AT387013B - Verfahren zur herstellung von poly-4-aminopyrrol -2-carboxamidoderivaten - Google Patents

Verfahren zur herstellung von poly-4-aminopyrrol -2-carboxamidoderivaten

Info

Publication number
AT387013B
AT387013B AT0188886A AT188886A AT387013B AT 387013 B AT387013 B AT 387013B AT 0188886 A AT0188886 A AT 0188886A AT 188886 A AT188886 A AT 188886A AT 387013 B AT387013 B AT 387013B
Authority
AT
Austria
Prior art keywords
aminopyrrol
producing poly
carboxamido derivatives
carboxamido
derivatives
Prior art date
Application number
AT0188886A
Other languages
German (de)
English (en)
Other versions
ATA188886A (de
Inventor
Federico Arcamone
Nicola Mongelli
Sergio Penco
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858517922A external-priority patent/GB8517922D0/en
Priority claimed from GB868613594A external-priority patent/GB8613594D0/en
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of ATA188886A publication Critical patent/ATA188886A/de
Application granted granted Critical
Publication of AT387013B publication Critical patent/AT387013B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyamides (AREA)
AT0188886A 1985-07-16 1986-07-11 Verfahren zur herstellung von poly-4-aminopyrrol -2-carboxamidoderivaten AT387013B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858517922A GB8517922D0 (en) 1985-07-16 1985-07-16 Carboxamido derivatives
GB868613594A GB8613594D0 (en) 1986-06-04 1986-06-04 Poly-4-aminopyrrole-2-carboxamido derivatives

Publications (2)

Publication Number Publication Date
ATA188886A ATA188886A (de) 1988-04-15
AT387013B true AT387013B (de) 1988-11-25

Family

ID=26289538

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0188886A AT387013B (de) 1985-07-16 1986-07-11 Verfahren zur herstellung von poly-4-aminopyrrol -2-carboxamidoderivaten

Country Status (26)

Country Link
JP (1) JPH0780843B2 (zh)
KR (1) KR930010496B1 (zh)
CN (1) CN1018825B (zh)
AT (1) AT387013B (zh)
AU (1) AU587841B2 (zh)
BE (1) BE905110A (zh)
CA (1) CA1285934C (zh)
CH (1) CH674206A5 (zh)
CS (1) CS276981B6 (zh)
DE (1) DE3623880A1 (zh)
DK (1) DK335986A (zh)
ES (1) ES2000502A6 (zh)
FI (1) FI83640C (zh)
FR (1) FR2585018B1 (zh)
GB (1) GB2178036B (zh)
GR (1) GR861841B (zh)
HU (1) HU205949B (zh)
IE (1) IE59073B1 (zh)
IL (1) IL79402A (zh)
IT (1) IT1196488B (zh)
NL (1) NL8601837A (zh)
NO (1) NO168826C (zh)
NZ (1) NZ216829A (zh)
PH (1) PH24714A (zh)
PT (1) PT82984B (zh)
SE (1) SE468642B (zh)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN85103908A (zh) * 1985-07-16 1986-11-05 法米塔利·卡洛·埃尔巴有限公司 制备4′-表多克索红菌素的新方法
GB8906709D0 (en) * 1989-03-23 1989-05-10 Creighton Andrew M Acryloyl substituted pyrrole derivatives
IT1243389B (it) * 1990-11-22 1994-06-10 Menarini Farma Ind Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono.
AU1224392A (en) * 1991-02-06 1992-09-07 Synphar Laboratories, Inc. Oligopeptide antiretroviral agents
IT1247878B (it) * 1991-02-15 1995-01-05 Menarini Farma Ind Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono
GB2260134A (en) * 1991-10-04 1993-04-07 Erba Carlo Spa Derivatives of poly-5-amino-3-carboxy-1-methyl compounds
IT1262921B (it) * 1992-01-10 1996-07-22 Federico Arcamone Agenti antitumorali analoghi di oligopeptidi pirrol-amidinici retroversi processi di preparazione e prodotti farmaceutici che li contengono
GB9416005D0 (en) * 1994-08-08 1994-09-28 Erba Carlo Spa Peptidic compounds analogous to distamycin a and process for their preparation
AU6943796A (en) * 1995-09-12 1997-04-01 Kyowa Hakko Kogyo Co. Ltd. Compounds UCH 15
AU1596097A (en) * 1996-02-02 1997-08-22 Pharmacia & Upjohn S.P.A. Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB9615692D0 (en) * 1996-07-25 1996-09-04 Pharmacia Spa Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
GB0011059D0 (en) 2000-05-08 2000-06-28 Pharmacia & Upjohn Spa Use of substituted acryloyl distamycin derivatives in the treatment of tumours associated with high levels of glutathione
GB0015447D0 (en) 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl derivates and alkylating agents
GB0015446D0 (en) 2000-06-23 2000-08-16 Pharmacia & Upjohn Spa Combined therapy against tumors comprising substituted acryloyl distamycin derivates,taxanes and/or antimetabolites
GB0016447D0 (en) 2000-07-04 2000-08-23 Pharmacia & Upjohn Spa Process for preparing distamycin derivatives
US6969592B2 (en) 2001-09-26 2005-11-29 Pharmacia Italia S.P.A. Method for predicting the sensitivity to chemotherapy

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470284B1 (de) * 1963-07-26 1971-12-16 Farmaceutici Italia Beta-{1-Methyl-4-[1-methyl-4-(1-methyl-4-formylamino-pyrrol-2-carboxamido)-pyrrol-2-carboxamido]-pyrrol-2-carboxamido}-propionamidin sowie dessen Saeureadditionssalze
DE1795539A1 (de) * 1963-07-26 1972-01-13 Farmaceutici Italia Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen
DE1620286B1 (de) * 1964-07-14 1974-02-21 Farmaceutici Italia Verfahren zur Herstellung von Pyrrolderivaten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR86210E (zh) 1963-04-04 1966-03-23
BE666612A (zh) * 1963-07-26 1965-11-03
CN85103908A (zh) * 1985-07-16 1986-11-05 法米塔利·卡洛·埃尔巴有限公司 制备4′-表多克索红菌素的新方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1470284B1 (de) * 1963-07-26 1971-12-16 Farmaceutici Italia Beta-{1-Methyl-4-[1-methyl-4-(1-methyl-4-formylamino-pyrrol-2-carboxamido)-pyrrol-2-carboxamido]-pyrrol-2-carboxamido}-propionamidin sowie dessen Saeureadditionssalze
DE1795539A1 (de) * 1963-07-26 1972-01-13 Farmaceutici Italia Verfahren zur Herstellung von neuen Pyrrolderivaten und ihren Salzen
DE1620286B1 (de) * 1964-07-14 1974-02-21 Farmaceutici Italia Verfahren zur Herstellung von Pyrrolderivaten

Also Published As

Publication number Publication date
IE59073B1 (en) 1994-01-12
FI862959A (fi) 1987-01-17
FI83640B (fi) 1991-04-30
DK335986A (da) 1987-01-17
KR930010496B1 (ko) 1993-10-25
DK335986D0 (da) 1986-07-15
IT8621125A1 (it) 1988-01-15
IT1196488B (it) 1988-11-16
IE861875L (en) 1987-01-16
AU6020286A (en) 1987-01-22
NZ216829A (en) 1989-03-29
PT82984A (en) 1986-08-01
JPS6277362A (ja) 1987-04-09
PH24714A (en) 1990-10-01
CN86104787A (zh) 1987-02-18
SE8603098L (sv) 1987-01-17
NL8601837A (nl) 1987-02-16
ES2000502A6 (es) 1988-03-01
NO168826B (no) 1991-12-30
FI862959A0 (fi) 1986-07-16
AU587841B2 (en) 1989-08-31
NO168826C (no) 1992-04-08
NO862860L (no) 1987-01-19
FR2585018A1 (fr) 1987-01-23
CS276981B6 (en) 1992-11-18
PT82984B (pt) 1989-01-30
IT8621125A0 (it) 1986-07-15
BE905110A (fr) 1987-01-15
FR2585018B1 (fr) 1989-07-13
SE468642B (sv) 1993-02-22
CN1018825B (zh) 1992-10-28
SE8603098D0 (sv) 1986-07-11
CH674206A5 (zh) 1990-05-15
FI83640C (fi) 1991-08-12
IL79402A0 (en) 1986-10-31
DE3623880A1 (de) 1987-01-29
GB8617292D0 (en) 1986-08-20
GR861841B (en) 1986-11-18
KR870001201A (ko) 1987-03-12
GB2178036A (en) 1987-02-04
JPH0780843B2 (ja) 1995-08-30
NO862860D0 (no) 1986-07-15
HUT43088A (en) 1987-09-28
CS8605412A2 (en) 1991-03-12
IL79402A (en) 1991-06-10
HU205949B (en) 1992-07-28
GB2178036B (en) 1989-08-16
ATA188886A (de) 1988-04-15
CA1285934C (en) 1991-07-09

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Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee
UEP Publication of translation of european patent specification