AR125493A1 - Cepa para producir ácido l-glutámico en alta concentración y el procedimiento para producir ácido l-glutámico usando la misma - Google Patents

Cepa para producir ácido l-glutámico en alta concentración y el procedimiento para producir ácido l-glutámico usando la misma

Info

Publication number
AR125493A1
AR125493A1 ARP220101131A ARP220101131A AR125493A1 AR 125493 A1 AR125493 A1 AR 125493A1 AR P220101131 A ARP220101131 A AR P220101131A AR P220101131 A ARP220101131 A AR P220101131A AR 125493 A1 AR125493 A1 AR 125493A1
Authority
AR
Argentina
Prior art keywords
producing
glutamic acid
strain
high concentration
same
Prior art date
Application number
ARP220101131A
Other languages
English (en)
Inventor
Nara Kwon
Hyun Bong
- Lee Jin Nam Ju
Ah Reum Lee
Jung Ok Heo
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of AR125493A1 publication Critical patent/AR125493A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0093Oxidoreductases (1.) acting on CH or CH2 groups (1.17)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/14Glutamic acid; Glutamine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15Corynebacterium
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/04Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
    • C12Y102/04002Oxoglutarate dehydrogenase (succinyl-transferring) (1.2.4.2), i.e. alpha-ketoglutarat dehydrogenase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y117/00Oxidoreductases acting on CH or CH2 groups (1.17)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

La presente solicitud se refiere a una cepa para producir acido L-glutámico en alta concentración y un procedimiento para producir acido L-glutámico usando la misma. Reivindicación 1: Un microorganismo del género Corynebacterium, en el que la proteína VKOR (proteína de la familia vitamina K epóxido reductasa) está desactivada. Reivindicación 9: Un procedimiento para producir ácido L-glutámico, que comprende: cultivar en un medio un microorganismo del género Corynebacterium, en el que la proteína VKOR está desactivada.
ARP220101131A 2021-06-30 2022-04-29 Cepa para producir ácido l-glutámico en alta concentración y el procedimiento para producir ácido l-glutámico usando la misma AR125493A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1020210085738A KR102665227B1 (ko) 2021-06-30 2021-06-30 고농도 l-글루탐산을 생산하기 위한 균주 및 이를 이용한 l-글루탐산 생산방법

Publications (1)

Publication Number Publication Date
AR125493A1 true AR125493A1 (es) 2023-07-19

Family

ID=84690383

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP220101131A AR125493A1 (es) 2021-06-30 2022-04-29 Cepa para producir ácido l-glutámico en alta concentración y el procedimiento para producir ácido l-glutámico usando la misma

Country Status (11)

Country Link
US (1) US20240218381A1 (es)
EP (1) EP4349991A1 (es)
JP (1) JP2024521482A (es)
KR (1) KR102665227B1 (es)
CN (1) CN118369433A (es)
AR (1) AR125493A1 (es)
AU (1) AU2022302574A1 (es)
CA (1) CA3222017A1 (es)
MX (1) MX2023015552A (es)
TW (1) TWI819552B (es)
WO (1) WO2023277307A1 (es)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3220929A (en) 1964-02-10 1965-11-30 Kyowa Hakko Kogyo Kk Microbiological production of amino acid by reductive amination
AU746542B2 (en) 1998-03-18 2002-05-02 Ajinomoto Co., Inc. L-glutamic acid-producing bacterium and method for producing L-glutamic acid
KR100292299B1 (ko) 1999-03-22 2001-06-01 손경식 글루탐산 생산 미생물 및 이를 이용한 글루탐산 생산방법
KR100930842B1 (ko) * 2004-09-10 2009-12-10 아지노모토 가부시키가이샤 L-글루탐산 생산 미생물 및 l-글루탐산의 제조방법
KR100620092B1 (ko) 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
CA2602793C (en) * 2005-04-13 2016-11-22 Astrazeneca Ab A host cell comprising a vector for production of proteins requiring gamma-carboxylation
KR100937326B1 (ko) * 2007-12-26 2010-01-18 씨제이제일제당 (주) 옥시도리덕테이즈를 코딩하는 유전자가 불활성화된코리네박테리움 속 미생물 및 이를 이용한 5'-이노신산의제조방법
US9631002B2 (en) * 2010-12-21 2017-04-25 The University Of North Carolina At Chapel Hill Methods and compositions for producing active vitamin K-dependent proteins
KR101632642B1 (ko) 2015-01-29 2016-06-22 씨제이제일제당 주식회사 신규한 프로모터 및 그의 용도
JP6679803B2 (ja) 2016-08-31 2020-04-15 シージェイ チェイルジェダン コーポレーション 新規プロモーター及びその用途

Also Published As

Publication number Publication date
CA3222017A1 (en) 2023-01-05
WO2023277307A1 (ko) 2023-01-05
AU2022302574A1 (en) 2024-01-04
JP2024521482A (ja) 2024-05-31
CN118369433A (zh) 2024-07-19
MX2023015552A (es) 2024-01-24
TWI819552B (zh) 2023-10-21
TW202302838A (zh) 2023-01-16
US20240218381A1 (en) 2024-07-04
KR20230004002A (ko) 2023-01-06
KR102665227B1 (ko) 2024-05-10
EP4349991A1 (en) 2024-04-10

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