ATE111224T1 - Kapillare durchflussvorrichtung und verfahren zur messung der aktivierten partiellen thromboplastinzeit. - Google Patents

Kapillare durchflussvorrichtung und verfahren zur messung der aktivierten partiellen thromboplastinzeit.

Info

Publication number
ATE111224T1
ATE111224T1 AT90304300T AT90304300T ATE111224T1 AT E111224 T1 ATE111224 T1 AT E111224T1 AT 90304300 T AT90304300 T AT 90304300T AT 90304300 T AT90304300 T AT 90304300T AT E111224 T1 ATE111224 T1 AT E111224T1
Authority
AT
Austria
Prior art keywords
partial thromboplastin
activated partial
thromboplastin time
measurement
flow device
Prior art date
Application number
AT90304300T
Other languages
English (en)
Inventor
Katheryne M Mcdonald
Laura J Winfrey
Michael M Gorin
James L Hill
Po Choo Hsu
Original Assignee
Biotrack Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotrack Inc filed Critical Biotrack Inc
Application granted granted Critical
Publication of ATE111224T1 publication Critical patent/ATE111224T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Optical Measuring Cells (AREA)
AT90304300T 1989-04-20 1990-04-20 Kapillare durchflussvorrichtung und verfahren zur messung der aktivierten partiellen thromboplastinzeit. ATE111224T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/341,045 US5039617A (en) 1989-04-20 1989-04-20 Capillary flow device and method for measuring activated partial thromboplastin time

Publications (1)

Publication Number Publication Date
ATE111224T1 true ATE111224T1 (de) 1994-09-15

Family

ID=23336031

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90304300T ATE111224T1 (de) 1989-04-20 1990-04-20 Kapillare durchflussvorrichtung und verfahren zur messung der aktivierten partiellen thromboplastinzeit.

Country Status (9)

Country Link
US (1) US5039617A (de)
EP (1) EP0394070B1 (de)
JP (1) JPH0751078B2 (de)
AT (1) ATE111224T1 (de)
AU (1) AU622541B2 (de)
CA (1) CA1334928C (de)
DE (1) DE69012195T2 (de)
ES (1) ES2071764T3 (de)
WO (1) WO1990013034A1 (de)

Families Citing this family (150)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164598A (en) * 1985-08-05 1992-11-17 Biotrack Capillary flow device
US5286454A (en) * 1989-04-26 1994-02-15 Nilsson Sven Erik Cuvette
US5296379A (en) * 1990-03-23 1994-03-22 Peter Gorog Apparatus and method for modeling arterial thrombus formations
US5569590A (en) * 1990-04-17 1996-10-29 Analytical Control Systems, Inc. Initial screen for abnormal platelet condition
DE69120674T2 (de) * 1990-04-17 1996-11-07 Analytical Control Syst Inc Koagulationsassays und reagenzien
US5316952A (en) * 1991-02-15 1994-05-31 Technical Research Associates, Inc. Blood sample apparatus and method
US5223219A (en) * 1992-04-10 1993-06-29 Biotrack, Inc. Analytical cartridge and system for detecting analytes in liquid samples
EP0645012B1 (de) * 1992-06-09 2001-08-01 Medical Devices Corporation Vorrichtung und verfahren zur optischen, hämostatischen blutanalyse
US5637452A (en) * 1992-10-02 1997-06-10 Analytical Control Systems, Inc. Kit for an initial screen for abnormal platelet condition comprising propyl gallate or tannin and a metal ion
US5500187A (en) * 1992-12-08 1996-03-19 Westinghouse Electric Corporation Disposable optical agglutination assay device and method for use
US5302348A (en) * 1992-12-10 1994-04-12 Itc Corporation Blood coagulation time test apparatus and method
US5491095A (en) * 1993-05-26 1996-02-13 Westinghouse Electric Corp. System and method for aggulutination detection
US5378431A (en) * 1993-06-14 1995-01-03 Becton, Dickinson And Company Dual pathway clotting enhancer for blood collection tube
ATE177536T1 (de) * 1993-06-30 1999-03-15 Diagnostische Forsch Stiftung Messung des aktivierten partiellen thromboplastinzeit (aptt) in einer einstufen- reaktion
US5522255A (en) * 1993-08-31 1996-06-04 Boehringer Mannheim Corporation Fluid dose, flow and coagulation sensor for medical instrument
US5447440A (en) * 1993-10-28 1995-09-05 I-Stat Corporation Apparatus for assaying viscosity changes in fluid samples and method of conducting same
US5478751A (en) * 1993-12-29 1995-12-26 Abbott Laboratories Self-venting immunodiagnositic devices and methods of performing assays
CA2143365A1 (en) * 1994-03-14 1995-09-15 Hugh V. Cottingham Nucleic acid amplification method and apparatus
US5612187A (en) * 1994-03-22 1997-03-18 Espress Tech, Inc. Clot lysis time determining device and method for determining the time necessary for fluid to lyse a clot, and clot supporter
US5432084A (en) * 1994-03-22 1995-07-11 Espress Tech, Inc. Device for in vitro bleeding time determination
FR2721714B1 (fr) * 1994-06-23 1996-09-06 Karim Boulhimez Dispositif d'évaluation de l'activité coagulante sanguine d'un échantillon biologique, jetable après usage unique, et procédé de mise en Óoeuvre.
US5504011A (en) * 1994-10-21 1996-04-02 International Technidyne Corporation Portable test apparatus and associated method of performing a blood coagulation test
US5760894A (en) * 1995-02-13 1998-06-02 Point Source, Inc. Liquid sample analysis in an optical fourier transform system
US5559596A (en) * 1995-02-13 1996-09-24 Point Source, Inc. Fluid sample analysis by optical fourier transform imaging
EP1062510A2 (de) 1998-03-10 2000-12-27 Strategic Diagnostics Inc. Integriertes testgerät und verfahren zur produktion und verwendung
US7021122B1 (en) 1998-03-19 2006-04-04 Orgenics Biosensors Ltd. Device for the determination of blood clotting by capacitance or resistance
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
AU3771599A (en) * 1998-05-18 1999-12-06 University Of Washington Liquid analysis cartridge
US6830729B1 (en) 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
US6830934B1 (en) * 1999-06-15 2004-12-14 Lifescan, Inc. Microdroplet dispensing for a medical diagnostic device
US6521182B1 (en) * 1998-07-20 2003-02-18 Lifescan, Inc. Fluidic device for medical diagnostics
CA2254223A1 (en) 1998-11-16 2000-05-16 Biophys, Inc. Device and method for analyzing a biologic sample
US6451610B1 (en) * 1999-04-14 2002-09-17 International Technidyne Corporation Method and apparatus for coagulation based assays
CA2382143C (en) 1999-09-03 2005-10-18 Roche Diagnostics Corporation Method, reagent and test cartridge for determining clotting time
US6696240B1 (en) 1999-10-26 2004-02-24 Micronix, Inc. Capillary test strip to separate particulates
US6319719B1 (en) 1999-10-28 2001-11-20 Roche Diagnostics Corporation Capillary hematocrit separation structure and method
WO2001036666A1 (en) * 1999-11-15 2001-05-25 I-Stat Corporation Apparatus and method for assaying coagulation in fluid samples
US6406672B1 (en) 2000-01-28 2002-06-18 Roche Diagnostics Plasma retention structure providing internal flow
US6451264B1 (en) * 2000-01-28 2002-09-17 Roche Diagnostics Corporation Fluid flow control in curved capillary channels
US6438498B1 (en) * 2000-02-10 2002-08-20 I-Stat Corporation System, method and computer implemented process for assaying coagulation in fluid samples
US6448024B1 (en) * 2000-10-03 2002-09-10 Roche Diagnostics Corporation Method, reagent, cartridge, and device for determining fibrinogen
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
GB0030929D0 (en) * 2000-12-19 2001-01-31 Inverness Medical Ltd Analyte measurement
US6632678B2 (en) * 2001-01-03 2003-10-14 Sienco, Inc. Method for performing activated clotting time test with reduced sensitivity to the presence of aprotinin and for assessing aprotinin sensitivity
US6759009B2 (en) * 2001-05-04 2004-07-06 Portascience Incorporated Method and device for clotting time assay
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
WO2002100460A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
CA2448902C (en) 2001-06-12 2010-09-07 Pelikan Technologies, Inc. Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties
US7776608B2 (en) * 2001-07-09 2010-08-17 Bayer Healthcare Llc Volume meter testing device and method of use
DE10140699A1 (de) * 2001-08-24 2003-03-13 Roche Diagnostics Gmbh Anordnung und Verfahren zur Untersuchung der Fließfähigkeit einer physiologischen Flüssigprobe
US6989891B2 (en) 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
US7713214B2 (en) 2002-04-19 2010-05-11 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7604775B2 (en) * 2002-08-12 2009-10-20 Bayer Healthcare Llc Fluid collecting and monitoring device
AU2003267147A1 (en) 2002-09-10 2004-04-30 Placor, Inc. Method and device for monitoring platelet function
WO2004044560A1 (en) * 2002-11-12 2004-05-27 Inverness Medical Switzerland Gmbh Photometric determination of coagulation time in undiluted whole blood
US7291310B2 (en) * 2002-12-17 2007-11-06 The Regents Of The University Of Michigan Microsystem for determining clotting time of blood and low-cost, single-use device for use therein
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7071001B2 (en) 2003-01-10 2006-07-04 Dnk Associates, Inc. System and method for in vitro bleeding time testing
DE602004028463D1 (de) 2003-05-30 2010-09-16 Pelikan Technologies Inc Verfahren und vorrichtung zur injektion von flüssigkeit
WO2004107964A2 (en) 2003-06-06 2004-12-16 Pelikan Technologies, Inc. Blood harvesting device with electronic control
GB0313015D0 (en) * 2003-06-06 2003-07-09 Hall Effect Technologies Ltd Method and device for analysing a liquid
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
DE10354806A1 (de) * 2003-11-21 2005-06-02 Boehringer Ingelheim Microparts Gmbh Probenträger
DE10360220A1 (de) * 2003-12-20 2005-07-21 Steag Microparts Gmbh Mikrostrukturierte Anordnung zur blasenfreien Befüllung zumindest eines Systems zur Ableitung von Flüssigkeiten, Vorrichtung mit einer solchen Anordnung und Befüllungsverfahren
EP1706026B1 (de) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Verfahren und vorrichtung zur verbesserung der fluidströmung und der probennahme
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
US7439069B2 (en) 2004-02-27 2008-10-21 Nippoldt Douglas D Blood coagulation test cartridge, system, and method
US7422905B2 (en) 2004-02-27 2008-09-09 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US7399637B2 (en) 2004-04-19 2008-07-15 Medtronic, Inc. Blood coagulation test cartridge, system, and method
US20050250217A1 (en) * 2004-05-07 2005-11-10 Rich Keenan Vent configuration for sample element
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US20060195045A1 (en) 2005-02-14 2006-08-31 Gable Jennifer H Fluid handling cassette having a fluid transport network
US20060269978A1 (en) * 2005-04-25 2006-11-30 Haworth William S Method and device for monitoring platelet function
JP2006308366A (ja) * 2005-04-27 2006-11-09 Hitachi High-Technologies Corp 化学分析装置及び化学分析カートリッジ
KR101762424B1 (ko) 2005-05-09 2017-07-28 테라노스, 인코포레이티드 현장진료 유체 시스템 및 그 용도
CA2615278A1 (en) * 2005-08-31 2007-03-08 Egomedical Technologies Ag Coagulation test system
US9561001B2 (en) 2005-10-06 2017-02-07 Optiscan Biomedical Corporation Fluid handling cassette system for body fluid analyzer
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US8741230B2 (en) 2006-03-24 2014-06-03 Theranos, Inc. Systems and methods of sample processing and fluid control in a fluidic system
US7837941B2 (en) * 2006-04-07 2010-11-23 Agamatrix, Inc. Method and apparatus for monitoring alteration of flow characteristics in a liquid sample
WO2007133456A2 (en) * 2006-05-08 2007-11-22 Bayer Healthcare Llc Test sensor with under-fill protection
EP2023805B1 (de) * 2006-05-24 2012-07-04 Tarilian Laser Technologies, Limited Optisches lebenszeichendetektionsverfahren und messeinrichtung
US20080071180A1 (en) * 2006-05-24 2008-03-20 Tarilian Laser Technologies, Limited Vital Sign Detection Method and Measurement Device
WO2008070324A2 (en) * 2006-10-25 2008-06-12 Placor, Inc. Methods and devices for monitoring platelet function
KR101486405B1 (ko) 2007-01-31 2015-01-26 타릴리안 레이저 테크놀로지스, 리미티드 광 파워 변조
EP2040073A1 (de) * 2007-09-20 2009-03-25 Iline Microsystems, S.L. Mikrofluidische Vorrichtung und Verfahren zur Flüssigkeitsgerinnungs-Zeitbestimmung
US7821620B2 (en) * 2007-10-03 2010-10-26 University Of Central Florida Research Foundation, Inc. Optical coagulation monitor and method of use
US8425840B2 (en) * 2007-11-26 2013-04-23 Fujimori Kogyo Co., Ltd. Microchip and blood monitoring device
SE533103C2 (sv) * 2008-04-01 2010-06-29 Tommy Forsell Blodviskositetsanalys
EP2265324B1 (de) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Integriertes System zur Messung von Analyten
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
WO2010122158A1 (en) 2009-04-23 2010-10-28 Dublin City University A lateral flow assay device for coagulation monitoring and method thereof
US20110065101A1 (en) 2009-06-04 2011-03-17 Lockheed Martin Corporation Multiple-sample microfluidic chip for DNA analysis
US9554742B2 (en) 2009-07-20 2017-01-31 Optiscan Biomedical Corporation Fluid analysis system
US8731638B2 (en) 2009-07-20 2014-05-20 Optiscan Biomedical Corporation Adjustable connector and dead space reduction
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP3156796A1 (de) 2010-06-09 2017-04-19 Optiscan Biomedical Corporation Messung von analyten in einer flüssigkeitsprobe aus einem patienten
GB201014316D0 (en) 2010-08-27 2010-10-13 Univ Dublin City A agglutination assay method and device
GB2497501A (en) 2010-10-15 2013-06-12 Lockheed Corp Micro fluidic optic design
EP2729784A4 (de) 2011-07-06 2015-05-13 Optiscan Biomedical Corp Messzelle für flüssigkeitsanalysesystem
US9322054B2 (en) 2012-02-22 2016-04-26 Lockheed Martin Corporation Microfluidic cartridge
US10001495B2 (en) 2012-07-25 2018-06-19 Bioverativ Therapeutics Inc. Blood factor monitoring assay and uses thereof
US9651567B2 (en) 2013-05-14 2017-05-16 Cgt Enterprises, Llc Test strips for determining coagulation factor activities
US9562914B2 (en) 2013-10-16 2017-02-07 President And Fellows Of Harvard College Microfluidic device for real-time clinical monitoring and quantitative assessment of whole blood coagulation
CN107076733B (zh) 2014-09-09 2021-04-30 佩罗斯芬尔技术有限公司 基于微流控芯片的通用凝血测定
WO2016049506A1 (en) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Sensors for assaying coagulation in fluid samples
CN106999932A (zh) 2014-09-26 2017-08-01 雅培医护站股份有限公司 用于流体样本中的凝结测定的具有流体结的盒设备
CN107107057B (zh) 2014-09-26 2020-12-15 雅培医护站股份有限公司 用于流体样本中的凝结测定的盒设备识别
EP3198281B1 (de) 2014-09-26 2023-01-25 Abbott Point Of Care, Inc. Ellagsäureformulierungen zur verwendung bei gerinnungstests
CN106999930B (zh) 2014-09-26 2020-09-08 雅培医护站股份有限公司 用于测定流体样本中的凝结的具有分段射流的盒设备
EP3954457A3 (de) * 2014-09-26 2022-05-18 Abbott Point Of Care Inc Mikrohergestellte vorrichtung mit mikroumgebungssensoren zur prüfung der koagulation in fluidproben
CN107107056B (zh) 2014-09-26 2020-04-14 雅培医护站股份有限公司 用于流体样本中的凝结测定的单通道盒设备
CN106093440A (zh) * 2016-06-06 2016-11-09 中国人民解放军总医院 一种用于检测人体血液凝集功能的诊断试剂及其制备方法与使用方法
JP6873833B2 (ja) * 2017-06-09 2021-05-19 シスメックス株式会社 血液検体の判定方法、血液検体分析装置及びコンピュータプログラム
CN108152517A (zh) * 2017-12-27 2018-06-12 北京乐普医疗科技有限责任公司 一种测试活化部分凝血活酶时间的装置和方法
CN111638375B (zh) * 2020-06-08 2022-12-13 深圳市国赛生物技术有限公司 一种用于测定活化部分凝血活酶时间的体外诊断试剂盒
AU2022341032A1 (en) * 2021-09-06 2024-04-11 Haemograph Pty Ltd Reagent pre-loading system and measuring device

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3550581A (en) * 1966-10-14 1970-12-29 Edwin Boyle Jr Apparatus and method for determining the tendency to thrombose
US3951606A (en) * 1974-05-17 1976-04-20 Geomet, Inc. Apparatus for prothrombin testing
US3969079A (en) * 1975-01-08 1976-07-13 Alphamedics Mfg. Corporation Dual channel photo-optical clot detection apparatus
DE3407280A1 (de) * 1984-02-28 1985-09-19 Gödecke AG, 1000 Berlin Testsatz zur bestimmung der aktivierten partiellen thromboplastinzeit (ptt) mit erhoehter heparinempfindlichkeit
US4756884A (en) * 1985-08-05 1988-07-12 Biotrack, Inc. Capillary flow device
US4761381A (en) * 1985-09-18 1988-08-02 Miles Inc. Volume metering capillary gap device for applying a liquid sample onto a reactive surface
DE3541057A1 (de) * 1985-11-19 1987-05-21 Kratzer Michael Verfahren und einrichtung zur messung der aggregation der blutplaettchen bzw. der koagulation des blutes
US4755461A (en) * 1986-04-17 1988-07-05 Bio/Data Corporation Tableted blood plasma microconcentrated thromboplastin coagulation reagent
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
AU617418B2 (en) * 1988-01-14 1991-11-28 Novo Nordisk A/S Apparatus for determination of the coagulation time of a blood sample

Also Published As

Publication number Publication date
EP0394070A1 (de) 1990-10-24
JPH0751078B2 (ja) 1995-06-05
EP0394070B1 (de) 1994-09-07
JPH03503722A (ja) 1991-08-22
US5039617A (en) 1991-08-13
AU622541B2 (en) 1992-04-09
AU5374690A (en) 1990-10-25
DE69012195D1 (de) 1994-10-13
ES2071764T3 (es) 1995-07-01
DE69012195T2 (de) 1995-03-02
WO1990013034A1 (en) 1990-11-01
CA1334928C (en) 1995-03-28

Similar Documents

Publication Publication Date Title
ATE111224T1 (de) Kapillare durchflussvorrichtung und verfahren zur messung der aktivierten partiellen thromboplastinzeit.
EP0417305A4 (en) Analyzer of liquid sample and analyzing method of liquid sample using said analyzer
DE60112017D1 (de) Verfahren, Reagenz, Messkartusche und Vorrichtung zur Fibrinogenbestimmung
SE7510863L (sv) Anordning for sampling, blandade av samplet med ett reagensmedel samt utforande av serskilt optisk analys
DE3853457T2 (de) Vorrichtung und verfahren zur genauen, schnellen und einfachen durchführung eines prothrombin tests.
ATE117436T1 (de) Verfahren und vorrichtung gekennzeichnet durch eine nicht-saugfähige, querfluss-ermöglichende membran.
ATE88814T1 (de) Integriertes immunoassayelement.
DE60034479D1 (de) Vorrichtung und verfahren zum bestimmen der koagulation in flüssigproben
ES2035561T3 (es) Analizador volumetrico de sangre multipunto, automatizado.
DE69515858D1 (de) Probenröhrchen zur Bestimmung der Blutsenkung und ein Detergens zur Verwendung darin
ATE76970T1 (de) Pipetten verwendende vorrichtung zur messung der erythrocytensedimentation.
DK0633473T3 (da) Måling af den aktiverede partielle thromboplastin-tid (APTT) i en reaktion i et enkelt trin
ATE131933T1 (de) Verfahren zur abtrennung und messung von spurbestandteilen
NO903748L (no) Fremgangsmaate ved enzymatisk bestemmelse av analyttkonsentrasjoner.
ATE114822T1 (de) Reagens zum nachweis von bilirubin in urin.
DE69330520D1 (de) Vorrichtung und verfahren zur optischen, hämostatischen blutanalyse
ATE133495T1 (de) Verfahren für direkte chemische bindung des d- dimers aus einer biologischen probe zwecks diagnostik und überwachung von thrombolytischen und hyperkoagulablen zuständen
FI915614A0 (fi) Foerfarande och anordning foer identifiering av markerade mineraloljor.
ATE96847T1 (de) Massanalyse von 3-oxo-5-beta-steroid und reagens dafuer.
ATE184109T1 (de) Indikatorreagenzien zum nachweis oder zur messung von analyten, testsatz, der diese enthält, und verfahren zum nachweis oder zur messung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties