AT343659B - METHOD FOR PRODUCING NEW BENZIMIDAZOLE DERIVATIVES AND THEIR ACID ADDITION SALTS - Google Patents

METHOD FOR PRODUCING NEW BENZIMIDAZOLE DERIVATIVES AND THEIR ACID ADDITION SALTS

Info

Publication number
AT343659B
AT343659B AT113775A AT113775A AT343659B AT 343659 B AT343659 B AT 343659B AT 113775 A AT113775 A AT 113775A AT 113775 A AT113775 A AT 113775A AT 343659 B AT343659 B AT 343659B
Authority
AT
Austria
Prior art keywords
acid addition
addition salts
benzimidazole derivatives
producing new
new benzimidazole
Prior art date
Application number
AT113775A
Other languages
German (de)
Other versions
ATA113775A (en
Inventor
Peder Bernhard Berntsson
Stig Ake Ingemar Carlsson
Lars Erik Garberg
Ulf Krister Junggren
Sven Erik Sjostrand
Sundell Gunhild Wika V Wittken
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of ATA113775A publication Critical patent/ATA113775A/en
Application granted granted Critical
Publication of AT343659B publication Critical patent/AT343659B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
AT113775A 1974-02-18 1975-02-17 METHOD FOR PRODUCING NEW BENZIMIDAZOLE DERIVATIVES AND THEIR ACID ADDITION SALTS AT343659B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7402101A SE418966B (en) 1974-02-18 1974-02-18 ANALOGY PROCEDURE FOR THE PREPARATION OF COMPOUNDS WITH Gastric Acid Secretion Inhibitory Effects

Publications (2)

Publication Number Publication Date
ATA113775A ATA113775A (en) 1977-10-15
AT343659B true AT343659B (en) 1978-06-12

Family

ID=20320233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT113775A AT343659B (en) 1974-02-18 1975-02-17 METHOD FOR PRODUCING NEW BENZIMIDAZOLE DERIVATIVES AND THEIR ACID ADDITION SALTS

Country Status (23)

Country Link
JP (1) JPS5924157B2 (en)
AT (1) AT343659B (en)
AU (1) AU499639B2 (en)
BE (1) BE825655A (en)
CA (1) CA1060448A (en)
CH (1) CH616160A5 (en)
CS (1) CS194715B2 (en)
DD (1) DD119422A5 (en)
DE (1) DE2504252A1 (en)
DK (1) DK141122B (en)
FI (1) FI59590C (en)
FR (1) FR2261007B1 (en)
GB (1) GB1500043A (en)
HK (1) HK67080A (en)
HU (1) HU172141B (en)
IE (1) IE40858B1 (en)
LU (1) LU71872A1 (en)
MY (1) MY8100208A (en)
NL (1) NL7501917A (en)
NO (1) NO142401C (en)
SE (1) SE418966B (en)
SU (1) SU795476A3 (en)
ZA (1) ZA75558B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT374471B (en) * 1978-04-14 1984-04-25 Haessle Ab METHOD FOR PRODUCING NEW 2PYRIDYLALKYL-SULFINYL-BENZIMIDAZOLES AND THEIR HYDRATES, STEREOISOMERS AND SALTS

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE416649B (en) * 1974-05-16 1981-01-26 Haessle Ab PROCEDURE FOR THE PREPARATION OF SUBSTANCES WHICH PREVENT Gastric acid secretion
JPS5364103A (en) * 1976-09-24 1978-06-08 Hitachi Ltd Waste heat recovery boiler
IN148930B (en) 1977-09-19 1981-07-25 Hoffmann La Roche
US4343805A (en) * 1978-12-16 1982-08-10 John Wyeth & Brother Limited Heterocyclic compounds
CH644116A5 (en) * 1980-08-21 1984-07-13 Hoffmann La Roche IMIDAZOLE DERIVATIVES.
DE3047388A1 (en) * 1980-12-16 1982-07-15 Basf Ag, 6700 Ludwigshafen ISATOGEN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS FUNGICIDES
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
DE3216843C2 (en) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridine derivatives, processes for their preparation and pharmaceuticals containing these compounds
US4552886A (en) * 1982-06-07 1985-11-12 Eli Lilly And Company Fungicidal pyridylmethyl-amines
SE8300736D0 (en) * 1983-02-11 1983-02-11 Haessle Ab NOVEL PHARMACOLOGICALLY ACTIVE COMPOUNDS
GB8307865D0 (en) * 1983-03-22 1983-04-27 Fujisawa Pharmaceutical Co Benzimidazole derivatives
US4503139A (en) * 1983-05-09 1985-03-05 Polaroid Corporation Photographic products and processes and novel compounds
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
US4767770A (en) * 1984-06-18 1988-08-30 Eli Lilly And Company Method of inhibiting aromatase
SE8505112D0 (en) * 1985-10-29 1985-10-29 Haessle Ab NOVEL PHARMACOLOGICAL COMPOUNDS
FR2593178B1 (en) * 1986-01-20 1988-04-29 Esteve Labor Dr 2-BENZIMIDAZOLYLALKYLTHIO (OR SULFINYL OR SULFONYL) DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS.
SE8600658D0 (en) * 1986-02-14 1986-02-14 Haessle Ab NOVEL COMPOSITION OF MATTER
SE8604566D0 (en) * 1986-10-27 1986-10-27 Haessle Ab NOVEL COMPUNDS
SE8604998D0 (en) 1986-11-21 1986-11-21 Haessle Ab NOVEL PHARMACOLOGICAL COMPOUNDS
NZ234564A (en) 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
WO1989005643A1 (en) * 1987-12-18 1989-06-29 Pfizer Inc. Heterocyclic-substituted quinoline-carboxylic acids
JPH021280U (en) * 1988-06-14 1990-01-08
KR920003928B1 (en) * 1988-09-20 1992-05-18 히사미쯔세이야꾸 가부시기가이샤 NOVEL DIBENZ |b,e¨ OXEPIN DERIVATIVES
SE8804629D0 (en) 1988-12-22 1988-12-22 Ab Haessle NEW THERAPEUTICALLY ACTIVE COMPOUNDS
IE64199B1 (en) * 1988-12-22 1995-07-12 Haessle Ab Compound with gastric acid inhibitory effect and process for its preparation
SE8804628D0 (en) 1988-12-22 1988-12-22 Ab Haessle NEW COMPOUNDS
JP2679745B2 (en) * 1989-06-29 1997-11-19 明治製菓株式会社 Azole derivatives and antiulcer agents containing them as active ingredients
JPH0347053U (en) * 1989-09-16 1991-04-30
US5049674A (en) 1989-12-20 1991-09-17 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US5274099A (en) * 1989-12-20 1993-12-28 Aktiebolaget Hassle Therapeutically active fluoro substituted benzimidazoles
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
SE9002206D0 (en) 1990-06-20 1990-06-20 Haessle Ab NEW COMPOUNDS
PL372409A1 (en) 2002-03-27 2005-07-25 Altana Pharma Ag Novel alkoxypyridine-derivatives
CN1751043A (en) 2003-02-25 2006-03-22 奥坦纳医药公司 Imidazo[4,5-b]quinoline-derivatives and their use as no-synthase inhibitors
ATE399168T1 (en) 2003-10-01 2008-07-15 Nycomed Gmbh IMIDAZOPYRIDINE DERIVATIVES AND THEIR USE AS INDUCIBLE NO-SYNTHASE INHIBITORS
KR20060092221A (en) 2003-10-01 2006-08-22 알타나 파마 아게 - 45- imidazo[45-b]pyridine-derivatives as inducible no-synthase inhibitors
EA010261B1 (en) * 2003-10-01 2008-06-30 Алтана Фарма Аг Imidazoryridine-derivatives as inductible no-synthase inhibitors
US20080125460A1 (en) * 2003-10-01 2008-05-29 Altana Pharma Ag Imidazopyridine-Derivatives As Inducible No-Synthase Inhibitors
NZ546394A (en) * 2003-10-01 2009-08-28 Altana Pharma Ag Aminopyridine derivatives as inductible NO-synthase inhibitors
EP2070923A1 (en) 2007-12-11 2009-06-17 Bayer CropScience AG Insecticide iminoheterocycles
JP5911476B2 (en) * 2010-05-26 2016-04-27 スノビオン プハルマセウトイカルス インコーポレイテッド Heteroaryl compounds and methods of use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1234058A (en) * 1968-10-21 1971-06-03

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT374471B (en) * 1978-04-14 1984-04-25 Haessle Ab METHOD FOR PRODUCING NEW 2PYRIDYLALKYL-SULFINYL-BENZIMIDAZOLES AND THEIR HYDRATES, STEREOISOMERS AND SALTS

Also Published As

Publication number Publication date
DE2504252C2 (en) 1989-02-02
DK141122C (en) 1980-07-07
FI750421A (en) 1975-08-19
JPS5924157B2 (en) 1984-06-07
FI59590B (en) 1981-05-29
DD119422A5 (en) 1976-04-20
DK141122B (en) 1980-01-21
DK54075A (en) 1975-10-20
HK67080A (en) 1980-12-05
ZA75558B (en) 1976-01-28
AU499639B2 (en) 1979-04-26
SE418966B (en) 1981-07-06
NO142401C (en) 1980-08-13
NO142401B (en) 1980-05-05
CA1060448A (en) 1979-08-14
ATA113775A (en) 1977-10-15
LU71872A1 (en) 1975-12-09
CS194715B2 (en) 1979-12-31
SU795476A3 (en) 1981-01-07
IE40858B1 (en) 1979-08-29
GB1500043A (en) 1978-02-08
IE40858L (en) 1975-08-18
AU7820675A (en) 1976-08-19
FR2261007A1 (en) 1975-09-12
SE7402101L (en) 1975-08-19
FR2261007B1 (en) 1978-11-24
BE825655A (en) 1975-08-18
DE2504252A1 (en) 1975-08-21
HU172141B (en) 1978-06-28
FI59590C (en) 1981-09-10
NO750541L (en) 1975-08-19
JPS50116474A (en) 1975-09-11
MY8100208A (en) 1981-12-31
CH616160A5 (en) 1980-03-14
NL7501917A (en) 1975-08-20

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee