AR089882A1 - PIRIMIDINE FUNGICIDE COMPOUNDS - Google Patents
PIRIMIDINE FUNGICIDE COMPOUNDSInfo
- Publication number
- AR089882A1 AR089882A1 ARP130100326A AR089882A1 AR 089882 A1 AR089882 A1 AR 089882A1 AR P130100326 A ARP130100326 A AR P130100326A AR 089882 A1 AR089882 A1 AR 089882A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- alkoxy
- haloalkoxy
- haloalkyl
- alkynyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Compuestos I fungicidas de pirimidina, su uso y los métodos para combatir hongos fitopatogénicos. Asimismo, procesos para preparar compuestos de la fórmula (1) e intermediarios. Reivindicación 1: Compuestos de la fórmula (1) en donde: Rᵃ⁵ es metoxi o halometoxi; Rᵃ², Rᵃ⁶ son, independientemente entre sí, hidrógeno, halógeno, CN, NO₂, OH, SH, alquilo C₁₋₄, haloalquilo C₁₋₄, alcoxi C₁₋₄, haloalcoxi C₁₋₄, alquiltio C₁₋₄, haloalquiltio C₁₋₄, alquilsulfinilo C₁₋₄, haloalquilsulfinilo C₁₋₄, alquilsulfonilo C₁₋₄, haloalquilsulfonilo C₁₋₄, alcoxi C₁₋₄-alquilo C₁₋₄, alcoxi C₁₋₄-alcoxi C₁₋₄, alquenilo C₂₋₄, alquinilo C₂₋₄, haloalquenilo C₂₋₄, haloalquinilo C₂₋₄, cicloalquilo C₃₋₈, cicloalquiloxi C₃₋₈, cicloalquil C₃₋₈-alquilo C₁₋₄, NRARB, C(=O)R, C(=NOR)R o C(=NH)-O-R; RA, RB son, independientemente entre sí, hidrógeno, alquilo C₁₋₄, alquenilo C₂₋₄, alquinilo C₂₋₄, fenilo, bencilo, cicloalquilo C₃₋₈, cicloalquenilo C₃₋₈ o C(=O)-R; R es hidrógeno, OH, NH₂, alquilo C₁₋₄, haloalquilo C₁₋₄, alquenilo C₂₋₄, alquinilo C₂₋₄, alcoxi C₁₋₄, haloalcoxi C₁₋₄, alquilamino C₁₋₄ o di(alquil C₁₋₄)amino; R es hidrógeno, alquilo C₁₋₄, haloalquilo C₁₋₄, alquenilo C₂₋₄, alquinilo C₂₋₄ o alcoxi C₁₋₄-alquilo C₁₋₄, R es hidrógeno o alquilo C₁₋₄; R es hidrógeno, alquilo C₁₋₄, haloalquilo C₁₋₄, alcoxi C₁₋₄, haloalcoxi C₁₋₄, alcoxi C₁₋₄-alquilo C₁₋₄, haloalcoxi C₁₋₄-alquilo C₁₋₄, alquenilo C₂₋₄, haloalquenilo C₂₋₄, alquinilo C₂₋₄, haloalquinilo C₂₋₄, CN, CH₂CN, NRARB o CH₂-O-C(=O)R; R¹, R² son, independientemente entre sí, hidrógeno, halógeno, OH, CN, alquilo C₁₋₄, haloalquilo C₁₋₄, alcoxi C₁₋₄, haloalcoxi C₁₋₄, alcoxi C₁₋₄-alquilo C₁₋₄, haloalcoxi C₁₋₄-alquilo C₁₋₄, alquenilo C₂₋₄, haloalquenilo C₂₋₄, alquinilo C₂₋₄, haloalquinilo C₂₋₄, cicloalquilo C₃₋₈, cicloalquiloxi C₃₋₈, cicloalquil C₃₋₈-alquilo C₁₋₄, NRARB, C(=O)R, C(=NOR)R, C(=NH)-O-R o bencilo, en donde la porción fenilo de bencilo es no sustituida o tiene 1, 2, 3, 4 ó 5 sustituyentes seleccionados del grupo que consiste en CN, halógeno, alquilo C₁₋₄, haloalquilo C₁₋₄, alcoxi C₁₋₄, haloalcoxi C₁₋₄, (alcoxi C₁₋₄)carbonilo y di(alquil C₁₋₄)aminocarbonilo, o dos radicales R¹ y R² que se unen al mismo átomo de carbono forman, junto con dicho átomo de carbono, un carbociclo saturado o parcialmente insaturado de 3, 4, 5, 6 ó 7 miembros o un heterociclo saturado o parcialmente insaturado de 3, 4, 5, 6 ó 7 miembros, en donde los átomos miembros del anillo del heterociclo antes mencionado incluyen, además de átomos de carbono, 1, 2, 3 ó 4 heteroátomos seleccionados del grupo de N, O y S, y en donde el ciclo antes mencionado es no sustituido o tiene 1, 2, 3 ó 4 sustituyentes seleccionados de halógeno, CN, OH, SH, alquilo C₁₋₄, alcoxi C₁₋₄ o alquiltio C₁₋₄; y uno o dos grupos CH₂ de los ciclos antes mencionados se pueden reemplazar por uno o dos grupos C(=O) o C(=S), respectivamente; n indica la cantidad de sustituyentes Rᵇ en el anillo fenilo, y n es 0, 1, 2, 3 ó 4; Rᵇ es halógeno, CN, NO₂, alquilo C₁₋₄, haloalquilo C₁₋₄, alcoxi C₁₋₄, haloalcoxi C₁₋₄, alquenilo C₂₋₄, haloalquenilo C₂₋₄, alquinilo C₂₋₄, haloalquinilo C₂₋₄, NRARB, C(=NOR)R o C(=NH)-O-R, en donde es posible para n = 2, 3 ó 4 que Rᵇ sean idénticos o diferentes; Het es un heteroarilo de 5 ó 6 miembros, en donde los átomos miembros del anillo del heteroarilo incluyen, además de átomos de carbono, 1, 2, 3 ó 4 heteroátomos seleccionados del grupo de N, O y S y en donde el heteroarilo es no sustituido o tiene 1, 2, 3 ó 4 grupos Rᶜ idénticos o diferentes: Rᶜ es halógeno, CN, NO₂, alquilo C₁₋₆, haloalquilo C₁₋₆, alcoxi C₁₋₆, haloalcoxi C₁₋₆, alquiltio C₁₋₆, haloalquiltio C₁₋₆, alquilsulfinilo C₁₋₆, haloalquilsulfinilo C₁₋₆, alquilsulfonilo C₁₋₆, haloalquilsulfonilo C₁₋₆, alcoxi C₁₋₆-alquilo C₁₋₄, haloalcoxi C₁₋₆-alquilo C₁₋₄, alquenilo C₂₋₆, alquinilo C₂₋₆, NRARB, C(=O)R, C(=NOR)R, C(=NH)-O-R, cicloalquilo C₃₋₈, cicloalquil C₃₋₈-alquilo C₁₋₄, fenilo, fenil-alquilo C₁₋₄, fenoxi, fenoxi-alquilo C₁₋₄ o un heteroarilo de 5 ó 6 miembros, en donde los átomos miembros del anillo del heteroarilo incluyen, además de átomos de carbono, 1, 2, 3 ó 4 heteroátomos seleccionados del grupo de N, O y S, y en donde los radicales cíclicos antes mencionados son no sustituidos o tienen 1, 2, 3 ó 4 sustituyentes Rᵈ idénticos o diferentes: Rᵈ es halógeno, CN, alquilo C₁₋₄, haloalquilo C₁₋₄, alcoxi C₁₋₄ o haloalcoxi C₁₋₄; o dos radicales Rᶜ que se unen a los átomos miembros del anillo adyacente del grupo Het forman, junto con dichos átomos miembros del anillo, un carbociclo o heterociclo fusionado, saturado, parcialmente insaturado o aromático de 5, 6 ó 7 miembros, en donde los átomos miembros del anillo del heterociclo fusionado incluyen, además de átomos de carbono, 1, 2, 3 ó 4 heteroátomos seleccionados del grupo de N, O y S, y en donde el carbociclo o heterociclo fusionado es no sustituido o tiene 1, 2, 3 ó 4 grupos radicales Rᵉ idénticos o diferentes: Rᵉ es halógeno, CN, alquilo C₁₋₄, haloalquilo C₁₋₄, alcoxi C₁₋₄ o haloalcoxi C₁₋₄; y los N-óxidos y las sales de estos aceptables en la agricultura.Pyrimidine fungicidal compounds I, their use and methods to combat phytopathogenic fungi. Also, processes for preparing compounds of the formula (1) and intermediates. Claim 1: Compounds of the formula (1) wherein: Rᵃ⁵ is methoxy or halomethoxy; Rᵃ², Rᵃ⁶ are, independently of each other, hydrogen, halogen, CN, NO₂, OH, SH, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₁₋₄ alkoxy, C₁₋₄ haloalkoxy, C₁₋₄ alkylthio, C₁₋₄ haloalkylthio , C₁₋₄ alkylsulfinyl, C₁₋₄ haloalkylsulfinyl, C₁₋₄ alkylsulfonyl, C₁₋₄ haloalkylsulfonyl, C₁₋₄ alkoxyC₁₋₄ alkyl, C₁₋₄ alkoxyC₁₋₄ alkoxy, C₂₋₄ alkenyl, C₂₋₄ alkynyl , C₂₋₄ haloalkenyl, C₂₋₄ haloalkynyl, C₃₋₈ cycloalkyl, C₃₋₈ cycloalkyloxy, C₃₋₈ cycloalkyl, NRARB, C (= O) R, C (= NOR) R or C (= NH) -OR; RA, RB are, independently of one another, hydrogen, C₁₋₄ alkyl, C₂₋₄ alkenyl, C₂₋₄ alkynyl, phenyl, benzyl, C₃₋₈ cycloalkyl, C₃₋₈ or C (= O) -R cycloalkenyl; R is hydrogen, OH, NH₂, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₂₋₄ alkenyl, C₂₋₄ alkynyl, C₁₋₄ alkoxy, C₁₋₄ haloalkoxy, C₁₋₄ alkylamino or di (C₁₋₄ alkyl) Not me; R is hydrogen, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₂₋₄ alkenyl, C₂₋₄ alkynyl or C₁₋₄ alkoxy-C₁₋₄ alkyl, R is hydrogen or C₁₋₄ alkyl; R is hydrogen, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₁₋₄ alkoxy, C₁₋₄ haloalkoxy, C₁₋₄ alkoxy-C₁₋₄ alkyl, C₁₋₄ haloalkoxy-C₁₋₄ alkyl, C₂₋₄ alkenyl, haloalkenyl C₂₋₄, C₂₋₄ alkynyl, C₂₋₄ haloalkynyl, CN, CH₂CN, NRARB or CH₂-OC (= O) R; R¹, R² are, independently of one another, hydrogen, halogen, OH, CN, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₁₋₄ alkoxy, C₁₋₄ haloalkoxy, C₁₋₄ alkoxy-C₁₋₄ alkyl, C₁₋ haloalkoxy ₄-C₁₋₄ alkyl, C₂₋₄ alkenyl, C₂₋₄ haloalkenyl, C₂₋₄ alkynyl, C₂₋₄ haloalkynyl, C₃₋₈ cycloalkyl, C₃₋₈ cycloalkyloxy, C₃₋₈ cycloalkyl-C₁₋₄ alkyl, NRARB, C (= O) R, C (= NOR) R, C (= NH) -OR or benzyl, wherein the phenyl portion of benzyl is unsubstituted or has 1, 2, 3, 4 or 5 substituents selected from the group consisting in CN, halogen, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₁₋₄ alkoxy, C₁₋₄ haloalkoxy, (C₁₋₄ alkoxy) carbonyl and di (C₁₋₄ alkyl) aminocarbonyl, or two radicals R¹ and R² which are together with the same carbon atom they form, together with said carbon atom, a saturated or partially unsaturated carbocycle of 3, 4, 5, 6 or 7 members or a saturated or partial heterocycle Highly unsaturated 3, 4, 5, 6 or 7 members, wherein the ring member atoms of the aforementioned heterocycle include, in addition to carbon atoms, 1, 2, 3 or 4 heteroatoms selected from the group of N, O and S , and wherein the aforementioned cycle is unsubstituted or has 1, 2, 3 or 4 substituents selected from halogen, CN, OH, SH, C₁₋₄ alkyl, C₁₋₄ alkoxy or C₁₋₄ alkylthio; and one or two CH₂ groups of the aforementioned cycles may be replaced by one or two groups C (= O) or C (= S), respectively; n indicates the amount of substituents Rᵇ in the phenyl ring, and n is 0, 1, 2, 3 or 4; Rᵇ is halogen, CN, NO₂, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₁₋₄ alkoxy, C₁₋₄ haloalkoxy, C₂₋₄ alkenyl, C₂₋₄ haloalkenyl, C₂₋₄ alkynyl, C₂₋₄ haloalkynyl, NRARB, C (= NOR) R or C (= NH) -OR, where it is possible for n = 2, 3 or 4 that Rᵇ be identical or different; Het is a 5- or 6-membered heteroaryl, wherein the heteroaryl ring member atoms include, in addition to carbon atoms, 1, 2, 3 or 4 heteroatoms selected from the group of N, O and S and where the heteroaryl is unsubstituted or has 1, 2, 3 or 4 identical or different Rᶜ groups: Rᶜ is halogen, CN, NO₂, C alquilo alkyl, C₁₋₆ haloalkyl, C₁₋₆ alkoxy, C₁₋₆ haloalkoxy, C₁₋₆ alkylthio, C₁₋₆ haloalkylthio, C₁₋₆ alkylsulfinyl, C₁₋₆ haloalkylsulfinyl, C₁₋₆ alkylsulfonyl, C₁₋₆ haloalkylsulfonyl, C₁₋₆ alkoxy-C₁₋₄ alkyl, C₁₋₆ haloalkoxy-C₁₋₄ alkyl, C₂₋₆ alkenyl, C₂₋₆ alkynyl, NRARB, C (= O) R, C (= NOR) R, C (= NH) -OR, C₃₋₈ cycloalkyl, C₃₋₈ cycloalkyl-C alquilo alkyl, phenyl, phenyl-C₁ alkyl ₋₄, phenoxy, phenoxy-C₁₋₄ alkyl or a 5- or 6-membered heteroaryl, wherein the heteroaryl ring member atoms include, in addition to carbon atoms, 1, 2, 3 or 4 heteroatoms selected from the group of N, O and S, and wherein the aforementioned cyclic radicals are unsubstituted or have 1, 2, 3 or 4 identical or different Rᵈ substituents: Rᵈ is halogen, CN, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₁₋₄ alkoxy or C₁₋₄ haloalkoxy; or two radicals Rᶜ that bind to the adjacent ring member atoms of the Het group form, together with said ring member atoms, a fused, saturated, partially unsaturated or aromatic carbocycle or heterocycle of 5, 6 or 7 members, wherein the Fused heterocycle ring member atoms include, in addition to carbon atoms, 1, 2, 3 or 4 heteroatoms selected from the group of N, O and S, and wherein the fused carbocycle or heterocycle is unsubstituted or has 1, 2, 3 or 4 identical or different Rᵉ radical groups: Rᵉ is halogen, CN, C₁₋₄ alkyl, C₁₋₄ haloalkyl, C₁₋₄ alkoxy or C₁₋₄ haloalkoxy; and the N-oxides and salts thereof acceptable in agriculture.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12153758 | 2012-02-03 | ||
EP12154196 | 2012-02-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR089882A1 true AR089882A1 (en) | 2014-09-24 |
Family
ID=47624098
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP130100327 AR089883A1 (en) | 2012-02-03 | 2013-02-01 | PIRIMIDINE FUNGICIDES COMPOUND |
ARP130100325 AR089881A1 (en) | 2012-02-03 | 2013-02-01 | PIRIMIDINE FUNGICIDE COMPOUNDS |
ARP130100326 AR089882A1 (en) | 2012-02-03 | 2013-02-01 | PIRIMIDINE FUNGICIDE COMPOUNDS |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP130100327 AR089883A1 (en) | 2012-02-03 | 2013-02-01 | PIRIMIDINE FUNGICIDES COMPOUND |
ARP130100325 AR089881A1 (en) | 2012-02-03 | 2013-02-01 | PIRIMIDINE FUNGICIDE COMPOUNDS |
Country Status (2)
Country | Link |
---|---|
AR (3) | AR089883A1 (en) |
WO (3) | WO2013113788A1 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3760617B1 (en) | 2012-10-25 | 2023-03-22 | Shenyang Sinochem Agrochemicals R&D Co., Ltd. | Substituted pyrimidine compound and uses thereof |
US20160221964A1 (en) * | 2013-09-16 | 2016-08-04 | Basf Se | Fungicidal pyrimidine compounds |
CN105753791B (en) * | 2014-12-19 | 2019-09-13 | 沈阳中化农药化工研发有限公司 | Substituted uracil compound and application thereof |
CN111789120B (en) * | 2020-07-29 | 2022-04-01 | 湖南省植物保护研究所 | Bactericide imazalil ionic liquid, and preparation method and application thereof |
Family Cites Families (112)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3325503A (en) | 1965-02-18 | 1967-06-13 | Diamond Alkali Co | Polychloro derivatives of mono- and dicyano pyridines and a method for their preparation |
US3296272A (en) | 1965-04-01 | 1967-01-03 | Dow Chemical Co | Sulfinyl- and sulfonylpyridines |
JPS54115388A (en) | 1978-03-01 | 1979-09-07 | Nippon Chemiphar Co Ltd | Acetic acid derivative and its preparation |
GB2059955A (en) | 1979-09-13 | 1981-04-29 | Merck & Co Inc | Process for preparing methylvanillyl ketone |
DE3338292A1 (en) | 1983-10-21 | 1985-05-02 | Basf Ag, 6700 Ludwigshafen | 7-AMINO-AZOLO (1,5-A) -PYRIMIDINE AND FUNGICIDES CONTAINING THEM |
CA1249832A (en) | 1984-02-03 | 1989-02-07 | Shionogi & Co., Ltd. | Azolyl cycloalkanol derivatives and agricultural fungicides |
BR8600161A (en) | 1985-01-18 | 1986-09-23 | Plant Genetic Systems Nv | CHEMICAL GENE, HYBRID, INTERMEDIATE PLASMIDIO VECTORS, PROCESS TO CONTROL INSECTS IN AGRICULTURE OR HORTICULTURE, INSECTICIDE COMPOSITION, PROCESS TO TRANSFORM PLANT CELLS TO EXPRESS A PLANTINIDE TOXIN, PRODUCED BY CULTURES, UNITED BY BACILLA |
DE3545319A1 (en) | 1985-12-20 | 1987-06-25 | Basf Ag | ACRYLIC ACID ESTERS AND FUNGICIDES THAT CONTAIN THESE COMPOUNDS |
CN1015981B (en) | 1986-05-02 | 1992-03-25 | 施托福化学公司 | Fungicidal pyridyl imidates |
ATE82966T1 (en) | 1986-08-12 | 1992-12-15 | Mitsubishi Chem Ind | PYRIDINECARBOXAMIDE DERIVATIVES AND THEIR USE AS A FUNGICIDE. |
US4895849A (en) | 1986-10-08 | 1990-01-23 | Ube Industries, Ltd. | Aralkylaminopyrimidine compounds which are useful as for producing thereof and insecticides |
DE3642452A1 (en) * | 1986-12-12 | 1988-06-23 | Bayer Ag | SUBSTITUTED 4-AMINO-PYRIMIDINE |
EP0374753A3 (en) | 1988-12-19 | 1991-05-29 | American Cyanamid Company | Insecticidal toxines, genes coding therefor, antibodies binding them, transgenic plant cells and plants expressing these toxines |
EP0392225B1 (en) | 1989-03-24 | 2003-05-28 | Syngenta Participations AG | Disease-resistant transgenic plants |
ATE121267T1 (en) | 1989-11-07 | 1995-05-15 | Pioneer Hi Bred Int | LARVAE-KILLING LECTINS AND BASED PLANT RESISTANCE AGAINST INSECTS. |
US6187773B1 (en) | 1989-11-10 | 2001-02-13 | Agro-Kanesho Co., Ltd. | Hexahydrotriazine compounds and insecticides |
EP0519211A1 (en) * | 1991-05-17 | 1992-12-23 | Hoechst Schering AgrEvo GmbH | Substituted 4-aminopyrimidine, process for their preparation and their use as parasiticide |
JP2828186B2 (en) | 1991-09-13 | 1998-11-25 | 宇部興産株式会社 | Acrylate-based compounds, their preparation and fungicides |
UA48104C2 (en) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Dna fragment including sequence that codes an insecticide protein with optimization for corn, dna fragment providing directed preferable for the stem core expression of the structural gene of the plant related to it, dna fragment providing specific for the pollen expression of related to it structural gene in the plant, recombinant dna molecule, method for obtaining a coding sequence of the insecticide protein optimized for corn, method of corn plants protection at least against one pest insect |
US5439911A (en) | 1992-12-28 | 1995-08-08 | Shionogi & Co., Ltd. | Aminopyrimidine derivatives and their production and use |
BR9408475A (en) | 1994-01-07 | 1997-08-26 | Dowelanco | N- (4-pyrimidinyl) amides pesticides |
DE69500091T2 (en) | 1994-02-01 | 1997-05-15 | Ube Industries | 4-phenylamino-pyrimidine derivatives, process for their preparation and pesticides for agriculture and horticulture containing them |
US5530195A (en) | 1994-06-10 | 1996-06-25 | Ciba-Geigy Corporation | Bacillus thuringiensis gene encoding a toxin active against insects |
DE19518073A1 (en) | 1995-05-17 | 1996-11-21 | Hoechst Ag | Substituted benzyloxycarbonylguanidines, process for their preparation, their use as a medicament or diagnostic agent and medicament containing them |
DE19603576A1 (en) | 1996-02-01 | 1997-08-07 | Bayer Ag | Acylated 4-amino and 4-hydrazinopyrimidines |
JPH1036355A (en) | 1996-07-19 | 1998-02-10 | Ube Ind Ltd | Production of 4-amino-5-chloro-6-(1-fluoroehyl)pyrimidine derivative |
DE19650197A1 (en) | 1996-12-04 | 1998-06-10 | Bayer Ag | 3-thiocarbamoylpyrazole derivatives |
TW460476B (en) | 1997-04-14 | 2001-10-21 | American Cyanamid Co | Fungicidal trifluoromethylalkylamino-triazolopyrimidines |
KR100644301B1 (en) | 1997-09-18 | 2006-11-10 | 바스프 악티엔게젤샤프트 | Benzamidoxim Derivatives, Intermediate Products and Methods for Preparing and Using Them as Fungicides |
DE19750012A1 (en) | 1997-11-12 | 1999-05-20 | Bayer Ag | Isothiazole carboxamides |
BR9813376A (en) | 1997-12-04 | 2001-06-19 | Dow Agrosciences Llc | Fungicide composition and methods and compounds for their preparation |
AU2006201959B2 (en) | 1997-12-22 | 2008-09-04 | Bayer Healthcare Llc | Inhibition of Raf Kinase using Substituted Heterocyclic Ureas |
SK286264B6 (en) | 1998-11-17 | 2008-06-06 | Kumiai Chemical Industry Co., Ltd. | Pyrimidinylbenzimidazole or triazinylbenzimidazole derivatives, intermediates for preparing them and agricultural/horticultural fungicides containing them |
IT1303800B1 (en) | 1998-11-30 | 2001-02-23 | Isagro Ricerca Srl | DIPEPTID COMPOUNDS HAVING HIGH FUNGICIDE AND AGRICULTURAL USE. |
JP3417862B2 (en) | 1999-02-02 | 2003-06-16 | 新東工業株式会社 | Silica gel highly loaded with titanium oxide photocatalyst and method for producing the same |
AU770077B2 (en) | 1999-03-11 | 2004-02-12 | Dow Agrosciences Llc | Heterocyclic substituted isoxazolidines and their use as fungicides |
US6586617B1 (en) | 1999-04-28 | 2003-07-01 | Sumitomo Chemical Takeda Agro Company, Limited | Sulfonamide derivatives |
UA73307C2 (en) | 1999-08-05 | 2005-07-15 | Куміаі Кемікал Індастрі Ко., Лтд. | Carbamate derivative and fungicide of agricultural/horticultural destination |
DE10021412A1 (en) | 1999-12-13 | 2001-06-21 | Bayer Ag | Fungicidal active ingredient combinations |
PT1250047E (en) | 2000-01-25 | 2005-08-31 | Syngenta Participations Ag | HERBICIDE COMPOSITION |
US6376548B1 (en) | 2000-01-28 | 2002-04-23 | Rohm And Haas Company | Enhanced propertied pesticides |
IL167956A (en) | 2000-02-04 | 2009-02-11 | Sumitomo Chemical Co | Isocyanate compound |
DE60111236T2 (en) | 2000-08-25 | 2006-04-27 | Syngenta Participations Ag | HYBRIDING CRYSTAL PROTEINS FROM BACILLUS THURIGIENSIS |
MXPA03002338A (en) | 2000-09-18 | 2003-09-10 | Du Pont | Pyridinyl amides and imides for use as fungicides. |
AU2002228640B2 (en) | 2000-11-17 | 2005-11-10 | Dow Agrosciences Llc | Compounds having fungicidal activity and processes to make and use same |
JP5034142B2 (en) | 2001-04-20 | 2012-09-26 | 住友化学株式会社 | Plant disease control composition |
DE10136065A1 (en) | 2001-07-25 | 2003-02-13 | Bayer Cropscience Ag | pyrazolylcarboxanilides |
AR037228A1 (en) | 2001-07-30 | 2004-11-03 | Dow Agrosciences Llc | ACID COMPOUNDS 6- (ARIL OR HETEROARIL) -4-AMYNOPYCOLINIC, HERBICIDE COMPOSITION THAT UNDERSTANDS AND METHOD TO CONTROL UNWANTED VEGETATION |
FR2828196A1 (en) | 2001-08-03 | 2003-02-07 | Aventis Cropscience Sa | New iodochromone derivatives, useful for the prevention or cure of plant fungal disorders, especially in cereals, vines, fruits, legumes or ornamental plants |
AU2002327096B2 (en) | 2001-08-17 | 2007-11-22 | Sankyo Agro Company, Limited | 3-phenoxy-4-pyridazinol derivative and herbicide composition containing the same |
US7230167B2 (en) | 2001-08-31 | 2007-06-12 | Syngenta Participations Ag | Modified Cry3A toxins and nucleic acid sequences coding therefor |
WO2003052073A2 (en) | 2001-12-17 | 2003-06-26 | Syngenta Participations Ag | Novel corn event |
WO2003053145A1 (en) | 2001-12-21 | 2003-07-03 | Nissan Chemical Industries, Ltd. | Bactericidal composition |
TWI327462B (en) | 2002-01-18 | 2010-07-21 | Sumitomo Chemical Co | Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same |
US20030166476A1 (en) | 2002-01-31 | 2003-09-04 | Winemiller Mark D. | Lubricating oil compositions with improved friction properties |
DE10204390A1 (en) | 2002-02-04 | 2003-08-14 | Bayer Cropscience Ag | Disubstituted thiazolylcarboxanilides |
CA2477931C (en) | 2002-03-05 | 2011-02-01 | Josef Ehrenfreund | O-cyclopropyl-carboxanilides and their use as fungicides |
DE60321207D1 (en) | 2002-09-19 | 2008-07-03 | Lilly Co Eli | Diaryläther als opioid-rezeptor antagonisten |
GB0227966D0 (en) | 2002-11-29 | 2003-01-08 | Syngenta Participations Ag | Organic Compounds |
WO2004083193A1 (en) | 2003-03-17 | 2004-09-30 | Sumitomo Chemical Company, Limited | Amide compound and bactericide composition containing the same |
EP1635822A4 (en) | 2003-06-25 | 2009-06-24 | Elan Pharm Inc | Methods and compositions for treating rheumatoid arthritis |
WO2005011601A2 (en) | 2003-08-01 | 2005-02-10 | Pfizer Products, Inc. | 6-menbered heteroaryl compounds for the treatment of neurodegenerative disorders |
WO2005014534A1 (en) | 2003-08-08 | 2005-02-17 | Transtech Pharma, Inc. | Aryl and heteroaryl compounds, compositions, and methods of use |
TWI355894B (en) | 2003-12-19 | 2012-01-11 | Du Pont | Herbicidal pyrimidines |
RS51454B (en) | 2004-03-10 | 2011-04-30 | Basf Se | 5,6-dialkyl-7-amino-triazolopyrimidines, method for their production, their use for controlling pathogenic fungi and agents containing said compounds |
AP2006003778A0 (en) | 2004-03-10 | 2006-10-31 | Basf Ag | 5,6-Dialkyl-7-amino-triazolopyrimidines, method for their production, their use for controlling pat hogenic fungi and agents containing said compounds |
NZ549673A (en) | 2004-03-30 | 2010-03-26 | Taisho Pharmaceutical Co Ltd | Pyrimidine derivatives and methods of treatment related to the use thereof |
US7459562B2 (en) | 2004-04-23 | 2008-12-02 | Bristol-Myers Squibb Company | Monocyclic heterocycles as kinase inhibitors |
CA2564813A1 (en) | 2004-06-03 | 2005-12-22 | E.I. Du Pont De Nemours And Company | Fungicidal mixtures of amidinylphenyl compounds |
BRPI0512118A (en) | 2004-06-18 | 2008-02-06 | Basf Ag | compound, process to combat harmful fungi, and fungicidal agent |
EP1761499B1 (en) | 2004-06-18 | 2010-02-24 | Basf Se | 1-methyl-3-trifluoromethyl-pyrazole-4-carboxylic acid (ortho-phenyl)-anilides and to use thereof as fungicide |
GB0418048D0 (en) | 2004-08-12 | 2004-09-15 | Syngenta Participations Ag | Method for protecting useful plants or plant propagation material |
WO2006072831A1 (en) | 2005-01-10 | 2006-07-13 | Pfizer Inc. | Pyrrolopyrazoles, potent kinase inhibitors |
JP4966866B2 (en) | 2005-01-14 | 2012-07-04 | エフ.ホフマン−ラ ロシュ アーゲー | Thiazole-4-carboxamide derivatives as mGluR5 antagonists |
DE102005007160A1 (en) | 2005-02-16 | 2006-08-24 | Basf Ag | Pyrazolecarboxylic acid anilides, process for their preparation and compositions containing them for controlling harmful fungi |
DE502006001074D1 (en) | 2005-02-16 | 2008-08-21 | Basf Se | 5-ALKOXYALKYL-6-ALKYL-7-AMINO-AZOLOPYRIMIDINE, METHOD FOR THE PRODUCTION THEREOF, AND ITS USE FOR THE CONTROL OF HARMFUL FUNGI AND THE MEDIUM CONTAINING THE SAME |
DE102005009458A1 (en) | 2005-03-02 | 2006-09-07 | Bayer Cropscience Ag | pyrazolylcarboxanilides |
AU2006223461A1 (en) | 2005-03-09 | 2006-09-21 | Schering Corporation | Fused thieno (2, 3-B) pyridine and thiazolo (5, 4-B) pyridine compounds for inhibiting ksp kinesin activity |
US20070021435A1 (en) | 2005-06-10 | 2007-01-25 | Gaul Michael D | Aminopyrimidines as kinase modulators |
GB0513841D0 (en) | 2005-07-07 | 2005-08-10 | Medivir Ab | Cysteine protease inhibitors |
CN101208316B (en) | 2005-08-15 | 2012-05-09 | 贝林格尔·英格海姆国际有限公司 | Method for producing betamimetics |
GB0516705D0 (en) | 2005-08-15 | 2005-09-21 | Syngenta Participations Ag | Process |
EP1937691A1 (en) | 2005-10-21 | 2008-07-02 | Dow Agrosciences LLC | Thieno-pyrimidine compounds having fungicidal activity |
TWI382974B (en) | 2005-12-20 | 2013-01-21 | Incyte Corp | N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase |
CN101360713B (en) | 2006-01-13 | 2012-08-15 | 美国陶氏益农公司 | 6-(poly-substituted aryl)-4-aminopicolinates and their use as herbicides |
EP1983832A2 (en) | 2006-02-09 | 2008-10-29 | Syngeta Participations AG | A method of protecting a plant propagation material, a plant, and/or plant organs |
CA2643670A1 (en) | 2006-02-27 | 2007-08-30 | Sterix Limited | Diaryl compounds as non-steroidal inhibitors of 17-beta hydroxysteroid dehydrogenase and/or steroid sulphatase for the treatment of oestrogen-related diseases such as hormone dependent breast cancer |
MX2009002781A (en) | 2006-09-15 | 2009-03-30 | Reviva Pharmaceuticals Inc | Synthesis, methods of using, and compositions of cycloalkylmethylamines. |
US8779154B2 (en) | 2006-09-26 | 2014-07-15 | Qinglin Che | Fused ring compounds for inflammation and immune-related uses |
WO2008039882A1 (en) | 2006-09-30 | 2008-04-03 | Sanofi-Aventis U.S. Llc | A combination of niacin and a prostaglandin d2 receptor antagonist |
ES2302447B1 (en) | 2006-10-20 | 2009-06-12 | Laboratorios Almirall S.A. | DERIVATIVES OF 4- (2-AMINO-1-HYDROXYETHYL) Phenol as agonists of the BETA2 ADRENERGIC RECEIVER. |
TW200831488A (en) | 2006-11-29 | 2008-08-01 | Astrazeneca Ab | Novel compounds |
PE20081559A1 (en) | 2007-01-12 | 2008-11-20 | Merck & Co Inc | SPIROCHROMANONE DERIVATIVES SUBSTITUTED AS ACETYL COA CARBOXYLASE INHIBITORS |
EP2132203A1 (en) | 2007-04-10 | 2009-12-16 | Bristol-Myers Squibb Company | Thiazolyl compounds useful as kinase inhibitors |
WO2008156726A1 (en) | 2007-06-20 | 2008-12-24 | Merck & Co., Inc. | Inhibitors of janus kinases |
CL2009000130A1 (en) | 2008-01-22 | 2010-11-05 | Dow Agrosciences Llc | Compounds derived from 5-fluoro-pyrimidine; fungicidal composition comprising said compounds; and method for the control or prevention of a fungal attack on a plant. |
NZ590070A (en) | 2008-06-24 | 2012-02-24 | Sanofi Aventis | Substituted isoquinolines and isoquinolinones as rho kinase inhibitors |
DE102008040168A1 (en) | 2008-07-04 | 2010-01-07 | Robert Bosch Gmbh | Solenoid valve for a fuel injector and fuel injector |
US20100068197A1 (en) | 2008-07-11 | 2010-03-18 | Myriad Pharmaceuticals, Inc. | Pharmaceutical compounds as inhibitors of cell proliferation and the use thereof |
US8268843B2 (en) | 2008-08-29 | 2012-09-18 | Dow Agrosciences, Llc. | 5,8-difluoro-4-(2-(4-(heteroaryloxy)-phenyl)ethylamino)quinazolines and their use as agrochemicals |
EP2344458A1 (en) | 2008-09-11 | 2011-07-20 | Pfizer Inc. | Heteroaryls amide derivatives and their use as glucokinase activators |
AR074209A1 (en) | 2008-11-24 | 2010-12-29 | Boehringer Ingelheim Int | USEFUL PYRIMIDINE DERIVATIVES FOR CANCER TREATMENT |
EP2210890A1 (en) | 2009-01-19 | 2010-07-28 | Almirall, S.A. | Oxadiazole derivatives as S1P1 receptor agonists |
NZ596304A (en) | 2009-05-28 | 2014-01-31 | Novartis Ag | Substituted aminopropionic derivatives as neprilysin inhibitors |
US8461164B2 (en) | 2009-08-31 | 2013-06-11 | Dow Agrosciences, Llc. | Pteridines and their use as agrochemicals |
WO2011025505A1 (en) | 2009-08-31 | 2011-03-03 | Dow Agrosciences Llc | Pteridines and their use as agrochemicals |
EA019396B1 (en) | 2009-09-01 | 2014-03-31 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Synergistic fungicidal compositions containing a 5-fluoropyrimidine derivative for fungal control in cereals |
EP2477976A4 (en) | 2009-09-18 | 2013-03-13 | Boehringer Ingelheim Int | Quinazolinone derivatives as viral polymerase inhibitors |
US8841486B2 (en) | 2009-10-30 | 2014-09-23 | Aton Pharma | Stereoselective synthesis of metyrosine |
KR101781663B1 (en) | 2010-01-13 | 2017-09-25 | 템페로 파마슈티칼즈, 인크. | Compounds for inhibiting histone deacetylase enzymes and methods of making the same |
JP2013519673A (en) | 2010-02-10 | 2013-05-30 | レクシコン ファーマシューティカルズ インコーポレイテッド | Tryptophan hydroxylase inhibitors for the treatment of metastatic bone disease |
CN102260263A (en) | 2010-05-26 | 2011-11-30 | 四川大学 | Diphenylamine purine derivatives, and preparation method and medicinal application thereof |
-
2013
- 2013-01-31 WO PCT/EP2013/051855 patent/WO2013113788A1/en active Application Filing
- 2013-01-31 WO PCT/EP2013/051854 patent/WO2013113787A1/en active Application Filing
- 2013-01-31 WO PCT/EP2013/051859 patent/WO2013113791A1/en active Application Filing
- 2013-02-01 AR ARP130100327 patent/AR089883A1/en unknown
- 2013-02-01 AR ARP130100325 patent/AR089881A1/en unknown
- 2013-02-01 AR ARP130100326 patent/AR089882A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2013113791A1 (en) | 2013-08-08 |
AR089883A1 (en) | 2014-09-24 |
WO2013113788A1 (en) | 2013-08-08 |
AR089881A1 (en) | 2014-09-24 |
WO2013113787A1 (en) | 2013-08-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR089889A1 (en) | PIRIMIDINE FUNGICIDE COMPOUNDS | |
AR100312A1 (en) | DIAMINOTRIAZINE COMPOUNDS | |
AR106763A1 (en) | OXADIAZOLS REPLACED TO FIGHT FITOPATHOGEN FUNGI | |
AR101586A1 (en) | HETEROCYCLIC DERIVATIVES WITH SUBSTITUTES CONTAINING SULFUR ASSETS AS PESTICIDES | |
AR091710A1 (en) | COMPOSITIONS PESTICIDES AND PROCESSES RELATED TO THE SAME | |
AR100171A1 (en) | DIAMINOTRIAZINE COMPOUNDS AND ITS USE AS A HERBICIDE | |
AR099287A1 (en) | DERIVATIVES OF CONDENSED BICYCLIC HETEROCICLES SUBSTITUTED WITH 2- (HET) ARILO AS AGENTS TO COMBAT PARASITES | |
AR105322A1 (en) | HITEROCICLES NITROGENATED AS PESTICIDES | |
EA201891409A1 (en) | BENZAMIDE COMPOUNDS AND THEIR APPLICATION AS HERBICIDES | |
AR100051A1 (en) | DIAMINOTRIAZINE COMPOUNDS | |
AR089884A1 (en) | PIRIMIDINE FUNGICIDE COMPOUNDS | |
AR100170A1 (en) | DIAMINOTRIAZINE COMPOUNDS | |
AR110724A1 (en) | HETEROCYCLIC DERIVATIVES AS PESTICIDES | |
AR092313A1 (en) | N-SUBSTITUTED AND DERIVATIVE HETEROBICICLIC COMPOUNDS TO COMBAT ANIMAL PESTS II | |
AR090350A1 (en) | CHEMICAL COMPOUNDS | |
AR093628A1 (en) | COMPOUNDS OF 2- [PHENOXY-PHENYL] -1- [1,2,4] TRIAZOL-1-IL-ETHANOL REPLACED AND ITS USE AS FUNGICIDES | |
AR106873A1 (en) | PIRIDINE COMPOUNDS AS FUNGICIDES | |
AR107955A1 (en) | DERIVATIVES OF PIRIDINO- / PIRIMIDINO-PIRIDINA, WITH HERBICITY ACTIVITY | |
AR093629A1 (en) | COMPOUNDS OF 2- [PHENOXY-PHENYL] -1- [1,2,4] TRIAZOL-1-IL-ETHANOL REPLACED AND ITS USE AS FUNGICIDES | |
AR088320A1 (en) | ISOINDOLINONE AND PIRROLOPIRIDINONE DERIVATIVES AS AKT INHIBITORS | |
AR089882A1 (en) | PIRIMIDINE FUNGICIDE COMPOUNDS | |
AR094160A1 (en) | FUNGICIDE COMPOUNDS OF IMIDAZOLILO AND TRIAZOLILO | |
AR089887A1 (en) | PIRIMIDINE FUNGICIDE COMPOUNDS | |
AR093630A1 (en) | COMPOUNDS OF [1,2,4] SUBSTITUTED TRIAZOL | |
AR090335A1 (en) | PIRIMIDINE FUNGUITED COMPOUNDS |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB | Suspension of granting procedure |