07C309/14—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Lubricants (AREA)
- Furan Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898912784A GB8912784D0 (en) | 1989-06-02 | 1989-06-02 | Amines |
GB898927087A GB8927087D0 (en) | 1989-11-30 | 1989-11-30 | Amines |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE113833T1 true ATE113833T1 (de) | 1994-11-15 |
Family
ID=26295435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90306020T ATE113833T1 (de) | 1989-06-02 | 1990-06-01 | Aromatische und heteroaromatische amine zur behandlung von depressionen, hirnleistungsstörungen und dementia. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5086073A (de) |
EP (1) | EP0407032B1 (de) |
JP (1) | JPH0347155A (de) |
KR (1) | KR910000133A (de) |
AT (1) | ATE113833T1 (de) |
AU (1) | AU641394B2 (de) |
CA (1) | CA2017966A1 (de) |
DE (1) | DE69013994T2 (de) |
ES (1) | ES2063268T3 (de) |
GB (1) | GB2233558B (de) |
HU (1) | HUT58270A (de) |
PT (1) | PT94218A (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5430044A (en) * | 1987-02-06 | 1995-07-04 | Fisons Corporation | Arylalkyl-amines and -amides having anticonvulsant and neuroprotective properties |
GB9125615D0 (en) * | 1991-12-02 | 1992-01-29 | Wyeth John & Brother Ltd | Amines |
GB9320051D0 (en) * | 1993-09-29 | 1993-11-17 | Lilly Industries Ltd | Pharmaceutical compounds |
EP1115393A4 (de) * | 1998-07-31 | 2002-03-26 | Lilly Co Eli | Sulfonamidderivate |
GB0417802D0 (en) * | 2004-08-10 | 2004-09-15 | Novartis Ag | Organic compounds |
US8604055B2 (en) | 2004-12-31 | 2013-12-10 | Dr. Reddy's Laboratories Ltd. | Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors |
KR101238525B1 (ko) | 2004-12-31 | 2013-02-28 | 레디 유에스 테라퓨틱스 인코포레이티드 | Cetp 저해제로서의 신규 벤질아민 유도체 |
CA2845284C (en) | 2011-08-18 | 2018-03-06 | Dr. Reddy's Laboratories Ltd. | Substituted heterocyclic amine compounds as cholesteryl ester-transfer protein (cetp) inhibitors |
KR101803866B1 (ko) | 2011-09-27 | 2017-12-04 | 닥터 레디스 레보러터리즈 리미티드 | 동맥경화증 치료에 유용한 콜레스테릴 에스테르-전달 단백질(cetp) 억제제로서 5-벤질아미노메틸-6-아미노피라졸로[3,4-b]피리딘 유도체 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB841634A (en) * | 1957-04-17 | 1960-07-20 | Ici Ltd | Triphenylmethane derivatives and their use in molluscicidal compositions |
GB942309A (en) * | 1959-02-06 | 1963-11-20 | Wellcome Found | Tertiary n-bromobenzyl-n-butylamines and their preparation |
DE1116227B (de) * | 1959-07-09 | 1961-11-02 | Thomae Gmbh Dr K | Verfahren zur Herstellung von tertiaeren Aminen |
CH419131A (fr) * | 1961-01-31 | 1966-08-31 | Olin Mathieson | Procédé de préparation de dihydrodibenzothiazépines |
DE1227447B (de) * | 1962-03-30 | 1966-10-27 | Chinoin Gyogyszer Es Vegyeszet | Verfahren zur Herstellung von Phenylisopropylaminen |
GB1031425A (en) * | 1962-03-30 | 1966-06-02 | Chinoin Gyogyszer Es Vegyeszet | New aralkylamines and their preparation |
CA943127A (en) * | 1970-01-19 | 1974-03-05 | Crompton And Knowles Corporation | Dye intermediates, dyestuffs prepared therefrom and process for making dyes and intermediates |
JPS4740907Y1 (de) * | 1970-09-19 | 1972-12-11 | ||
US3956078A (en) * | 1972-12-14 | 1976-05-11 | M & T Chemicals Inc. | Electrodeposition of copper |
CS163580B1 (de) * | 1973-04-10 | 1975-09-15 | ||
IE40727B1 (en) * | 1974-03-09 | 1979-08-01 | Hoechst Ag | Aralkylamines |
GB1532957A (en) * | 1974-11-04 | 1978-11-22 | Glaxo Lab Ltd | Bis(aminomethyl)naphthalene derivatives |
DE2940509C2 (de) * | 1978-10-06 | 1995-01-26 | Nippon Paint Co Ltd | Polymerisierbare Aminosäureverbindungen und ihre Verwendung |
EP0177078A1 (de) * | 1984-09-12 | 1986-04-09 | Duphar International Research B.V | Spasmolytisch wirksame tertiäre Aminderivate und Verfahren zu ihrer Herstellung |
US4647591A (en) * | 1985-10-07 | 1987-03-03 | Eli Lilly And Company | Method for improving memory |
EG18188A (en) * | 1986-05-01 | 1992-09-30 | Pfizer Ltd | Process for preparation anti-arhythmia agents |
US4649161A (en) * | 1986-06-16 | 1987-03-10 | Massachusetts Institute Of Technology | Method for treating depression with d-fenfluramine |
HU207280B (en) * | 1986-09-25 | 1993-03-29 | Chinoin Gyogyszer Es Vegyeszet | Process for producing new phenyl-alkyl-amines and pharmaceutical compositions containing them |
NL8700842A (de) * | 1987-04-10 | 1988-11-01 | Duphar Int Res | |
JP2581707B2 (ja) * | 1987-10-02 | 1997-02-12 | 科研製薬株式会社 | 抗真菌剤組成物 |
GB8813185D0 (en) * | 1988-06-03 | 1988-07-06 | Wyeth John & Brother Ltd | New method & amines used therein |
-
1990
- 1990-05-30 HU HU903266A patent/HUT58270A/hu unknown
- 1990-05-30 AU AU56080/90A patent/AU641394B2/en not_active Ceased
- 1990-05-30 US US07/530,758 patent/US5086073A/en not_active Expired - Fee Related
- 1990-05-31 PT PT94218A patent/PT94218A/pt not_active Application Discontinuation
- 1990-05-31 KR KR1019900007947A patent/KR910000133A/ko not_active Application Discontinuation
- 1990-05-31 CA CA002017966A patent/CA2017966A1/en not_active Abandoned
- 1990-05-31 JP JP2143236A patent/JPH0347155A/ja active Pending
- 1990-06-01 GB GB9012223A patent/GB2233558B/en not_active Expired - Fee Related
- 1990-06-01 DE DE69013994T patent/DE69013994T2/de not_active Expired - Fee Related
- 1990-06-01 AT AT90306020T patent/ATE113833T1/de not_active IP Right Cessation
- 1990-06-01 EP EP90306020A patent/EP0407032B1/de not_active Expired - Lifetime
- 1990-06-01 ES ES90306020T patent/ES2063268T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
PT94218A (pt) | 1991-02-08 |
DE69013994D1 (de) | 1994-12-15 |
GB9012223D0 (en) | 1990-07-18 |
JPH0347155A (ja) | 1991-02-28 |
EP0407032B1 (de) | 1994-11-09 |
DE69013994T2 (de) | 1995-04-13 |
HU903266D0 (en) | 1990-10-28 |
EP0407032A2 (de) | 1991-01-09 |
GB2233558B (en) | 1993-12-15 |
GB2233558A (en) | 1991-01-16 |
EP0407032A3 (en) | 1992-01-02 |
KR910000133A (ko) | 1991-01-29 |
US5086073A (en) | 1992-02-04 |
HUT58270A (en) | 1992-02-28 |
ES2063268T3 (es) | 1995-01-01 |
CA2017966A1 (en) | 1990-12-02 |
AU641394B2 (en) | 1993-09-23 |
AU5608090A (en) | 1990-12-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |