AR114049A1 - Oxadiazoles fungicidas - Google Patents
Oxadiazoles fungicidasInfo
- Publication number
- AR114049A1 AR114049A1 ARP180103839A ARP180103839A AR114049A1 AR 114049 A1 AR114049 A1 AR 114049A1 AR P180103839 A ARP180103839 A AR P180103839A AR P180103839 A ARP180103839 A AR P180103839A AR 114049 A1 AR114049 A1 AR 114049A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- aryl
- carbocyclyl
- heteroaryl
- alkoxy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
La presente se refiere a heterociclilaminofeniloxadiazol y derivados de este que se pueden usar y como fungicidas. Reivindicación 1: Un compuesto de la fórmula (1) o una sal de este, donde: X¹ representa N o CR¹; X² representa N o CR²; X³ representa N o CR³; X⁴ representa N o CR⁴; donde R¹, R², R³ y R⁴, cuando están presentes, representan independientemente hidrógeno, halógeno o C₁₋₃-alquilo; R⁵ representa CF₃ o CF₂Cl; Z representa arilo, heteroarilo C₃₋₁₀-carbociclilo o heterociclilo de 3 a 10 miembros, donde dicho arilo, heteroarilo, C₃₋₁₀-carbociclilo o heterociclilo de 3 a 10 miembros, está opcionalmente sustituido por uno o más sustituyentes que pueden ser iguales o diferentes, que se seleccionan del grupo que consiste en SF₅, halógeno, ciano, hidroxi, amino, nitro, C₁₋₆-alquilo, C₁₋₆-cianoalquilo, C₁₋₆haloalquilo, C₂₋₆-alquenilo, C₂₋₆-haloalquenilo, C₂₋₆-alquinilo, C₂₋₆-haloalquinilo, C₁₋₆-alcoxi, C₁₋₆-haloalcoxi, C₁₋₆-alcoxi-C₁₋₆-alquilo, C₁₋₆-alquiltio, C₁₋₆-haloalquiltio, C₁₋₆-alquil-C(=O)-NH-, C₃₋₁₀-carbociclilo, C₃₋₁₀-halocarbociclilo, hidroxi-C₁₋₆-alquilo, C₁₋₆-alquilamino, diC₁₋₆-alquilamino, C₁₋₆-alquilcarbonilo, C₁₋₆-alcoxicarbonilo, aminocarbonilo, arilo (por ejemplo fenilo), aril-C₁₋₆-alquilo y heteroarilo, donde dicho arilo o heteroarilo está opcionalmente sustituido por uno o más sustituyentes, que pueden ser iguales o diferentes, que se seleccionan del grupo que consiste en halógeno, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₁₋₆-alcoxi y C₁₋₆-haloalcoxi; e Y representa hidrógeno, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₂₋₆-alquenilo, C₂₋₆-haloalquenilo, C₂₋₆-alquinilo, C₂₋₆-haloalquinilo, -C(=O)-C₁₋₆-alquilo, -C(=S)-C₁₋₆-alquilo, -C(=O)-O-C₁₋₆-alquilo, C₁₋₆-alcoxi, C₁₋₆-haloalcoxi, C₁₋₆-alquilsulfonilo, C₁₋₆-haloalquilsulfonilo, C₃₋₁₀-carbociclilo, heterociclilo de 3 a 10 miembros, arilo (fenilo) o heteroarilo donde dicho Y está opcionalmente sustituido por halógeno, ciano, C₁₋₆-alquilo, C₁₋₆-haloalquilo, C₁₋₆-alcoxi o C₁₋₆-haloalcoxi, con la condición de que Z no sea un piperidinilo insustituido ni un piperidinilo sustituido por un C₁₋₆-alcoxicarbonilo cuando X¹, X² y X³ son CH, X⁴ es N, Y es H y R⁵ es CF₃, o cuando X¹ y X² son CH, X³ y X⁴ son N, Y es H y R⁵ es CF₃; siempre que Z sea diferente de C₃₋₁₀-carbociclilo cuando Y es C(=O)-C₁₋₆-alquilo, -C(=O)-O-C₁₋₆-alquilo, -C(=S)-C₁₋₆-alquilo o C₁₋₆-alquilsulfonilo y R⁵ es CF₃; con la condición de que Z no sea fenilo o heteroarilo de 6 miembros cuando X¹ y X² son CH, X³ es CR³ con R³ es hidrógeno o cloro, X⁴ es N, Y es hidrógeno o C₁₋₆-alquilo y R⁵ es CF₃, y siempre que los compuestos de la fórmula (1) no sean: acetamida, 2,2,2-trifluoro-N-[(1R,2S)-2-fenilciclohexil]-N-(5-[5-(trifluorometil)-1,2,4-oxadiazol-3-il]-2-piridinil] (2170456-65-0); 2-piridinamina, N-[(1R,2S)-2-fenilciclohexil]-5-[5-(trifluorometil)-1,2,4-oxadiazol-3-il]- (2170451-91-7).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17210460 | 2017-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR114049A1 true AR114049A1 (es) | 2020-07-15 |
Family
ID=60811938
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP180103839A AR114049A1 (es) | 2017-12-22 | 2018-12-21 | Oxadiazoles fungicidas |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US11266147B2 (es) |
| EP (1) | EP3728244A1 (es) |
| CN (1) | CN111683944A (es) |
| AR (1) | AR114049A1 (es) |
| AU (1) | AU2018386567A1 (es) |
| BR (1) | BR112020012530B1 (es) |
| CA (1) | CA3086790A1 (es) |
| CR (1) | CR20200274A (es) |
| MX (1) | MX2020006595A (es) |
| RU (1) | RU2020124113A (es) |
| TW (1) | TW201927775A (es) |
| UY (1) | UY38032A (es) |
| WO (1) | WO2019122323A1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018165520A1 (en) | 2017-03-10 | 2018-09-13 | Vps-3, Inc. | Metalloenzyme inhibitor compounds |
| KR20210098949A (ko) * | 2018-10-01 | 2021-08-11 | 피아이 인더스트리스 엘티디. | 새로운 옥사디아졸 |
| WO2020254494A1 (en) | 2019-06-21 | 2020-12-24 | Bayer Aktiengesellschaft | Fungicidal oxadiazoles |
| CN111592533B (zh) * | 2020-06-16 | 2021-08-24 | 浙江工业大学 | 1,2,4-噁二唑联吡啶取代苯甲酰胺类化合物及其制备方法和应用 |
| UY39276A (es) | 2020-06-19 | 2022-01-31 | Bayer Ag | Uso de compuestos de 1,3,4–oxadiazol–2–ilpirimidina para controlar microorganismos fitopatógenos, métodos de uso y composiciones. |
| UY39275A (es) | 2020-06-19 | 2022-01-31 | Bayer Ag | 1,3,4-oxadiazol pirimidinas como fungicidas, procesos e intermediarios para su preparación, métodos de uso y usos de los mismos |
| CN111943944B (zh) * | 2020-09-08 | 2021-11-23 | 浙江工业大学 | 含乙硫基吡啶联1,2,4-噁二唑取代苯甲酰胺类化合物及其制备方法和应用 |
| WO2022129188A1 (en) | 2020-12-18 | 2022-06-23 | Bayer Aktiengesellschaft | 1,2,4-oxadiazol-3-yl pyrimidines as fungicides |
| WO2022129190A1 (en) | 2020-12-18 | 2022-06-23 | Bayer Aktiengesellschaft | (hetero)aryl substituted 1,2,4-oxadiazoles as fungicides |
| RU2766333C1 (ru) * | 2021-03-24 | 2022-03-15 | Федеральное Государственное Бюджетное Учреждение Науки Институт Молекулярной Биологии Им. В.А. Энгельгардта Российской Академии Наук (Имб Ран) | Новые n4-модифицированные 5-метил-2'-дезоксицитидины, проявляющие антимикозную активность |
| BR112023019788A2 (pt) | 2021-03-30 | 2023-11-07 | Bayer Ag | 3-(hetero)aril-5-clorodifluorometil-1,2,4-oxadiazol como fungicida |
| WO2022207494A1 (en) | 2021-03-30 | 2022-10-06 | Bayer Aktiengesellschaft | 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide |
| WO2024068520A1 (en) | 2022-09-28 | 2024-04-04 | Bayer Aktiengesellschaft | 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide |
| WO2024068517A1 (en) | 2022-09-28 | 2024-04-04 | Bayer Aktiengesellschaft | 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide |
| WO2024068519A1 (en) | 2022-09-28 | 2024-04-04 | Bayer Aktiengesellschaft | 3-(hetero)aryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide |
| WO2024068518A1 (en) | 2022-09-28 | 2024-04-04 | Bayer Aktiengesellschaft | 3-heteroaryl-5-chlorodifluoromethyl-1,2,4-oxadiazole as fungicide |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013066831A1 (en) * | 2011-10-31 | 2013-05-10 | Glaxosmithkline Llc | Compounds and methods |
| JP5966014B2 (ja) | 2011-11-28 | 2016-08-10 | ノバルティス アーゲー | 新規トリフルオロメチル−オキサジアゾール誘導体および疾患の処置におけるその使用 |
| EP3373732A1 (en) * | 2015-11-13 | 2018-09-19 | Basf Se | Substituted oxadiazoles for combating phytopathogenic fungi |
| WO2017110862A1 (ja) | 2015-12-25 | 2017-06-29 | 住友化学株式会社 | オキサジアゾール化合物及びその用途 |
| EP3475275B1 (en) * | 2016-06-23 | 2024-04-10 | Merck Sharp & Dohme LLC | 3-aryl and heteroaryl substituted 5-trifluoromethyl oxadiazoles as histone deacetylase 6 (hdac6) inhibitors |
| TW202334101A (zh) | 2017-04-06 | 2023-09-01 | 美商富曼西公司 | 殺真菌之噁二唑 |
-
2018
- 2018-12-21 WO PCT/EP2018/086557 patent/WO2019122323A1/en unknown
- 2018-12-21 UY UY0001038032A patent/UY38032A/es not_active Application Discontinuation
- 2018-12-21 MX MX2020006595A patent/MX2020006595A/es unknown
- 2018-12-21 CA CA3086790A patent/CA3086790A1/en active Pending
- 2018-12-21 BR BR112020012530-0A patent/BR112020012530B1/pt active IP Right Grant
- 2018-12-21 TW TW107146453A patent/TW201927775A/zh unknown
- 2018-12-21 CR CR20200274A patent/CR20200274A/es unknown
- 2018-12-21 CN CN201880089467.4A patent/CN111683944A/zh active Pending
- 2018-12-21 AR ARP180103839A patent/AR114049A1/es unknown
- 2018-12-21 RU RU2020124113A patent/RU2020124113A/ru unknown
- 2018-12-21 EP EP18833881.8A patent/EP3728244A1/en not_active Withdrawn
- 2018-12-21 US US16/955,390 patent/US11266147B2/en active Active
- 2018-12-21 AU AU2018386567A patent/AU2018386567A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2018386567A1 (en) | 2020-07-02 |
| US20210007359A1 (en) | 2021-01-14 |
| MX2020006595A (es) | 2020-09-10 |
| BR112020012530A2 (pt) | 2020-11-24 |
| US11266147B2 (en) | 2022-03-08 |
| CN111683944A (zh) | 2020-09-18 |
| BR112020012530B1 (pt) | 2024-04-30 |
| UY38032A (es) | 2019-07-31 |
| TW201927775A (zh) | 2019-07-16 |
| EP3728244A1 (en) | 2020-10-28 |
| CR20200274A (es) | 2020-08-13 |
| RU2020124113A (ru) | 2022-01-24 |
| WO2019122323A1 (en) | 2019-06-27 |
| CA3086790A1 (en) | 2019-06-27 |
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