AR120069A2 - Nanomaterial de dióxido de titanio nanoparticulado modificado con grupos funcionales y con extractos cítricos adsorbidos en la superficie para la eliminación de amplio espectro de microorganismos - Google Patents
Nanomaterial de dióxido de titanio nanoparticulado modificado con grupos funcionales y con extractos cítricos adsorbidos en la superficie para la eliminación de amplio espectro de microorganismosInfo
- Publication number
- AR120069A2 AR120069A2 ARP200102114A ARP200102114A AR120069A2 AR 120069 A2 AR120069 A2 AR 120069A2 AR P200102114 A ARP200102114 A AR P200102114A AR P200102114 A ARP200102114 A AR P200102114A AR 120069 A2 AR120069 A2 AR 120069A2
- Authority
- AR
- Argentina
- Prior art keywords
- functional groups
- titanium dioxide
- adsorbed
- extracts
- support
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G23/00—Compounds of titanium
- C01G23/04—Oxides; Hydroxides
- C01G23/047—Titanium dioxide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6923—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being an inorganic particle, e.g. ceramic particles, silica particles, ferrite or synsorb
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y40/00—Manufacture or treatment of nanostructures
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D5/00—Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
- C09D5/14—Paints containing biocides, e.g. fungicides, insecticides or pesticides
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
- C09D7/40—Additives
- C09D7/60—Additives non-macromolecular
- C09D7/61—Additives non-macromolecular inorganic
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D7/00—Features of coating compositions, not provided for in group C09D5/00; Processes for incorporating ingredients in coating compositions
- C09D7/40—Additives
- C09D7/66—Additives characterised by particle size
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nanotechnology (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Botany (AREA)
- Crystallography & Structural Chemistry (AREA)
- Alternative & Traditional Medicine (AREA)
- General Life Sciences & Earth Sciences (AREA)
- Geology (AREA)
- Environmental & Geological Engineering (AREA)
- Ceramic Engineering (AREA)
- Physics & Mathematics (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- General Physics & Mathematics (AREA)
- Virology (AREA)
- Composite Materials (AREA)
Abstract
La presente se refiere al conjugado de un nanomaterial de dióxido de titanio y extractos herbales y/o frutales nanoparticulados (1 - 100 nm) sintetizado mediante el proceso de impregnación utilizado como soporte dióxido de titanio al que se le adsorben grupos funcionales orgánicos, radicales inorgánicos y extractos de plantas que le confieren la propiedad de ser un agente antimicrobiológico con un alto poder desinfectante y antiséptico, eliminando bacterias, hongos, micobacterias, esporas, micobacterias, protozoarios y virus. Ésta es una suspensión líquida de un nanomaterial sólido. Este material se prepara usando el proceso de impregnación para dispersar los grupos funcionales y las partículas de extractos; controlando la temperatura con el fin de estabilizar las interacciones dentro de la red del soporte. La actividad virucida, bactericida, fungicida, micobactericida, micoplasmicida, antiprotozoarios y esporicida del biomaterial nanoparticulado depende del, tamaño de las partículas de óxido de soporte, la funcionalización y la dispersión de extractos adsorbidos en la superficie. Los grupos funcionales pueden incluir hidroxilo, carboxilo, amina sulfato, fosfato y los soportes pueden ser dióxido de titanio, sílice, zirconia, óxido de zinc, alúmina y otros óxidos metálicos sin quedar restringido a estos soportes funcionales, extractos o soportes. Reivindicación 1: Un nanomaterial compuesto que se compone de: a) soporte de óxido metálico nanoparticulado, b) grupos funcionales adsorbidos químicamente en su superficie, c) extractos herbales y frutales adsorbidos físicamente en su superficie y poros.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2013007201A MX339086B (es) | 2013-06-20 | 2013-06-20 | Nanomaterial de dioxido de titanio nanoparticulado modificado con grupos funcionales y con extractos citricos adsorbidos en la superficie para la eliminacion de amplio espectro de microorganismos. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR120069A2 true AR120069A2 (es) | 2022-02-02 |
Family
ID=52104937
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140102324A AR096661A1 (es) | 2013-06-20 | 2014-06-19 | Nanomaterial de dióxido de titanio nanoparticulado modificado con grupos funcionales y con extractos cítricos adsorbidos en la superficie para la eliminación de amplio espectro de microorganismos |
| ARP200102114A AR120069A2 (es) | 2013-06-20 | 2020-07-28 | Nanomaterial de dióxido de titanio nanoparticulado modificado con grupos funcionales y con extractos cítricos adsorbidos en la superficie para la eliminación de amplio espectro de microorganismos |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140102324A AR096661A1 (es) | 2013-06-20 | 2014-06-19 | Nanomaterial de dióxido de titanio nanoparticulado modificado con grupos funcionales y con extractos cítricos adsorbidos en la superficie para la eliminación de amplio espectro de microorganismos |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US10342840B2 (es) |
| EP (1) | EP3012225A4 (es) |
| JP (1) | JP6625051B2 (es) |
| KR (1) | KR20160034299A (es) |
| CN (1) | CN105517956B (es) |
| AP (1) | AP2016009043A0 (es) |
| AR (2) | AR096661A1 (es) |
| AU (1) | AU2014281904A1 (es) |
| BR (1) | BR112015031884A2 (es) |
| CA (1) | CA2916216A1 (es) |
| CL (1) | CL2015003674A1 (es) |
| CR (1) | CR20160028A (es) |
| CU (1) | CU20150182A7 (es) |
| EA (1) | EA030364B1 (es) |
| HK (1) | HK1217099A1 (es) |
| IL (1) | IL243239B (es) |
| MA (1) | MA38707A1 (es) |
| MX (1) | MX339086B (es) |
| MY (1) | MY184044A (es) |
| PH (1) | PH12015502838A1 (es) |
| SA (1) | SA515370298B1 (es) |
| SG (1) | SG11201510528YA (es) |
| UY (1) | UY35623A (es) |
| WO (1) | WO2014204290A1 (es) |
| ZA (1) | ZA201509284B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201615196D0 (en) | 2016-09-07 | 2016-10-19 | Univ Limerick | Method for stabilising and isolating nanoparticles |
| US20210363465A1 (en) | 2017-07-20 | 2021-11-25 | Nanotess Inc. | Surface, material and personal cleaning formulation comprising nanostructured particles |
| PE20200753A1 (es) * | 2017-07-20 | 2020-07-27 | Gomez-Lopez Wenceslao | Biocatalizadores nanoestructurados y biocompatibles para su uso en el tratamiento del cancer |
| MX2019003969A (es) * | 2019-04-04 | 2022-06-23 | Inmolecule International Ltd | Diversos usos del compuesto nanoparticulado de dioxido de titanio funcionalizado. |
| CN110575412A (zh) * | 2019-09-30 | 2019-12-17 | 广东丸美生物技术股份有限公司 | 一种添加药用孔菌层提取物的毛孔专用美容液及其制备方法 |
| CN112426881B (zh) * | 2020-11-30 | 2022-03-25 | 桂林理工大学 | 一种仿生纳米除味剂、其制备方法及应用 |
| WO2022129983A1 (es) | 2020-12-14 | 2022-06-23 | LÓPEZ MACÍAS, Javier Eduardo | Nanosistemas basados en nanocompositos y extractos naturales |
| RU2763757C1 (ru) * | 2021-01-27 | 2022-01-10 | Общество с ограниченной ответственностью "ИННОКОЛЛОИД" | Способ блокирования бактериального и вирусного фона |
| US11746253B2 (en) * | 2021-03-08 | 2023-09-05 | Hoi Ming Michael HO | Sprayable conductive agent capable of forming conductive portion and manufacturing method and use thereof |
| CN114214198A (zh) * | 2021-12-22 | 2022-03-22 | 中溶科技股份有限公司 | 一种菌种保藏保护剂及其制备方法和应用 |
| CN115124862B (zh) * | 2022-07-12 | 2023-11-10 | 攀钢集团重庆钒钛科技有限公司 | 一种改性钛白粉及其制备方法 |
| CN115997812A (zh) * | 2023-01-06 | 2023-04-25 | 中国热带农业科学院南亚热带作物研究所 | 一种高效抗菌纳米保鲜材料及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI91713C (fi) | 1992-04-23 | 1994-08-10 | Axidental Oy | Uusia bioaktiivisia pinnotteita ja niiden valmistus ja käyttö |
| EP0727427A4 (en) | 1993-11-05 | 1997-10-15 | Meiji Milk Prod Co Ltd | ANTIBACTERIAL, ANTIFUNGAL AND ANTIVIRAL AGENT |
| US6117814A (en) | 1998-02-10 | 2000-09-12 | Exxon Research And Engineering Co. | Titania catalysts their preparation and use in fischer-tropsch synthesis |
| FR2835246B1 (fr) | 2002-01-29 | 2004-03-19 | Centre Nat Rech Scient | Polymere a base d'oxyde de titane |
| CN1634604A (zh) * | 2004-11-18 | 2005-07-06 | 黄琴根 | 复合纳米空气净化材料 |
| FR2881133B1 (fr) | 2005-01-27 | 2007-03-02 | Commissariat Energie Atomique | Procede de preparation de solutions sol-gel stable precurseurs de ceramiques oxydes a base de plomb, de titane, de zirconium et de lanthanide(s) et procede de preparation de ladite ceramique |
| EA013219B1 (ru) | 2006-01-19 | 2010-04-30 | Мэри Кэй, Инк. | Композиция местного применения по уходу за кожей, продукт на ее основе и способ лечения |
| WO2007093627A2 (de) * | 2006-02-16 | 2007-08-23 | Sachtleben Chemie Gmbh | Biozide zusammensetzung |
| JP5436207B2 (ja) | 2006-06-06 | 2014-03-05 | ウニベルシダッド アウトノマ メトロポリターナ | 中枢神経系へ薬物を制御下に放出するためのゾルゲルナノ構造チタニア貯蔵器および合成方法 |
| AU2007329579A1 (en) | 2006-12-01 | 2008-06-12 | Anterios, Inc. | Amphiphilic entity nanoparticles |
| US8178106B2 (en) | 2009-03-30 | 2012-05-15 | Mary Kay Inc. | Topical skin care formulations |
| JP2012532141A (ja) | 2009-06-30 | 2012-12-13 | ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク | 植物性成分を含有する抗微生物／防腐組成物 |
| WO2011026039A1 (en) | 2009-08-28 | 2011-03-03 | Mary Kay Inc. | Skin care formulations |
| US20120237455A1 (en) | 2009-12-04 | 2012-09-20 | Colgate-Palmolive Company | Oral compositions containing extracts of zizyphus joazeiro and related methods |
| MY160412A (en) | 2009-12-04 | 2017-03-15 | Colgate Palmolive Co | Oral compositions containing extracts of zingiber officinale and related methods |
| KR101907225B1 (ko) | 2010-10-01 | 2018-10-11 | 마리 케이 인코포레이티드 | 피부 보습제 및 노화 억제 제형 |
| WO2012058675A2 (en) | 2010-10-29 | 2012-05-03 | Mary Kay Inc. | Zinc oxide complexes |
| CN102077865B (zh) * | 2010-11-19 | 2013-12-04 | 华南农业大学 | 一种二氧化钛纳米颗粒及荔枝纳米保鲜剂 |
| CN102772715A (zh) * | 2012-07-05 | 2012-11-14 | 成钢 | 释放微量元素负离子防螨防电磁波纳米富银硒锗蛇油膏 |
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2013
- 2013-06-20 MX MX2013007201A patent/MX339086B/es active IP Right Grant
-
2014
- 2014-06-19 CN CN201480041557.8A patent/CN105517956B/zh not_active Expired - Fee Related
- 2014-06-19 JP JP2016521239A patent/JP6625051B2/ja active Active
- 2014-06-19 SG SG11201510528YA patent/SG11201510528YA/en unknown
- 2014-06-19 AR ARP140102324A patent/AR096661A1/es unknown
- 2014-06-19 EP EP14814634.3A patent/EP3012225A4/en active Pending
- 2014-06-19 US US14/899,628 patent/US10342840B2/en active Active
- 2014-06-19 MA MA38707A patent/MA38707A1/fr unknown
- 2014-06-19 EA EA201690030A patent/EA030364B1/ru active IP Right Revival
- 2014-06-19 MY MYPI2015003015A patent/MY184044A/en unknown
- 2014-06-19 AP AP2016009043A patent/AP2016009043A0/en unknown
- 2014-06-19 WO PCT/MX2014/000094 patent/WO2014204290A1/es active Application Filing
- 2014-06-19 CA CA2916216A patent/CA2916216A1/en not_active Abandoned
- 2014-06-19 KR KR1020167001526A patent/KR20160034299A/ko not_active Application Discontinuation
- 2014-06-19 BR BR112015031884A patent/BR112015031884A2/pt not_active IP Right Cessation
- 2014-06-19 AU AU2014281904A patent/AU2014281904A1/en not_active Abandoned
- 2014-06-23 UY UY35623A patent/UY35623A/es active IP Right Grant
-
2015
- 2015-12-18 CL CL2015003674A patent/CL2015003674A1/es unknown
- 2015-12-20 IL IL243239A patent/IL243239B/en active IP Right Grant
- 2015-12-20 SA SA515370298A patent/SA515370298B1/ar unknown
- 2015-12-21 CU CUP2015000182A patent/CU20150182A7/es unknown
- 2015-12-21 ZA ZA2015/09284A patent/ZA201509284B/en unknown
- 2015-12-21 PH PH12015502838A patent/PH12015502838A1/en unknown
-
2016
- 2016-01-15 CR CR20160028A patent/CR20160028A/es unknown
- 2016-05-04 HK HK16105054.4A patent/HK1217099A1/zh unknown
-
2020
- 2020-07-28 AR ARP200102114A patent/AR120069A2/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EA201690030A1 (ru) | 2016-10-31 |
| MA38707A1 (fr) | 2017-09-29 |
| CA2916216A1 (en) | 2014-12-24 |
| CL2015003674A1 (es) | 2016-08-19 |
| CR20160028A (es) | 2016-03-30 |
| MY184044A (en) | 2021-03-17 |
| PH12015502838A1 (en) | 2016-03-21 |
| EP3012225A4 (en) | 2017-02-22 |
| IL243239B (en) | 2020-07-30 |
| HK1217099A1 (zh) | 2016-12-23 |
| IL243239A0 (en) | 2016-02-29 |
| WO2014204290A1 (es) | 2014-12-24 |
| JP6625051B2 (ja) | 2019-12-25 |
| JP2016530222A (ja) | 2016-09-29 |
| AP2016009043A0 (en) | 2016-02-29 |
| AR096661A1 (es) | 2016-01-27 |
| KR20160034299A (ko) | 2016-03-29 |
| CN105517956A (zh) | 2016-04-20 |
| AU2014281904A1 (en) | 2016-02-18 |
| SA515370298B1 (ar) | 2017-06-07 |
| CU20150182A7 (es) | 2016-10-28 |
| US10342840B2 (en) | 2019-07-09 |
| BR112015031884A2 (pt) | 2017-07-25 |
| CN105517956B (zh) | 2017-09-29 |
| US20160143981A1 (en) | 2016-05-26 |
| MX339086B (es) | 2016-05-09 |
| EP3012225A1 (en) | 2016-04-27 |
| MX2013007201A (es) | 2014-12-22 |
| ZA201509284B (en) | 2017-09-27 |
| SG11201510528YA (en) | 2016-01-28 |
| UY35623A (es) | 2015-01-30 |
| EA030364B1 (ru) | 2018-07-31 |
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