FR2276054A1 - Nouveaux derives de la benzodiazepine et leur procede de preparation - Google Patents

Nouveaux derives de la benzodiazepine et leur procede de preparation

Info

Publication number
FR2276054A1
FR2276054A1 FR7519196A FR7519196A FR2276054A1 FR 2276054 A1 FR2276054 A1 FR 2276054A1 FR 7519196 A FR7519196 A FR 7519196A FR 7519196 A FR7519196 A FR 7519196A FR 2276054 A1 FR2276054 A1 FR 2276054A1
Authority
FR
France
Prior art keywords
benzodiazepine
preparation process
new derivatives
derivatives
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7519196A
Other languages
English (en)
Other versions
FR2276054B1 (fr
Inventor
Lajos Kisfaludy
Julianna Rohricht
Laszlo Urogdi
Szabolcs Szeberenyi
Eva Palosi
Laszlo Szporny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of FR2276054A1 publication Critical patent/FR2276054A1/fr
Application granted granted Critical
Publication of FR2276054B1 publication Critical patent/FR2276054B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
FR7519196A 1974-06-25 1975-06-19 Nouveaux derives de la benzodiazepine et leur procede de preparation Granted FR2276054A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HURI540A HU170623B (fr) 1974-06-25 1974-06-25

Publications (2)

Publication Number Publication Date
FR2276054A1 true FR2276054A1 (fr) 1976-01-23
FR2276054B1 FR2276054B1 (fr) 1979-08-10

Family

ID=11000952

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7519196A Granted FR2276054A1 (fr) 1974-06-25 1975-06-19 Nouveaux derives de la benzodiazepine et leur procede de preparation

Country Status (21)

Country Link
US (1) US4021421A (fr)
JP (2) JPS541716B2 (fr)
AT (1) AT344698B (fr)
AU (1) AU499054B2 (fr)
BE (1) BE830582A (fr)
BG (2) BG32570A3 (fr)
CA (1) CA1047493A (fr)
CH (2) CH632254A5 (fr)
CS (1) CS195707B2 (fr)
DD (1) DD123887A5 (fr)
DE (1) DE2527901A1 (fr)
DK (1) DK284675A (fr)
FR (1) FR2276054A1 (fr)
GB (1) GB1509445A (fr)
HU (1) HU170623B (fr)
IL (1) IL47495A (fr)
NL (1) NL7507556A (fr)
PL (1) PL101952B1 (fr)
SE (1) SE423711B (fr)
SU (1) SU1080744A3 (fr)
YU (1) YU161075A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463131A1 (fr) * 1979-08-16 1981-02-20 Richter Gedeon Vegyeszet Nouvelles 5-phenyl-1,3,4,5-tetrahydro-2h-1,4-benzodiazepin-2-ones contenant dans les positions 3 et 5 des centres d'asymetrie a configuration absolue semblable, procede pour leur preparation et leur application en therapeutique

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1183242A2 (fr) 1999-05-26 2002-03-06 Du Pont Pharmaceuticals Company Inhibiteurs de transcriptase inverse du vih a base de 1,4-benzodiazepin-2-ones
CN105716725B (zh) * 2016-03-10 2019-02-12 中国科学院光电技术研究所 一种基于叠层扫描的相位差波前探测和图像复原方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236838A (en) * 1964-06-09 1966-02-22 Hoffmann La Roche Certain 1-substituted-benzodiazepin-2-one compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463131A1 (fr) * 1979-08-16 1981-02-20 Richter Gedeon Vegyeszet Nouvelles 5-phenyl-1,3,4,5-tetrahydro-2h-1,4-benzodiazepin-2-ones contenant dans les positions 3 et 5 des centres d'asymetrie a configuration absolue semblable, procede pour leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
JPS5119783A (fr) 1976-02-17
HU170623B (fr) 1977-07-28
US4021421A (en) 1977-05-03
AU8223875A (en) 1976-12-23
BG32569A3 (en) 1982-08-16
SE7507039L (sv) 1975-12-26
YU161075A (en) 1983-01-21
SE423711B (sv) 1982-05-24
NL7507556A (nl) 1975-12-30
JPS6026113B2 (ja) 1985-06-21
IL47495A (en) 1979-03-12
SU1080744A3 (ru) 1984-03-15
BG32570A3 (en) 1982-08-16
AT344698B (de) 1978-08-10
JPS541716B2 (fr) 1979-01-27
GB1509445A (en) 1978-05-04
CS195707B2 (en) 1980-02-29
DD123887A5 (fr) 1977-01-19
AU499054B2 (en) 1979-04-05
JPS5377079A (en) 1978-07-08
CA1047493A (fr) 1979-01-30
DE2527901A1 (de) 1976-01-15
DK284675A (da) 1975-12-26
BE830582A (fr) 1975-10-16
PL101952B1 (pl) 1979-02-28
ATA481975A (de) 1977-12-15
FR2276054B1 (fr) 1979-08-10
CH632254A5 (de) 1982-09-30
CH634835A5 (de) 1983-02-28
IL47495A0 (en) 1975-08-31

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Legal Events

Date Code Title Description
ST Notification of lapse