AT345457B - Verfahren zur herstellung von neuen glycosidverbindungen - Google Patents
Verfahren zur herstellung von neuen glycosidverbindungenInfo
- Publication number
- AT345457B AT345457B AT302676A AT302676A AT345457B AT 345457 B AT345457 B AT 345457B AT 302676 A AT302676 A AT 302676A AT 302676 A AT302676 A AT 302676A AT 345457 B AT345457 B AT 345457B
- Authority
- AT
- Austria
- Prior art keywords
- producing new
- glycoside compounds
- new glycoside
- compounds
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- G—PHYSICS
- G04—HOROLOGY
- G04B—MECHANICALLY-DRIVEN CLOCKS OR WATCHES; MECHANICAL PARTS OF CLOCKS OR WATCHES IN GENERAL; TIME PIECES USING THE POSITION OF THE SUN, MOON OR STARS
- G04B37/00—Cases
- G04B37/0008—Cases for pocket watches and wrist watches
- G04B37/0025—Cases for pocket watches and wrist watches with cover or bottom with a spring (savonette) bench watches opening or closing with spring action G04B37/0463
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB18098/75A GB1506200A (en) | 1975-04-30 | 1975-04-30 | Glycosides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA302676A ATA302676A (de) | 1978-01-15 |
| AT345457B true AT345457B (de) | 1978-09-25 |
Family
ID=10106621
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT302676A AT345457B (de) | 1975-04-30 | 1976-04-26 | Verfahren zur herstellung von neuen glycosidverbindungen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4112076A (de) |
| JP (1) | JPS51133262A (de) |
| AT (1) | AT345457B (de) |
| AU (1) | AU500439B2 (de) |
| BE (1) | BE841266A (de) |
| CA (1) | CA1061335A (de) |
| CH (1) | CH624125A (de) |
| DE (1) | DE2618822C3 (de) |
| DK (1) | DK150203C (de) |
| ES (1) | ES447433A1 (de) |
| FR (1) | FR2309234A1 (de) |
| GB (1) | GB1506200A (de) |
| NL (1) | NL179587C (de) |
| SE (2) | SE431875B (de) |
| SU (1) | SU728719A3 (de) |
| ZA (1) | ZA762562B (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2374333A1 (fr) * | 1976-12-20 | 1978-07-13 | Inst Int Pathologie Cellulaire | Nouveaux derives du naphtacene, leur preparation et les compositions qui les contiennent |
| GB1550879A (en) * | 1976-12-22 | 1979-08-22 | Farmaceutici Italia | Antitumour glycosides |
| GB1567392A (en) * | 1977-02-22 | 1980-05-14 | Farmaceutici Italia | Daunorubicin derivatives |
| US4201773A (en) * | 1978-07-26 | 1980-05-06 | The United States Of America As Represented By The Department Of Health, Education And Welfare | 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone |
| IT1196402B (it) * | 1978-11-21 | 1988-11-16 | Erba Farmitalia | Antibiotici antitumorali |
| NL8001417A (nl) * | 1979-03-17 | 1980-09-19 | Erba Farmitalia | Antitumorglycosiden. |
| JPS5673039A (en) * | 1979-08-20 | 1981-06-17 | Hoffmann La Roche | Naphthacene derivative |
| EP0024727B1 (de) * | 1979-09-01 | 1982-05-26 | FARMITALIA CARLO ERBA S.p.A. | Anthracyclin-Glycoside, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzung |
| US4345068A (en) * | 1979-11-22 | 1982-08-17 | Farmitalia Carlo Erba S.P.A. | Process for the preparation of 4'-epidaunorubicin, 3',4'-diepidaunorubicin, their doxorubicin analogs, and intermediates used in said process |
| US4301276A (en) * | 1980-03-07 | 1981-11-17 | Purdue University | Synthesis of daunosamine hydrochloride and intermediates used in its preparation |
| US4298726A (en) * | 1980-03-07 | 1981-11-03 | Purdue University | Synthesis of N-benzoyl-L-ristosamine and intermediates used in its preparation |
| US4345070A (en) * | 1980-09-29 | 1982-08-17 | Farmitalia Carlo Erba S.P.A. | Process for the preparation of 4'-deoxy-daunorubicin and 4'-deoxy-doxorubicin |
| US5138042A (en) * | 1981-05-28 | 1992-08-11 | Farmitalia Carlo Erba S.P.A. | 6-deoxyanthracyclines |
| NL8203548A (nl) * | 1981-09-18 | 1983-04-18 | Erba Farmitalia | 3'-desamino-analoga van glycoside-antracycline-antibiotica, werkwijze voor hun bereiding, preparaten en gebruik daarvan. |
| GB8426672D0 (en) * | 1984-10-22 | 1984-11-28 | Erba Farmitalia | Pharmaceutical compositions |
| GB2196626B (en) * | 1986-10-15 | 1990-09-19 | Erba Farmitalia | Antitumor anthracycline glycosides, their preparation, intermediates thereof, and compositions and use therefor |
| DE3641835A1 (de) * | 1986-12-08 | 1988-06-16 | Behringwerke Ag | Zytostatisch wirksame anthracyclinderivate |
| GB8803076D0 (en) * | 1988-02-10 | 1988-03-09 | Erba Carlo Spa | 3'-deamino-4'-deoxy-4'-amino anthracyclines |
| GB9216962D0 (en) * | 1992-08-11 | 1992-09-23 | Erba Carlo Spa | Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives |
| US20090099346A1 (en) * | 2003-07-02 | 2009-04-16 | Victor Matvienko | Thermally stable crystalline epirubicin hydrochloride |
| US7485707B2 (en) * | 2003-07-02 | 2009-02-03 | Solux Corporation | Thermally stable crystalline epirubicin hydrochloride and method of making the same |
| US7388083B2 (en) * | 2005-03-07 | 2008-06-17 | Solux Corporation | Epimerization of 4′-C bond and modification of 14-CH3-(CO)-fragment in anthracyclin antibiotics |
| CN101331147B (zh) * | 2005-12-13 | 2011-11-30 | 苏洛克股份有限公司 | 用于制备4-脱甲基柔红霉素的方法 |
| US8802830B2 (en) * | 2005-12-20 | 2014-08-12 | Solux Corporation | Synthesis of epirubicin from 13-dihydrodaunorubicine |
| US8357785B2 (en) * | 2008-01-08 | 2013-01-22 | Solux Corporation | Method of aralkylation of 4′-hydroxyl group of anthracylins |
| EP2301943B1 (de) | 2009-09-08 | 2014-01-08 | Heraeus Precious Metals GmbH & Co. KG | Kristallisierung von Epidaunorubicin x HCI |
| DE102011103751A1 (de) | 2011-05-31 | 2012-12-06 | Heraeus Precious Metals Gmbh & Co. Kg | Kristallisierung von Epirubicinhydrochlorid |
| DE102011111991A1 (de) * | 2011-08-30 | 2013-02-28 | Lead Discovery Center Gmbh | Neue Cyclosporin-Derivate |
| CN103204888B (zh) * | 2012-01-15 | 2016-08-17 | 山东新时代药业有限公司 | 一种盐酸表柔比星中间体的制备方法 |
| US10301343B2 (en) | 2015-03-30 | 2019-05-28 | Meiji Seika Pharma Co., Ltd. | Method of producing epirubicin and novel production intermediate thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3803124A (en) * | 1968-04-12 | 1974-04-09 | Farmaceutici It Soc | Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives |
| GB1467383A (en) * | 1974-06-12 | 1977-03-16 | Farmaceutici Italia | Daunomycin analogues |
| GB1470860A (en) * | 1974-10-29 | 1977-04-21 | Farmaceutici Italia | Anthracycline glycosides |
-
1975
- 1975-04-30 GB GB18098/75A patent/GB1506200A/en not_active Expired
-
1976
- 1976-04-09 US US05/675,696 patent/US4112076A/en not_active Expired - Lifetime
- 1976-04-15 NL NLAANVRAGE7604049,A patent/NL179587C/xx not_active IP Right Cessation
- 1976-04-26 SU SU762353457A patent/SU728719A3/ru active
- 1976-04-26 AT AT302676A patent/AT345457B/de not_active IP Right Cessation
- 1976-04-27 AU AU13390/76A patent/AU500439B2/en not_active Expired
- 1976-04-28 SE SE7604908A patent/SE431875B/xx not_active IP Right Cessation
- 1976-04-28 ZA ZA762562A patent/ZA762562B/xx unknown
- 1976-04-28 DK DK189676A patent/DK150203C/da not_active IP Right Cessation
- 1976-04-28 JP JP51049308A patent/JPS51133262A/ja active Granted
- 1976-04-29 BE BE166557A patent/BE841266A/xx not_active IP Right Cessation
- 1976-04-29 DE DE2618822A patent/DE2618822C3/de not_active Expired
- 1976-04-29 FR FR7612701A patent/FR2309234A1/fr active Granted
- 1976-04-29 ES ES447433A patent/ES447433A1/es not_active Expired
- 1976-04-29 CH CH541176A patent/CH624125A/de not_active IP Right Cessation
- 1976-04-30 CA CA251,514A patent/CA1061335A/en not_active Expired
-
1980
- 1980-02-29 SE SE8001615A patent/SE436884B/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK150203B (da) | 1987-01-05 |
| SE8001615L (sv) | 1980-02-29 |
| GB1506200A (en) | 1978-04-05 |
| US4112076A (en) | 1978-09-05 |
| SE436884B (sv) | 1985-01-28 |
| JPS5619878B2 (de) | 1981-05-09 |
| DE2618822A1 (de) | 1976-11-11 |
| DK150203C (da) | 1987-11-02 |
| DE2618822C3 (de) | 1983-04-28 |
| CH541176A4 (de) | 1981-07-15 |
| CH624125A (de) | 1981-07-15 |
| FR2309234A1 (fr) | 1976-11-26 |
| DK189676A (da) | 1976-10-31 |
| SE431875B (sv) | 1984-03-05 |
| SU728719A3 (ru) | 1980-04-15 |
| BE841266A (fr) | 1976-10-29 |
| ZA762562B (en) | 1977-04-27 |
| AU1339076A (en) | 1977-11-03 |
| SE7604908L (sv) | 1976-10-31 |
| AU500439B2 (en) | 1979-05-24 |
| JPS51133262A (en) | 1976-11-18 |
| NL7604049A (nl) | 1976-11-02 |
| ATA302676A (de) | 1978-01-15 |
| ES447433A1 (es) | 1977-07-01 |
| CA1061335A (en) | 1979-08-28 |
| FR2309234B1 (de) | 1978-08-25 |
| NL179587B (nl) | 1986-05-01 |
| NL179587C (nl) | 1986-10-01 |
| DE2618822B2 (de) | 1982-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee | ||
| ELA | Expired due to lapse of time | ||
| ELI | Erroneous lapse | ||
| ELJ | Ceased due to non-payment of the annual fee |