AR080497A1 - Heterociclos radiomarcados con yodo,utiles para diagnosticar la enfermedad de alzheimer - Google Patents
Heterociclos radiomarcados con yodo,utiles para diagnosticar la enfermedad de alzheimerInfo
- Publication number
- AR080497A1 AR080497A1 ARP110100767A ARP110100767A AR080497A1 AR 080497 A1 AR080497 A1 AR 080497A1 AR P110100767 A ARP110100767 A AR P110100767A AR P110100767 A ARP110100767 A AR P110100767A AR 080497 A1 AR080497 A1 AR 080497A1
- Authority
- AR
- Argentina
- Prior art keywords
- iodine
- disease
- useful
- diagnosing alzheimer
- radiomarced
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
- C07B59/002—Heterocyclic compounds
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Compuestos radiomarcados con yodo que son utiles para diagnosticar la enfermedad de Alzheimer. Precursores respectivos para la síntesis de dichos compuestos. Proceso agentes para el diagnostico por imágenes para manufacturar dichos. Reivindicacion 1: Un compuesto caracterizado porque es de formula (1), donde - Q es un anillo aromático de seis miembros, carbocíclico o bien heterociclo con un átomo de N, donde X1, X2, X3, X4 y X5 se seleccionan en forma independiente entre N o C, y donde cero o uno de X1, X2, X3, X4 o X5 es N y los restantes son C; - A es Sn(alquilo)3, I, I-123, I-124, I-125, I-131, o bien Br; alquilo comprende metilo, etilo, propilo, butilo, pentilo y hexilo, - Y es C o N; con la condicion de que si X1, X2, X3, X4 o X5 tiene el valor N, se excluye la sustitucion con A en esa posicion; o una sal farmacéuticamente aceptable del mismo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10075112 | 2010-03-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR080497A1 true AR080497A1 (es) | 2012-04-11 |
Family
ID=43969390
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP110100767A AR080497A1 (es) | 2010-03-11 | 2011-03-11 | Heterociclos radiomarcados con yodo,utiles para diagnosticar la enfermedad de alzheimer |
Country Status (3)
| Country | Link |
|---|---|
| AR (1) | AR080497A1 (es) |
| TW (1) | TW201134492A (es) |
| WO (1) | WO2011110511A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103724207B (zh) * | 2013-12-20 | 2016-07-06 | 北京智博高科生物技术有限公司 | 苯基苄基醚类衍生物及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY27003A1 (es) * | 2000-11-06 | 2002-07-31 | Schering Ag | Productos radiofarmacéuticos para el diagnóstico de la enfermedad de alzheimer |
| EP2163541A1 (en) * | 2008-09-12 | 2010-03-17 | Bayer Schering Pharma Aktiengesellschaft | Piperazine derivatives for binding and imaging amyloid plaques and their use |
-
2011
- 2011-03-07 WO PCT/EP2011/053353 patent/WO2011110511A1/en active Application Filing
- 2011-03-11 TW TW100108422A patent/TW201134492A/zh unknown
- 2011-03-11 AR ARP110100767A patent/AR080497A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW201134492A (en) | 2011-10-16 |
| WO2011110511A1 (en) | 2011-09-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |