AR245953A1 - Sistema de perhidrolisis de enzimatico para generacion in situ de peracido y procedimiento para blanquear materiales con el mismo. - Google Patents

Sistema de perhidrolisis de enzimatico para generacion in situ de peracido y procedimiento para blanquear materiales con el mismo.

Info

Publication number
AR245953A1
AR245953A1 AR87309308A AR30930887A AR245953A1 AR 245953 A1 AR245953 A1 AR 245953A1 AR 87309308 A AR87309308 A AR 87309308A AR 30930887 A AR30930887 A AR 30930887A AR 245953 A1 AR245953 A1 AR 245953A1
Authority
AR
Argentina
Prior art keywords
substrate
bleaching system
peroxygen
reacts
enzyme
Prior art date
Application number
AR87309308A
Other languages
English (en)
Original Assignee
Clorox Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clorox Co filed Critical Clorox Co
Application granted granted Critical
Publication of AR245953A1 publication Critical patent/AR245953A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/39—Organic or inorganic per-compounds
    • C11D3/3945—Organic per-compounds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/2093—Esters; Carbonates
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/39—Organic or inorganic per-compounds
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/39—Organic or inorganic per-compounds
    • C11D3/3902—Organic or inorganic per-compounds combined with specific additives
    • C11D3/3905—Bleach activators or bleach catalysts
    • C11D3/3907—Organic compounds
    • C11D3/391—Oxygen-containing compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • D—TEXTILES; PAPER
    • D06—TREATMENT OF TEXTILES OR THE LIKE; LAUNDERING; FLEXIBLE MATERIALS NOT OTHERWISE PROVIDED FOR
    • D06L—DRY-CLEANING, WASHING OR BLEACHING FIBRES, FILAMENTS, THREADS, YARNS, FABRICS, FEATHERS OR MADE-UP FIBROUS GOODS; BLEACHING LEATHER OR FURS
    • D06L4/00—Bleaching fibres, filaments, threads, yarns, fabrics, feathers or made-up fibrous goods; Bleaching leather or furs
    • D06L4/40—Bleaching fibres, filaments, threads, yarns, fabrics, feathers or made-up fibrous goods; Bleaching leather or furs using enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Textile Engineering (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

UN SISTEMA DE PERHIDROLISIS ENZIMATICA PARA GENERACION IN SITU DE PERACIDO, QUE COMPRENDE: (A) UNA ENZIMA DE QUE TIENE ACTIVIDAD DE HIDROLASA Y ES AISLABLE DE PSEUDOMONAS PUTIDA ATCC 53552 O SUSMUTANTES Y VARIANTES; (B) UN SUBSTRATO HIDROLIZABLE PARA LA ENZIMA (A); Y (C) UNA FUENTE DE PEROXIGENO QUE REACCIONA CON (A), TENIENDO DICHO SUBSTRATO LA ESTRUCTURA (I), EN DONDE R ES UN SUBSTITUYENTE QUE INCLUYE UN ATOMO DE CARBONO Y X ES UNA PORCION FUNCIONAL O UN GRUPO HIDROCARBURO; Y (D) UNA FUENTE DE PEROXIGENO QUE REACCIONA CON (A) Y (B) PARA PRODUCIR PERACIDO EN PRESENCIA DE UNA SOLUCION ACUOSA DE SUSPENSION DEL SUBSTRATO.
AR87309308A 1986-11-19 1987-11-16 Sistema de perhidrolisis de enzimatico para generacion in situ de peracido y procedimiento para blanquear materiales con el mismo. AR245953A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/932,717 US5030240A (en) 1986-06-09 1986-11-19 Enzymatic peracid bleaching system

Publications (1)

Publication Number Publication Date
AR245953A1 true AR245953A1 (es) 1994-03-30

Family

ID=25462790

Family Applications (1)

Application Number Title Priority Date Filing Date
AR87309308A AR245953A1 (es) 1986-11-19 1987-11-16 Sistema de perhidrolisis de enzimatico para generacion in situ de peracido y procedimiento para blanquear materiales con el mismo.

Country Status (11)

Country Link
US (1) US5030240A (es)
EP (1) EP0268456B1 (es)
JP (1) JP3077700B2 (es)
AR (1) AR245953A1 (es)
AT (1) ATE71653T1 (es)
AU (1) AU599436B2 (es)
DE (1) DE3776089D1 (es)
ES (1) ES2030075T3 (es)
GR (1) GR3004391T3 (es)
MX (1) MX166926B (es)
TR (1) TR23330A (es)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352594A (en) * 1984-05-29 1994-10-04 Genecor, Inc. Selection and method of making enzymes for perhydrolysis system and for altering substrate specificity, specific activity and catalytic efficiency
US5278066A (en) * 1985-08-09 1994-01-11 Gist-Brocades Nv Molecular cloning and expression of gene encoding lipolytic enzyme
AU603101B2 (en) * 1986-06-09 1990-11-08 Clorox Company, The Enzymatic perhydrolysis system and method of use for bleaching
US5364554A (en) * 1986-06-09 1994-11-15 The Clorox Company Proteolytic perhydrolysis system and method of use for bleaching
US5296161A (en) * 1986-06-09 1994-03-22 The Clorox Company Enzymatic perhydrolysis system and method of use for bleaching
US5108457A (en) * 1986-11-19 1992-04-28 The Clorox Company Enzymatic peracid bleaching system with modified enzyme
US5830735A (en) * 1987-03-06 1998-11-03 Gist-Brocades Nv Method for producing lipolytic enzymes using transformed Pseudomonas
US5512203A (en) * 1987-05-29 1996-04-30 Genencor International, Inc. Cutinase cleaning compositions
US5240851A (en) * 1988-02-22 1993-08-31 Fina Research, S.A. Lipase-producing Pseudomonas aeruginosa strain
EP0334462B2 (en) † 1988-03-25 2002-04-24 Genencor International, Inc. Molecular cloning and expression of genes encoding lipolytic enzymes
US5292448A (en) * 1988-05-10 1994-03-08 Lever Brothers Company, Division Of Conopco, Inc. Enzymatic detergent composition
DK352988D0 (da) * 1988-06-27 1988-06-27 Novo Industri As Enzymatisk blegende detergent baseret paa in situ dannelse af peroxysyrer og anvendelse af et saadant detergent
US5223169A (en) * 1989-05-15 1993-06-29 The Clorox Company Hydrolase surfactant systems and their use in laundering
EP0399681B1 (en) * 1989-05-15 2000-01-19 The Clorox Company Method of laundering fabrics
US5541092A (en) * 1989-09-12 1996-07-30 Novo Nordisk A/S Process for preparing peroxycarboxylic acids using lipase in a non-aqueous medium
EP0476915B1 (en) 1990-09-14 1997-05-14 The Clorox Company Lipase-surface complex and methods of formation and use
US5308765A (en) * 1991-05-15 1994-05-03 Mitsubishi Rayon Co., Ltd. Esterase genes, esterase, recombinant plasmids and transformants containing the recombinant plasmid and methods of producing optically acitve carboxylic acids and their enantiomeric esters using said transformants
US5431843A (en) * 1991-09-04 1995-07-11 The Clorox Company Cleaning through perhydrolysis conducted in dense fluid medium
US5338474A (en) * 1992-02-25 1994-08-16 Lever Brothers Company, Division Of Conopco, Inc. System for releasing bleach from a bleach precursor in the wash using an enzyme activator
US5429950A (en) * 1992-03-30 1995-07-04 Genencor International, Inc. Heterologous gene expression in bacillus subtilis: fusion approach
DK154292D0 (da) * 1992-12-23 1992-12-23 Novo Nordisk As Nyt enzym
EP0736597A1 (en) * 1995-04-03 1996-10-09 The Procter & Gamble Company Soaker compositions
EP0756001A1 (en) * 1995-07-24 1997-01-29 The Procter & Gamble Company Detergent compositions comprising specific amylase and a specific surfactant system
DE19930960A1 (de) * 1999-07-05 2001-01-18 Bayer Ag Verfahren zur Oxidation von organischen Verbindungen
US7226771B2 (en) 2002-04-19 2007-06-05 Diversa Corporation Phospholipases, nucleic acids encoding them and methods for making and using them
US7943360B2 (en) 2002-04-19 2011-05-17 Verenium Corporation Phospholipases, nucleic acids encoding them and methods for making and using them
DK2853593T3 (en) 2003-03-07 2018-01-08 Dsm Ip Assets Bv Hydrolases, nucleic acids encoding them, and processes for their preparation and use
US7754460B2 (en) 2003-12-03 2010-07-13 Danisco Us Inc. Enzyme for the production of long chain peracid
CN103333870A (zh) * 2003-12-03 2013-10-02 丹尼斯科美国公司 过水解酶
US8476052B2 (en) * 2003-12-03 2013-07-02 Danisco Us Inc. Enzyme for the production of long chain peracid
CN103173282A (zh) * 2004-06-16 2013-06-26 帝斯曼知识产权资产管理有限公司 对叶绿素进行酶促脱色的组合物和方法
US20080070291A1 (en) 2004-06-16 2008-03-20 David Lam Compositions and Methods for Enzymatic Decolorization of Chlorophyll
WO2006031699A2 (en) 2004-09-10 2006-03-23 Diversa Corporation Compositions and methods for making and modifying oils
WO2006096834A2 (en) * 2005-03-08 2006-09-14 Diversa Corporation Hydrolases, nucleic acids encoding them and methods for improving paper strength
US20070082832A1 (en) * 2005-10-06 2007-04-12 Dicosimo Robert Enzymatic production of peracids from carboxylic acid ester substrates using non-heme haloperoxidases
WO2007067473A2 (en) * 2005-12-06 2007-06-14 Genencor International, Inc. Perhydrolase epitopes
CN102016050A (zh) * 2005-12-09 2011-04-13 金克克国际有限公司 用于去污的酰基转移酶
CA2643265C (en) * 2006-03-02 2014-07-29 Genencor Division Danisco Us, Inc. Surface active bleach and dynamic ph
MX2009003034A (es) 2006-09-21 2009-11-18 Verenium Corp Fosfolipasas, acidos nucleicos que las codifican, y metodos de hacerlas y usarlas.
WO2008140988A1 (en) * 2007-05-10 2008-11-20 Danisco Us Inc., Genencor Division Stable enzymatic peracid generating systems
ES2735230T3 (es) * 2008-10-03 2019-12-17 Du Pont Estabilización de perhidrolasas con excipientes
US8877254B2 (en) 2010-12-29 2014-11-04 Ecolab Usa Inc. In situ generation of peroxycarboxylic acids at alkaline pH, and methods of use thereof
WO2012090125A2 (en) 2010-12-29 2012-07-05 Ecolab Usa Inc. Sugar ester peracid on-site generator and formulator
PL2687094T3 (pl) 2010-12-29 2018-09-28 Ecolab Usa Inc. Wytwarzanie kwasów peroksykarboksylowych w zasadowym pH i ich zastosowanie jako czynniki wybielające tekstylia i czynniki przeciwmikrobiologiczne
AU2012244292B2 (en) 2011-11-04 2015-03-05 Bissell Inc. Enzyme cleaning composition and method of use
US9321664B2 (en) 2011-12-20 2016-04-26 Ecolab Usa Inc. Stable percarboxylic acid compositions and uses thereof
CN104254496B (zh) 2012-03-30 2016-10-26 艺康美国股份有限公司 过乙酸/过氧化氢和过氧化物还原剂用于处理钻井液、压裂液、回流水和排放水的用途
US20130284637A1 (en) 2012-04-30 2013-10-31 Danisco Us Inc. Unit-dose format perhydrolase systems
US20140308162A1 (en) 2013-04-15 2014-10-16 Ecolab Usa Inc. Peroxycarboxylic acid based sanitizing rinse additives for use in ware washing
US9994799B2 (en) 2012-09-13 2018-06-12 Ecolab Usa Inc. Hard surface cleaning compositions comprising phosphinosuccinic acid adducts and methods of use
US9752105B2 (en) 2012-09-13 2017-09-05 Ecolab Usa Inc. Two step method of cleaning, sanitizing, and rinsing a surface
US8871699B2 (en) 2012-09-13 2014-10-28 Ecolab Usa Inc. Detergent composition comprising phosphinosuccinic acid adducts and methods of use
US20140256811A1 (en) 2013-03-05 2014-09-11 Ecolab Usa Inc. Efficient stabilizer in controlling self accelerated decomposition temperature of peroxycarboxylic acid compositions with mineral acids
US8822719B1 (en) 2013-03-05 2014-09-02 Ecolab Usa Inc. Peroxycarboxylic acid compositions suitable for inline optical or conductivity monitoring
US10165774B2 (en) 2013-03-05 2019-01-01 Ecolab Usa Inc. Defoamer useful in a peracid composition with anionic surfactants
WO2015164677A1 (en) 2014-04-23 2015-10-29 Gregory Van Buskirk Cleaning formulations for chemically sensitive individuals: compositions and methods
WO2016100700A1 (en) 2014-12-18 2016-06-23 Ecolab Usa Inc. Methods for forming peroxyformic acid and uses thereof
US11040902B2 (en) 2014-12-18 2021-06-22 Ecolab Usa Inc. Use of percarboxylic acids for scale prevention in treatment systems
US9518013B2 (en) 2014-12-18 2016-12-13 Ecolab Usa Inc. Generation of peroxyformic acid through polyhydric alcohol formate
AU2016206650A1 (en) 2015-01-14 2017-08-10 Gregory Van Buskirk Improved fabric treatment method for stain release
FI3307427T3 (fi) 2015-06-09 2023-11-09 Danisco Us Inc Osmoottiset puhkeavat kapselit
WO2016201040A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc. Water-triggered enzyme suspension
WO2016201069A1 (en) 2015-06-09 2016-12-15 Danisco Us Inc Low-density enzyme-containing particles
US20200040283A1 (en) 2017-03-31 2020-02-06 Danisco Us Inc Delayed release enzyme formulations for bleach-containing detergents
BR112020012584A2 (pt) 2017-12-21 2020-11-24 Danisco Us Inc. grânulos fundidos a quente contendo enzima que compreendem um dessecante termotolerante
BR112020016068A2 (pt) 2018-02-08 2020-12-08 Danisco Us Inc. Partículas cera termicamente resistente matriz para encapsulamento de enzima
CA3103876C (en) 2018-06-15 2024-02-27 Ecolab Usa Inc. On site generated performic acid compositions for teat treatment
BR112021002549A2 (pt) 2018-08-22 2021-05-04 Ecolab Usa Inc. composição de ácido peroxicarboxílico estabilizada, e, método para reduzir uma população microbiana usando uma composição de ácido peroxicarboxílico estabilizada.
US20210189295A1 (en) 2018-08-30 2021-06-24 Danisco Us Inc Enzyme-containing granules
US12096768B2 (en) 2019-08-07 2024-09-24 Ecolab Usa Inc. Polymeric and solid-supported chelators for stabilization of peracid-containing compositions
CN113433085B (zh) * 2021-06-24 2022-11-29 四川新华西乳业有限公司 一种原料乳中脂肪酶活力的检测方法及其应用
EP4402258A2 (en) 2021-09-13 2024-07-24 Danisco US Inc. Bioactive-containing granules

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3974082A (en) * 1972-08-21 1976-08-10 Colgate-Palmolive Company Bleaching compositions
DE2622607C3 (de) * 1976-05-20 1981-09-03 Siemens AG, 1000 Berlin und 8000 München Selbstzentrierende Steckverbindungsanordnung für Lichtwellenleiter
FR2367295A1 (fr) * 1976-10-05 1978-05-05 Cables De Lyon Geoffroy Delore Procede et disposit
US4186997A (en) * 1977-02-14 1980-02-05 Amp Incorporated Overlap type waveguide connector assembly and method
GB8312185D0 (en) * 1983-05-04 1983-06-08 Unilever Plc Bleaching and cleaning composition
JPS60172230A (ja) * 1984-02-15 1985-09-05 和平興業株式会社 移植用苗床製造装置
GB8514707D0 (en) * 1985-06-11 1985-07-10 Unilever Plc Enzymatic detergent composition
US4707287A (en) * 1985-06-28 1987-11-17 The Procter & Gamble Company Dry bleach stable enzyme composition
ATE72579T1 (de) * 1985-08-21 1992-02-15 Clorox Co Stabiles persaeurebleichmittel.
AU603101B2 (en) * 1986-06-09 1990-11-08 Clorox Company, The Enzymatic perhydrolysis system and method of use for bleaching
US5091988A (en) * 1991-04-12 1992-02-25 At&T Bell Laboratories Article for connecting optical fibers

Also Published As

Publication number Publication date
US5030240A (en) 1991-07-09
EP0268456A3 (en) 1989-04-26
ES2030075T3 (es) 1992-10-16
TR23330A (tr) 1989-11-08
EP0268456B1 (en) 1992-01-15
GR3004391T3 (es) 1993-03-31
JP3077700B2 (ja) 2000-08-14
JPS63148988A (ja) 1988-06-21
DE3776089D1 (de) 1992-02-27
EP0268456A2 (en) 1988-05-25
ATE71653T1 (de) 1992-02-15
MX166926B (es) 1993-02-15
AU599436B2 (en) 1990-07-19
AU8134087A (en) 1988-05-26

Similar Documents

Publication Publication Date Title
AR245953A1 (es) Sistema de perhidrolisis de enzimatico para generacion in situ de peracido y procedimiento para blanquear materiales con el mismo.
ES2087864T3 (es) Sistema de blanqueado enzimatico por un peracido con una enzima modificada.
ATE207964T1 (de) Produktion von ammonium-acrylat
NO920248L (no) Enzymatisk behandling av en kjemisk lignocellulosemasse
ES2021360B3 (es) Sistema de hidrólisis enzimática y método de uso para blanquear.
NO850676L (no) Fremgangsmaate for fremstilling av 6-hydroksynikotinsyre
BR8506226A (pt) Processo para aperfeicoar a filtrabilidade de um caldo microbial
ES543861A0 (es) Un procedimiento para convertir enzimaticamente un polisaca-rido en un monosacarido o en uno o mas polisacaridos de me- nor peso molecular
ES478533A1 (es) Un procedimiento para eliminar melamina de liquidos que con-tienen melamina.
KR840007969A (ko) 두유의 제조방법
KR900003375A (ko) L(-)-테트라히드로폴산의 제조방법
ES2053475T3 (es) Una 3-alfa-hidroxiesteroide oxidasa y analisis cuantitativo de una 3-alfa-hidroxiesteroide.
KR910008138A (ko) 효소법에 의한 l-세린의 제조법
KR950011613A (ko) 고정화 효소의 제조 방법 및 이를 사용하여 히단토인 유도체로 부터 n-카르바모일-d-아미노산을 제조하는 방법
KR890002492A (ko) 펄프 고해 방법
EP0365029A3 (en) Method of systhesizing optically active beta-halolactic acid or glycidic acid
KR910008143A (ko) 수분 활성도 억제 방법에 의한 세팔렉신 제조 방법
DE3775866D1 (de) Verfahren zur durchfuehrung enzymatischer oxidationen.
KR930700670A (ko) 약 제
ATE26594T1 (de) Verfahren zur behandlung von glukose vor ihrer enzymatischen isomerisierung zu fruktose.