ATE31532T1 - Thiazolderivat, verfahren zu seiner herstellung sowie seine verwendung bei der herstellung von beta-lactam-antibiotika. - Google Patents
Thiazolderivat, verfahren zu seiner herstellung sowie seine verwendung bei der herstellung von beta-lactam-antibiotika.Info
- Publication number
- ATE31532T1 ATE31532T1 AT83302409T AT83302409T ATE31532T1 AT E31532 T1 ATE31532 T1 AT E31532T1 AT 83302409 T AT83302409 T AT 83302409T AT 83302409 T AT83302409 T AT 83302409T AT E31532 T1 ATE31532 T1 AT E31532T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- beta
- lactam antibiotics
- thiazole derivative
- oxyimino
- Prior art date
Links
- 239000003782 beta lactam antibiotic agent Substances 0.000 title abstract 2
- 239000002132 β-lactam antibiotic Substances 0.000 title abstract 2
- 229940124586 β-lactam antibiotics Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 150000007979 thiazole derivatives Chemical class 0.000 title 1
- -1 (Z)-2-(2-aminothiazol-4-yl)-2-(2-carboxyprop-2-oxyimino)acetamido side chain Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- ROUMLFTUNUCTHG-PVLAGJIFSA-N tert-butyl 2-[(z)-[2-chloro-2-oxo-1-[2-(tritylamino)-1,3-thiazol-4-yl]ethylidene]amino]oxy-2-methylpropanoate;hydrochloride Chemical compound Cl.CC(C)(C)OC(=O)C(C)(C)O\N=C(/C(Cl)=O)C1=CSC(NC(C=2C=CC=CC=2)(C=2C=CC=CC=2)C=2C=CC=CC=2)=N1 ROUMLFTUNUCTHG-PVLAGJIFSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8212491 | 1982-04-29 | ||
| EP83302409A EP0101148B1 (de) | 1982-04-29 | 1983-04-28 | Thiazolderivat, Verfahren zu seiner Herstellung sowie seine Verwendung bei der Herstellung von Beta-Lactam-Antibiotika |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE31532T1 true ATE31532T1 (de) | 1988-01-15 |
Family
ID=10530076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83302409T ATE31532T1 (de) | 1982-04-29 | 1983-04-28 | Thiazolderivat, verfahren zu seiner herstellung sowie seine verwendung bei der herstellung von beta-lactam-antibiotika. |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0101148B1 (de) |
| JP (1) | JPS58194871A (de) |
| AT (1) | ATE31532T1 (de) |
| DE (1) | DE3375013D1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0113568B1 (de) * | 1982-12-27 | 1990-04-04 | Eli Lilly And Company | Zwischenverbindungen für die Herstellung von Ceftazidin und Verfahren zu ihrer Herstellung |
| EP0115770B2 (de) * | 1983-01-07 | 1996-06-19 | Takeda Chemical Industries, Ltd. | Thiazolderivate |
| KR100342600B1 (ko) * | 2000-03-06 | 2002-07-04 | 한미정밀화학주식회사 | 신규한 티아졸 화합물 및 그의 제조 방법 |
| KR100392409B1 (ko) * | 2000-03-20 | 2003-07-22 | 한미정밀화학주식회사 | 신규한 티아졸 화합물을 이용한 세팔로스포린계항생물질의 제조 방법 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR229883A1 (es) * | 1978-05-26 | 1983-12-30 | Glaxo Group Ltd | Procedimiento para la preparacion de antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)-acetamido)-3-(1-piridinometil)-cef-3-em-4-carboxilato |
| FR2494280A1 (fr) * | 1980-11-20 | 1982-05-21 | Rhone Poulenc Ind | Nouveaux derives de la cephalosporine et leur preparation |
-
1983
- 1983-04-28 DE DE8383302409T patent/DE3375013D1/de not_active Expired
- 1983-04-28 AT AT83302409T patent/ATE31532T1/de not_active IP Right Cessation
- 1983-04-28 JP JP58074211A patent/JPS58194871A/ja active Pending
- 1983-04-28 EP EP83302409A patent/EP0101148B1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0101148A3 (en) | 1984-12-05 |
| EP0101148B1 (de) | 1987-12-23 |
| DE3375013D1 (en) | 1988-02-04 |
| EP0101148A2 (de) | 1984-02-22 |
| JPS58194871A (ja) | 1983-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |