AR114049A1 - Oxadiazoles fungicidas - Google Patents

Oxadiazoles fungicidas

Info

Publication number
AR114049A1
AR114049A1 ARP180103839A ARP180103839A AR114049A1 AR 114049 A1 AR114049 A1 AR 114049A1 AR P180103839 A ARP180103839 A AR P180103839A AR P180103839 A ARP180103839 A AR P180103839A AR 114049 A1 AR114049 A1 AR 114049A1
Authority
AR
Argentina
Prior art keywords
alkyl
aryl
carbocyclyl
heteroaryl
alkoxy
Prior art date
Application number
ARP180103839A
Other languages
English (en)
Inventor
Emmanuelle Hilt
Anne Rebstock
- Grtz Andreas Sophie
Mathieu Gourgues
Harald Jakobi
Stphane Brunet
Original Assignee
Bayer Cropscience Ag
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Cropscience Ag, Bayer Ag filed Critical Bayer Cropscience Ag
Publication of AR114049A1 publication Critical patent/AR114049A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/82Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

La presente se refiere a heterociclilaminofeniloxadiazol y derivados de este que se pueden usar y como fungicidas. Reivindicación 1: Un compuesto de la fórmula (1) o una sal de este, donde: X¹ representa N o CR¹; X² representa N o CR²; X³ representa N o CR³; X⁴ representa N o CR⁴; donde R¹, R², R³ y R⁴, cuando están presentes, representan independientemente hidrógeno, halógeno o C₁₋₃-alquilo; R⁵ representa CF₃ o CF₂Cl; Z representa arilo, heteroarilo C₃₋₁₀-carbociclilo o heterociclilo de 3 a 10 miembros, donde dicho arilo, heteroarilo, C₃₋₁₀-carbociclilo o heterociclilo de 3 a 10 miembros, está opcionalmente sustituido por uno o más sustituyentes que pueden ser iguales o diferentes, que se seleccionan del grupo que consiste en SF₅, halógeno, ciano, hidroxi, amino, nitro, C₁₋₆-alquilo, C₁₋₆-cianoalquilo, C₁₋₆haloalquilo, C₂₋₆-alquenilo, C₂₋₆-haloalquenilo, C₂₋₆-alquinilo, C₂₋₆-haloalquinilo, C₁₋₆-alcoxi, C₁₋₆-haloalcoxi, C₁₋₆-alcoxi-C₁₋₆-alquilo, C₁₋₆-alquiltio, C₁₋₆-haloalquiltio, C₁₋₆-alquil-C(=O)-NH-, C₃₋₁₀-carbociclilo, C₃₋₁₀-halocarbociclilo, hidroxi-C₁₋₆-alquilo, C₁₋₆-alquilamino, diC₁₋₆-alquilamino, C₁₋₆-alquilcarbonilo, C₁₋₆-alcoxicarbonilo, aminocarbonilo, arilo (por ejemplo fenilo), aril-C₁₋₆-alquilo y heteroarilo, donde dicho arilo o heteroarilo está opcionalmente sustituido por uno o más sustituyentes, que pueden ser iguales o diferentes, que se seleccionan del grupo que consiste en halógeno, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₁₋₆-alcoxi y C₁₋₆-haloalcoxi; e Y representa hidrógeno, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₂₋₆-alquenilo, C₂₋₆-haloalquenilo, C₂₋₆-alquinilo, C₂₋₆-haloalquinilo, -C(=O)-C₁₋₆-alquilo, -C(=S)-C₁₋₆-alquilo, -C(=O)-O-C₁₋₆-alquilo, C₁₋₆-alcoxi, C₁₋₆-haloalcoxi, C₁₋₆-alquilsulfonilo, C₁₋₆-haloalquilsulfonilo, C₃₋₁₀-carbociclilo, heterociclilo de 3 a 10 miembros, arilo (fenilo) o heteroarilo donde dicho Y está opcionalmente sustituido por halógeno, ciano, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₁₋₆-alcoxi o C₁₋₆-haloalcoxi, con la condición de que Z no sea un piperidinilo insustituido ni un piperidinilo sustituido por un C₁₋₆-alcoxicarbonilo cuando X¹, X² y X³ son CH, X⁴ es N, Y es H y R⁵ es CF₃, o cuando X¹ y X² son CH, X³ y X⁴ son N, Y es H y R⁵ es CF₃; siempre que Z sea diferente de C₃₋₁₀-carbociclilo cuando Y es C(=O)-C₁₋₆-alquilo, -C(=O)-O-C₁₋₆-alquilo, -C(=S)-C₁₋₆-alquilo o C₁₋₆-alquilsulfonilo y R⁵ es CF₃; con la condición de que Z no sea fenilo o heteroarilo de 6 miembros cuando X¹ y X² son CH, X³ es CR³ con R³ es hidrógeno o cloro, X⁴ es N, Y es hidrógeno o C₁₋₆-alquilo y R⁵ es CF₃, y siempre que los compuestos de la fórmula (1) no sean: acetamida, 2,2,2-trifluoro-N-[(1R,2S)-2-fenilciclohexil]-N-(5-[5-(trifluorometil)-1,2,4-oxadiazol-3-il]-2-piridinil] (2170456-65-0); 2-piridinamina, N-[(1R,2S)-2-fenilciclohexil]-5-[5-(trifluorometil)-1,2,4-oxadiazol-3-il]- (2170451-91-7).
ARP180103839A 2017-12-22 2018-12-21 Oxadiazoles fungicidas AR114049A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP17210460 2017-12-22

Publications (1)

Publication Number Publication Date
AR114049A1 true AR114049A1 (es) 2020-07-15

Family

ID=60811938

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP180103839A AR114049A1 (es) 2017-12-22 2018-12-21 Oxadiazoles fungicidas

Country Status (13)

Country Link
US (1) US11266147B2 (es)
EP (1) EP3728244A1 (es)
CN (1) CN111683944A (es)
AR (1) AR114049A1 (es)
AU (1) AU2018386567A1 (es)
BR (1) BR112020012530B1 (es)
CA (1) CA3086790A1 (es)
CR (1) CR20200274A (es)
MX (1) MX2020006595A (es)
RU (1) RU2020124113A (es)
TW (1) TW201927775A (es)
UY (1) UY38032A (es)
WO (1) WO2019122323A1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018165520A1 (en) 2017-03-10 2018-09-13 Vps-3, Inc. Metalloenzyme inhibitor compounds
KR20210098949A (ko) * 2018-10-01 2021-08-11 피아이 인더스트리스 엘티디. 새로운 옥사디아졸
WO2020254494A1 (en) 2019-06-21 2020-12-24 Bayer Aktiengesellschaft Fungicidal oxadiazoles
CN111592533B (zh) * 2020-06-16 2021-08-24 浙江工业大学 1,2,4-噁二唑联吡啶取代苯甲酰胺类化合物及其制备方法和应用
UY39276A (es) 2020-06-19 2022-01-31 Bayer Ag Uso de compuestos de 1,3,4–oxadiazol–2–ilpirimidina para controlar microorganismos fitopatógenos, métodos de uso y composiciones.
UY39275A (es) 2020-06-19 2022-01-31 Bayer Ag 1,3,4-oxadiazol pirimidinas como fungicidas, procesos e intermediarios para su preparación, métodos de uso y usos de los mismos
CN111943944B (zh) * 2020-09-08 2021-11-23 浙江工业大学 含乙硫基吡啶联1,2,4-噁二唑取代苯甲酰胺类化合物及其制备方法和应用
WO2022129188A1 (en) 2020-12-18 2022-06-23 Bayer Aktiengesellschaft 1,2,4-oxadiazol-3-yl pyrimidines as fungicides
WO2022129190A1 (en) 2020-12-18 2022-06-23 Bayer Aktiengesellschaft (hetero)aryl substituted 1,2,4-oxadiazoles as fungicides
RU2766333C1 (ru) * 2021-03-24 2022-03-15 Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) Новые n4-модифицированные 5-метил-2'-дезоксицитидины, проявляющие антимикозную активность
BR112023019788A2 (pt) 2021-03-30 2023-11-07 Bayer Ag 3-(hetero)aril-5-clorodifluorometil-1,2,4-oxadiazol como fungicida
WO2022207494A1 (en) 2021-03-30 2022-10-06 Bayer Aktiengesellschaft 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide
WO2024068520A1 (en) 2022-09-28 2024-04-04 Bayer Aktiengesellschaft 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide
WO2024068517A1 (en) 2022-09-28 2024-04-04 Bayer Aktiengesellschaft 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide
WO2024068519A1 (en) 2022-09-28 2024-04-04 Bayer Aktiengesellschaft 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide
WO2024068518A1 (en) 2022-09-28 2024-04-04 Bayer Aktiengesellschaft 3-heteroaryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013066831A1 (en) * 2011-10-31 2013-05-10 Glaxosmithkline Llc Compounds and methods
JP5966014B2 (ja) 2011-11-28 2016-08-10 ノバルティス アーゲー 新規トリフルオロメチル−オキサジアゾール誘導体および疾患の処置におけるその使用
EP3373732A1 (en) * 2015-11-13 2018-09-19 Basf Se Substituted oxadiazoles for combating phytopathogenic fungi
WO2017110862A1 (ja) 2015-12-25 2017-06-29 住友化学株式会社 オキサジアゾール化合物及びその用途
EP3475275B1 (en) * 2016-06-23 2024-04-10 Merck Sharp & Dohme LLC 3-aryl and heteroaryl substituted 5-trifluoromethyl oxadiazoles as histone deacetylase 6 (hdac6) inhibitors
TW202334101A (zh) 2017-04-06 2023-09-01 美商富曼西公司 殺真菌之噁二唑

Also Published As

Publication number Publication date
AU2018386567A1 (en) 2020-07-02
US20210007359A1 (en) 2021-01-14
MX2020006595A (es) 2020-09-10
BR112020012530A2 (pt) 2020-11-24
US11266147B2 (en) 2022-03-08
CN111683944A (zh) 2020-09-18
BR112020012530B1 (pt) 2024-04-30
UY38032A (es) 2019-07-31
TW201927775A (zh) 2019-07-16
EP3728244A1 (en) 2020-10-28
CR20200274A (es) 2020-08-13
RU2020124113A (ru) 2022-01-24
WO2019122323A1 (en) 2019-06-27
CA3086790A1 (en) 2019-06-27

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