AR227417A1 - Procedimiento para la obtencion de mucopolisacaridos que poseen actividad anti-xa(yin-wessler)elevada,con una relacion de su titulo yin-wissler a su titulo usp de al menos igual a 2 - Google Patents

Procedimiento para la obtencion de mucopolisacaridos que poseen actividad anti-xa(yin-wessler)elevada,con una relacion de su titulo yin-wissler a su titulo usp de al menos igual a 2

Info

Publication number
AR227417A1
AR227417A1 AR284697A AR28469781A AR227417A1 AR 227417 A1 AR227417 A1 AR 227417A1 AR 284697 A AR284697 A AR 284697A AR 28469781 A AR28469781 A AR 28469781A AR 227417 A1 AR227417 A1 AR 227417A1
Authority
AR
Argentina
Prior art keywords
yin
title
mucopolisacarides
wissler
wessler
Prior art date
Application number
AR284697A
Other languages
English (en)
Original Assignee
Choay Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9239907&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR227417(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Choay Sa filed Critical Choay Sa
Application granted granted Critical
Publication of AR227417A1 publication Critical patent/AR227417A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AR284697A 1980-03-20 1981-03-20 Procedimiento para la obtencion de mucopolisacaridos que poseen actividad anti-xa(yin-wessler)elevada,con una relacion de su titulo yin-wissler a su titulo usp de al menos igual a 2 AR227417A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8006282A FR2478646A2 (fr) 1980-03-20 1980-03-20 Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir

Publications (1)

Publication Number Publication Date
AR227417A1 true AR227417A1 (es) 1982-10-29

Family

ID=9239907

Family Applications (1)

Application Number Title Priority Date Filing Date
AR284697A AR227417A1 (es) 1980-03-20 1981-03-20 Procedimiento para la obtencion de mucopolisacaridos que poseen actividad anti-xa(yin-wessler)elevada,con una relacion de su titulo yin-wissler a su titulo usp de al menos igual a 2

Country Status (20)

Country Link
US (1) US4686288A (es)
EP (1) EP0037319B2 (es)
JP (1) JPH0231081B2 (es)
AR (1) AR227417A1 (es)
AT (1) ATE26450T1 (es)
CA (1) CA1207759A (es)
CS (1) CS222245B2 (es)
DD (1) DD157561A5 (es)
DE (1) DE3176086D1 (es)
DK (1) DK172877B1 (es)
ES (1) ES8201596A1 (es)
FR (1) FR2478646A2 (es)
HU (1) HU188657B (es)
IE (1) IE52951B1 (es)
IL (1) IL62424A (es)
PL (1) PL135948B1 (es)
SU (1) SU1658820A3 (es)
UA (1) UA5934A1 (es)
WO (1) WO1981002737A1 (es)
YU (1) YU43008B (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2503714B1 (fr) * 1981-04-10 1986-11-21 Choay Sa Procede d'obtention de mucopolysaccharides biologiquement actifs, de purete elevee, par depolymerisation de l'heparine
FR2553287B1 (fr) * 1983-10-18 1986-09-12 Choay Sa Compositions a base de mucopolysaccharides ou d'oligosaccharides, notamment a base de fractions ou fragments d'heparine, appropriees au traitement de desordres de la proliferation cellulaire
CA1260461A (fr) * 1984-10-18 1989-09-26 Jean-Claude Lormeau Procede de preparation de compositions de mucopolysaccharides dotes d'une activite antithrombotique elevee
FR2572080B1 (fr) * 1984-10-18 1987-06-26 Dropic Procede de preparation de compositions de mucopolysaccharides dotees d'une activite antithrombotique elevee, les compositions obtenues et leur application en tant que medicaments
FR2584606A1 (fr) * 1985-07-12 1987-01-16 Dropic Utilisation de poly- et oligosaccharides pour l'obtention de medicaments actifs dans les pathologies du tissu conjonctif
US4788307A (en) * 1986-04-30 1988-11-29 Choay S.A. Oligosaccharidic fractions devoid or practically devoid of antithrombotic activity
US4879282A (en) * 1987-03-17 1989-11-07 Saliba Jr Michael J Medical application for heparin and related molecules
IT1230582B (it) 1988-10-21 1991-10-28 Opocrin S P A Lab Farmabiologi Oliogosaccaridi di dermatan solfato ed eparina aventi attivita' antiaterosclerotica
JP2871822B2 (ja) * 1989-08-29 1999-03-17 玉造株式会社 末端に２，５―アンヒドロマンニトール基または２，５―アンヒドロマンノース基を有するキチン・キトサンオリゴマーおよびその製造方法
AU7681091A (en) * 1990-04-05 1991-10-30 John R Hoidal Method and medicament for prevention or medication of human leucocyte elastase-mediated pulmonary diseases
US5824658A (en) * 1990-09-18 1998-10-20 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
CA2061703C (en) * 1992-02-20 2002-07-02 Rudolf E. Falk Formulations containing hyaluronic acid
US5910489A (en) * 1990-09-18 1999-06-08 Hyal Pharmaceutical Corporation Topical composition containing hyaluronic acid and NSAIDS
US5990096A (en) * 1990-09-18 1999-11-23 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5707973A (en) * 1991-04-23 1998-01-13 Rhone-Poulenc Rorer S.A. Sulfated polysaccharids for treatment or prevention of thromboses
US5977088A (en) * 1991-07-03 1999-11-02 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5792753A (en) * 1991-07-03 1998-08-11 Hyal Pharmaceutical Corporation Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs
US6103704A (en) * 1991-07-03 2000-08-15 Hyal Pharmaceutical Corporation Therapeutic methods using hyaluronic acid
US6218373B1 (en) 1992-02-20 2001-04-17 Hyal Pharmaceutical Corporation Formulations containing hyaluronic acid
US5767106A (en) * 1992-02-21 1998-06-16 Hyal Pharmaceutical Corporation Treatment of disease and conditions associated with macrophage infiltration
FR2691066B1 (fr) * 1992-05-15 1995-06-09 Sanofi Elf Utilisation de glycosaminoglycanes exogenes, de leurs analogues ainsi que de leurs fragments, fractions et derives, pour la preparation de medicaments destines au traitement de thrombopenies.
DE4217917A1 (de) * 1992-05-30 1993-12-02 Job Prof Dr Med Harenberg Immobilisation von chemisch kovalent gebundenem Heparin an Polymere mit Arylresten im Polymer
JP3390477B2 (ja) * 1993-01-25 2003-03-24 生化学工業株式会社 薬剤組成物及びその製造法
FR2704861B1 (fr) * 1993-05-07 1995-07-28 Sanofi Elf Fractions d'héparine purifiées, procédé d'obtention et compositions pharmaceutiques les contenant.
US5646130A (en) * 1995-06-30 1997-07-08 Ocean University Of Oingdao Low molecular weight sulfated polysaccharides and uses thereof
PT946185E (pt) * 1996-11-27 2005-02-28 Aventis Pharm Prod Inc Composicao farmaceutica compreendendo um composto que possui actividade anti-xa e um composto antagonista da agregacao plaquetaria
US5945457A (en) * 1997-10-01 1999-08-31 A.V. Topchiev Institute Of Petrochemical Synthesis, Russian Academy Of Science Process for preparing biologically compatible polymers and their use in medical devices
DE29900874U1 (de) 1999-01-20 1999-07-22 Knoll AG, 67061 Ludwigshafen Organprotektive Lösungen
JP4585072B2 (ja) * 2000-02-29 2010-11-24 扶桑薬品工業株式会社 ヘパリン解重合法、解重合ヘパリン、その誘導体および医薬組成物
US6969705B2 (en) 2000-07-21 2005-11-29 Aventis Pharma S.A. Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
FR2811992B1 (fr) * 2000-07-21 2003-07-04 Aventis Pharma Sa Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant
JP4828795B2 (ja) * 2002-03-11 2011-11-30 モメンタ ファーマシューティカルズ インコーポレイテッド 硫酸化多糖類の分析
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
US7956046B2 (en) 2003-07-24 2011-06-07 Aventis Pharma S.A. Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them
EP1582531A1 (en) 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
EP1792621B1 (en) 2005-11-30 2012-04-04 Istituto di Ricerche Chimiche e Biochimiche "G. Ronzoni" Orally administrable heparin derivatives
US9139876B1 (en) 2007-05-03 2015-09-22 Momenta Pharmacueticals, Inc. Method of analyzing a preparation of a low molecular weight heparin
US8614314B2 (en) 2008-05-30 2013-12-24 Momenta Pharmaceuticals, Inc. Saccharide structures and methods of making and using such structures
EP2526122B1 (en) * 2010-01-19 2020-06-10 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
WO2012115952A1 (en) 2011-02-21 2012-08-30 Momenta Pharmaceuticals, Inc. Evaluating heparin preparations
JP2022540849A (ja) 2019-07-09 2022-09-20 オプティムヴィア、エルエルシー 抗凝固性多糖類の合成方法
EP4182452A4 (en) 2020-07-14 2024-07-31 Optimvia Llc METHOD FOR THE SYNTHESIS OF NON-ANTICOAGULATING HEPARAN SULFATE

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3766167A (en) * 1971-03-26 1973-10-16 Research Corp Orally active anticoagulant
IT1083903B (it) * 1977-08-09 1985-05-25 Lobo Srl Oligo-eteropolisaccaridi con attivita' eparinosimili,procedimento per il loro ottenimento e relative composizioni terapeutiche
US4175182A (en) * 1978-07-03 1979-11-20 Research Corporation Separation of high-activity heparin by affinity chromatography on supported protamine
US4500519A (en) * 1978-11-06 1985-02-19 Choay S.A. Mucopolysaccharides having biological properties, preparation and method of use
FR2440376A1 (fr) * 1978-11-06 1980-05-30 Choay Sa Composition mucopolysaccharidique ayant une activite regulatrice de la coagulation, medicament la contenant et procede pour l'obtenir
SE449753B (sv) * 1978-11-06 1987-05-18 Choay Sa Mukopolysackaridkomposition med reglerande verkan pa koagulation, lekemedel innehallande densamma samt forfarande for framstellning derav
CA1136620A (en) * 1979-01-08 1982-11-30 Ulf P.F. Lindahl Heparin fragments having selective anticoagulation activity
IL61201A (en) * 1979-10-05 1984-09-30 Choay Sa Oligosaccharides having no more than 8 saccharide moieties,their obtention from heparin and pharmaceutical compositions containing them
US4281108A (en) * 1980-01-28 1981-07-28 Hepar Industries, Inc. Process for obtaining low molecular weight heparins endowed with elevated pharmacological properties, and product so obtained
GB2071127B (en) * 1980-02-29 1984-07-25 Italfarmaco Spa Process for the purification of glucosaninoglucans
CA1171375A (en) * 1980-09-15 1984-07-24 Ulf P.F. Lindahl Oligosaccharides having selective anticoagulation activity

Also Published As

Publication number Publication date
WO1981002737A1 (fr) 1981-10-01
HU188657B (en) 1986-05-28
IL62424A0 (en) 1981-05-20
US4686288A (en) 1987-08-11
PL230237A1 (en) 1981-11-13
ES501130A0 (es) 1982-01-16
CA1207759A (en) 1986-07-15
JPH0231081B2 (es) 1990-07-11
IL62424A (en) 1984-12-31
IE52951B1 (en) 1988-04-27
FR2478646B2 (es) 1983-06-24
ES8201596A1 (es) 1982-01-16
PL135948B1 (en) 1986-01-31
UA5934A1 (uk) 1994-12-29
SU1658820A3 (ru) 1991-06-23
DD157561A5 (de) 1982-11-17
CS222245B2 (en) 1983-05-27
IE810632L (en) 1981-09-20
YU43008B (en) 1989-02-28
DK172877B1 (da) 1999-09-06
FR2478646A2 (fr) 1981-09-25
EP0037319B1 (fr) 1987-04-08
DE3176086D1 (en) 1987-05-14
DK511381A (da) 1981-11-18
ATE26450T1 (de) 1987-04-15
EP0037319B2 (fr) 1995-06-28
JPS57500335A (es) 1982-02-25
YU73681A (en) 1983-10-31
EP0037319A1 (fr) 1981-10-07

Similar Documents

Publication Publication Date Title
AR227417A1 (es) Procedimiento para la obtencion de mucopolisacaridos que poseen actividad anti-xa(yin-wessler)elevada,con una relacion de su titulo yin-wissler a su titulo usp de al menos igual a 2
AR240830A1 (es) Procedimiento para preparar derivados de acidos naftiridin quinolin-y benzoxazincarboxilicos.
ES547478A0 (es) Procedimiento para la preparacion de pelicula de celulosa
ES511498A0 (es) Un procedimiento para la preparacion de derivados del 1,2,5-tiadiazol
ES541200A0 (es) Un procedimiento para la preparacion de un derivado de dibenzoilmetano.
MX158194A (es) Procedimiento para la preparacion del sesquihidrato de un derivado de naftiridina
ES543448A0 (es) Un procedimiento para la preparacion de derivados de furano con actividad antiulcerosa
ES502641A0 (es) Un procedimiento para la preparacion de una estructura estratificada.
ES537650A0 (es) Un procedimiento para preparar nuevos derivados de milbemicinas.
MX159635A (es) Procedimiento para la preparacion de peroxidos organicos
ES518189A0 (es) Procedimiento para preparar nuevos derivados de encefalina.
ES549152A0 (es) Procedimiento para preparar nuevas homoproporgilaminas.
ES518710A0 (es) Procedimiento para preparar fenilsulfonilisocianatos sustituidos.
AR227697A1 (es) Procedimiento para la preparacion de 3,4-bis-sustituido 1,2,5,-oxadiazol-2-oxidos
ES500618A0 (es) Procedimiento para la preparacion de 2,3-dicloro-2-trifluo- rometil-1,1,1,3,4,4,5,5,5,-nonafluoropentano
ES523288A0 (es) Procedimiento para preparar un derivado de pirazolpiridina.
ES511058A0 (es) Procedimiento para preparar nuevos derivados de fenoxibencilo.
MX7052E (es) Procedimiento para la preparacion de 2-metoxi-4-amino-5-alquilsulfonil-n-(3-beta-8-azabiciclo-(3,2,1)octil)-benzamidas
ES511067A0 (es) Procedimiento para preparar un derivado de prostaglandina.
ES506245A0 (es) Un procedimiento para la preparacion de una composicion de glucosido de diterpeno.
BR8104773A (pt) Trava de palhetas para conjunto de palhetas de turbina
ES557313A0 (es) Procedimiento para preparar derivados de fenilpirazina
ES509185A0 (es) Procedimiento para la obtencion de esteres de 4-fluor-3-halofenoxibencilo.
ES522904A0 (es) Un metodo para obtener una preparacion farmaceutica que contiene un derivado de 16 beta-etil-17 beta-hidroxi-estrano.
ES522166A0 (es) Procedimiento para la obtencion de sulfonil- y sulfonil-azacicloheptan-2-onas.