AR245449A1 - Procedimiento para obtener nuevos derivados de la benzoxazina. - Google Patents
Procedimiento para obtener nuevos derivados de la benzoxazina.Info
- Publication number
- AR245449A1 AR245449A1 AR89315528A AR31552889A AR245449A1 AR 245449 A1 AR245449 A1 AR 245449A1 AR 89315528 A AR89315528 A AR 89315528A AR 31552889 A AR31552889 A AR 31552889A AR 245449 A1 AR245449 A1 AR 245449A1
- Authority
- AR
- Argentina
- Prior art keywords
- oxo
- formula
- benzoxazine
- a2nco
- aooc
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
PROCEDIMIENTO PARA OBTENER NUEVOS DERIVADOS DE LA BENZOXAZINA, DE FORMULA (I), EN LA QUE R1 Y R2 SON H O A, Y TAMBIEN R1 JUNTO CON R2 SON ALQUILENO (C3-6), R3 ES PIRIDIL-Z-, PIRIDAZINIL-Z-, PIRIMIDINIL-Z-, PIRAZINIL-Z-, OXO DIHIDROPIRIDIL-(ZN)-, OXO-DIHIDROPIRIDAZINIL-(ZN)-, OXO- DIHIDROPIRIDIMIDINIL-(ZN)-, OXO-DIHIDROPIRAZINIL-(ZN)- U OXO- DIHIDROPIRROLIL-(ZN)-, SUSTITUIDO O NO UNA O DOSVECES CON A, F, CL, BR, I, OH, OA, OAC, SH, NO2, ACNH, HOOC Y/O AOOC, PUDIENDO ESTAR PARCIAL O TOTALMENTE HIDROGENADOS LOS RESTOS QUE NO SE ENCUENTRAN UNIDOS A TRAVES DE Z AL NUCLEO DE LA BENZOXAZINA;R4 Y R5 SON ENTRE OTROS H, A, HO, AO, CHO, ACO, ACS, HOOC, AOOC, AO-CS, ACOO, A-CS-O, NO2, NH2, NHA, NA2, CN, HALO, CF3, ASO, ASO2, AO-SO, AO-SO2, ACNH, AO-CO-NH, A2NSO,H2NSO2, A2NSO2, H2NCO, HANCO,A2NCO, A2NCO, H2NCS, HANCS,A2NCS,ASONH, ASO2NH, AOSONH, AOSO2HN, NITROALQUILO, CIANOALQUILO (C1-16), A-C(=NOH) O A-C(=NNH2); Z ES O, S O NH; N VALE 0 O 1; A ES ALQUILO, Y AC ES ALCANOILOO AROILO, SIENDO R3 2- OXOPIRROLIDINILO O 2-OXOPIPERIDINILO SIMULTANEAMENTE CON R4 CON EL SIGNIFICADO DE HIDROGENO, SOLAMENTE EN LOS CASOS EN QUE R5 DIFIERA DE H,A,AO,F,CL, BR O I, DONDE SE HACE REACCIONAR UNA BENZOXAZINA DE FORMULA (II) EN LA QUE E ES CL, BR, I O UN GRUPO DE OH ESTERIFICADO, REACTIVO, CON UN COMPUESTO DE FORMULA (III): R3 - H.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3840011A DE3840011A1 (de) | 1988-11-26 | 1988-11-26 | Benzoxazinderivate |
Publications (1)
Publication Number | Publication Date |
---|---|
AR245449A1 true AR245449A1 (es) | 1994-01-31 |
Family
ID=6367979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AR89315528A AR245449A1 (es) | 1988-11-26 | 1989-11-24 | Procedimiento para obtener nuevos derivados de la benzoxazina. |
Country Status (19)
Country | Link |
---|---|
US (1) | US5036068A (es) |
EP (1) | EP0371312B1 (es) |
JP (1) | JPH02193995A (es) |
KR (1) | KR900007835A (es) |
AR (1) | AR245449A1 (es) |
AT (1) | ATE108789T1 (es) |
AU (1) | AU625697B2 (es) |
CA (1) | CA2003772A1 (es) |
DE (2) | DE3840011A1 (es) |
DK (1) | DK594689A (es) |
ES (1) | ES2057067T3 (es) |
FI (1) | FI895624A0 (es) |
HU (1) | HUT56097A (es) |
IE (1) | IE63766B1 (es) |
IL (1) | IL92419A0 (es) |
NO (1) | NO894707L (es) |
NZ (1) | NZ231518A (es) |
PT (1) | PT92397B (es) |
ZA (1) | ZA899005B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0303172A3 (de) * | 1987-08-14 | 1991-05-15 | F. Hoffmann-La Roche Ag | Oxyimino-Cephalosporine |
DE4027592A1 (de) * | 1990-08-31 | 1992-03-05 | Beiersdorf Ag | Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen |
CN1060467A (zh) * | 1990-09-25 | 1992-04-22 | 武田药品工业株式会社 | 1,3-苯并嗪衍生物、其生产方法和用途 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS54118120A (en) * | 1978-03-07 | 1979-09-13 | Riyouma Shisutemuzu Kk | Method of processing clerk |
JPS5643281A (en) * | 1979-09-14 | 1981-04-21 | Sankyo Co Ltd | 1,3-benzoxazine derivative and its preparation |
JPS57130979A (en) * | 1981-02-09 | 1982-08-13 | Sankyo Co Ltd | 4-amino-1,3-benzoxazine derivative and its preparation |
US4816454A (en) * | 1984-09-21 | 1989-03-28 | Cassella Aktiengesellschaft | 4,5-dihydro-3(2H)-pyridazinones and their pharmacological use |
JPS63284547A (ja) * | 1987-05-15 | 1988-11-21 | Konica Corp | 有機着色物質の光褪色防止方法 |
-
1988
- 1988-11-26 DE DE3840011A patent/DE3840011A1/de not_active Withdrawn
-
1989
- 1989-11-14 EP EP89121067A patent/EP0371312B1/de not_active Expired - Lifetime
- 1989-11-14 DE DE58908070T patent/DE58908070D1/de not_active Expired - Fee Related
- 1989-11-14 AT AT89121067T patent/ATE108789T1/de not_active IP Right Cessation
- 1989-11-14 ES ES89121067T patent/ES2057067T3/es not_active Expired - Lifetime
- 1989-11-22 US US07/440,622 patent/US5036068A/en not_active Expired - Fee Related
- 1989-11-22 JP JP1302300A patent/JPH02193995A/ja active Pending
- 1989-11-22 AU AU45465/89A patent/AU625697B2/en not_active Ceased
- 1989-11-23 IL IL92419A patent/IL92419A0/xx not_active IP Right Cessation
- 1989-11-23 PT PT92397A patent/PT92397B/pt not_active IP Right Cessation
- 1989-11-24 IE IE376189A patent/IE63766B1/en not_active IP Right Cessation
- 1989-11-24 AR AR89315528A patent/AR245449A1/es active
- 1989-11-24 HU HU896172A patent/HUT56097A/hu unknown
- 1989-11-24 NO NO89894707A patent/NO894707L/no unknown
- 1989-11-24 DK DK594689A patent/DK594689A/da not_active Application Discontinuation
- 1989-11-24 FI FI895624A patent/FI895624A0/fi not_active Application Discontinuation
- 1989-11-24 CA CA002003772A patent/CA2003772A1/en not_active Abandoned
- 1989-11-24 ZA ZA899005A patent/ZA899005B/xx unknown
- 1989-11-24 NZ NZ231518A patent/NZ231518A/en unknown
- 1989-11-25 KR KR1019890017188A patent/KR900007835A/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE3840011A1 (de) | 1990-05-31 |
DK594689D0 (da) | 1989-11-24 |
KR900007835A (ko) | 1990-06-02 |
CA2003772A1 (en) | 1990-05-26 |
HUT56097A (en) | 1991-07-29 |
IE63766B1 (en) | 1995-06-14 |
AU4546589A (en) | 1990-05-31 |
EP0371312A1 (de) | 1990-06-06 |
NZ231518A (en) | 1991-07-26 |
ATE108789T1 (de) | 1994-08-15 |
DE58908070D1 (de) | 1994-08-25 |
ZA899005B (en) | 1990-08-29 |
EP0371312B1 (de) | 1994-07-20 |
IL92419A0 (en) | 1990-07-26 |
NO894707D0 (no) | 1989-11-24 |
JPH02193995A (ja) | 1990-07-31 |
PT92397B (pt) | 1995-08-09 |
US5036068A (en) | 1991-07-30 |
DK594689A (da) | 1990-05-27 |
IE893761L (en) | 1990-05-26 |
ES2057067T3 (es) | 1994-10-16 |
FI895624A0 (fi) | 1989-11-24 |
HU896172D0 (en) | 1990-02-28 |
NO894707L (no) | 1990-05-28 |
PT92397A (pt) | 1990-05-31 |
AU625697B2 (en) | 1992-07-16 |
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