AR057545A1 - Procedimiento mejorado para la obtencion de acido betulinico - Google Patents

Procedimiento mejorado para la obtencion de acido betulinico

Info

Publication number
AR057545A1
AR057545A1 ARP060104454A ARP060104454A AR057545A1 AR 057545 A1 AR057545 A1 AR 057545A1 AR P060104454 A ARP060104454 A AR P060104454A AR P060104454 A ARP060104454 A AR P060104454A AR 057545 A1 AR057545 A1 AR 057545A1
Authority
AR
Argentina
Prior art keywords
improved procedure
obtaining
acid
betulin acid
xylene
Prior art date
Application number
ARP060104454A
Other languages
English (en)
Inventor
Carsten H Puder
Herbert Graef
Markus J Thumerer
Markus Heitzmann
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of AR057545A1 publication Critical patent/AR057545A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Extraction Or Liquid Replacement (AREA)

Abstract

Reivindicacion 1: Procedimiento mejorado para la obtencion de ácido betulínico muy puro mediante extraccion de corteza molida de plátano comun, caracterizado porque la extraccion se lleva a cabo con una mezcla de disolventes consistente en tolueno, xileno o tolueno/xileno y uno o varios alcoholes C1-6, o ésteres del ácido acético, o cetonas C3-6.
ARP060104454A 2005-10-12 2006-10-11 Procedimiento mejorado para la obtencion de acido betulinico AR057545A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05109482 2005-10-12

Publications (1)

Publication Number Publication Date
AR057545A1 true AR057545A1 (es) 2007-12-05

Family

ID=36046978

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP060104454A AR057545A1 (es) 2005-10-12 2006-10-11 Procedimiento mejorado para la obtencion de acido betulinico

Country Status (15)

Country Link
US (1) US20070149490A1 (es)
EP (1) EP1937707B1 (es)
JP (1) JP5203950B2 (es)
KR (1) KR20080059434A (es)
CN (1) CN101287745A (es)
AR (1) AR057545A1 (es)
AT (1) ATE493429T1 (es)
BR (1) BRPI0617226A2 (es)
CA (1) CA2624996A1 (es)
DE (1) DE502006008620D1 (es)
ES (1) ES2358752T3 (es)
IL (1) IL190743A0 (es)
RU (1) RU2008118419A (es)
TW (1) TW200720287A (es)
WO (1) WO2007042542A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102206244B (zh) * 2011-04-02 2012-07-04 南京林业大学 从梧桐树科树皮中提取桦木酸的方法
CN102527066B (zh) * 2012-02-23 2014-09-17 李晓云 多功能热回流提取浓缩机组
CN111333693B (zh) * 2020-04-22 2021-02-12 南京林业大学 一种桦木酸的提取方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19713768B4 (de) * 1997-04-03 2006-07-13 Martin-Luther-Universität Halle-Wittenberg Herstellung von Betulinsäure
US6048847A (en) * 1997-09-30 2000-04-11 Dabur Research Foundation Use of betulinic acid and its derivatives for inhibiting cancer growth and a method of monitoring this
US6264998B1 (en) * 2000-03-01 2001-07-24 Dabur Research Foundation Extracting betulinic acid from Ziziphus jujuba
EP1355708B1 (en) * 2000-09-29 2008-04-30 Regents Of The University Of Minnesota Process for extracting compounds from plants
US20020155177A1 (en) * 2000-09-29 2002-10-24 Krasutsky Pavel A. Process for extracting compounds from plants
WO2002091858A1 (en) * 2001-05-11 2002-11-21 University Of Ottawa Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods
DE10204271B4 (de) * 2002-02-02 2004-01-15 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Gewinnung von Betulinsäure-Monoethanolat
US6943260B2 (en) * 2002-02-02 2005-09-13 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for obtaining betulinic acid
CN1634972A (zh) * 2004-11-12 2005-07-06 张梅 白桦脂醇和白桦酯酸的提取纯化方法

Also Published As

Publication number Publication date
JP5203950B2 (ja) 2013-06-05
EP1937707A1 (de) 2008-07-02
ATE493429T1 (de) 2011-01-15
RU2008118419A (ru) 2009-11-20
CN101287745A (zh) 2008-10-15
US20070149490A1 (en) 2007-06-28
CA2624996A1 (en) 2007-04-19
IL190743A0 (en) 2009-09-22
ES2358752T3 (es) 2011-05-13
EP1937707B1 (de) 2010-12-29
WO2007042542A1 (de) 2007-04-19
TW200720287A (en) 2007-06-01
JP2009511546A (ja) 2009-03-19
BRPI0617226A2 (pt) 2011-07-19
DE502006008620D1 (de) 2011-02-10
KR20080059434A (ko) 2008-06-27

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