ATE112680T1 - Photoempfindliche mittel. - Google Patents

Photoempfindliche mittel.

Info

Publication number
ATE112680T1
ATE112680T1 AT89908664T AT89908664T ATE112680T1 AT E112680 T1 ATE112680 T1 AT E112680T1 AT 89908664 T AT89908664 T AT 89908664T AT 89908664 T AT89908664 T AT 89908664T AT E112680 T1 ATE112680 T1 AT E112680T1
Authority
AT
Austria
Prior art keywords
compounds
tissue
pyropheophorbide
photodynamic therapy
tumor
Prior art date
Application number
AT89908664T
Other languages
English (en)
Inventor
Ravindra K Pandey
Thomas John Dougherty
Original Assignee
Health Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Research Inc filed Critical Health Research Inc
Application granted granted Critical
Publication of ATE112680T1 publication Critical patent/ATE112680T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Light Receiving Elements (AREA)
  • Radiation-Therapy Devices (AREA)
AT89908664T 1988-07-20 1989-07-19 Photoempfindliche mittel. ATE112680T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/221,804 US5002962A (en) 1988-07-20 1988-07-20 Photosensitizing agents

Publications (1)

Publication Number Publication Date
ATE112680T1 true ATE112680T1 (de) 1994-10-15

Family

ID=22829459

Family Applications (1)

Application Number Title Priority Date Filing Date
AT89908664T ATE112680T1 (de) 1988-07-20 1989-07-19 Photoempfindliche mittel.

Country Status (7)

Country Link
US (3) US5002962A (de)
EP (1) EP0425566B1 (de)
JP (1) JPH04500955A (de)
AT (1) ATE112680T1 (de)
AU (1) AU641362B2 (de)
DE (1) DE68918860T2 (de)
WO (1) WO1990000895A1 (de)

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US5219878A (en) * 1990-10-05 1993-06-15 Queen's University Tetrapyrrole hydroxyalkylamide photochemotherapeutic agents
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US6100392A (en) * 1992-08-14 2000-08-08 The Trustees Of The University Of Pennsylavania Electron-deficient porphyrins and processes and intermediates for preparing same
US5422362A (en) * 1993-07-29 1995-06-06 Quadra Logic Technologies, Inc. Method to inhibit restenosis
US5492924A (en) * 1993-09-24 1996-02-20 Fox Chase Cancer Center Phorbine derivatives and their use in the diagnosis and therapy of cancer
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US5882328A (en) * 1995-01-13 1999-03-16 Qlt Phototherapeutics, Inc. Method to prevent transplant rejection
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Also Published As

Publication number Publication date
DE68918860D1 (de) 1994-11-17
AU641362B2 (en) 1993-09-23
US5459159A (en) 1995-10-17
US5002962A (en) 1991-03-26
EP0425566B1 (de) 1994-10-12
DE68918860T2 (de) 1995-02-16
JPH04500955A (ja) 1992-02-20
WO1990000895A1 (en) 1990-02-08
US5314905A (en) 1994-05-24
EP0425566A4 (en) 1992-03-11
EP0425566A1 (de) 1991-05-08
AU3971489A (en) 1990-02-19

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