ATA242786A - Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats - Google Patents

Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats

Info

Publication number
ATA242786A
ATA242786A AT0242786A AT242786A ATA242786A AT A242786 A ATA242786 A AT A242786A AT 0242786 A AT0242786 A AT 0242786A AT 242786 A AT242786 A AT 242786A AT A242786 A ATA242786 A AT A242786A
Authority
AT
Austria
Prior art keywords
carboxylats
pyridiniummethyl
cephem
methylethoxy
acetamido
Prior art date
Application number
AT0242786A
Other languages
English (en)
Other versions
AT387779B (de
Inventor
W Dr Veit
K Dr Wessely
Original Assignee
Biochemie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT0242786A priority Critical patent/AT387779B/de
Application filed by Biochemie Gmbh filed Critical Biochemie Gmbh
Priority to KR1019880700504A priority patent/KR950010085B1/ko
Priority to AT87905949T priority patent/ATE74922T1/de
Priority to EP87905949A priority patent/EP0282531B1/de
Priority to JP62505355A priority patent/JP2539872B2/ja
Priority to DE8787905949T priority patent/DE3778346D1/de
Priority to PCT/EP1987/000510 priority patent/WO1988002001A1/de
Publication of ATA242786A publication Critical patent/ATA242786A/de
Application granted granted Critical
Publication of AT387779B publication Critical patent/AT387779B/de
Priority to US07/494,272 priority patent/US5182383A/en
Priority to HK78195A priority patent/HK78195A/xx
Priority to JP8005639A priority patent/JP2572563B2/ja

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
AT0242786A 1986-09-10 1986-09-10 Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats AT387779B (de)

Priority Applications (10)

Application Number Priority Date Filing Date Title
AT0242786A AT387779B (de) 1986-09-10 1986-09-10 Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats
AT87905949T ATE74922T1 (de) 1986-09-10 1987-09-09 Stabile, kristalline form eines cefalosporinzwischenproduktes.
EP87905949A EP0282531B1 (de) 1986-09-10 1987-09-09 Stabile, kristalline form eines cefalosporin-zwischenproduktes
JP62505355A JP2539872B2 (ja) 1986-09-10 1987-09-09 セファロスポリン中間生成物の新規安定な結晶形
KR1019880700504A KR950010085B1 (ko) 1986-09-10 1987-09-09 안정한 결정형태의 세팔로스포린 중간생성물
DE8787905949T DE3778346D1 (de) 1986-09-10 1987-09-09 Stabile, kristalline form eines cefalosporin-zwischenproduktes.
PCT/EP1987/000510 WO1988002001A1 (en) 1986-09-10 1987-09-09 New stable crystalline form of an intermediate product of cephalosporine
US07/494,272 US5182383A (en) 1986-09-10 1990-02-23 Stable, crystalline form of a cephalosporin intermediate product
HK78195A HK78195A (en) 1986-09-10 1995-05-18 Stable crystalline form of an intermediate product of cephalosporine
JP8005639A JP2572563B2 (ja) 1986-09-10 1996-01-17 セファロスポリン中間生成物の新規安定な結晶形

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0242786A AT387779B (de) 1986-09-10 1986-09-10 Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats

Publications (2)

Publication Number Publication Date
ATA242786A true ATA242786A (de) 1988-08-15
AT387779B AT387779B (de) 1989-03-10

Family

ID=3534157

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0242786A AT387779B (de) 1986-09-10 1986-09-10 Verfahren zur herstellung einer neuen kristallinen, stabilen form des syn-isomeren des (6r,7r)-7-((2-(2-amino-4-thiazolyl)-(z)-2-(1-te t.butoxycarbonyl-1-methylethoxy)imino)acetamido -3- (1-pyridiniummethyl)-3-cephem-4-carboxylats

Country Status (1)

Country Link
AT (1) AT387779B (de)

Also Published As

Publication number Publication date
AT387779B (de) 1989-03-10

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