AR063927A1 - Procedimiento para la preparacion de 4, 4' -(1-metil-1,2-etandil)-bis- (2,6 -piperazindiona) - Google Patents
Procedimiento para la preparacion de 4, 4' -(1-metil-1,2-etandil)-bis- (2,6 -piperazindiona)Info
- Publication number
- AR063927A1 AR063927A1 ARP070105219A ARP070105219A AR063927A1 AR 063927 A1 AR063927 A1 AR 063927A1 AR P070105219 A ARP070105219 A AR P070105219A AR P070105219 A ARP070105219 A AR P070105219A AR 063927 A1 AR063927 A1 AR 063927A1
- Authority
- AR
- Argentina
- Prior art keywords
- formula
- compound
- preparation
- methyl
- roocch2
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 4
- ZHNUHDYFZUAESO-UHFFFAOYSA-N Formamide Chemical compound NC=O ZHNUHDYFZUAESO-UHFFFAOYSA-N 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 2
- 238000007363 ring formation reaction Methods 0.000 abstract 2
- AOHJOMMDDJHIJH-VKHMYHEASA-N (2s)-propane-1,2-diamine Chemical compound C[C@H](N)CN AOHJOMMDDJHIJH-VKHMYHEASA-N 0.000 abstract 1
- 125000005233 alkylalcohol group Chemical group 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- FOCAUTSVDIKZOP-UHFFFAOYSA-N chloroacetic acid Chemical compound OC(=O)CCl FOCAUTSVDIKZOP-UHFFFAOYSA-N 0.000 abstract 1
- 229940106681 chloroacetic acid Drugs 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA1958/2006A AT504621B1 (de) | 2006-11-24 | 2006-11-24 | Neues verfahren zur herstellung von 4,4'-(1-methyl -1,2-ethandiyl)-bis-(2,6-piperazindion) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR063927A1 true AR063927A1 (es) | 2009-02-25 |
Family
ID=39048046
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070105219A AR063927A1 (es) | 2006-11-24 | 2007-11-23 | Procedimiento para la preparacion de 4, 4' -(1-metil-1,2-etandil)-bis- (2,6 -piperazindiona) |
Country Status (24)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012081036A2 (en) * | 2010-12-13 | 2012-06-21 | Sequent Scientific Limited | A process for preparation of 4,4'-(1-methyl-1,2-ethandiyl)-bis-(2,6-piperazinedione) |
| CN102952088B (zh) * | 2012-06-26 | 2015-05-27 | 江苏奥赛康药业股份有限公司 | 右丙亚胺的制备方法 |
| CZ2013171A3 (cs) * | 2013-03-07 | 2014-04-30 | Ústav organické chemie a biochemie Akademie věd ČR, v. v. i. | Způsob výroby čistých bezvodých enantiomerů kyseliny 1,2-diaminopropan-N,N,N´,N´-tetraoctové |
| CN104177301B (zh) * | 2013-05-22 | 2016-04-13 | 江苏奥赛康药业股份有限公司 | 一种右丙亚胺的制备方法 |
| CN108250094B (zh) * | 2018-03-09 | 2021-01-26 | 江苏奥赛康药业有限公司 | 一种哌嗪二酮类化合物的制备方法 |
| CN110804022B (zh) * | 2019-11-06 | 2023-01-17 | 扬子江药业集团有限公司 | 一种右丙亚胺的制备方法 |
| CN113336661B (zh) * | 2020-03-03 | 2022-08-05 | 南京正大天晴制药有限公司 | 一种四乙酸甲酯类化合物的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2428353A (en) * | 1943-06-21 | 1947-10-07 | Frederick C Bersworth | Lower aliphatic esters of ethylene-and propylene-diamine n,n'-tetracetic acids |
| BE624685A (cg-RX-API-DMAC7.html) * | 1961-01-19 | |||
| NL273690A (cg-RX-API-DMAC7.html) | 1961-01-19 | 1900-01-01 | ||
| US3941790A (en) * | 1967-07-03 | 1976-03-02 | National Research Development Corporation | Bis diketopiperazines |
| JP2556026B2 (ja) * | 1986-04-03 | 1996-11-20 | 日産化学工業株式会社 | アルカリ廃水からの有用なカルボン酸の回収方法 |
| US4764614A (en) * | 1987-03-23 | 1988-08-16 | Monsanto Company | Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione) |
| JPS63243060A (ja) * | 1987-03-31 | 1988-10-07 | Nippon Mining Co Ltd | エステル化物の回収方法 |
| US4963679A (en) * | 1988-02-17 | 1990-10-16 | Erbamont, Inc. | Process for preparing bis (3,5-dioxopiperazinyl) alkanes or alkenes |
| GB9122677D0 (en) * | 1991-10-25 | 1991-12-11 | Eurocetus Bv | Process for preparing(s)(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione) |
| JPH11343267A (ja) * | 1998-05-28 | 1999-12-14 | Daikin Ind Ltd | 含ハロゲンカルボン酸エステルの製造方法 |
| WO2007053415A2 (en) * | 2005-11-01 | 2007-05-10 | Novartis Vaccines And Diagnostics Inc. | Agents for the treatment of cardiac arrhythmias |
-
2006
- 2006-11-24 AT ATA1958/2006A patent/AT504621B1/de not_active IP Right Cessation
-
2007
- 2007-11-22 PE PE2007001626A patent/PE20081497A1/es not_active Application Discontinuation
- 2007-11-23 KR KR1020097013026A patent/KR20090119828A/ko not_active Withdrawn
- 2007-11-23 UY UY30740A patent/UY30740A1/es not_active Application Discontinuation
- 2007-11-23 AR ARP070105219A patent/AR063927A1/es unknown
- 2007-11-23 CA CA002670282A patent/CA2670282A1/en not_active Abandoned
- 2007-11-23 EP EP07845264.6A patent/EP2099773B1/de active Active
- 2007-11-23 CN CN2007800467375A patent/CN101563329B/zh not_active Expired - Fee Related
- 2007-11-23 JP JP2009537442A patent/JP2010510253A/ja active Pending
- 2007-11-23 TW TW096144474A patent/TWI491607B/zh not_active IP Right Cessation
- 2007-11-23 WO PCT/AT2007/000529 patent/WO2008061270A1/de not_active Ceased
- 2007-11-23 MX MX2009005423A patent/MX2009005423A/es active IP Right Grant
- 2007-11-23 UA UAA200906599A patent/UA102509C2/uk unknown
- 2007-11-23 NZ NZ577293A patent/NZ577293A/en not_active IP Right Cessation
- 2007-11-23 BR BRPI0719153-7A2A patent/BRPI0719153A2/pt not_active IP Right Cessation
- 2007-11-23 US US12/516,348 patent/US8455641B2/en not_active Expired - Fee Related
- 2007-11-23 AU AU2007324322A patent/AU2007324322A1/en not_active Abandoned
- 2007-11-23 CL CL200703348A patent/CL2007003348A1/es unknown
- 2007-11-23 ES ES07845264.6T patent/ES2651245T3/es active Active
-
2009
- 2009-05-24 IL IL198908A patent/IL198908A0/en active IP Right Grant
- 2009-05-28 NO NO20092076A patent/NO20092076L/no not_active Application Discontinuation
- 2009-05-29 ZA ZA2009/03780A patent/ZA200903780B/en unknown
- 2009-06-19 MA MA32021A patent/MA31015B1/fr unknown
- 2009-06-23 CO CO09064950A patent/CO6220854A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN101563329B (zh) | 2013-03-13 |
| PE20081497A1 (es) | 2008-10-30 |
| TW200825068A (en) | 2008-06-16 |
| US8455641B2 (en) | 2013-06-04 |
| AT504621B1 (de) | 2014-08-15 |
| CN101563329A (zh) | 2009-10-21 |
| EP2099773B1 (de) | 2017-07-05 |
| UA102509C2 (uk) | 2013-07-25 |
| CA2670282A1 (en) | 2008-05-29 |
| WO2008061270A1 (de) | 2008-05-29 |
| ES2651245T3 (es) | 2018-01-25 |
| NO20092076L (no) | 2009-08-17 |
| UY30740A1 (es) | 2008-07-03 |
| JP2010510253A (ja) | 2010-04-02 |
| BRPI0719153A2 (pt) | 2014-02-04 |
| NZ577293A (en) | 2011-12-22 |
| MX2009005423A (es) | 2009-07-17 |
| CL2007003348A1 (es) | 2008-06-06 |
| IL198908A0 (en) | 2010-02-17 |
| AT504621A1 (de) | 2008-06-15 |
| RU2009123980A (ru) | 2010-12-27 |
| TWI491607B (zh) | 2015-07-11 |
| AU2007324322A1 (en) | 2008-05-29 |
| MA31015B1 (fr) | 2009-12-01 |
| US20100152447A1 (en) | 2010-06-17 |
| EP2099773A1 (de) | 2009-09-16 |
| KR20090119828A (ko) | 2009-11-20 |
| HK1133001A1 (en) | 2010-03-12 |
| ZA200903780B (en) | 2014-11-26 |
| CO6220854A2 (es) | 2010-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |