AR061070A1 - Preparacion oral que comprende pioglitazona - Google Patents
Preparacion oral que comprende pioglitazonaInfo
- Publication number
- AR061070A1 AR061070A1 ARP070102205A ARP070102205A AR061070A1 AR 061070 A1 AR061070 A1 AR 061070A1 AR P070102205 A ARP070102205 A AR P070102205A AR P070102205 A ARP070102205 A AR P070102205A AR 061070 A1 AR061070 A1 AR 061070A1
- Authority
- AR
- Argentina
- Prior art keywords
- oral preparation
- pioglitazona
- understanding
- preparation understanding
- salt
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Abstract
Preparacion oral que enmascara suficientemente el sabor desagradable de la pioglitazona o una sal de la misma. La preparacion oral contiene pioglitazona o una sal de la misma y cloruro de metal alcalino.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006143390 | 2006-05-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR061070A1 true AR061070A1 (es) | 2008-07-30 |
Family
ID=38294162
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070102205A AR061070A1 (es) | 2006-05-23 | 2007-05-22 | Preparacion oral que comprende pioglitazona |
Country Status (15)
Country | Link |
---|---|
US (1) | US8865217B2 (es) |
EP (1) | EP2019669B1 (es) |
JP (1) | JP5162475B2 (es) |
KR (1) | KR20090024181A (es) |
CN (2) | CN101489538B (es) |
AR (1) | AR061070A1 (es) |
AT (1) | ATE534374T1 (es) |
CA (1) | CA2653786C (es) |
CL (1) | CL2007001457A1 (es) |
ES (1) | ES2377839T3 (es) |
HK (1) | HK1129566A1 (es) |
MY (1) | MY146781A (es) |
PE (1) | PE20080180A1 (es) |
TW (1) | TWI407959B (es) |
WO (1) | WO2007136129A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8722710B2 (en) | 2007-09-26 | 2014-05-13 | Deuterx, Llc | Deuterium-enriched pioglitazone |
US20120058205A1 (en) * | 2009-03-04 | 2012-03-08 | Walter Howard Peschel | Compositions and treatment regimes for reducing inflammation, end-organ injury, and/or systemic endotoxemia |
JPWO2010119851A1 (ja) * | 2009-04-14 | 2012-10-22 | ライオン株式会社 | 口腔内崩壊錠 |
DK2512455T3 (en) * | 2009-12-18 | 2014-03-24 | Frieslandcampina Nederland Holding B V | Co-treated tablet adjuvant composition, its preparation and use |
CN101912363A (zh) * | 2010-07-29 | 2010-12-15 | 蔡海德 | 溶解超滤-喷雾干燥-分子分散包衣-水化制粒-冷冻干燥生产脂质体组合药物 |
JP5630902B2 (ja) * | 2010-08-26 | 2014-11-26 | 沢井製薬株式会社 | ゾルピデム酒石酸塩含有口腔内崩壊錠の製造方法 |
EP2612657B1 (en) * | 2010-08-31 | 2023-08-09 | Kyowa Kirin Co., Ltd. | Orodispersible tablet |
TW201340998A (zh) * | 2012-02-29 | 2013-10-16 | Takeda Pharmaceutical | 經口劑 |
CA2941562C (en) | 2013-03-14 | 2021-09-21 | Deuterx, Llc | Deuterium-enriched 2,4-thiazolidinediones and methods of treatment |
EP3666273A3 (en) | 2014-01-15 | 2020-10-28 | Poxel SA | Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone |
JP6574556B2 (ja) * | 2014-08-27 | 2019-09-11 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
CN104174022B (zh) * | 2014-09-16 | 2018-10-16 | 过冬 | 一种吡格列酮的苦味抑制剂和包含吡格列酮的口服制剂 |
JP2018012697A (ja) * | 2016-07-11 | 2018-01-25 | 大原薬品工業株式会社 | 口腔内崩壊時間が短縮された、塩を含有する錠剤 |
US20210386726A1 (en) * | 2020-06-11 | 2021-12-16 | Chang Gung University | Method for inhibiting coronavirus infection and replication |
US11767317B1 (en) | 2020-06-30 | 2023-09-26 | Poxel Sa | Methods of synthesizing enantiopure deuterium-enriched pioglitazone |
US11319313B2 (en) | 2020-06-30 | 2022-05-03 | Poxel Sa | Crystalline forms of deuterium-enriched pioglitazone |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2809301B2 (ja) * | 1993-12-09 | 1998-10-08 | 田辺製薬株式会社 | 苦味隠蔽された経口投与製剤 |
CN1059320C (zh) * | 1994-04-07 | 2000-12-13 | 段永聚 | 一种无糖型草珊瑚含片 |
US7510728B2 (en) * | 2000-10-06 | 2009-03-31 | Takeda Pharmaceutical Company Limited | Solid preparations |
GB0027357D0 (en) * | 2000-11-09 | 2000-12-27 | Bradford Particle Design Plc | Particle formation methods and their products |
WO2003026586A2 (en) * | 2001-09-28 | 2003-04-03 | Teva Pharmaceutical Industries Ltd. | Pioglitazone hydrochloride |
JP2003183162A (ja) * | 2001-12-17 | 2003-07-03 | Sumitomo Pharmaceut Co Ltd | シメチジン経口製剤 |
US20030220374A1 (en) * | 2002-01-14 | 2003-11-27 | Pharmacia Corporation | Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors |
AU2003213338A1 (en) * | 2002-03-14 | 2003-09-22 | Daiichi Suntory Pharma Co., Ltd. | Tablet containing pilsicainide hydrochloride (dry) |
AU2003230719A1 (en) * | 2002-03-21 | 2003-10-08 | Teva Pharmaceutical Industries Ltd. | Fine particle size pioglitazone |
WO2004026241A2 (en) * | 2002-09-20 | 2004-04-01 | Andrx Labs Llc | Multistage formulation containing a biguanide and thiazolidindione derivatives |
KR20070011497A (ko) | 2004-05-11 | 2007-01-24 | 산텐 세이야꾸 가부시키가이샤 | 각결막 장해 치료제 |
KR100843508B1 (ko) * | 2004-09-29 | 2008-07-04 | 모리나가 뉴교 가부시키가이샤 | 고혈당 개선용 의약 |
AR058605A1 (es) | 2005-12-22 | 2008-02-13 | Takeda Pharmaceutical | Preparacion solida |
CL2007001194A1 (es) | 2006-04-27 | 2008-01-04 | Takeda Pharmaceutical | Preparacion farmaceutica solida que comprende particulas que comprenden (i) particulas de nucleo con excipiente y (ii) pioglitazona o una sal de la misma y un polimero soluble en acido, como copolimero de aminoalquil metacrilato e o dietilaminoacetato de polivinilacetal, ambos recubriendo el nucleo |
-
2007
- 2007-05-22 AT AT07744190T patent/ATE534374T1/de active
- 2007-05-22 ES ES07744190T patent/ES2377839T3/es active Active
- 2007-05-22 CN CN200780027567.6A patent/CN101489538B/zh not_active Expired - Fee Related
- 2007-05-22 MY MYPI20084689A patent/MY146781A/en unknown
- 2007-05-22 EP EP07744190A patent/EP2019669B1/en not_active Not-in-force
- 2007-05-22 KR KR1020087031329A patent/KR20090024181A/ko not_active Application Discontinuation
- 2007-05-22 JP JP2008553964A patent/JP5162475B2/ja active Active
- 2007-05-22 US US12/227,572 patent/US8865217B2/en not_active Expired - Fee Related
- 2007-05-22 CA CA2653786A patent/CA2653786C/en not_active Expired - Fee Related
- 2007-05-22 CN CN201310378591.1A patent/CN103520158B/zh not_active Expired - Fee Related
- 2007-05-22 WO PCT/JP2007/060756 patent/WO2007136129A1/en active Application Filing
- 2007-05-22 CL CL2007001457A patent/CL2007001457A1/es unknown
- 2007-05-22 AR ARP070102205A patent/AR061070A1/es unknown
- 2007-05-22 PE PE2007000630A patent/PE20080180A1/es not_active Application Discontinuation
- 2007-05-22 TW TW096118126A patent/TWI407959B/zh not_active IP Right Cessation
-
2009
- 2009-07-31 HK HK09107038.0A patent/HK1129566A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR20090024181A (ko) | 2009-03-06 |
EP2019669B1 (en) | 2011-11-23 |
HK1129566A1 (en) | 2009-12-04 |
CN101489538B (zh) | 2014-01-08 |
PE20080180A1 (es) | 2008-04-22 |
JP5162475B2 (ja) | 2013-03-13 |
CN103520158A (zh) | 2014-01-22 |
CA2653786A1 (en) | 2007-11-29 |
TWI407959B (zh) | 2013-09-11 |
MY146781A (en) | 2012-09-28 |
EP2019669A1 (en) | 2009-02-04 |
WO2007136129A1 (en) | 2007-11-29 |
JP2009538268A (ja) | 2009-11-05 |
CN101489538A (zh) | 2009-07-22 |
US20100136122A1 (en) | 2010-06-03 |
CA2653786C (en) | 2014-09-23 |
CL2007001457A1 (es) | 2008-01-04 |
US8865217B2 (en) | 2014-10-21 |
CN103520158B (zh) | 2016-02-03 |
ATE534374T1 (de) | 2011-12-15 |
ES2377839T3 (es) | 2012-04-02 |
TW200806332A (en) | 2008-02-01 |
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