AR211031A1 - Un procedimiento para la preparacion de acido clavulanico y sus sales. - Google Patents

Un procedimiento para la preparacion de acido clavulanico y sus sales.

Info

Publication number
AR211031A1
AR211031A1 AR265082A AR26508276A AR211031A1 AR 211031 A1 AR211031 A1 AR 211031A1 AR 265082 A AR265082 A AR 265082A AR 26508276 A AR26508276 A AR 26508276A AR 211031 A1 AR211031 A1 AR 211031A1
Authority
AR
Argentina
Prior art keywords
salts
procedure
preparation
clavulanic acid
clavulanic
Prior art date
Application number
AR265082A
Other languages
English (en)
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Application granted granted Critical
Publication of AR211031A1 publication Critical patent/AR211031A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/803Physical recovery methods, e.g. chromatography, grinding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/852Klebsiella
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AR265082A 1975-10-13 1976-10-13 Un procedimiento para la preparacion de acido clavulanico y sus sales. AR211031A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB41898/75A GB1563103A (en) 1975-10-13 1975-10-13 Process for the preparation of clavulanic acid

Publications (1)

Publication Number Publication Date
AR211031A1 true AR211031A1 (es) 1977-10-14

Family

ID=10421869

Family Applications (1)

Application Number Title Priority Date Filing Date
AR265082A AR211031A1 (es) 1975-10-13 1976-10-13 Un procedimiento para la preparacion de acido clavulanico y sus sales.

Country Status (26)

Country Link
US (1) US4072569A (es)
JP (1) JPS6057834B2 (es)
AR (1) AR211031A1 (es)
AT (1) AT354624B (es)
AU (1) AU503529B2 (es)
BE (1) BE846933A (es)
CA (1) CA1072471A (es)
CH (1) CH629532A5 (es)
DD (1) DD126930A5 (es)
DE (1) DE2646001A1 (es)
DK (1) DK457576A (es)
ES (1) ES452363A1 (es)
FI (1) FI762909A (es)
FR (1) FR2328045A1 (es)
GB (1) GB1563103A (es)
GR (1) GR61646B (es)
IE (1) IE43801B1 (es)
IL (1) IL50527A (es)
NL (1) NL7611204A (es)
NO (1) NO763474L (es)
NZ (1) NZ182120A (es)
PL (1) PL105494B1 (es)
SE (1) SE434065B (es)
SU (1) SU695565A3 (es)
YU (1) YU251776A (es)
ZA (1) ZA765702B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4155912A (en) 1977-12-14 1979-05-22 Bristol-Myers Company 2-Methylpenem-3-carboxylic acid antibiotics
US4182711A (en) 1978-04-27 1980-01-08 Bristol-Myers Company Antibacterial agents of the β-lactam type
US4282150A (en) 1978-12-18 1981-08-04 Bristol-Myers Company 2,6-Disubstituted penem compounds
US4272437A (en) 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
US4374065A (en) 1979-09-21 1983-02-15 Bristol-Myers Company Antibacterial agents of the β-lactam type
US4378314A (en) 1979-09-21 1983-03-29 Bristol Myers Company Antibacterial agents and metal containing azetidinone intermediates therefore
GB8521516D0 (en) * 1985-08-29 1985-10-02 Beecham Group Plc Compounds
GB9401969D0 (en) * 1994-02-02 1994-03-30 Smithkline Beecham Plc Process
SI9400107A (en) * 1994-03-02 1995-10-31 Lek Tovarna Farmacevtskih New process of the isolation of clavulanic acid and its pharmaceutical salts from fermented broth of streptomyces sp.p 6621 ferm p 2804.
SI9500074A (en) * 1995-03-10 1996-10-31 Lek Tovarna Farmacevtskih Process for preparation of alkani salts of clavulanic acid.
SI9500265A1 (en) 1995-08-28 1997-02-28 Lek Tovarna Farmacevtskih Process for purification of the aqueous fermented broth filtrate of streptomyces sp. p 6621 ferm p 2804 by ultrafiltration
SI9600120A (en) * 1996-04-12 1997-12-31 Lek Tovarna Farmacevtskih New and improved fermentative procedure for the production of clavulanic acid and its salts
AR015825A1 (es) * 1997-05-28 2001-05-30 Gist Brocades Bv Produccion fermentativa de acido clavulanico bajo condiciones controladas de fosfato
US6440708B1 (en) 1998-09-29 2002-08-27 Dsm N.V. Fermentation of clavulanic acid at a controlled level of ammonia
US6979735B1 (en) * 1999-04-01 2005-12-27 Dsm N.V. Agglomerates by crystallization
WO2008065160A1 (en) * 2006-12-01 2008-06-05 Dsm Ip Assets B.V. Process for the production of clavulanic acid
EP2589663A1 (en) 2011-11-04 2013-05-08 LEK Pharmaceuticals d.d. Process for production of clavulanic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5318595B2 (es) * 1972-08-31 1978-06-15
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions

Also Published As

Publication number Publication date
GB1563103A (en) 1980-03-19
NZ182120A (en) 1979-03-16
FR2328045B1 (es) 1980-01-04
IE43801B1 (en) 1981-06-03
SE434065B (sv) 1984-07-02
ES452363A1 (es) 1978-01-01
IL50527A (en) 1979-05-31
NL7611204A (nl) 1977-04-15
FI762909A (es) 1977-04-14
PL105494B1 (pl) 1979-10-31
FR2328045A1 (fr) 1977-05-13
CH629532A5 (de) 1982-04-30
ZA765702B (en) 1977-09-28
SE7611046L (sv) 1977-04-14
IE43801L (en) 1977-04-13
YU251776A (en) 1982-06-30
DD126930A5 (es) 1977-08-24
GR61646B (en) 1978-12-05
IL50527A0 (en) 1976-11-30
AU503529B2 (en) 1979-09-06
DE2646001A1 (de) 1977-04-21
ATA753276A (de) 1979-06-15
AT354624B (de) 1979-01-25
JPS5247991A (en) 1977-04-16
SU695565A3 (ru) 1979-10-30
US4072569A (en) 1978-02-07
JPS6057834B2 (ja) 1985-12-17
CA1072471A (en) 1980-02-26
AU1855576A (en) 1978-04-20
DK457576A (da) 1977-04-14
BE846933A (fr) 1977-04-04
NO763474L (es) 1977-04-14

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