AR243493A1 - Procedimiento para preparar (e)-2-(p-fluorfenetil)-3-fluoralilamina y sus sales farmaceuticamente aceptables, util como inhibidor de mao-b irreversible y activado por enzimas. - Google Patents

Procedimiento para preparar (e)-2-(p-fluorfenetil)-3-fluoralilamina y sus sales farmaceuticamente aceptables, util como inhibidor de mao-b irreversible y activado por enzimas.

Info

Publication number
AR243493A1
AR243493A1 AR88311087A AR31108788A AR243493A1 AR 243493 A1 AR243493 A1 AR 243493A1 AR 88311087 A AR88311087 A AR 88311087A AR 31108788 A AR31108788 A AR 31108788A AR 243493 A1 AR243493 A1 AR 243493A1
Authority
AR
Argentina
Prior art keywords
fluoroallylamine
fluorophenethyl
Prior art date
Application number
AR88311087A
Other languages
English (en)
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of AR243493A1 publication Critical patent/AR243493A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
AR88311087A 1987-06-16 1988-06-10 Procedimiento para preparar (e)-2-(p-fluorfenetil)-3-fluoralilamina y sus sales farmaceuticamente aceptables, util como inhibidor de mao-b irreversible y activado por enzimas. AR243493A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6275887A 1987-06-16 1987-06-16

Publications (1)

Publication Number Publication Date
AR243493A1 true AR243493A1 (es) 1993-08-31

Family

ID=22044602

Family Applications (1)

Application Number Title Priority Date Filing Date
AR88311087A AR243493A1 (es) 1987-06-16 1988-06-10 Procedimiento para preparar (e)-2-(p-fluorfenetil)-3-fluoralilamina y sus sales farmaceuticamente aceptables, util como inhibidor de mao-b irreversible y activado por enzimas.

Country Status (16)

Country Link
EP (1) EP0295604A1 (es)
JP (1) JP2511293B2 (es)
KR (1) KR970000142B1 (es)
CN (1) CN1031075A (es)
AR (1) AR243493A1 (es)
AU (1) AU612655B2 (es)
CA (1) CA1335897C (es)
DK (1) DK325788A (es)
FI (1) FI90658C (es)
HU (1) HU202823B (es)
IL (1) IL86746A0 (es)
NO (1) NO167381C (es)
NZ (1) NZ224982A (es)
PH (1) PH24012A (es)
PT (1) PT87732B (es)
ZA (1) ZA884183B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4055593A (en) * 1992-05-15 1993-12-13 University Of Saskatchewan Method for preventing endothelium damage in mammals and for alleviating pain associated with gout and arthritis
KR950701518A (ko) * 1992-05-27 1995-04-28 스티븐 엘. 네스비트 알쯔하이머 질환의 치료에 있어서 (E)-2-(p-플로오로펜에틸)-3-플루오로알릴아민의 용도(Use of (E)-2-(p-fluorophenethyl)-3-fluoroallylamine in the treatmet of Alzheimer's disease)
US5599986A (en) * 1994-09-29 1997-02-04 Hoechst Marion Roussel Inc. Process for the preparation of alkali metal salts of diformylamide
US5488188A (en) * 1994-09-29 1996-01-30 Merrell Dow Pharmaceuticals Inc. Process for the preparation of (E)-1-amino-2-(fluoromethylene)-4-(p-fluorophenyl)butane, novel processes for preparing an intermediate thereof, and novel intermediates thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4454158A (en) * 1981-06-01 1984-06-12 Merrell Toraude Et Compagnie Allyl amine MAO inhibitors
ES2033233T3 (es) * 1985-12-05 1993-03-16 Merrell Dow Pharmaceuticals Inc. Un procedimiento para preparar una fluoralilamina.

Also Published As

Publication number Publication date
PH24012A (en) 1990-02-09
CA1335897C (en) 1995-06-13
FI90658B (fi) 1993-11-30
AU612655B2 (en) 1991-07-18
NO882655D0 (no) 1988-06-15
DK325788D0 (da) 1988-06-15
PT87732A (pt) 1988-07-01
DK325788A (da) 1988-12-17
CN1031075A (zh) 1989-02-15
PT87732B (pt) 1992-10-30
IL86746A0 (en) 1988-11-30
FI882836A (fi) 1988-12-17
NO167381B (no) 1991-07-22
KR970000142B1 (ko) 1997-01-04
FI90658C (fi) 1994-03-10
JPS6416752A (en) 1989-01-20
NZ224982A (en) 1990-08-28
HU202823B (en) 1991-04-29
HUT51232A (en) 1990-04-28
KR890000399A (ko) 1989-03-14
NO882655L (no) 1988-12-19
FI882836A0 (fi) 1988-06-14
ZA884183B (en) 1989-02-22
NO167381C (no) 1991-10-30
AU1762988A (en) 1988-12-22
EP0295604A1 (en) 1988-12-21
JP2511293B2 (ja) 1996-06-26

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