AT358044B - Verfahren zur herstellung von mefloquin - Google Patents
Verfahren zur herstellung von mefloquinInfo
- Publication number
- AT358044B AT358044B AT113378A AT113378A AT358044B AT 358044 B AT358044 B AT 358044B AT 113378 A AT113378 A AT 113378A AT 113378 A AT113378 A AT 113378A AT 358044 B AT358044 B AT 358044B
- Authority
- AT
- Austria
- Prior art keywords
- mefloquin
- producing
- producing mefloquin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76981677A | 1977-02-17 | 1977-02-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA113378A ATA113378A (de) | 1980-01-15 |
| AT358044B true AT358044B (de) | 1980-08-11 |
Family
ID=25086585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT113378A AT358044B (de) | 1977-02-17 | 1978-02-16 | Verfahren zur herstellung von mefloquin |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS53103478A (es) |
| AT (1) | AT358044B (es) |
| BE (1) | BE864002A (es) |
| CH (2) | CH640530A5 (es) |
| DE (1) | DE2806909A1 (es) |
| FR (1) | FR2381044A1 (es) |
| GB (1) | GB1594282A (es) |
| IT (1) | IT1158450B (es) |
| NL (1) | NL7801787A (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2940443A1 (de) * | 1979-10-05 | 1981-04-16 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von erythro-(alpha)-2-piperidyl-2,8-bis-(trifluormethyl)-4-chinolin-methanol |
| FR2485014A1 (fr) * | 1980-06-20 | 1981-12-24 | Pharmindustrie | Nouveaux derives de (quinolyl-2, -3 ou -4)-1 (piperidyl ou pyrrolidinyl-2 ou -3)-2 ou -3 ethanone ou propanone, procedes pour leur preparation, et leur utilisation comme medicaments |
| US4507482A (en) * | 1982-04-14 | 1985-03-26 | Hoffmann-La Roche Inc. | Purification of mefloquin hydrochloride |
| DK160499C (da) * | 1982-09-10 | 1991-08-26 | Hoffmann La Roche | Fremgangsmaade til fremstilling af mefloquin og mellemprodukt til anvendelse herved |
| JPH0234129U (es) * | 1989-05-25 | 1990-03-05 | ||
| HUT54363A (en) * | 1989-07-25 | 1991-02-28 | Alkaloida Vegyeszeti Gyar | Process for producing pyridyl-methyl-quinolin derivatives |
| GB9819382D0 (en) * | 1998-09-04 | 1998-10-28 | Cerebrus Ltd | Chemical compounds I |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH590275A5 (es) * | 1970-03-16 | 1977-07-29 | Hoffmann La Roche | |
| CH605916A5 (es) * | 1973-12-07 | 1978-10-13 | Hoffmann La Roche |
-
1978
- 1978-02-15 FR FR7804271A patent/FR2381044A1/fr active Granted
- 1978-02-16 CH CH169578A patent/CH640530A5/de not_active IP Right Cessation
- 1978-02-16 BE BE185206A patent/BE864002A/xx not_active IP Right Cessation
- 1978-02-16 GB GB6207/78A patent/GB1594282A/en not_active Expired
- 1978-02-16 JP JP1601378A patent/JPS53103478A/ja active Granted
- 1978-02-16 AT AT113378A patent/AT358044B/de not_active IP Right Cessation
- 1978-02-16 IT IT20331/78A patent/IT1158450B/it active
- 1978-02-16 NL NL7801787A patent/NL7801787A/xx not_active Application Discontinuation
- 1978-02-17 DE DE19782806909 patent/DE2806909A1/de active Granted
-
1982
- 1982-05-14 CH CH301282A patent/CH640531A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6257631B2 (es) | 1987-12-02 |
| DE2806909A1 (de) | 1978-08-24 |
| JPS53103478A (en) | 1978-09-08 |
| CH640531A5 (en) | 1984-01-13 |
| IT7820331A0 (it) | 1978-02-16 |
| GB1594282A (en) | 1981-07-30 |
| NL7801787A (nl) | 1978-08-21 |
| FR2381044B1 (es) | 1983-06-10 |
| DE2806909C2 (es) | 1988-04-07 |
| FR2381044A1 (fr) | 1978-09-15 |
| BE864002A (fr) | 1978-08-16 |
| ATA113378A (de) | 1980-01-15 |
| IT1158450B (it) | 1987-02-18 |
| CH640530A5 (en) | 1984-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |