AT358044B - METHOD FOR PRODUCING MEFLOQUIN - Google Patents

METHOD FOR PRODUCING MEFLOQUIN

Info

Publication number
AT358044B
AT358044B AT113378A AT113378A AT358044B AT 358044 B AT358044 B AT 358044B AT 113378 A AT113378 A AT 113378A AT 113378 A AT113378 A AT 113378A AT 358044 B AT358044 B AT 358044B
Authority
AT
Austria
Prior art keywords
mefloquin
producing
producing mefloquin
Prior art date
Application number
AT113378A
Other languages
German (de)
Other versions
ATA113378A (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of ATA113378A publication Critical patent/ATA113378A/en
Application granted granted Critical
Publication of AT358044B publication Critical patent/AT358044B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • C07D215/22Oxygen atoms attached in position 2 or 4
    • C07D215/233Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/18Halogen atoms or nitro radicals
AT113378A 1977-02-17 1978-02-16 METHOD FOR PRODUCING MEFLOQUIN AT358044B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76981677A 1977-02-17 1977-02-17

Publications (2)

Publication Number Publication Date
ATA113378A ATA113378A (en) 1980-01-15
AT358044B true AT358044B (en) 1980-08-11

Family

ID=25086585

Family Applications (1)

Application Number Title Priority Date Filing Date
AT113378A AT358044B (en) 1977-02-17 1978-02-16 METHOD FOR PRODUCING MEFLOQUIN

Country Status (9)

Country Link
JP (1) JPS53103478A (en)
AT (1) AT358044B (en)
BE (1) BE864002A (en)
CH (2) CH640530A5 (en)
DE (1) DE2806909A1 (en)
FR (1) FR2381044A1 (en)
GB (1) GB1594282A (en)
IT (1) IT1158450B (en)
NL (1) NL7801787A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2940443A1 (en) * 1979-10-05 1981-04-16 Basf Ag, 6700 Ludwigshafen METHOD FOR PRODUCING ERYTHRO- (ALPHA) -2-PIPERIDYL-2,8-BIS- (TRIFLUORMETHYL) -4-QUINOLINE-METHANOL
FR2485014A1 (en) * 1980-06-20 1981-12-24 Pharmindustrie NOVEL DERIVATIVES OF (QUINOLYL-2, -3 OR -4) -1 (PIPERIDYL OR PYRROLIDINYL-2 OR -3) -2 OR -3 ETHANONE OR PROPANONE, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS
US4507482A (en) * 1982-04-14 1985-03-26 Hoffmann-La Roche Inc. Purification of mefloquin hydrochloride
DK160499C (en) * 1982-09-10 1991-08-26 Hoffmann La Roche PROCEDURE FOR MANUFACTURING MEFLOQUIN AND INTERMEDIATE FOR USE THEREOF
JPH0234129U (en) * 1989-05-25 1990-03-05
HUT54363A (en) * 1989-07-25 1991-02-28 Alkaloida Vegyeszeti Gyar Process for producing pyridyl-methyl-quinolin derivatives
GB9819382D0 (en) * 1998-09-04 1998-10-28 Cerebrus Ltd Chemical compounds I

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH590275A5 (en) * 1970-03-16 1977-07-29 Hoffmann La Roche
CH605916A5 (en) * 1973-12-07 1978-10-13 Hoffmann La Roche

Also Published As

Publication number Publication date
GB1594282A (en) 1981-07-30
NL7801787A (en) 1978-08-21
BE864002A (en) 1978-08-16
CH640531A5 (en) 1984-01-13
IT1158450B (en) 1987-02-18
FR2381044A1 (en) 1978-09-15
IT7820331A0 (en) 1978-02-16
CH640530A5 (en) 1984-01-13
JPS6257631B2 (en) 1987-12-02
DE2806909C2 (en) 1988-04-07
DE2806909A1 (en) 1978-08-24
ATA113378A (en) 1980-01-15
JPS53103478A (en) 1978-09-08
FR2381044B1 (en) 1983-06-10

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties