AR227567A1 - Procedimiento para la produccion de nuevos derivados de 2-(4-aminoalcoxi-fenil)-3,4-dihidro-quinazolin-4-onas y 2-(4-aminoalcoxi-fenil)-3,4-dihidro-pirido(2,3-e)pirimidin-4-onas - Google Patents

Procedimiento para la produccion de nuevos derivados de 2-(4-aminoalcoxi-fenil)-3,4-dihidro-quinazolin-4-onas y 2-(4-aminoalcoxi-fenil)-3,4-dihidro-pirido(2,3-e)pirimidin-4-onas

Info

Publication number
AR227567A1
AR227567A1 AR287776A AR28777681A AR227567A1 AR 227567 A1 AR227567 A1 AR 227567A1 AR 287776 A AR287776 A AR 287776A AR 28777681 A AR28777681 A AR 28777681A AR 227567 A1 AR227567 A1 AR 227567A1
Authority
AR
Argentina
Prior art keywords
aminoalcoxi
dihidro
fenil
onas
pirido
Prior art date
Application number
AR287776A
Other languages
English (en)
Spanish (es)
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19803046871 external-priority patent/DE3046871A1/de
Priority claimed from DE19813115447 external-priority patent/DE3115447A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Application granted granted Critical
Publication of AR227567A1 publication Critical patent/AR227567A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • C07D239/91Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/201,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AR287776A 1980-12-12 1981-12-11 Procedimiento para la produccion de nuevos derivados de 2-(4-aminoalcoxi-fenil)-3,4-dihidro-quinazolin-4-onas y 2-(4-aminoalcoxi-fenil)-3,4-dihidro-pirido(2,3-e)pirimidin-4-onas AR227567A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19803046871 DE3046871A1 (de) 1980-12-12 1980-12-12 Neue chinazolinone, ihre herstellung und ihre verwendung als arzneimittel
DE19813115447 DE3115447A1 (de) 1981-04-16 1981-04-16 Neue pyrimidinone, ihre herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
AR227567A1 true AR227567A1 (es) 1982-11-15

Family

ID=25789685

Family Applications (1)

Application Number Title Priority Date Filing Date
AR287776A AR227567A1 (es) 1980-12-12 1981-12-11 Procedimiento para la produccion de nuevos derivados de 2-(4-aminoalcoxi-fenil)-3,4-dihidro-quinazolin-4-onas y 2-(4-aminoalcoxi-fenil)-3,4-dihidro-pirido(2,3-e)pirimidin-4-onas

Country Status (22)

Country Link
US (1) US4379788A (el)
EP (1) EP0054132B1 (el)
AR (1) AR227567A1 (el)
AU (1) AU543568B2 (el)
CA (1) CA1217767A (el)
CS (1) CS227024B2 (el)
DD (1) DD208151A5 (el)
DE (1) DE3166627D1 (el)
DK (1) DK525481A (el)
ES (2) ES8207156A1 (el)
FI (1) FI813971L (el)
GB (1) GB2090249B (el)
GR (1) GR76952B (el)
HU (1) HU187384B (el)
IL (1) IL64504A (el)
MY (1) MY8700562A (el)
NO (1) NO814239L (el)
NZ (1) NZ199254A (el)
PH (1) PH18930A (el)
PL (1) PL135330B1 (el)
PT (1) PT74116B (el)
SU (1) SU1056900A3 (el)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4460589A (en) * 1980-10-03 1984-07-17 The Upjohn Company Process for treating hypertension
US4379778A (en) * 1980-10-10 1983-04-12 Air Products And Chemicals, Inc. Hydrogen peroxide synthesis
DE3428476A1 (de) * 1984-08-02 1986-02-13 Basf Ag, 6700 Ludwigshafen 4h-pyrido(2,3-d)(1,3)oxazin-4-on-derivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
DE3631294A1 (de) * 1986-09-13 1988-03-24 Thomae Gmbh Dr K Neue synergistische kombination bestehend aus einem phosphodiesterase-hemmer und einem thromboxan-a(pfeil abwaerts)2(pfeil abwaerts)-antagonisten und deren verwendung bzw. herstellung
US5037980A (en) * 1988-04-18 1991-08-06 American Cyanamid Company Phenyl imidazo[1,2-a]pyrimidines
GB8928346D0 (en) * 1989-12-15 1990-02-21 Smith Kline French Lab Chemical compounds
GB9126260D0 (en) * 1991-12-11 1992-02-12 Pfizer Ltd Therapeutic agents
GB9404485D0 (en) 1994-03-09 1994-04-20 Cancer Res Campaign Tech Benzamide analogues
EP2295436A1 (de) * 1997-11-12 2011-03-16 Bayer Schering Pharma AG 2-Phenyl-substituierte Imidazotriazinone als Phosphodiesterase V Inhibitoren
WO2000029389A1 (fr) * 1998-11-18 2000-05-25 Elena Alexandrovna Izaxon 6-(3-carboxymethylphenyl)-amino-uracyle ayant une action biologique
US20040102324A1 (en) 2002-02-28 2004-05-27 Annis Gary David Heterocyclic diamide invertebrate pest control agents
US6642244B2 (en) 2001-03-16 2003-11-04 Bristol-Myers Squibb Co. Pyrazolopyridopyrimidine inhibitors of cGMP phosphodiesterase
CN1518447A (zh) * 2001-04-23 2004-08-04 �������Ǵ�ѧר������� 作为抗血管生成剂的新的苯邻二甲酰亚胺模拟物的合成和评估
PL363679A1 (en) * 2001-05-09 2004-11-29 Bayer Healthcare Ag Novel use of 2-phenyl-substituted imidazotriazinones
DE10232113A1 (de) 2002-07-16 2004-01-29 Bayer Ag Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel
WO2005065183A2 (en) * 2003-12-19 2005-07-21 Merck & Co., Inc. Mitotic kinesin inhibitors
SE0401342D0 (sv) * 2004-05-25 2004-05-25 Astrazeneca Ab Therapeutic compounds
SE0401345D0 (sv) * 2004-05-25 2004-05-25 Astrazeneca Ab Therapeutic compounds: Pyridine as scaffold
EP1757594A4 (en) * 2004-05-31 2007-12-12 Banyu Pharma Co Ltd quinazoline derivative
DE102005001989A1 (de) * 2005-01-15 2006-07-20 Bayer Healthcare Ag Intravenöse Formulierungen von PDE-Inhibitoren
DE102005009241A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit kontrollierter Bioverfügbarkeit
DE102005009240A1 (de) * 2005-03-01 2006-09-07 Bayer Healthcare Ag Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften
EP1931797A2 (en) * 2005-09-29 2008-06-18 Bayer HealthCare AG Pde inhibitors and combinations thereof for the treatment of urological disorders
AU2007303846B2 (en) * 2006-10-04 2011-03-10 Pfizer Products Inc. Pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as calcium receptor antagonists
KR20100029762A (ko) * 2007-06-13 2010-03-17 바이엘 쉐링 파마 악티엔게젤샤프트 청력 장애 치료용 pde 억제제
CN101531638B (zh) * 2008-03-13 2011-12-28 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
CN102098918A (zh) * 2008-05-13 2011-06-15 帕纳德制药公司 用于治疗癌症和神经退行性疾病的生物活性化合物
CN101628913B (zh) 2008-07-18 2013-01-23 中国科学院广州生物医药与健康研究院 用作雌激素相关受体调节剂的化合物及其应用
WO2014048532A1 (en) * 2012-09-26 2014-04-03 Merck Patent Gmbh Quinazolinone derivatives as parp inhibitors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265697A (en) * 1964-09-04 1966-08-09 Shulton Inc 2-p-dialkylaminoalkoxyphenyl-2, 3-dihydro-4 (1h)-quinazolinones and their derivatives
DE1939109A1 (de) * 1968-08-31 1970-03-05 Troponwerke Dinklage & Co 2-Methyl-3-[2-(2-diaethylaminoaethoxy)-phenyl]-chinazolinon-(4) und Verfahren zu seiner Herstellung
US3862191A (en) * 1972-09-27 1975-01-21 Pfizer Pyrido{8 2,3-d{9 pyrimidin-4(3H)-one

Also Published As

Publication number Publication date
DK525481A (da) 1982-06-13
CA1217767A (en) 1987-02-10
ES511835A0 (es) 1983-02-16
GB2090249A (en) 1982-07-07
PT74116A (de) 1982-01-01
DE3166627D1 (en) 1984-11-15
NO814239L (no) 1982-06-14
NZ199254A (en) 1985-02-28
GB2090249B (en) 1984-08-22
CS227024B2 (en) 1984-04-16
MY8700562A (en) 1987-12-31
PT74116B (de) 1983-12-19
ES8304096A1 (es) 1983-02-16
FI813971L (fi) 1982-06-13
IL64504A (en) 1985-02-28
PH18930A (en) 1985-11-11
AU7847381A (en) 1982-06-17
EP0054132B1 (de) 1984-10-10
IL64504A0 (en) 1982-03-31
PL135330B1 (en) 1985-10-31
HU187384B (en) 1985-12-28
ES507761A0 (es) 1982-09-01
GR76952B (el) 1984-09-04
PL234175A1 (el) 1982-08-16
SU1056900A3 (ru) 1983-11-23
AU543568B2 (en) 1985-04-26
ES8207156A1 (es) 1982-09-01
DD208151A5 (de) 1984-03-28
US4379788A (en) 1983-04-12
EP0054132A1 (de) 1982-06-23

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