AR085961A1 - Polisacaridos que poseen dos sitios de union a la antitrombina iii, metodo para prepararlos y composiciones farmaceuticas que los contienen - Google Patents
Polisacaridos que poseen dos sitios de union a la antitrombina iii, metodo para prepararlos y composiciones farmaceuticas que los contienenInfo
- Publication number
- AR085961A1 AR085961A1 ARP120101220A ARP120101220A AR085961A1 AR 085961 A1 AR085961 A1 AR 085961A1 AR P120101220 A ARP120101220 A AR P120101220A AR P120101220 A ARP120101220 A AR P120101220A AR 085961 A1 AR085961 A1 AR 085961A1
- Authority
- AR
- Argentina
- Prior art keywords
- bond
- polysaccharide
- saccharide unit
- hexasaccharide
- formula
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000004676 glycans Chemical class 0.000 abstract 6
- 229920001282 polysaccharide Polymers 0.000 abstract 6
- 239000005017 polysaccharide Substances 0.000 abstract 6
- 150000001720 carbohydrates Chemical group 0.000 abstract 4
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 102000004411 Antithrombin III Human genes 0.000 abstract 1
- 108090000935 Antithrombin III Proteins 0.000 abstract 1
- 229960005348 antithrombin iii Drugs 0.000 abstract 1
- 229940127217 antithrombotic drug Drugs 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 229960002897 heparin Drugs 0.000 abstract 1
- 229920000669 heparin Polymers 0.000 abstract 1
- 239000002628 heparin derivative Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
- B01D15/3823—Affinity chromatography of other types, e.g. avidin, streptavidin or biotin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
- B01D15/1878—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series for multi-dimensional chromatography
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Materials Engineering (AREA)
- Dermatology (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1153116 | 2011-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR085961A1 true AR085961A1 (es) | 2013-11-06 |
Family
ID=46025830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP120101220A AR085961A1 (es) | 2011-04-11 | 2012-04-10 | Polisacaridos que poseen dos sitios de union a la antitrombina iii, metodo para prepararlos y composiciones farmaceuticas que los contienen |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9346894B2 (enExample) |
| EP (1) | EP2697265B1 (enExample) |
| JP (1) | JP6122418B2 (enExample) |
| AR (1) | AR085961A1 (enExample) |
| TW (1) | TW201247209A (enExample) |
| UY (1) | UY34012A (enExample) |
| WO (1) | WO2012140580A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2818871A1 (en) * | 2013-06-28 | 2014-12-31 | Roche Diagniostics GmbH | Means and methods for universal calibration of anti-Factor Xa tests |
| CN103743837B (zh) * | 2013-12-24 | 2015-01-21 | 山东泰邦生物制品有限公司 | 人抗凝血酶ⅲ肝素结合比例检测方法 |
| KR102240937B1 (ko) * | 2014-10-10 | 2021-04-15 | 삼성디스플레이 주식회사 | 표시 장치 |
| US20170317516A1 (en) * | 2014-11-06 | 2017-11-02 | Mantisvision Ltd. | Circuit to provide energy pulses |
| EP3398971A4 (en) * | 2015-12-30 | 2019-09-25 | Shenzhen Hepalink Pharmaceutical Group Co., Ltd. | SULFATED HEPARINOLIGOSACCHARIDE AND MANUFACTURING METHOD AND APPLICATION THEREOF |
| CN111175415A (zh) * | 2019-12-24 | 2020-05-19 | 湖北亿诺瑞生物制药有限公司 | 一种依诺肝素钠中苄索氯铵残留的测定方法 |
| CA3237396A1 (en) | 2021-08-08 | 2023-02-16 | University Of Rochester | Nanomembrane device and method for biomarker sampling |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2663639B1 (fr) | 1990-06-26 | 1994-03-18 | Rhone Poulenc Sante | Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation. |
| FR2845686B1 (fr) | 2002-10-10 | 2013-08-30 | Aventis Pharma Sa | Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant |
| US20040171819A1 (en) | 2002-10-10 | 2004-09-02 | Aventis Pharma S.A. | Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them |
| FR2889078B1 (fr) | 2005-07-27 | 2007-11-02 | Aventis Pharma Sa | Nouvelle methode de chromatographie d'affinite d'antithrombine iii |
-
2012
- 2012-04-10 AR ARP120101220A patent/AR085961A1/es not_active Application Discontinuation
- 2012-04-11 TW TW101112840A patent/TW201247209A/zh unknown
- 2012-04-11 US US14/111,300 patent/US9346894B2/en not_active Expired - Fee Related
- 2012-04-11 EP EP12718395.2A patent/EP2697265B1/en active Active
- 2012-04-11 JP JP2014504429A patent/JP6122418B2/ja active Active
- 2012-04-11 WO PCT/IB2012/051768 patent/WO2012140580A1/en not_active Ceased
- 2012-04-11 UY UY0001034012A patent/UY34012A/es not_active Application Discontinuation
-
2016
- 2016-04-21 US US15/135,010 patent/US20160310521A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2697265A1 (en) | 2014-02-19 |
| TW201247209A (en) | 2012-12-01 |
| JP2014511929A (ja) | 2014-05-19 |
| WO2012140580A1 (en) | 2012-10-18 |
| UY34012A (es) | 2012-11-30 |
| EP2697265B1 (en) | 2018-09-26 |
| US20160310521A1 (en) | 2016-10-27 |
| JP6122418B2 (ja) | 2017-04-26 |
| US20140031316A1 (en) | 2014-01-30 |
| US9346894B2 (en) | 2016-05-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2016007759A (es) | Uso de eteres de poli-alfa-1,3-glucano como modificadores de la viscosidad. | |
| BR112014005134A2 (pt) | composição farmacêutica de dissolução rápida | |
| BR112013028832A2 (pt) | composição alimentícia, uso de éter de celulose e método para melhorar uma ou mais das propriedades de uma composição alimentícia | |
| AR086543A1 (es) | Inhibidores de galectina-3 y metodos de uso de los mismos, composicion farmaceutica | |
| BR112015013124A2 (pt) | novos derivados de piridina | |
| CL2013001433A1 (es) | Composicion que comprende al menos una n-acetil lactosamina, al menos un oligosacarido sialilado al menos un oligosacarido fucosilado; y su uso en la prevencion de infecciones respiratorias agudas y/o para aliviar los sintomas de dichas infecciones. | |
| EA201501032A1 (ru) | Фармацевтическая композиция, способы лечения и ее применения | |
| BR112012031343A2 (pt) | compostos de heteroarila contendo nitrogênio | |
| BRPI0611872B8 (pt) | reagente polimérico, conjugado, método para preparação de um conjugado e composição farmacêutica | |
| CL2012002195A1 (es) | Composicion inmunogénica que comprende una mezcla de conjugados de polisacaridos-proteina multivalente que consiste en polisacáridos capsulares de streptococcus pneumoniae; metodo para inducir una respuesta inmune a un polisacarido capsular de streptococcus pneumoniae. | |
| BR112013016204A2 (pt) | composições de ingredientes ativos solúveis em gordura que contêm complexos de proteína vegetal-polissacarídeo de soja. | |
| MX360107B (es) | Formulación de acción rápida de insulina que comprende un compuesto aniónico sustituido. | |
| UA113005C2 (uk) | Біотехнологічний хондроїтин-6-сульфат з низькою молекулярною масою для запобігання остеоартриту | |
| PE20142325A1 (es) | Composiciones derivadas de la quitosana | |
| BR112016010072A8 (pt) | conjugado, composição farmacêutica, usos do conjugado ou da composição farmacêutica, e de polissacarídeo de vi fragmentado, e, método para a fabricação de um conjugado | |
| NZ624749A (en) | A sulfated polysaccharide compound and the preparation and use thereof | |
| MX340983B (es) | Composiciones farmaceuticas y nutraceuticas de acido abscisico. | |
| Mohamed et al. | Synthetic approaches to L-iduronic acid and L-idose: Key building blocks for the preparation of glycosaminoglycan oligosaccharides | |
| BR112014010047A8 (pt) | novos derivados de pirazina | |
| WO2012154680A3 (en) | MODIFIED AND DERIVATIZED β-GLUCAN COMPOUNDS, COMPOSITIONS, AND METHODS | |
| CY1115780T1 (el) | Φαρμακευτικη συνθεση με glycosαμινοglycans και χρηση αυτης για την θεραπεια χρονιων ελκων | |
| MX2012007662A (es) | Compuestos anti-heparina. | |
| BR112012023623A2 (pt) | agentes osmóticos de polissacarídeos esterificados | |
| BR112014003264A8 (pt) | composições nutricionais compreendendo uma fibra viscosa solúvel e um extrato de planta contendo polifenol | |
| CR10371A (es) | Compuestos heterociclicos apropiados para tratar trastornos que responden a la moduilacion del receptor de serotonina 5ht6 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |