AR060784A1 - Mezclas binarias de acido hialuronico y su uso terapeutico - Google Patents
Mezclas binarias de acido hialuronico y su uso terapeuticoInfo
- Publication number
- AR060784A1 AR060784A1 ARP070101970A ARP070101970A AR060784A1 AR 060784 A1 AR060784 A1 AR 060784A1 AR P070101970 A ARP070101970 A AR P070101970A AR P070101970 A ARP070101970 A AR P070101970A AR 060784 A1 AR060784 A1 AR 060784A1
- Authority
- AR
- Argentina
- Prior art keywords
- hyaluronic acid
- weight
- molecular weight
- samples
- sec
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Composiciones de ácido hialuronico que consisten en mezclas binarias de muestras de ácido hialuronico con diferente peso molecular promedio-peso y, por ende, diferentes propiedades reologicas en solucion acuosa. Las composiciones resultantes han demostrado una conducta reologica peculiar, con un equilibrio entre viscosidad y viscoelasticidad. Por lo tanto, estas composiciones de ácido hialuronico son utiles para el tratamiento de enfermedades articulares por administracion intra-articular o aplicacion extra-articular en trastornos de los tejidos blandos. Reivindicacion 1: Una mezcla binaria que comprende dos muestras de ácido hialuronico en forma de sal, en donde las características reologicas de dicha mezcla binaria, a una concentracion de 10 mg/ml en solucion acuosa y a una temperatura de 25°C, son: una viscosidad de flujo de un valor de al menos 5 Pa/seg a un índice de cizallamiento de 1 seg, una viscoelasticidad por reología dinámica con G' de al menos 7,5 Pa y G'' de al menos 7,0 Pa a 1 Hz, y en donde dichas dos muestras de ácido hialuronico tienen: a) la primera muestra un peso molecular promedio-peso inferior a 1.000.000 Da, b) la segunda muestra un peso molecular promedio-peso superior a 1.500.000 Da.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2006/062236 WO2007131546A1 (en) | 2006-05-11 | 2006-05-11 | Hyaluronic acid binary mixtures and therapeutic use thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR060784A1 true AR060784A1 (es) | 2008-07-10 |
Family
ID=37691747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070101970A AR060784A1 (es) | 2006-05-11 | 2007-05-07 | Mezclas binarias de acido hialuronico y su uso terapeutico |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20090163441A1 (es) |
| EP (1) | EP2026821B1 (es) |
| JP (1) | JP2009536625A (es) |
| CN (1) | CN101437527A (es) |
| AR (1) | AR060784A1 (es) |
| AT (1) | ATE440609T1 (es) |
| BR (1) | BRPI0621656B8 (es) |
| CA (1) | CA2651039C (es) |
| DE (1) | DE602006008834D1 (es) |
| EA (1) | EA014469B1 (es) |
| ES (1) | ES2332667T3 (es) |
| MX (1) | MX2008014403A (es) |
| MY (1) | MY149505A (es) |
| PL (1) | PL2026821T3 (es) |
| PT (1) | PT2026821E (es) |
| TW (1) | TWI399208B (es) |
| WO (1) | WO2007131546A1 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI516269B (zh) * | 2009-08-14 | 2016-01-11 | 禾伸堂生技股份有限公司 | 使用於炎症性腸疾病（ｉｂｄ）治療和預防之透明質酸混合物 |
| TWI383796B (zh) * | 2009-08-14 | 2013-02-01 | Holy Stone Healthcare Co Ltd | Use of hyaluronic acid mixture for the treatment and prevention of peptic ulcer and duodenal ulcer |
| IT1402382B1 (it) * | 2010-09-09 | 2013-09-04 | Ibsa Inst Biochimique Sa | Complessi cooperativi ibridi di acido ialuronico |
| US9636352B2 (en) * | 2011-03-16 | 2017-05-02 | The Charlotte-Mecklenburg Hospital Authority | Compositions and methods for the treatment of musculoskeletal related diseases and disorders using metal ion-citrate analog complexes |
| LT2543357T (lt) * | 2011-07-07 | 2018-06-11 | Holy Stone Healthcare Co.,Ltd. | Kompozicija, skirta panaudoti su uždegimu susijusių susirgimų gydymui arba prevencijai |
| ES2665254T3 (es) * | 2011-07-12 | 2018-04-25 | Holy Stone Healthcare Co., Ltd. | Composiciones que comprenden ácido hialurónico para tratamiento y prevención de enfermedades relacionadas con las mucosas |
| US10344243B2 (en) | 2012-10-19 | 2019-07-09 | Cornell University | Biomimetic boundary lubricants for articular cartilage |
| WO2017119198A1 (ja) * | 2016-01-05 | 2017-07-13 | デンカ株式会社 | 半月板変性治療用組成物 |
| KR20170090965A (ko) | 2016-01-29 | 2017-08-08 | 한미약품 주식회사 | 복합 히알루론산 가교물 및 그 제조방법 |
| WO2017131298A1 (en) * | 2016-01-29 | 2017-08-03 | Hanmi Pharm. Co., Ltd. | Combination of cross-linked hyaluronic acids and method of preparing the same |
| CN106109265B (zh) * | 2016-08-02 | 2018-08-21 | 华熙福瑞达生物医药有限公司 | 一种透明质酸保湿组合物及其制备方法和应用 |
| CN106137786B (zh) * | 2016-08-02 | 2018-09-18 | 华熙福瑞达生物医药有限公司 | 一种透明质酸抗衰组合物及其制备方法和应用 |
| IT201700008651A1 (it) * | 2017-01-26 | 2018-07-26 | Beauty System Pharma Ltd | Acido ialuronico reticolato con agenti reticolanti di tipo naturale o semisintetico |
| RU2644724C1 (ru) * | 2017-04-18 | 2018-02-13 | Георгий Сергеевич Немов | Средство, обладающее корректирующим действием на метаболизм хрящевой ткани и способ его получения |
| US20210033605A1 (en) * | 2018-04-03 | 2021-02-04 | Sanofi | Lateral flow immunoassay strip device |
| IT201900024214A1 (it) * | 2019-12-17 | 2021-06-17 | Altergon Sa | Sostituti del liquido sinoviale |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4303676A (en) * | 1980-03-21 | 1981-12-01 | Balazs Endre A | Hyaluronate based compositions and cosmetic formulations containing same |
| IT1212892B (it) * | 1983-10-11 | 1989-11-30 | Della Valle Francesco | Acido ialuronico ottenuto per mezzodi filtrazione molecolare sprovvisto di attivita' infiammatoria e sua utilizzazione terapeutica |
| JP3751017B2 (ja) * | 1992-02-10 | 2006-03-01 | アドバンスト メディカル オプティクス， インコーポレーテッド | 二頂分子量ヒアルロネート製剤およびその使用方法 |
| AU8136801A (en) * | 2000-07-31 | 2002-02-13 | Dermal Res Lab Inc | Methods of preventing or treating diseases and conditions using complex carbohydrates |
| FR2861734B1 (fr) * | 2003-04-10 | 2006-04-14 | Corneal Ind | Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus |
| AU2004277290B2 (en) * | 2003-10-09 | 2010-05-13 | Robert John Petrella | Methods for treating acute and overuse sprain and strain using hyaluronic acid |
-
2006
- 2006-05-11 ES ES06755148T patent/ES2332667T3/es active Active
- 2006-05-11 EP EP06755148A patent/EP2026821B1/en active Active
- 2006-05-11 AT AT06755148T patent/ATE440609T1/de active
- 2006-05-11 US US12/300,114 patent/US20090163441A1/en not_active Abandoned
- 2006-05-11 JP JP2009508146A patent/JP2009536625A/ja active Pending
- 2006-05-11 WO PCT/EP2006/062236 patent/WO2007131546A1/en active Application Filing
- 2006-05-11 EA EA200802307A patent/EA014469B1/ru unknown
- 2006-05-11 PT PT06755148T patent/PT2026821E/pt unknown
- 2006-05-11 CA CA2651039A patent/CA2651039C/en active Active
- 2006-05-11 PL PL06755148T patent/PL2026821T3/pl unknown
- 2006-05-11 CN CNA2006800545026A patent/CN101437527A/zh active Pending
- 2006-05-11 BR BRPI0621656A patent/BRPI0621656B8/pt active IP Right Grant
- 2006-05-11 DE DE602006008834T patent/DE602006008834D1/de active Active
- 2006-05-11 MX MX2008014403A patent/MX2008014403A/es active IP Right Grant
-
2007
- 2007-04-16 MY MYPI20070590A patent/MY149505A/en unknown
- 2007-05-07 AR ARP070101970A patent/AR060784A1/es not_active Application Discontinuation
- 2007-05-10 TW TW096116573A patent/TWI399208B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2026821A1 (en) | 2009-02-25 |
| PL2026821T3 (pl) | 2010-03-31 |
| MX2008014403A (es) | 2009-03-23 |
| BRPI0621656B8 (pt) | 2021-05-25 |
| EA014469B1 (ru) | 2010-12-30 |
| TWI399208B (zh) | 2013-06-21 |
| EA200802307A1 (ru) | 2009-04-28 |
| EP2026821B1 (en) | 2009-08-26 |
| BRPI0621656B1 (pt) | 2019-07-16 |
| DE602006008834D1 (de) | 2009-10-08 |
| TW200812597A (en) | 2008-03-16 |
| CA2651039A1 (en) | 2007-11-22 |
| PT2026821E (pt) | 2009-12-09 |
| JP2009536625A (ja) | 2009-10-15 |
| ES2332667T3 (es) | 2010-02-10 |
| US20090163441A1 (en) | 2009-06-25 |
| BRPI0621656A2 (pt) | 2011-12-20 |
| MY149505A (en) | 2013-09-13 |
| CN101437527A (zh) | 2009-05-20 |
| ATE440609T1 (de) | 2009-09-15 |
| WO2007131546A1 (en) | 2007-11-22 |
| CA2651039C (en) | 2013-12-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |