AR070005A1 - Derivados naftalenicos , su procedimiento de preparacion y las composiciones farmaceuticas que los contienen - Google Patents
Derivados naftalenicos , su procedimiento de preparacion y las composiciones farmaceuticas que los contienenInfo
- Publication number
- AR070005A1 AR070005A1 ARP080102856A ARP080102856A AR070005A1 AR 070005 A1 AR070005 A1 AR 070005A1 AR P080102856 A ARP080102856 A AR P080102856A AR P080102856 A ARP080102856 A AR P080102856A AR 070005 A1 AR070005 A1 AR 070005A1
- Authority
- AR
- Argentina
- Prior art keywords
- branched
- linear
- group
- disorders
- alkyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/32—Oximes
- C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C251/48—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a six-membered aromatic ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Psychology (AREA)
- Child & Adolescent Psychology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Reivindicacion 1: Compuestos de formula (1): en la que R1 representa un grupo un grupo alquilo C1-6 lineal o ramificado, alquenilo C1-6 lineal o ramificado, halogenoalquilo C1-6 lineal o ramificado, polihalogenoalquilo C1-6 lineal o ramificado, cicloalquilo C3-8, cicloalquil C3-8 alquilo C1-6 cuya parte alquilo puede ser lineal o ramificada, arilo, arilalquilo C1-6 cuya parte alquilo puede ser lineal o ramificada, heteroarilo o heteroarilalquilo C1-6 cuya parte alquilo puede ser lineal o ramificada, X representa un grupo N-OR2 en el que R2 representa un átomo de hidrogeno o un grupo alquilo C1-6 lineal o ramificado, entendiéndose que: la oxima =N-OR2 puede tener configuracion Z o E, por ôariloö, se entiende un grupo fenilo, naftilo o bifenilo, por ôheteroariloö, se entiende cualquier grupo aromático mono o bicíclico que contiene 1 a 3 heteroátomos elegidos entre oxígeno, azufre y nitrogeno, pudiendo estar los grupos arilo y heteroarilo así definidos sustituidos con 1 a 3 grupos elegidos entre alquilo C1-6 lineal o ramificado, alcoxi C1-6 lineal o ramificado, hidroxi, carboxi, formilo, nitro, ciano; halogenoalquilo C1-6 lineal o ramificado, polihalogenoalquilo C1-6 lineal o ramificado, alquiloxicarbonilo o átomos de halogeno, sus enantiomeros y diastereoisomeros, así como sus sales de adicion a un ácido o a una base aceptable farmacéuticamente. Reivindicacion 9: Composiciones farmacéuticas segun la reivindicacion 7 utiles para la fabricacion de medicamentos para el tratamiento de trastornos del sueno, estrés, ansiedad, depresion mayor o depresiones estacionales, patologías cardiovasculares, patologías del sistema digestivo, insomnios y fatigas debidos a diferencias horarias, esquizofrenia, ataques de pánico, melancolía, trastornos del apetito, obesidad, insomnio, trastornos psicoticos, epilepsia, diabetes, enfermedad de Parkinson, demencia senil, diversos trastornos asociados al envejecimiento normal o patologico, migrana, pérdidas de memoria, enfermedad de Alzheimer, trastornos de la circulacion cerebral, así como en las disfunciones sexuales, como inhibidores de la ovulacion, inmunomoduladores y en el tratamiento de los cánceres.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0704747A FR2918372B1 (fr) | 2007-07-02 | 2007-07-02 | Nouveaux derives naphtaleniques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR070005A1 true AR070005A1 (es) | 2010-03-10 |
Family
ID=38925714
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080102856A AR070005A1 (es) | 2007-07-02 | 2008-07-02 | Derivados naftalenicos , su procedimiento de preparacion y las composiciones farmaceuticas que los contienen |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7947852B2 (es) |
| EP (1) | EP2167460A2 (es) |
| JP (1) | JP2010531859A (es) |
| KR (1) | KR20100029262A (es) |
| CN (1) | CN101687777A (es) |
| AR (1) | AR070005A1 (es) |
| AU (1) | AU2008288373B2 (es) |
| BR (1) | BRPI0814402A2 (es) |
| CA (1) | CA2691586A1 (es) |
| EA (1) | EA201000083A1 (es) |
| FR (1) | FR2918372B1 (es) |
| MA (1) | MA31577B1 (es) |
| UA (1) | UA94828C2 (es) |
| WO (1) | WO2009022063A2 (es) |
| ZA (1) | ZA201000024B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102603545B (zh) * | 2012-02-10 | 2014-03-12 | 武汉万知生物医药有限公司 | 一种7-甲氧基-1-萘乙胺的制备方法 |
| FR3014433B1 (fr) * | 2013-12-05 | 2015-12-25 | Servier Lab | Nouveau procede de synthese du 7-methoxy-naphtalene-1-carbaldehyde et application a la synthese de l'agomelatine |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2689124A1 (fr) * | 1992-03-27 | 1993-10-01 | Adir | Nouvelles naphtylalkylamines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2737220B1 (fr) | 1995-07-24 | 1997-09-26 | Adir | Sequences nucleiques codant pour des recepteurs de la melatonine et leurs applications |
| FR2762598A1 (fr) * | 1997-04-25 | 1998-10-30 | Adir | Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennnent |
| FR2771739B1 (fr) * | 1997-11-28 | 2001-04-20 | Adir | Nouveaux composes naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP3841628B2 (ja) * | 1999-08-20 | 2006-11-01 | 武田薬品工業株式会社 | 経皮吸収剤 |
| FR2890562B1 (fr) * | 2005-09-09 | 2012-10-12 | Servier Lab | Utilisation de l'agomelatine pour l'obtention de medicaments destines au traitement des troubles du sommeil chez le patient deprime |
-
2007
- 2007-07-02 FR FR0704747A patent/FR2918372B1/fr not_active Expired - Fee Related
-
2008
- 2008-07-01 US US12/452,429 patent/US7947852B2/en not_active Expired - Fee Related
- 2008-07-01 CN CN200880022874A patent/CN101687777A/zh active Pending
- 2008-07-01 EP EP08827457A patent/EP2167460A2/fr not_active Withdrawn
- 2008-07-01 JP JP2010514037A patent/JP2010531859A/ja active Pending
- 2008-07-01 EA EA201000083A patent/EA201000083A1/ru unknown
- 2008-07-01 KR KR1020107002337A patent/KR20100029262A/ko not_active Application Discontinuation
- 2008-07-01 CA CA002691586A patent/CA2691586A1/fr not_active Abandoned
- 2008-07-01 BR BRPI0814402-8A patent/BRPI0814402A2/pt not_active IP Right Cessation
- 2008-07-01 UA UAA201000635A patent/UA94828C2/ru unknown
- 2008-07-01 AU AU2008288373A patent/AU2008288373B2/en not_active Ceased
- 2008-07-01 WO PCT/FR2008/000932 patent/WO2009022063A2/fr active Application Filing
- 2008-07-02 AR ARP080102856A patent/AR070005A1/es unknown
-
2010
- 2010-01-04 ZA ZA2010/00024A patent/ZA201000024B/en unknown
- 2010-02-01 MA MA32571A patent/MA31577B1/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2918372B1 (fr) | 2009-08-28 |
| ZA201000024B (en) | 2011-04-28 |
| WO2009022063A3 (fr) | 2009-04-16 |
| US20100168244A1 (en) | 2010-07-01 |
| JP2010531859A (ja) | 2010-09-30 |
| BRPI0814402A2 (pt) | 2015-08-04 |
| FR2918372A1 (fr) | 2009-01-09 |
| UA94828C2 (ru) | 2011-06-10 |
| CA2691586A1 (fr) | 2009-02-19 |
| EP2167460A2 (fr) | 2010-03-31 |
| CN101687777A (zh) | 2010-03-31 |
| KR20100029262A (ko) | 2010-03-16 |
| US7947852B2 (en) | 2011-05-24 |
| WO2009022063A2 (fr) | 2009-02-19 |
| AU2008288373B2 (en) | 2011-08-04 |
| AU2008288373A1 (en) | 2009-02-19 |
| EA201000083A1 (ru) | 2010-06-30 |
| MA31577B1 (fr) | 2010-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |