CL2013001433A1 - Composicion que comprende al menos una n-acetil lactosamina, al menos un oligosacarido sialilado al menos un oligosacarido fucosilado; y su uso en la prevencion de infecciones respiratorias agudas y/o para aliviar los sintomas de dichas infecciones. - Google Patents
Composicion que comprende al menos una n-acetil lactosamina, al menos un oligosacarido sialilado al menos un oligosacarido fucosilado; y su uso en la prevencion de infecciones respiratorias agudas y/o para aliviar los sintomas de dichas infecciones.Info
- Publication number
- CL2013001433A1 CL2013001433A1 CL2013001433A CL2013001433A CL2013001433A1 CL 2013001433 A1 CL2013001433 A1 CL 2013001433A1 CL 2013001433 A CL2013001433 A CL 2013001433A CL 2013001433 A CL2013001433 A CL 2013001433A CL 2013001433 A1 CL2013001433 A1 CL 2013001433A1
- Authority
- CL
- Chile
- Prior art keywords
- infections
- oligosaccharide
- relieve
- symptoms
- prevention
- Prior art date
Links
- 229920001542 oligosaccharide Polymers 0.000 title 2
- 150000002482 oligosaccharides Chemical class 0.000 title 2
- KFEUJDWYNGMDBV-UHFFFAOYSA-N (N-Acetyl)-glucosamin-4-beta-galaktosid Natural products OC1C(NC(=O)C)C(O)OC(CO)C1OC1C(O)C(O)C(O)C(CO)O1 KFEUJDWYNGMDBV-UHFFFAOYSA-N 0.000 title 1
- KFEUJDWYNGMDBV-LODBTCKLSA-N N-acetyllactosamine Chemical compound O[C@@H]1[C@@H](NC(=O)C)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KFEUJDWYNGMDBV-LODBTCKLSA-N 0.000 title 1
- HESSGHHCXGBPAJ-UHFFFAOYSA-N N-acetyllactosamine Natural products CC(=O)NC(C=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O HESSGHHCXGBPAJ-UHFFFAOYSA-N 0.000 title 1
- 206010057190 Respiratory tract infections Diseases 0.000 title 1
- 230000001154 acute effect Effects 0.000 title 1
- 208000015181 infectious disease Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 208000024891 symptom Diseases 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pediatric Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10192230A EP2465509A1 (en) | 2010-11-23 | 2010-11-23 | Oligosaccharide composition for treating acute respiratory tract infections |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2013001433A1 true CL2013001433A1 (es) | 2013-12-13 |
Family
ID=43728675
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2013001433A CL2013001433A1 (es) | 2010-11-23 | 2013-05-17 | Composicion que comprende al menos una n-acetil lactosamina, al menos un oligosacarido sialilado al menos un oligosacarido fucosilado; y su uso en la prevencion de infecciones respiratorias agudas y/o para aliviar los sintomas de dichas infecciones. |
Country Status (13)
Country | Link |
---|---|
US (1) | US9763465B2 (es) |
EP (2) | EP2465509A1 (es) |
CN (1) | CN103582485A (es) |
AU (1) | AU2011340882B2 (es) |
BR (1) | BR112013012598A2 (es) |
CA (1) | CA2818012A1 (es) |
CL (1) | CL2013001433A1 (es) |
IL (1) | IL226348A0 (es) |
MX (1) | MX343321B (es) |
RU (1) | RU2593321C2 (es) |
SG (1) | SG190323A1 (es) |
TW (1) | TW201302205A (es) |
WO (1) | WO2012076323A1 (es) |
Families Citing this family (35)
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NZ611807A (en) | 2010-12-31 | 2015-02-27 | Abbott Lab | Methods for decreasing the incidence of necrotizing enterocolitis in infants, toddlers, or children using human milk oligosaccharides |
EP3473257A1 (en) | 2010-12-31 | 2019-04-24 | Abbott Laboratories | Methods of using human milk oligosaccharides for improving airway respiratory health |
MX352040B (es) | 2010-12-31 | 2017-11-07 | Abbott Lab | Formulaciones nutricionales que incluyen los oligosacaridos de leche humana y los acidos grasos poliinsaturados de cadena larga y usos de las mismas. |
CN110051676A (zh) | 2010-12-31 | 2019-07-26 | 雅培制药有限公司 | 用于调节炎症的人乳寡糖 |
CA2822497C (en) | 2010-12-31 | 2020-07-28 | Abbott Laboratories | Methods for reducing the incidence of oxidative stress using human milk oligosaccharides, vitamin c and anti-inflammatory agents |
EP3510873A1 (en) | 2010-12-31 | 2019-07-17 | Abbott Laboratories | Nutritional compositions comprising human milk oligosaccharides and nucleotides and uses thereof for treating and/or preventing enteric viral infection |
MX355780B (es) | 2010-12-31 | 2018-04-30 | Abbott Lab | Fórmula pediátrica sintética para estimular células nerviosas entéricas en el tracto gastrointestinal. |
DK2734210T3 (en) | 2011-07-22 | 2018-01-22 | Abbott Lab | GALACTOOLIGOSACCHARIDES FOR THE PREVENTION OF DAMAGE TO AND / OR PROMOTION OF HEALING OF THE MAVE GAS CHANNEL |
BR112014004772A2 (pt) | 2011-08-29 | 2017-03-21 | Abbott Lab | oligossacarídeos do leite humano para evitar danos e/ou promover a cura do trato gastrointestinal |
EP2745705A1 (en) * | 2012-12-18 | 2014-06-25 | Abbott Laboratories | Nutritional use of human milk oligosaccharides |
US20150050245A1 (en) * | 2013-08-14 | 2015-02-19 | Tntgamble, Inc. | Methods and delivery system for beneficial additive and subtractive biological agents to promote balanced mammalian gastrointestinal flora |
AU2014350419B2 (en) * | 2013-11-15 | 2019-10-24 | Société des Produits Nestlé S.A. | Compositions for preventing or treating allergies in infants from or fed by non secretor mothers by providing fucosylated-oligosaccharides in particular among infants at risk or born by C-section |
ES2857077T3 (es) * | 2013-11-15 | 2021-09-28 | Nestle Sa | Composiciones para su uso en la prevención o tratamiento de infecciones del TRS en bebés o niños jóvenes en riesgo |
CN107249611A (zh) | 2014-10-24 | 2017-10-13 | 进化生物系统股份有限公司 | 活化的双歧杆菌及其应用方法 |
US10328091B2 (en) * | 2014-10-31 | 2019-06-25 | Nestec S.A. | Composition comprising Fut2-dependent oligosaccharides and Lacto-N-neotetraose for use in promoting brain development and cognition |
US10881674B2 (en) | 2014-12-08 | 2021-01-05 | Glycom A/S | Synthetic composition for treating metabolic disorders |
US10987368B2 (en) | 2014-12-08 | 2021-04-27 | Glycom A/S | Synthetic composition for preventing or treating CVD |
US10835544B2 (en) | 2014-12-08 | 2020-11-17 | Glycom A/S | Synthetic composition for regulating satiety |
WO2016091265A1 (en) * | 2014-12-08 | 2016-06-16 | Glycom A/S | Synthetic composition for treating metabolic disorders |
CN107405354A (zh) * | 2015-03-05 | 2017-11-28 | 格礼卡姆股份公司 | 治疗急性呼吸道感染的组合物和方法 |
AU2016227596B2 (en) * | 2015-03-05 | 2020-01-16 | Société des Produits Nestlé S.A. | Compositions for use in improving stool consistency or frequency in infants or young children |
WO2016139328A1 (en) * | 2015-03-05 | 2016-09-09 | Nestec S.A. | Compositions for use in the prevention or treatment of otitis or bronchitis in infants or young children |
WO2017103850A1 (en) * | 2015-12-15 | 2017-06-22 | Glycom A/S | Mixture of hmos |
CN105725216A (zh) * | 2016-03-15 | 2016-07-06 | 天津普生源科技发展有限公司 | 一种含有gaba的助眠功能食品及其制备方法 |
JP2019523278A (ja) * | 2016-07-28 | 2019-08-22 | フォンテラ コ−オペレイティブ グループ リミティド | 乳製品およびプロセス |
CN109640702A (zh) * | 2016-09-07 | 2019-04-16 | 雀巢产品技术援助有限公司 | 用于婴儿和/或幼儿的包含低聚糖的营养组合物 |
US11260067B2 (en) | 2017-05-24 | 2022-03-01 | Societe Des Produits Nestle S.A. | Methods and compositions for decreasing concentrations of detrimental proteolytic metabolites, treating health disorders, and/or promoting health benefits in infants or young children |
CN109043542A (zh) * | 2018-09-11 | 2018-12-21 | 内蒙古伊利实业集团股份有限公司 | 人乳寡糖和/或其前体在制备预防儿童龋齿疾病的组合物中的应用 |
WO2020161113A1 (en) * | 2019-02-04 | 2020-08-13 | N.V. Nutricia | Fermented formula with non digestible oligosaccharides for sleep improvement |
CA3135177A1 (en) * | 2019-04-09 | 2020-10-15 | Alexander Martinez | Immunomodulatory oligosaccharides for the treatment of pain |
JP7516053B2 (ja) * | 2020-01-20 | 2024-07-16 | 森永乳業株式会社 | 組成物並びに飲食品組成物、栄養組成物および調製乳 |
US11331329B2 (en) * | 2020-05-13 | 2022-05-17 | Glycosyn LLC | Fucosylated oligosaccharides for prevention of coronavirus infection |
WO2022226311A1 (en) * | 2021-04-23 | 2022-10-27 | Abbott Laboratories | Nutritional compositions comprising human milk oligosaccharides and a designed lipid component for improving lung function |
AU2022420738A1 (en) * | 2021-12-20 | 2024-05-30 | Société des Produits Nestlé S.A. | Secretory iga-biotic complexes and uses thereof |
JP2024004736A (ja) * | 2022-06-29 | 2024-01-17 | 雪印メグミルク株式会社 | 気管支炎を予防するための栄養組成物 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
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WO1991016449A1 (en) | 1990-04-16 | 1991-10-31 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
US5545553A (en) | 1994-09-26 | 1996-08-13 | The Rockefeller University | Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them |
US6045854A (en) * | 1997-03-31 | 2000-04-04 | Abbott Laboraties | Nutritional formulations containing oligosaccharides |
EP1062873A1 (en) * | 1999-12-13 | 2000-12-27 | N.V. Nutricia | Improved infant formula, protein hydrolysate for use in such an infant formula, and method for producing such a hydrolysate |
US6630452B2 (en) * | 2000-02-17 | 2003-10-07 | Wyeth | Nutritional formulation containing prebiotic substances |
ATE503007T1 (de) * | 2003-11-19 | 2011-04-15 | Nestec Sa | Isolierte bakteriophage und ihre verwendung in lebensmitteln oder zur sanierung der fabrik- umgebung |
CA2548140A1 (en) * | 2003-12-05 | 2005-06-23 | University Of Massachusetts | Oligosaccharide compositions and use thereof in the treatment of infection |
ATE361101T1 (de) * | 2004-08-24 | 2007-05-15 | Nutricia Nv | Nahrungszusammensetzung die unverdauliche oligosaccharide enthält |
CA2652517A1 (en) * | 2006-06-13 | 2007-12-21 | Nestec S.A. | Prevention and treatment of otitis media with non-pathogenic bacterial strains |
EP2044851A1 (en) | 2007-09-26 | 2009-04-08 | Nestec S.A. | Prevention of allergy at weaning |
EP2060257A1 (en) * | 2007-11-08 | 2009-05-20 | Nestec S.A. | Prevention and treatment of secondary infections following viral infection |
SG185948A1 (en) * | 2007-11-08 | 2012-12-28 | Nestec Sa | Use of oligosaccharides containing n-acetyllactosamine for maturation of immune responses in neonates |
EP2072052A1 (en) | 2007-12-17 | 2009-06-24 | Nestec S.A. | Prevention of opportunistic infections in immune-compromised subjects |
WO2011008087A1 (en) * | 2009-07-15 | 2011-01-20 | N.V. Nutricia | Fucosyllactose as breast milk identical non-digestible oligosaccharide with new functional benefit |
EP2465507A1 (en) * | 2010-11-23 | 2012-06-20 | Nestec S.A. | Oligosaccharide composition for treating skin diseases |
EP2465508A1 (en) * | 2010-11-23 | 2012-06-20 | Nestec S.A. | Composition comprising hydrolysed proteins and oligosaccharides for treating skin diseases |
EP2454948A1 (en) * | 2010-11-23 | 2012-05-23 | Nestec S.A. | Oligosaccharide mixture and food product comprising this mixture, especially infant formula |
-
2010
- 2010-11-23 EP EP10192230A patent/EP2465509A1/en not_active Withdrawn
-
2011
- 2011-11-21 BR BR112013012598A patent/BR112013012598A2/pt not_active IP Right Cessation
- 2011-11-21 EP EP11784695.6A patent/EP2643006A1/en not_active Withdrawn
- 2011-11-21 RU RU2013128570/15A patent/RU2593321C2/ru active
- 2011-11-21 US US13/988,975 patent/US9763465B2/en active Active
- 2011-11-21 SG SG2013038179A patent/SG190323A1/en unknown
- 2011-11-21 MX MX2013005727A patent/MX343321B/es active IP Right Grant
- 2011-11-21 CN CN201180056475.7A patent/CN103582485A/zh active Pending
- 2011-11-21 WO PCT/EP2011/070563 patent/WO2012076323A1/en active Application Filing
- 2011-11-21 CA CA2818012A patent/CA2818012A1/en not_active Abandoned
- 2011-11-21 AU AU2011340882A patent/AU2011340882B2/en active Active
- 2011-11-23 TW TW100142957A patent/TW201302205A/zh unknown
-
2013
- 2013-05-13 IL IL226348A patent/IL226348A0/en unknown
- 2013-05-17 CL CL2013001433A patent/CL2013001433A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2011340882A1 (en) | 2013-05-30 |
EP2465509A1 (en) | 2012-06-20 |
CA2818012A1 (en) | 2012-06-14 |
TW201302205A (zh) | 2013-01-16 |
MX343321B (es) | 2016-11-01 |
CN103582485A (zh) | 2014-02-12 |
SG190323A1 (en) | 2013-06-28 |
BR112013012598A2 (pt) | 2016-08-09 |
EP2643006A1 (en) | 2013-10-02 |
MX2013005727A (es) | 2013-07-03 |
RU2593321C2 (ru) | 2016-08-10 |
US20130236424A1 (en) | 2013-09-12 |
AU2011340882B2 (en) | 2016-10-20 |
US9763465B2 (en) | 2017-09-19 |
IL226348A0 (en) | 2013-07-31 |
RU2013128570A (ru) | 2014-12-27 |
WO2012076323A1 (en) | 2012-06-14 |
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