AT379590B - Verfahren zur herstellung von neuen 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridinderivaten - Google Patents

Verfahren zur herstellung von neuen 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridinderivaten

Info

Publication number
AT379590B
AT379590B AT0096882A AT96882A AT379590B AT 379590 B AT379590 B AT 379590B AT 0096882 A AT0096882 A AT 0096882A AT 96882 A AT96882 A AT 96882A AT 379590 B AT379590 B AT 379590B
Authority
AT
Austria
Prior art keywords
trifluormethylphenyl
producing new
tetrahydropyridine derivatives
tetrahydropyridine
derivatives
Prior art date
Application number
AT0096882A
Other languages
English (en)
Other versions
ATA96882A (de
Inventor
Dino Nisato
Alberto Bianchetti
Artemio Pessa
Paolo Carminati
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ATA96882A publication Critical patent/ATA96882A/de
Application granted granted Critical
Publication of AT379590B publication Critical patent/AT379590B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT0096882A 1981-03-11 1982-03-11 Verfahren zur herstellung von neuen 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridinderivaten AT379590B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8104891A FR2501506A1 (fr) 1981-03-11 1981-03-11 Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine

Publications (2)

Publication Number Publication Date
ATA96882A ATA96882A (de) 1985-06-15
AT379590B true AT379590B (de) 1986-01-27

Family

ID=9256121

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0096882A AT379590B (de) 1981-03-11 1982-03-11 Verfahren zur herstellung von neuen 4-(3-trifluormethylphenyl)-1,2,3,6-tetrahydropyridinderivaten

Country Status (8)

Country Link
EP (1) EP0060179A1 (de)
JP (1) JPS57159714A (de)
AT (1) AT379590B (de)
AU (1) AU8111282A (de)
FR (1) FR2501506A1 (de)
IL (1) IL65170A0 (de)
NZ (1) NZ199974A (de)
ZA (1) ZA821519B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531707A1 (fr) * 1982-08-16 1984-02-17 Midy Spa Trifluoromethylphenyltetrahydropyridines substituees a activite anorexigene, un procede de preparation et compositions pharmaceutiques
DE3438394A1 (de) * 1984-10-19 1986-04-30 Merck Patent Gmbh, 6100 Darmstadt Pyridinderivate
JPH0269125U (de) * 1988-11-14 1990-05-25
FR2639226B1 (fr) * 1988-11-18 1993-11-05 Sanofi Utilisation de trifluoromethylphenyltetrahydropyridines pour la preparation de medicaments destines a combattre les troubles anxio-depressifs
SE9904723D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission II
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
SE9904724D0 (sv) * 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
SE0401465D0 (sv) 2004-06-08 2004-06-08 Carlsson A Research Ab New substituted piperdines as modulators of dopamine neurotransmission
US7851629B2 (en) 2004-06-08 2010-12-14 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
DE602005017784D1 (de) 2004-06-08 2009-12-31 Nsab, Filial Af Neurosearch Sweden Ab Neue disubstituierte phenylpiperidine als modulatoren der dopamin- und serotoninneurotransmission
EP1802573B1 (de) 2004-10-13 2016-09-28 Teva Pharmaceuticals International GmbH Verfahren zur herstellung von 4-(3-methansulfonylphenyl)-1-n-propylpiperidin
SE529246C2 (sv) 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
US9012476B2 (en) 2011-12-08 2015-04-21 IVAX International GmbH Hydrobromide salt of pridopidine
EA027748B1 (ru) 2012-04-04 2017-08-31 Тева Фармасьютикалз Интернэшнл Гмбх Применение придопидина в комбинации с тетрабеназином для лечения двигательных нарушений и ожирения

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3284457A (en) * 1964-01-17 1966-11-08 Degussa 1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
DE1814342A1 (de) * 1967-12-13 1969-10-23 Robins Co Inc A H Derivate von Arylpyridinylalkoholen und Verfahren zu deren Herstellung

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125488A (en) * 1964-03-17 Method of inducing analgesia by
US2498431A (en) * 1945-06-13 1950-02-21 Hoffmann La Roche 2-and 4-homocyclyl substituted piperidines
GB881894A (en) * 1958-04-22 1961-11-08 Paul Adriaan Jan Janssen Tetrahydropyridine derivatives
FR86403E (fr) * 1959-05-01 1966-02-04 May & Baker Ltd Nouveaux dérivés de la phényl-4 pipéridine et leur préparation
FR1459013A (fr) * 1964-08-05 1966-04-29 Allen & Hanburys Ltd Procédé de préparation de dérivés de la 4-phényl-pipéridine
BE757436A (fr) * 1969-10-27 1971-03-16 Robins Co Inc A H 1-carbamoyl-4-phenyl-piperidines et -tetrahydropyridines, leur procede de preparation et leurs applications comme anticonvulsivants et relaxants musculaires
US3833576A (en) * 1970-06-17 1974-09-03 Hoffmann La Roche Process for the preparation of aromatic ethers and intermediates useful therefor
DE2101997A1 (en) * 1971-01-16 1972-08-03 Farbenfabriken Bayer AG, 509öfLeverkusen 1-benzyl-4-subst-tetrahydropyridines - useful as intermediates for pharmaceuticals
FR2340734A1 (fr) * 1976-02-13 1977-09-09 Roussel Uclaf Nouveaux derives de la m-trifluoromethylphenyl piperidine et leurs sels, procede de preparation et application a titre de medicaments
FR2416886A1 (fr) * 1978-02-08 1979-09-07 Roussel Uclaf Nouveaux derives de la 3-phenyl-tetrahydropyridine et leurs sels, procedes de preparation et application a titre de medicaments

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3284457A (en) * 1964-01-17 1966-11-08 Degussa 1-lower alkyl-4-substituted phenyl-1, 2, 3, 6-tetrahydropyridines and acid addition salts
DE1814342A1 (de) * 1967-12-13 1969-10-23 Robins Co Inc A H Derivate von Arylpyridinylalkoholen und Verfahren zu deren Herstellung

Also Published As

Publication number Publication date
IL65170A0 (en) 1982-05-31
FR2501506A1 (fr) 1982-09-17
NZ199974A (en) 1985-05-31
AU8111282A (en) 1982-09-16
ZA821519B (en) 1983-01-26
EP0060179A1 (de) 1982-09-15
FR2501506B1 (de) 1984-07-20
ATA96882A (de) 1985-06-15
JPS57159714A (en) 1982-10-01

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties