AT316552B - Verfahren zur Herstellung von neuen unsymmetrischen 1,4-Dihydropyridinen - Google Patents
Verfahren zur Herstellung von neuen unsymmetrischen 1,4-DihydropyridinenInfo
- Publication number
- AT316552B AT316552B AT301772A AT301772A AT316552B AT 316552 B AT316552 B AT 316552B AT 301772 A AT301772 A AT 301772A AT 301772 A AT301772 A AT 301772A AT 316552 B AT316552 B AT 316552B
- Authority
- AT
- Austria
- Prior art keywords
- dihydropyridines
- preparation
- new asymmetrical
- asymmetrical
- new
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2117572A DE2117572C3 (de) | 1971-04-10 | 1971-04-10 | Unsymmetrische 1,4-Dihydropyridin ^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
AT316552B true AT316552B (de) | 1974-07-25 |
Family
ID=5804434
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT301772A AT316552B (de) | 1971-04-10 | 1972-04-07 | Verfahren zur Herstellung von neuen unsymmetrischen 1,4-Dihydropyridinen |
Country Status (27)
Country | Link |
---|---|
US (1) | US3799936A (de) |
JP (1) | JPS5527054B1 (de) |
AT (1) | AT316552B (de) |
AU (1) | AU459338B2 (de) |
BE (1) | BE781879A (de) |
BG (4) | BG20106A3 (de) |
CA (1) | CA925513A (de) |
CH (2) | CH571493A5 (de) |
CS (2) | CS177821B2 (de) |
DD (1) | DD104519A5 (de) |
DE (1) | DE2117572C3 (de) |
DK (1) | DK132321C (de) |
ES (1) | ES401615A1 (de) |
FI (1) | FI55187C (de) |
FR (1) | FR2132831B1 (de) |
GB (1) | GB1331405A (de) |
HU (1) | HU165875B (de) |
IE (1) | IE36947B1 (de) |
IL (1) | IL39170A (de) |
LU (1) | LU65129A1 (de) |
NL (1) | NL170140C (de) |
NO (1) | NO133711C (de) |
PL (2) | PL84571B1 (de) |
RO (2) | RO59959A (de) |
SE (1) | SE371824B (de) |
SU (2) | SU431671A3 (de) |
ZA (1) | ZA722355B (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2210672C3 (de) * | 1972-03-06 | 1980-03-20 | Bayer Ag, 5090 Leverkusen | N-substituierte unsymmetrische 1 ^-Dihydropyridin-S^-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
US3917619A (en) * | 1972-03-06 | 1975-11-04 | Bayer Ag | 2-Amino-4,5-dihydropyridine derivatives |
US3920823A (en) * | 1972-03-06 | 1975-11-18 | Bayer Ag | Use of unsymmetrical esters of n-substituted 1,4-dihydropyridine 3,5-dicarboxylic acid as cardio-vascular agents |
US3857849A (en) * | 1973-02-28 | 1974-12-31 | Bayer Ag | 2-amino-1,4-dihydropyridine derivatives |
US3860601A (en) * | 1972-03-06 | 1975-01-14 | Horst Meyer | 2,6-diamino-1,4-dihydropyridine derivatives |
US3917620A (en) * | 1972-03-06 | 1975-11-04 | Bayer Ag | 2-Amino-4,5-dihydropyridine derivatives |
US4001258A (en) * | 1972-03-06 | 1977-01-04 | Bayer Aktiengesellschaft | 2-amino-1,4-dihydropyridine derivatives |
US3988458A (en) * | 1972-03-06 | 1976-10-26 | Bayer Aktiengesellschaft | Bicyclic derivatives of 1,4-dihydropyridine 3,5-carboxylic acid esters |
DE2210674C3 (de) * | 1972-03-06 | 1981-09-24 | Bayer Ag, 5090 Leverkusen | 2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel |
US3917622A (en) * | 1972-03-06 | 1975-11-04 | Bayer Ag | 2-Amino-1,4-dihydropyridine derivatives |
US3935223A (en) * | 1972-03-06 | 1976-01-27 | Bayer Aktiengesellschaft | 2-Amino-1,4-dihydropyridine derivatives |
US3939171A (en) * | 1972-03-06 | 1976-02-17 | Bayer Aktiengesellschaft | 2-Amino-1,4-dihydropyridine derivatives |
DD106832A5 (de) * | 1972-03-06 | 1974-07-05 | ||
US3989708A (en) * | 1972-08-31 | 1976-11-02 | Bayer Aktiengesellschaft | 2-Amino-1,4-dihydropyridine derivatives |
DE2242786A1 (de) * | 1972-08-31 | 1974-03-14 | Bayer Ag | Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel |
DE2248150A1 (de) * | 1972-09-30 | 1974-04-04 | Bayer Ag | Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
GB1409865A (en) * | 1973-02-13 | 1975-10-15 | Science Union & Cie | Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them |
DK152285C (da) * | 1975-07-02 | 1988-10-10 | Fujisawa Pharmaceutical Co | Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater |
FR2405937A1 (fr) * | 1977-10-14 | 1979-05-11 | Labaz | Nouveaux derives de dihydropyridine, leur procede de preparation et leur application |
SE429652B (sv) * | 1978-06-30 | 1983-09-19 | Haessle Ab | 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester |
SE7910521L (sv) * | 1979-12-20 | 1981-06-21 | Haessle Ab | Nya 2-metyl-6-substituerade-4-(2,3-disubstituerad fenyl)-1,4-dihydropyridin-3,5-diestrar med hypotesiva egenskaper, samt forfarande for deras framstellning, och farmaceutiska beredningar innehallande desamma |
JPS60120861A (ja) * | 1983-12-02 | 1985-06-28 | Otsuka Pharmaceut Co Ltd | ジヒドロピリジン誘導体 |
IE57810B1 (en) * | 1984-03-27 | 1993-04-21 | Delagrange Lab | 1,4-dihydropyridine derivatives,their preparation and their use |
JPS6143165A (ja) * | 1984-08-07 | 1986-03-01 | Otsuka Pharmaceut Co Ltd | ジヒドロピリジン誘導体の製造法 |
US5571827A (en) * | 1990-03-13 | 1996-11-05 | Sepracor Inc. | Methods and compositions for treating hypertension, angina and other disorders using optically pure s(-) nitrendipine |
AU3128693A (en) * | 1991-11-18 | 1993-06-15 | G.D. Searle & Co. | 2-(4-substituted)phenylmethylene derivatives and methods of use |
PT657432E (pt) * | 1993-12-10 | 2003-07-31 | Bayer Ag | 1,4-di-hidropiridinas fenil-substituidas com actividade cerebral |
EE03192B1 (et) * | 1993-12-10 | 1999-06-15 | Bayer Aktiengesellschaft | Isopropüül-(2-metoksüetüül)-4-(2-kloro-3-tsüanofenüül)-1,4-dihüdro-2,6-dimetüülpüri diin-3,5-dikarboksülaat, selle enantiomeerid ja vaheühend, meetodid nimetatud ühendite valmistamiseks ja kasutamine |
DE19727350C1 (de) * | 1997-06-27 | 1999-01-21 | Bayer Ag | Verfahren zur Herstellung von Nifedipin |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1923990C3 (de) * | 1969-05-10 | 1978-11-23 | Bayer Ag | Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern |
-
1971
- 1971-04-10 DE DE2117572A patent/DE2117572C3/de not_active Expired
-
1972
- 1972-03-09 CH CH1159775A patent/CH571493A5/xx not_active IP Right Cessation
- 1972-03-09 CH CH345972A patent/CH571491A5/xx not_active IP Right Cessation
- 1972-03-27 AU AU40454/72A patent/AU459338B2/en not_active Expired
- 1972-04-05 SU SU1768162A patent/SU431671A3/ru active
- 1972-04-05 SU SU1932086A patent/SU475771A3/ru active
- 1972-04-06 BG BG23739A patent/BG20106A3/xx unknown
- 1972-04-06 FI FI947/72A patent/FI55187C/fi active
- 1972-04-06 BG BG23740A patent/BG19374A3/xx unknown
- 1972-04-06 BG BG23738A patent/BG19595A3/xx unknown
- 1972-04-06 BG BG20165A patent/BG20353A3/xx unknown
- 1972-04-07 NL NLAANVRAGE7204694,A patent/NL170140C/xx not_active IP Right Cessation
- 1972-04-07 AT AT301772A patent/AT316552B/de not_active IP Right Cessation
- 1972-04-07 DD DD162141A patent/DD104519A5/xx unknown
- 1972-04-07 NO NO1191/72A patent/NO133711C/no unknown
- 1972-04-07 DK DK172272A patent/DK132321C/da not_active IP Right Cessation
- 1972-04-07 ZA ZA722355A patent/ZA722355B/xx unknown
- 1972-04-07 US US00242238A patent/US3799936A/en not_active Expired - Lifetime
- 1972-04-07 JP JP3450672A patent/JPS5527054B1/ja active Pending
- 1972-04-07 IE IE455/72A patent/IE36947B1/xx unknown
- 1972-04-07 LU LU65129D patent/LU65129A1/xx unknown
- 1972-04-08 PL PL1972154621A patent/PL84571B1/pl unknown
- 1972-04-08 PL PL1972175387A patent/PL92407B1/pl unknown
- 1972-04-08 ES ES401615A patent/ES401615A1/es not_active Expired
- 1972-04-10 RO RO197270489A patent/RO59959A/ro unknown
- 1972-04-10 CA CA139294A patent/CA925513A/en not_active Expired
- 1972-04-10 BE BE781879A patent/BE781879A/xx not_active IP Right Cessation
- 1972-04-10 HU HUBA2728A patent/HU165875B/hu unknown
- 1972-04-10 SE SE7204607A patent/SE371824B/xx unknown
- 1972-04-10 GB GB1646372A patent/GB1331405A/en not_active Expired
- 1972-04-10 RO RO197279438A patent/RO63113A/ro unknown
- 1972-04-10 IL IL7239170A patent/IL39170A/xx unknown
- 1972-04-10 CS CS2378A patent/CS177821B2/cs unknown
- 1972-04-10 CS CS3558A patent/CS177846B2/cs unknown
- 1972-04-10 FR FR7212513A patent/FR2132831B1/fr not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ELA | Expired due to lapse of time |