AR076664A1 - Metodo para analizar mezclas peptidicas con espectometria de masas - Google Patents

Metodo para analizar mezclas peptidicas con espectometria de masas

Info

Publication number
AR076664A1
AR076664A1 ARP100101574A ARP100101574A AR076664A1 AR 076664 A1 AR076664 A1 AR 076664A1 AR P100101574 A ARP100101574 A AR P100101574A AR P100101574 A ARP100101574 A AR P100101574A AR 076664 A1 AR076664 A1 AR 076664A1
Authority
AR
Argentina
Prior art keywords
mixtures
peptidic
analyzing
mass spectrometry
mass spectometry
Prior art date
Application number
ARP100101574A
Other languages
English (en)
Inventor
Hardy Chan
Jentale Shiea
Yi-Tzu Cho
Chi-Hsien Lin
Original Assignee
Scinopharm Taiwan Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scinopharm Taiwan Ltd filed Critical Scinopharm Taiwan Ltd
Publication of AR076664A1 publication Critical patent/AR076664A1/es

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/285Demyelinating diseases; Multipel sclerosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Un método para caracterizar y clasificar una muestra de mezclas de péptidos o polipéptidos o una biomolécula que comprende un componente polipeptídico en el que se utiliza espectrometría de masa y métodos estadísticos de análisis de los resultados de la espectrometría de masa. Reivindicacion 2: Un método de acuerdo con la reivindicacion 1, caracterizado porque el método comprende (a) digerir o descomponer la muestra con una enzima o una sustancia química apropiada para obtener fragmentos peptídicos; (b) analizar los fragmentos peptídicos por espectrometría de masa para producir un espectro de masa; y (c) analizar el espectro de masa con métodos estadísticos para clasificar y distinguir las distintas muestras.
ARP100101574A 2009-05-08 2010-05-07 Metodo para analizar mezclas peptidicas con espectometria de masas AR076664A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17657909P 2009-05-08 2009-05-08

Publications (1)

Publication Number Publication Date
AR076664A1 true AR076664A1 (es) 2011-06-29

Family

ID=43050492

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100101574A AR076664A1 (es) 2009-05-08 2010-05-07 Metodo para analizar mezclas peptidicas con espectometria de masas

Country Status (11)

Country Link
US (1) US8497630B2 (es)
EP (1) EP2427199B1 (es)
JP (1) JP2012526288A (es)
KR (1) KR101696948B1 (es)
CN (1) CN102802640A (es)
AR (1) AR076664A1 (es)
AU (1) AU2010245773B2 (es)
BR (1) BRPI1011434A2 (es)
CA (1) CA2761406C (es)
IL (1) IL216223A0 (es)
WO (1) WO2010129851A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2010146489A (ru) 2008-04-16 2012-05-27 Момента Фармасьютикалз, Инк. (Us) Анализ композиций сополимера аминокислот
CN102112485B (zh) * 2008-08-07 2013-11-27 台湾神隆股份有限公司 乙酸格拉默(glatiramer acetate)的合成
WO2012123959A2 (en) 2011-02-14 2012-09-20 Usv Limited Copolymer-1, process for preparation and analytical methods thereof
WO2013009885A2 (en) 2011-07-11 2013-01-17 Momenta Pharmaceuticals, Inc. Evaluation of copolymer diethylamide
EP3232189A4 (en) * 2014-12-08 2017-12-13 Shimadzu Corporation Multidimensional mass spectrometry data processing device
CN112649537B (zh) * 2015-04-28 2024-03-29 深圳翰宇药业股份有限公司 多肽混合物高效液相色谱分析方法
WO2019049038A1 (en) * 2017-09-07 2019-03-14 Alembic Pharmaceuticals Limited PROCESS FOR THE CHARACTERIZATION OF GLATIRAMERATE ACETATE
US20200075128A1 (en) * 2018-09-03 2020-03-05 Scinopharm Taiwan, Ltd. Analyzing High Dimensional Data Based on Hypothesis Testing for Assessing the Similarity between Complex Organic Molecules Using Mass Spectrometry
EP3877071A4 (en) * 2018-11-09 2022-08-03 Nx Prenatal Inc. PAIRED COLUMN CHEMISTRY IN TANDEM OF HIGH-THROUGHPUT EXOSOME PROTEOMIC ANALYSIS

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6486868A (en) * 1987-09-30 1989-03-31 Shimadzu Corp Column for hydrolyzing protein
US5885841A (en) * 1996-09-11 1999-03-23 Eli Lilly And Company System and methods for qualitatively and quantitatively comparing complex admixtures using single ion chromatograms derived from spectroscopic analysis of such admixtures
AU2003212580A1 (en) * 2003-03-25 2004-10-18 Institut Suisse De Bioinformatique Method for comparing proteomes
JP2006522340A (ja) * 2003-04-02 2006-09-28 メルク エンド カムパニー インコーポレーテッド 質量分析データの分析法
WO2006083853A2 (en) * 2005-01-31 2006-08-10 Insilicos, Llc Methods of identification of biomarkers with mass spectrometry techniques
EP2013628B1 (en) * 2006-04-28 2016-01-06 Momenta Pharmaceuticals, Inc. Methods of evaluating peptide mixtures

Also Published As

Publication number Publication date
WO2010129851A1 (en) 2010-11-11
US8497630B2 (en) 2013-07-30
EP2427199A1 (en) 2012-03-14
BRPI1011434A2 (pt) 2016-03-15
KR20120031477A (ko) 2012-04-03
US20100285513A1 (en) 2010-11-11
CA2761406A1 (en) 2010-11-11
CN102802640A (zh) 2012-11-28
EP2427199A4 (en) 2013-03-06
EP2427199B1 (en) 2014-06-04
IL216223A0 (en) 2012-01-31
AU2010245773A1 (en) 2011-12-01
JP2012526288A (ja) 2012-10-25
AU2010245773B2 (en) 2014-03-20
KR101696948B1 (ko) 2017-01-16
CA2761406C (en) 2017-12-19

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