AT344698B - Verfahren zur herstellung von neuen n4-substituierten 5-phenyl-1,3,4,5-tetrahydro-2h-1,4-benzodiazepin-2-on-derivaten - Google Patents

Verfahren zur herstellung von neuen n4-substituierten 5-phenyl-1,3,4,5-tetrahydro-2h-1,4-benzodiazepin-2-on-derivaten

Info

Publication number
AT344698B
AT344698B AT481975A AT481975A AT344698B AT 344698 B AT344698 B AT 344698B AT 481975 A AT481975 A AT 481975A AT 481975 A AT481975 A AT 481975A AT 344698 B AT344698 B AT 344698B
Authority
AT
Austria
Prior art keywords
benzodiazepine
tetrahydro
phenyl
derivatives
substituted
Prior art date
Application number
AT481975A
Other languages
German (de)
English (en)
Other versions
ATA481975A (de
Inventor
Lajos Chem Ing Dr Kisfaludy
Juliana Chem Ing Roehricht
Laszlo Chem Ing Ueroegdi
Szabolcs Dr Szeberenyi
Eva Dr Palosi
Laszlo Dr Szporny
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ATA481975A publication Critical patent/ATA481975A/de
Application granted granted Critical
Publication of AT344698B publication Critical patent/AT344698B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT481975A 1974-06-25 1975-06-24 Verfahren zur herstellung von neuen n4-substituierten 5-phenyl-1,3,4,5-tetrahydro-2h-1,4-benzodiazepin-2-on-derivaten AT344698B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HURI540A HU170623B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1974-06-25 1974-06-25

Publications (2)

Publication Number Publication Date
ATA481975A ATA481975A (de) 1977-12-15
AT344698B true AT344698B (de) 1978-08-10

Family

ID=11000952

Family Applications (1)

Application Number Title Priority Date Filing Date
AT481975A AT344698B (de) 1974-06-25 1975-06-24 Verfahren zur herstellung von neuen n4-substituierten 5-phenyl-1,3,4,5-tetrahydro-2h-1,4-benzodiazepin-2-on-derivaten

Country Status (21)

Country Link
US (1) US4021421A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (2) JPS541716B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT344698B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU499054B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BE (1) BE830582A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
BG (2) BG32570A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1047493A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (2) CH632254A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CS (1) CS195707B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD123887A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE2527901A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK284675A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2276054A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1509445A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU170623B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL47495A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7507556A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL101952B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE423711B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU1080744A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
YU (1) YU161075A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU187262B (en) * 1979-08-16 1985-12-28 Richter Gedeon Vegyeszet Process for preparing new tetrahydro-1,4-benzodiazepin-2-ones
WO2000073284A2 (en) 1999-05-26 2000-12-07 Du Pont Pharmaceuticals Company 1,4-benzodiazepin-2-ones useful as hiv reverse transcriptase inhibitors
CN105716725B (zh) * 2016-03-10 2019-02-12 中国科学院光电技术研究所 一种基于叠层扫描的相位差波前探测和图像复原方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236838A (en) * 1964-06-09 1966-02-22 Hoffmann La Roche Certain 1-substituted-benzodiazepin-2-one compounds

Also Published As

Publication number Publication date
CA1047493A (en) 1979-01-30
JPS5119783A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1976-02-17
JPS5377079A (en) 1978-07-08
ATA481975A (de) 1977-12-15
FR2276054B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-08-10
AU499054B2 (en) 1979-04-05
CS195707B2 (en) 1980-02-29
IL47495A0 (en) 1975-08-31
BG32569A3 (en) 1982-08-16
CH632254A5 (de) 1982-09-30
BE830582A (fr) 1975-10-16
IL47495A (en) 1979-03-12
GB1509445A (en) 1978-05-04
DK284675A (da) 1975-12-26
DE2527901A1 (de) 1976-01-15
US4021421A (en) 1977-05-03
JPS541716B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1979-01-27
BG32570A3 (en) 1982-08-16
FR2276054A1 (fr) 1976-01-23
SE7507039L (sv) 1975-12-29
HU170623B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-07-28
JPS6026113B2 (ja) 1985-06-21
DD123887A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1977-01-19
NL7507556A (nl) 1975-12-30
AU8223875A (en) 1976-12-23
PL101952B1 (pl) 1979-02-28
SE423711B (sv) 1982-05-24
CH634835A5 (de) 1983-02-28
YU161075A (en) 1983-01-21
SU1080744A3 (ru) 1984-03-15

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ELJ Ceased due to non-payment of the annual fee