ATE101516T1 - Nifedipin enthaltende oral verabreichbare instant-kapsel. - Google Patents
Nifedipin enthaltende oral verabreichbare instant-kapsel.Info
- Publication number
- ATE101516T1 ATE101516T1 AT88118596T AT88118596T ATE101516T1 AT E101516 T1 ATE101516 T1 AT E101516T1 AT 88118596 T AT88118596 T AT 88118596T AT 88118596 T AT88118596 T AT 88118596T AT E101516 T1 ATE101516 T1 AT E101516T1
- Authority
- AT
- Austria
- Prior art keywords
- solution
- nifedipin
- capsule containing
- oral capsule
- ester component
- Prior art date
Links
- 229940100691 oral capsule Drugs 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 150000002148 esters Chemical class 0.000 abstract 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- 239000002775 capsule Substances 0.000 abstract 2
- HYIMSNHJOBLJNT-UHFFFAOYSA-N nifedipine Chemical compound COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C1=CC=CC=C1[N+]([O-])=O HYIMSNHJOBLJNT-UHFFFAOYSA-N 0.000 abstract 2
- 229960001597 nifedipine Drugs 0.000 abstract 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 229920002690 Polyoxyl 40 HydrogenatedCastorOil Polymers 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 239000004359 castor oil Substances 0.000 abstract 1
- 235000019438 castor oil Nutrition 0.000 abstract 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 229920001515 polyalkylene glycol Polymers 0.000 abstract 1
- -1 polyoxyethylene Polymers 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873738236 DE3738236A1 (de) | 1987-11-11 | 1987-11-11 | Beisskapsel |
| EP88118596A EP0315960B1 (de) | 1987-11-11 | 1988-11-09 | Nifedipin enthaltende Kapsel zur sofortigen oralen Freisetzung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE101516T1 true ATE101516T1 (de) | 1994-03-15 |
Family
ID=6340247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88118596T ATE101516T1 (de) | 1987-11-11 | 1988-11-09 | Nifedipin enthaltende oral verabreichbare instant-kapsel. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5200192A (de) |
| EP (1) | EP0315960B1 (de) |
| JP (1) | JPH01238528A (de) |
| AT (1) | ATE101516T1 (de) |
| AU (1) | AU616693B2 (de) |
| CA (1) | CA1312549C (de) |
| DE (2) | DE3738236A1 (de) |
| ES (1) | ES2061607T3 (de) |
| IE (1) | IE63182B1 (de) |
| ZA (1) | ZA888441B (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3121080B2 (ja) * | 1991-12-19 | 2000-12-25 | アール・ピー・シーラー コーポレイション | カプセル封入用溶液 |
| IT1263840B (it) * | 1993-03-30 | 1996-09-04 | Giuseppe Furiosi | Formulazioni orali di ubidecarenone in forma di capsule |
| GB9325445D0 (en) | 1993-12-13 | 1994-02-16 | Cortecs Ltd | Pharmaceutical formulations |
| AU2190697A (en) * | 1996-04-12 | 1997-11-07 | Flemington Pharmaceutical Corporation | Buccal polar spray or capsule |
| IT1284604B1 (it) * | 1996-09-27 | 1998-05-21 | Roberto Valducci | Composizioni farmaceutiche a rilascio controllato per somministrazione orale contenenti nifedipina come sostanza attiva |
| US20030077227A1 (en) | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating disorders of the central nervous system |
| US7632517B2 (en) | 1997-10-01 | 2009-12-15 | Novadel Pharma Inc. | Buccal, polar and non-polar spray containing zolpidem |
| US20040136914A1 (en) | 1997-10-01 | 2004-07-15 | Dugger Harry A. | Buccal, polar and non-polar spray containing ondansetron |
| AU4894697A (en) | 1997-10-01 | 1999-04-23 | Flemington Pharmaceutical Corporation | Buccal, polar and non-polar spray or capsule |
| US20030185761A1 (en) | 1997-10-01 | 2003-10-02 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating pain |
| US6168806B1 (en) | 1999-03-05 | 2001-01-02 | Fang-Yu Lee | Orally administrable nifedipine pellet and process for the preparation thereof |
| DE19922537A1 (de) * | 1999-05-10 | 2000-11-16 | Roland Bodmeier | Darreichungsform zur Applikation in Körperöffnungen |
| US20040115134A1 (en) * | 1999-06-22 | 2004-06-17 | Elan Pharma International Ltd. | Novel nifedipine compositions |
| SE9902742D0 (sv) * | 1999-07-20 | 1999-07-20 | Astra Ab | New pharmaceutical formultion |
| EP1309318A1 (de) * | 2000-08-17 | 2003-05-14 | Machines Industrielles Etablissements Kirchstrasse | Verbrauchbare behälter |
| US20030003144A1 (en) * | 2001-05-01 | 2003-01-02 | Keller Brian C. | Sustained release formulations for nifedipine, dextromethorphan, and danazol |
| DE10142416A1 (de) * | 2001-08-31 | 2003-03-20 | Molecular And Clinical Drug Re | Verfahren zur Herstellung von Lösungen |
| DE10142417A1 (de) * | 2001-08-31 | 2003-03-20 | Molecular And Clinical Drug Re | Arzneimittel |
| NZ550320A (en) | 2004-04-15 | 2010-02-26 | Chiasma Inc | Compositions capable of facilitating penetration across a biological barrier |
| US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| US7530804B2 (en) * | 2004-12-07 | 2009-05-12 | Mcneil-Ppc, Inc. | System and process for providing at least one opening in dosage forms |
| EP2252262B1 (de) * | 2008-01-18 | 2020-03-18 | Dow Global Technologies LLC | Verfahren zur verbesserung der wasserlöslichkeit von schwer löslichen wirkstoffen mit methoxypolyethylenglykol |
| BRPI0918652B1 (pt) | 2008-09-17 | 2021-10-19 | Chiasma, Inc. | Composição farmacêutica compreendendo um meio hidrofóbico e uma forma sólida que compreende polipeptídeo e sal de ácido graxo de cadeia média, processo de produção da mesma e forma de dosagem oral |
| JP6067687B2 (ja) | 2011-06-08 | 2017-01-25 | エルテーエス ローマン テラピー−ジステーメ アーゲー | 味覚マスキングのためのイオン交換樹脂を含有する可食性経口ストリップ又はウエハース剤形 |
| HUE071943T2 (hu) | 2015-02-03 | 2025-10-28 | Amryt Endo Inc | Akromegália kezelése oktreotid orális alkalmazásával |
| US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU432703A3 (de) * | 1971-08-24 | 1974-06-15 | Фридрих Боссерт, Вульф Фатер, Курт Бауер | |
| DE2209526C3 (de) * | 1972-02-29 | 1980-02-28 | Bayer Ag, 5090 Leverkusen | Coronartherapeutlkum in Form von Gelatine-BeiBkapseln |
| DE3237814A1 (de) * | 1982-10-12 | 1984-04-12 | Warner-Lambert Co., 07950 Morris Plains, N.J. | Wasserfreie emulsionen und verwendung derselben |
| DE3307422A1 (de) * | 1983-03-03 | 1984-09-06 | Bayer Ag, 5090 Leverkusen | Fluessigzubereitungen von dihydropyridinen, ein verfahren zu ihrer herstellung, sowie ihre verwendung bei der bekaempfung von erkrankungen |
| DE3437599C2 (de) * | 1984-10-13 | 1987-04-16 | Dolorgiet GmbH & Co KG, 5205 St Augustin | Ibuprofen enthaltende Weichgelatinekapseln |
| US4689233A (en) * | 1986-01-06 | 1987-08-25 | Siegfried Aktiengesellschaft | Coronary therapeutic agent in the form of soft gelatin capsules |
| SE8601624D0 (sv) * | 1986-04-11 | 1986-04-11 | Haessle Ab | New pharmaceutical preparations |
| GB8629761D0 (en) * | 1986-12-12 | 1987-01-21 | Harris Pharma Ltd | Capsules |
| DE3682208D1 (de) * | 1986-12-18 | 1991-11-28 | Kurt Heinz Bauer | Gegenueber lichteinfluss stabilisiertes nifedipin-konzentrat und verfahren zu seiner herstellung. |
-
1987
- 1987-11-11 DE DE19873738236 patent/DE3738236A1/de not_active Withdrawn
-
1988
- 1988-11-09 EP EP88118596A patent/EP0315960B1/de not_active Revoked
- 1988-11-09 AT AT88118596T patent/ATE101516T1/de not_active IP Right Cessation
- 1988-11-09 ES ES88118596T patent/ES2061607T3/es not_active Expired - Lifetime
- 1988-11-09 DE DE3887826T patent/DE3887826T2/de not_active Revoked
- 1988-11-10 IE IE337888A patent/IE63182B1/en not_active IP Right Cessation
- 1988-11-10 AU AU24993/88A patent/AU616693B2/en not_active Ceased
- 1988-11-11 ZA ZA888441A patent/ZA888441B/xx unknown
- 1988-11-11 JP JP63286611A patent/JPH01238528A/ja active Pending
- 1988-11-14 US US07/270,957 patent/US5200192A/en not_active Expired - Fee Related
- 1988-11-14 CA CA000583042A patent/CA1312549C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE63182B1 (en) | 1995-03-22 |
| DE3887826T2 (de) | 1994-09-22 |
| US5200192A (en) | 1993-04-06 |
| ES2061607T3 (es) | 1994-12-16 |
| JPH01238528A (ja) | 1989-09-22 |
| EP0315960A1 (de) | 1989-05-17 |
| CA1312549C (en) | 1993-01-12 |
| DE3887826D1 (de) | 1994-03-24 |
| EP0315960B1 (de) | 1994-02-16 |
| DE3738236A1 (de) | 1989-05-24 |
| AU2499388A (en) | 1989-05-11 |
| ZA888441B (en) | 1989-08-30 |
| AU616693B2 (en) | 1991-11-07 |
| IE883378L (en) | 1989-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee | ||
| RZN | Patent revoked |