AR062391A1 - Uso de compuestos y derivados de 2,5 dihidroxibenceno para el tratamiento de dicracias hematologicas y cancer de un organo - Google Patents

Uso de compuestos y derivados de 2,5 dihidroxibenceno para el tratamiento de dicracias hematologicas y cancer de un organo

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Publication number
AR062391A1
AR062391A1 ARP070103635A ARP070103635A AR062391A1 AR 062391 A1 AR062391 A1 AR 062391A1 AR P070103635 A ARP070103635 A AR P070103635A AR P070103635 A ARP070103635 A AR P070103635A AR 062391 A1 AR062391 A1 AR 062391A1
Authority
AR
Argentina
Prior art keywords
treatment
cancer
organ
dihydroxibengen
dicracies
Prior art date
Application number
ARP070103635A
Other languages
English (en)
Inventor
Frutos Javier Angulo
Lopez Serafin Valverde
Sanchez Pedro Cuevas
Gallego Guillermo Gimenez
Puerto Rosa Maria Lozano
Garrido Antonio Romero
De Tejada Gorman Inigo Saenz
Original Assignee
Action Medicines Sl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES200602218A external-priority patent/ES2315118B1/es
Application filed by Action Medicines Sl filed Critical Action Medicines Sl
Publication of AR062391A1 publication Critical patent/AR062391A1/es

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07C309/24—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
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    • C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/41—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton
    • C07C309/42—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing singly-bound oxygen atoms bound to the carbon skeleton having the sulfo groups bound to carbon atoms of non-condensed six-membered aromatic rings
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    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
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    • C07C65/03—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups monocyclic and having all hydroxy or O-metal groups bound to the ring
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    • C07C65/19—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups having unsaturation outside the aromatic ring
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    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente se refiere al uso de un compuesto de formula (1) o una sal solvato, isomero o profármaco farmacéuticamente aceptables del mismo en la fabricacion de un medicamento para el tratamiento y/o profilaxis de discrasias hematologicas, incluyendo síndromes mielodisplásticos (SMDs) y para mejorar la eficacia de la quimioterapia, radioterapia y/o inmunoterapia contra el cáncer. Además, se refiere al uso de un compuesto de formula (1ö) en la fabricacion de un medicamento para el tratamiento y/o profilaxis de un cáncer de un organo.
ARP070103635A 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5 dihidroxibenceno para el tratamiento de dicracias hematologicas y cancer de un organo AR062391A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200602218A ES2315118B1 (es) 2006-08-16 2006-08-16 Uso de los compuestos y derivados 2,5-dihidroxibencenicos en la preparacion de medicamentos utiles en el tratamiento de rosacea y psoriasis.
ES200701856 2007-07-02

Publications (1)

Publication Number Publication Date
AR062391A1 true AR062391A1 (es) 2008-11-05

Family

ID=38613066

Family Applications (5)

Application Number Title Priority Date Filing Date
ARP070103635A AR062391A1 (es) 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5 dihidroxibenceno para el tratamiento de dicracias hematologicas y cancer de un organo
ARP070103641A AR062397A1 (es) 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5-dihidroxibenceno para el tratamiento de fibrosis
ARP070103646A AR062402A1 (es) 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5-dihidroxibenceno para el tratamiento del cancer de piel
ARP070103638A AR062394A1 (es) 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5-dihidroxibenceno para el tratamiento de la psoriasis
ARP070103636A AR062392A1 (es) 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5 dihidroxibenceno para el tratamiento de rosacea

Family Applications After (4)

Application Number Title Priority Date Filing Date
ARP070103641A AR062397A1 (es) 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5-dihidroxibenceno para el tratamiento de fibrosis
ARP070103646A AR062402A1 (es) 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5-dihidroxibenceno para el tratamiento del cancer de piel
ARP070103638A AR062394A1 (es) 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5-dihidroxibenceno para el tratamiento de la psoriasis
ARP070103636A AR062392A1 (es) 2006-08-16 2007-08-16 Uso de compuestos y derivados de 2,5 dihidroxibenceno para el tratamiento de rosacea

Country Status (8)

Country Link
US (15) US8541467B2 (es)
EP (4) EP2056814B1 (es)
AR (5) AR062391A1 (es)
CL (4) CL2007002390A1 (es)
ES (2) ES2491226T3 (es)
MX (2) MX2009001660A (es)
PT (2) PT2056814E (es)
WO (5) WO2008020027A2 (es)

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US8541467B2 (en) 2006-08-16 2013-09-24 Action Medicines, S.L. Use of 2,5-dihydroxybenzene compounds and derivatives for the treatment of hematological dyscrasias and cancer of an organ
PT2054051E (pt) * 2006-08-16 2013-04-03 Amderma Pharmaceuticals Llc Utilização de derivados 2,5-di-hidroxibenzeno para tratar ceratose actínica
WO2009103069A1 (en) 2008-02-15 2009-08-20 Osborne David W Skin penetration enhancing systems for polar drugs
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US8465413B2 (en) 2010-11-25 2013-06-18 Coloplast A/S Method of treating Peyronie's disease
ES2385160B1 (es) * 2010-12-23 2013-05-24 Italfármaco, S.A. Compuestos con actividad inhibitoria de factores de crecimiento de fibroblastos.
ES2410231B1 (es) * 2011-12-27 2014-04-29 Italfármaco S.A. Compuestos con actividad inhibitoria de factores de crecimiento de fibroblastos.
US9687465B2 (en) 2012-11-27 2017-06-27 Sol-Gel Technologies Ltd. Compositions for the treatment of rosacea
WO2015012978A1 (en) * 2013-07-22 2015-01-29 The Procter & Gamble Company Method of protecting skin from an environmental stressor
JP6606049B2 (ja) * 2015-10-28 2019-11-13 本田技研工業株式会社 自動運転システム及びナビケーションシステム
WO2017192928A1 (en) 2016-05-06 2017-11-09 Albany Medical College Treatment of rosacea with p38 and erk kinase pathway inhibitors
KR102178355B1 (ko) * 2018-10-19 2020-11-11 전남대학교산학협력단 심장 질환 치료용 조성물

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