AR106423A1 - Un proceso para la preparación de triptaminas y sus derivados - Google Patents
Un proceso para la preparación de triptaminas y sus derivadosInfo
- Publication number
- AR106423A1 AR106423A1 ARP160103209A ARP160103209A AR106423A1 AR 106423 A1 AR106423 A1 AR 106423A1 AR P160103209 A ARP160103209 A AR P160103209A AR P160103209 A ARP160103209 A AR P160103209A AR 106423 A1 AR106423 A1 AR 106423A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- aryl
- alkoxy
- substituted
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
Reivindicación 1: Un proceso para la preparación del compuesto de la fórmula (1) o una sal de este, en donde el anillo aromático opcionalmente puede sustituirse con uno o más sustituyentes seleccionados a partir de alquilo, alquilo sustituido con alcoxi o hidroxilo, cicloalquilo, arilo, arilo sustituido con hidroxilo, alquilo, alcoxi, halógeno, carboxi, alcoxicarbonilo, amido, N-alquilamido, sulfonilamido, ciano, haloalquilo, haloalcoxi, nitro, heteroarilo, heterociclilo, alquenilo, alquinilo, halógeno, hidroxilo, alcoxi, ariloxi, alcoxicarbonilo, ariloxicarbonilo, tiol, tioéter de alquilo, tioéter de arilo, tioéster de alquilo, tioéster de arilo, grupo aldehído, arilcarbonilo, alquilocarbonilo, carboxilo, carboxilo esterificado con alquilo o arilo, amida, amina, nitrilo, alquilsulfonilo, arilsulfonilo y amidosulfonilo, que comprenden la conversión del compuesto de la fórmula (2), en donde el anillo aromático opcionalmente puede sustituirse con uno o más sustituyentes como se definió anteriormente, en el compuesto de la fórmula (1) en presencia de un agente reductor.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP2015002105 | 2015-10-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR106423A1 true AR106423A1 (es) | 2018-01-10 |
Family
ID=57209421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP160103209A AR106423A1 (es) | 2015-10-23 | 2016-10-21 | Un proceso para la preparación de triptaminas y sus derivados |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN108271369A (es) |
| AR (1) | AR106423A1 (es) |
| WO (1) | WO2017067670A1 (es) |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5403851A (en) | 1994-04-05 | 1995-04-04 | Interneuron Pharmaceuticals, Inc. | Substituted tryptamines, phenalkylamines and related compounds |
| WO1997040024A1 (en) | 1996-04-23 | 1997-10-30 | Merck & Co., Inc. | Pyrazinone thrombin inhibitors |
| WO2001068648A1 (en) | 2000-03-15 | 2001-09-20 | Aventis Pharma Deutschland Gmbh | Substituted beta-carbolines with ikb-kinase inhibiting activity |
| MXPA03008726A (es) | 2001-03-29 | 2003-12-12 | Lilly Co Eli | N-(2-ariletil)benzilaminas como antagonistas del receptor 5-ht6. |
| GB0119243D0 (en) | 2001-08-07 | 2001-10-03 | Pharma Mar Sa | Antitumoral analogs of ET-743 |
| US7595311B2 (en) | 2002-05-24 | 2009-09-29 | Exelixis, Inc. | Azepinoindole derivatives as pharmaceutical agents |
| DE10252667A1 (de) | 2002-11-11 | 2004-05-27 | Grünenthal GmbH | Spirocyclische Cyclohexan-Derivate |
| CN1729174B (zh) * | 2002-12-20 | 2015-10-21 | 西巴特殊化学品控股有限公司 | 胺的合成以及用于合成胺的中间体 |
| JP2006522824A (ja) | 2003-04-09 | 2006-10-05 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | 炎症性疾患を処置するために有用なβ−カルボリン |
| UA88638C2 (ru) | 2004-04-09 | 2009-11-10 | Милленниум Фармасьютикалз, Инк. | Бета-карболины, полезные для лечения воспалительного заболевания |
| US7989458B2 (en) | 2006-07-14 | 2011-08-02 | Novartis Ag | Pyrimidine derivatives as alk-5 inhibitors |
| DE102006033109A1 (de) * | 2006-07-18 | 2008-01-31 | Grünenthal GmbH | Substituierte Heteroaryl-Derivate |
| CA2706651A1 (en) | 2007-12-04 | 2009-06-11 | Merck Sharp & Dohme Corp. | Tryptamine sulfonamides as 5-ht6 antagonists |
| EP2334643A1 (en) | 2008-10-14 | 2011-06-22 | Actelion Pharmaceuticals Ltd. | Phenethylamide derivatives and their heterocyclic analogues |
| EP2375899B1 (en) | 2009-01-12 | 2015-02-25 | Array Biopharma Inc. | Piperidine-containing compounds and use thereof in the treatment of diabetes |
| CN102177686A (zh) | 2009-06-12 | 2011-09-07 | 华为技术有限公司 | 一种传送视频报文的方法、路由器设备及系统 |
| TW201139370A (en) * | 2009-12-23 | 2011-11-16 | Lundbeck & Co As H | Processes for the manufacture of a pharmaceutically active agent |
| CN102659662A (zh) * | 2012-03-28 | 2012-09-12 | 华东师范大学 | 3-r-3-羟基-2-氧化吲哚类化合物的合成方法 |
-
2016
- 2016-10-19 CN CN201680061481.4A patent/CN108271369A/zh active Pending
- 2016-10-19 WO PCT/EP2016/025121 patent/WO2017067670A1/en active Application Filing
- 2016-10-21 AR ARP160103209A patent/AR106423A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2017067670A1 (en) | 2017-04-27 |
| CN108271369A (zh) | 2018-07-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure | ||
| FB | Suspension of granting procedure |