AR079033A1 - Procedimiento de purificacion del factor b - Google Patents

Procedimiento de purificacion del factor b

Info

Publication number
AR079033A1
AR079033A1 ARP100104216A ARP100104216A AR079033A1 AR 079033 A1 AR079033 A1 AR 079033A1 AR P100104216 A ARP100104216 A AR P100104216A AR P100104216 A ARP100104216 A AR P100104216A AR 079033 A1 AR079033 A1 AR 079033A1
Authority
AR
Argentina
Prior art keywords
factor
fraction
purification procedure
iii
subject
Prior art date
Application number
ARP100104216A
Other languages
English (en)
Original Assignee
Lab Francais Du Fractionnement
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lab Francais Du Fractionnement filed Critical Lab Francais Du Fractionnement
Publication of AR079033A1 publication Critical patent/AR079033A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La solicitud se refiere a un procedimiento de purificacion del factor B, que comprende las etapas que consisten en: (i) obtener una fraccion de plasma sanguíneo que contiene el factor B; (ii) someter la fraccion obtenida en la etapa (i) a una cromatografía por afinidad de tipo heparina; (iii) someter la fraccion enriquecida en factor B obtenida en la etapa (ii) a una cromatografía de intercambio de cationes; (iv) someter la fraccion enriquecida en factor B obtenida en la etapa (iii) a una cromatografía de intercambio de aniones, (v) eluir el factor B. (Figura 1). Reivindicacion 10: Preparacion de acuerdo con a reivindicacion 9, caracterizada porque dicha preparacion está en forma liofilizada.
ARP100104216A 2009-11-16 2010-11-15 Procedimiento de purificacion del factor b AR079033A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0958047A FR2952639B1 (fr) 2009-11-16 2009-11-16 Procede de purification de facteur b

Publications (1)

Publication Number Publication Date
AR079033A1 true AR079033A1 (es) 2011-12-21

Family

ID=42316132

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100104216A AR079033A1 (es) 2009-11-16 2010-11-15 Procedimiento de purificacion del factor b

Country Status (5)

Country Link
US (1) US8729244B2 (es)
EP (1) EP2501401A1 (es)
AR (1) AR079033A1 (es)
FR (1) FR2952639B1 (es)
WO (1) WO2011058286A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014035876A1 (en) * 2012-08-27 2014-03-06 William Marsh Rice University Heat-inactivated complement factor b compositions and methods
FR3004451B1 (fr) * 2013-04-11 2015-12-11 Lab Francais Du Fractionnement Procede de preparation d'une solution de proteine c viralement securisee par une double etape de nanofiltration
CN108473530B (zh) * 2015-10-15 2022-12-23 普莱泽玛科技有限公司 从血浆中提取蛋白质的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920625A (en) * 1973-06-19 1975-11-18 Kabi Ab Isolation of coagulation factors from biological material using cross linked sulfated, sulfonated carbohydrates
FR2543448A1 (fr) * 1983-04-01 1984-10-05 Rhone Poulenc Spec Chim Procede de fractionnement du plasma
MX2009009200A (es) * 2007-03-01 2009-10-28 Advanced Vision Therapies Inc Tratamiento de enfermedades caracterizadas por la inflamacion.
ES2595059T3 (es) * 2007-03-20 2016-12-27 Csl Behring Gmbh Métodos para la producción a escala industrial de preparados terapéuticos del Factor H del complemento a partir de plasma humano

Also Published As

Publication number Publication date
FR2952639A1 (fr) 2011-05-20
US20120232253A1 (en) 2012-09-13
US8729244B2 (en) 2014-05-20
WO2011058286A1 (fr) 2011-05-19
FR2952639B1 (fr) 2013-08-30
EP2501401A1 (fr) 2012-09-26

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