AR225878A1 - Nuevos derivados de 3-amino-2-azetidinon-1-((2-halo-acetil o 2-haloetiliden))-acetico,procedimiento para prepararlos y procedimiento para obtener compuestos 3-cefem a partir de dichos derivados - Google Patents

Nuevos derivados de 3-amino-2-azetidinon-1-((2-halo-acetil o 2-haloetiliden))-acetico,procedimiento para prepararlos y procedimiento para obtener compuestos 3-cefem a partir de dichos derivados

Info

Publication number
AR225878A1
AR225878A1 AR262283A AR26228376A AR225878A1 AR 225878 A1 AR225878 A1 AR 225878A1 AR 262283 A AR262283 A AR 262283A AR 26228376 A AR26228376 A AR 26228376A AR 225878 A1 AR225878 A1 AR 225878A1
Authority
AR
Argentina
Prior art keywords
procedure
derivatives
haloetiliden
azetidinon
acetil
Prior art date
Application number
AR262283A
Other languages
English (en)
Spanish (es)
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27457226&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR225878(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP50019612A external-priority patent/JPS5198265A/ja
Priority claimed from JP50022229A external-priority patent/JPS51105051A/ja
Priority claimed from JP50028452A external-priority patent/JPS609516B2/ja
Priority claimed from JP50033808A external-priority patent/JPS5817460B2/ja
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of AR225878A1 publication Critical patent/AR225878A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
AR262283A 1975-02-17 1976-02-17 Nuevos derivados de 3-amino-2-azetidinon-1-((2-halo-acetil o 2-haloetiliden))-acetico,procedimiento para prepararlos y procedimiento para obtener compuestos 3-cefem a partir de dichos derivados AR225878A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP50019612A JPS5198265A (bg) 1975-02-17 1975-02-17
JP50022229A JPS51105051A (bg) 1975-02-21 1975-02-21
JP50028452A JPS609516B2 (ja) 1975-03-07 1975-03-07 セフエム骨格の環化製法
JP50033808A JPS5817460B2 (ja) 1975-03-20 1975-03-20 チアゾリンカンノ カイカンホウホウ

Publications (1)

Publication Number Publication Date
AR225878A1 true AR225878A1 (es) 1982-05-14

Family

ID=27457226

Family Applications (1)

Application Number Title Priority Date Filing Date
AR262283A AR225878A1 (es) 1975-02-17 1976-02-17 Nuevos derivados de 3-amino-2-azetidinon-1-((2-halo-acetil o 2-haloetiliden))-acetico,procedimiento para prepararlos y procedimiento para obtener compuestos 3-cefem a partir de dichos derivados

Country Status (24)

Country Link
US (4) US4079181A (bg)
AR (1) AR225878A1 (bg)
AU (1) AU508160B2 (bg)
BE (1) BE838656A (bg)
BG (5) BG24949A3 (bg)
CA (5) CA1136132A (bg)
CH (5) CH627160A5 (bg)
DD (5) DD127902A5 (bg)
DE (1) DE2606278A1 (bg)
DK (1) DK156575C (bg)
ES (1) ES445250A1 (bg)
FR (1) FR2334669A1 (bg)
GB (3) GB1548641A (bg)
GR (1) GR60437B (bg)
IE (1) IE42479B1 (bg)
IL (5) IL49048A (bg)
MX (1) MX3818E (bg)
NL (1) NL190721C (bg)
NZ (1) NZ180037A (bg)
PH (1) PH18022A (bg)
PT (1) PT64806B (bg)
RO (4) RO68460A (bg)
SE (4) SE421691B (bg)
YU (5) YU40272B (bg)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4550162A (en) * 1975-02-20 1985-10-29 Ciba-Geigy Corporation Process for the manufacture of enol derivatives
US4579684A (en) * 1975-02-20 1986-04-01 Ciba-Geigy Corporation Process for the manufacture of enol derivatives
GB1543048A (en) * 1976-02-04 1979-03-28 Beecham Group Ltd 4-mercapto-3-phenoxyacetamido-2-azetidinone
US4271305A (en) * 1979-02-01 1981-06-02 Eli Lilly And Company Thiazolinoazetidinones and process therefor
JPS55133355A (en) * 1979-04-03 1980-10-17 Shionogi & Co Ltd Inversion of 3-amino group of beta-lactam ring
US4518531A (en) * 1979-04-30 1985-05-21 Eli Lilly And Company Allylic chlorination process and compounds prepared thereby
FR2455604A1 (fr) * 1979-04-30 1980-11-28 Lilly Co Eli Nouveaux derives de thiazolino-azetidinones et leur preparation
CA1148938A (en) * 1979-05-08 1983-06-28 John R. Corfield Preparation of cephalosporins and intermediates employed therein
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
EP0065488B1 (de) * 1981-05-19 1985-08-14 Ciba-Geigy Ag Verfahren zur Herstellung von 4-Thio-azetidinon-Verbindungen
FR2511376A1 (fr) * 1981-08-17 1983-02-18 Rhone Poulenc Sante Nouveaux derives de la cephalosporine et leur prepration
JPS5832884A (ja) * 1981-08-20 1983-02-25 Otsuka Chem Co Ltd ３−エキソメチレンセフアム誘導体の製造方法
JPS59101485A (ja) * 1982-11-29 1984-06-12 Otsuka Chem Co Ltd アセチジノン誘導体
US4533497A (en) * 1982-12-27 1985-08-06 Eli Lilly And Company N-ethylidene azetidinones
KR850000291B1 (ko) * 1983-02-07 1985-03-16 한국과학기술원 3-메틸렌 세팜 화합물의 제조방법
JPS59164771A (ja) * 1983-03-10 1984-09-17 Otsuka Chem Co Ltd 塩素化アゼチジノン誘導体の製造方法
EP0133670A3 (de) * 1983-08-09 1985-12-18 Bayer Ag Verfahren zur Herstellung von 7-Acylamino-3-hydrocy-cephem-4-carbonsäuren und 7-Acylamino-3-hydroxy-1-de-thia-1-oxacephem-4-carbonsäuren
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren
JP3007986B2 (ja) * 1990-03-02 2000-02-14 大塚化学株式会社 β―ラクタム誘導体の製法
EP0445822B1 (en) * 1990-03-08 1997-06-04 Otsuka Kagaku Kabushiki Kaisha Thiazolinoazetidinone derivative and process for preparing 2-exo-methylene-penam derivative thereform
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
IT1277048B1 (it) * 1995-12-06 1997-11-04 3 Exo S R L Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento con
US5986091A (en) * 1996-03-13 1999-11-16 Otsuka Kagaku Kabushiki Kaisha Process for preparation of β-lactam compounds
WO2009049086A1 (en) 2007-10-09 2009-04-16 Larry Sutton Broad spectrum beta-lactamase inhibitors
CN101525341B (zh) * 2009-04-01 2012-07-04 浙江东邦药业有限公司 一种3-羟基头孢化合物的制备方法
JP6403289B2 (ja) 2013-03-12 2018-10-10 グラディウス ファーマシューティカルズ コーポレーションＧｌａｄｉｕｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｃｏｒｐｏｒａｔｉｏｎ 誘導体化３−スチリル−セファロスポリン
CN108727409A (zh) * 2017-04-24 2018-11-02 浙江省化工研究院有限公司 一种3-羟基头孢菌素的制备方法
CN115397807B (zh) * 2020-04-17 2024-08-13 帝斯曼知识产权资产管理有限公司 用于制备取代的烯胺化合物的方法
CN111647638A (zh) * 2020-04-17 2020-09-11 江苏正泰药业有限公司 一种7-anca的制备工艺

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862164A (en) * 1971-02-03 1975-01-21 Lilly Co Eli Thiazolidine azetidinones
GB1457421A (en) * 1973-01-04 1976-12-01 Glaxo Lab Ltd Cepham derivatives
AU498131B2 (en) * 1974-02-26 1979-02-15 Ciba-Geigy Ag Production of cephems by cyclization
JPS5188955A (bg) * 1975-01-30 1976-08-04
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
US4147864A (en) * 1975-02-20 1979-04-03 Ciba-Geigy Corporation Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
JPS5214789A (en) * 1975-07-22 1977-02-03 Shionogi & Co Ltd Process for preparing 3-substiuted cephem compounds by ring closure
US4008230A (en) * 1975-10-29 1977-02-15 Eli Lilly And Company Process for preparing 3-hydroxy cephalosporins
JPS6019315B2 (ja) * 1976-01-23 1985-05-15 塩野義製薬株式会社 アゼチジノン化合物
GB1529913A (en) * 1976-02-04 1978-10-25 Beecham Group Ltd Beta-lactam compounds
US4264597A (en) * 1978-06-06 1981-04-28 Masashi Hashimoto Cephalosporin analogues and processes for the preparation thereof

Also Published As

Publication number Publication date
GB1548641A (en) 1979-07-18
CH627160A5 (en) 1981-12-31
SE444811B (sv) 1986-05-12
DD124986A5 (bg) 1977-03-23
CA1136132A (en) 1982-11-23
SE421691B (sv) 1982-01-25
GB1548642A (en) 1979-07-18
IE42479L (en) 1976-08-17
IL57541A0 (en) 1979-10-31
YU40272B (en) 1985-12-31
GB1548643A (en) 1979-07-18
CA1077936A (en) 1980-05-20
YU173982A (en) 1983-01-21
YU40412B (en) 1985-12-31
NL190721B (nl) 1994-02-16
DD127901A5 (de) 1977-10-19
NZ180037A (en) 1979-11-01
DK156575B (da) 1989-09-11
BG25216A3 (bg) 1978-08-10
DE2606278A1 (de) 1976-08-26
SE7601715L (sv) 1976-08-18
IE42479B1 (en) 1980-08-13
YU174182A (en) 1983-01-21
US4079181A (en) 1978-03-14
US4346218A (en) 1982-08-24
PT64806B (en) 1977-07-07
BE838656A (fr) 1976-06-16
BG27557A4 (bg) 1979-11-12
BG25076A3 (bg) 1978-07-12
CH630074A5 (en) 1982-05-28
YU40411B (en) 1985-12-31
CH628030A5 (en) 1982-02-15
RO74958A (ro) 1980-10-30
CA1095026A (en) 1981-02-03
CH634579A5 (en) 1983-02-15
PH18022A (en) 1985-03-03
RO75006A (ro) 1980-10-30
YU38476A (en) 1983-01-21
DK61976A (da) 1976-08-18
IL56049A0 (en) 1979-01-31
YU173882A (en) 1983-01-21
IL56050A0 (en) 1979-01-31
DD127902A5 (de) 1977-10-19
DE2606278C2 (bg) 1989-05-03
YU40414B (en) 1985-12-31
DD127899A5 (de) 1977-10-19
US4160085A (en) 1979-07-03
FR2334669B1 (bg) 1981-12-31
CA1132547A (en) 1982-09-28
SE7907811L (sv) 1979-09-20
YU174282A (en) 1983-01-21
NL7601613A (nl) 1976-08-19
ES445250A1 (es) 1977-06-16
SE434637B (sv) 1984-08-06
YU40413B (en) 1985-12-31
AU508160B2 (en) 1980-03-13
IL57418A0 (en) 1979-09-30
IL49048A (en) 1981-12-31
BG24949A3 (bg) 1978-06-15
SE7907813L (sv) 1979-09-20
RO74936A (fr) 1980-10-30
DD127900A5 (de) 1977-10-19
US4440683A (en) 1984-04-03
SE7907812L (sv) 1979-09-20
FR2334669A1 (fr) 1977-07-08
MX3818E (es) 1981-07-30
IL49048A0 (en) 1976-04-30
CH628031A5 (en) 1982-02-15
GR60437B (en) 1978-05-26
BG24948A3 (bg) 1978-06-15
RO68460A (ro) 1981-08-17
SE434950B (sv) 1984-08-27
DK156575C (da) 1990-02-05
AU1118176A (en) 1977-08-25
CA1144924A (en) 1983-04-19
NL190721C (nl) 1994-07-18

Similar Documents

Publication Publication Date Title
AR225878A1 (es) Nuevos derivados de 3-amino-2-azetidinon-1-((2-halo-acetil o 2-haloetiliden))-acetico,procedimiento para prepararlos y procedimiento para obtener compuestos 3-cefem a partir de dichos derivados
AR213097A1 (es) Procedimiento para preparar derivados de la 1,4-dihidropirina
NO148712C (no) Fremgangsmaate ved fremstilling av etylidendiacetat
NO142240C (no) Fremgangsmaate ved fremstilling av fiskekjoettekstrakt
MX5119E (es) Procedimiento mejorado para la preparacion de derivados de pirimidona
MX4614E (es) Procedimiento mejorado para la preparacion de derivados de pirimidina
AR225727A1 (es) Procedimiento para la obtencion de nuevos derivados de interfennilen-8-aza-9-dioxotia-11,12-seco-prostaglandina
AR210349A1 (es) Procedimiento para la preparacion de 6-coloro-2(piperacinil)piracina
NO150882C (no) Analogifremgangsmaate ved fremstilling av nye 1,4-benzoksazin-derivater
AR211273A1 (es) Procendimiento de preparacion de nuevas (fenoxi-4-fenil)1-piperazinas
MX3635E (es) Procedimiento para la produccion de compuestos de 3-aciloximetilcefem
AR215871A1 (es) Procedimiento para la fabricacion de (ala-aminoacetil)benceno
DK372177A (da) Fremgangsmaade til fremstilling af thiophenderivater
AR223454A1 (es) Nuevos derivados de cis-4a-fenil-2,3,4,4a,5,6,7,7a-octahidro-1h-2-pirindina;procedimiento para obtenerlos y procedimiento para obtener cis-4a-fenil-octahidro-1h-2-pirindina-1-substituida a partir de dichos derivados
AR208001A1 (es) Procedimiento mejorado para la produccion de uroquinasa
NO146058C (no) Analogifremgangsmaate for fremstilling av substituerte benzamider
AR209835A1 (es) Procedimiento para la preparacion de elastasa pancreatica
NO139555C (no) Fremgangsmaate for fremstilling av fosgen
SE7707621L (sv) Forfarande for framstellning av xyloslosning
SE427929B (sv) Forfarande for framstellning av bens-(f)-2,5-oxazociner
SE7600754L (sv) Forfarande for framstellning av svavelinnehallande oktapeptidderivat
SE420999B (sv) Framstellning av 2,4-diamino-5-bensylpyrimidiner
SE7600847L (sv) Nytt forfarande for framstellning av 8-bromtienotriazolo-1,4-diazepiner
SE418295B (sv) Forfarande for framstellning av 6beta, 17-dihydroxi-7alfa-(legre alkoxikarbonyl-3-oxo-17alfa-pregn-4-en-21-karboxylsyra-gamma-laktoner och dermed beslektade foreningar
SE428016B (sv) Forfarande for framstellning av 6a,10a-cis - hexahydrodibensopyranonderivat