AR055090A1 - Una presentacion farmaceutica de forma de dosificacion de liberacion modificada que comprende un inhibidor de la enzima ciclooxigenasa - Google Patents
Una presentacion farmaceutica de forma de dosificacion de liberacion modificada que comprende un inhibidor de la enzima ciclooxigenasaInfo
- Publication number
- AR055090A1 AR055090A1 ARP060103141A ARP060103141A AR055090A1 AR 055090 A1 AR055090 A1 AR 055090A1 AR P060103141 A ARP060103141 A AR P060103141A AR P060103141 A ARP060103141 A AR P060103141A AR 055090 A1 AR055090 A1 AR 055090A1
- Authority
- AR
- Argentina
- Prior art keywords
- presentation
- cyclooxygenase
- inhibitor
- sodium lauryl
- lauryl sulfate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Se provee una presentacion farmacéutica de liberacion modificada que comprende al menos un inhibidor de la enzima ciclooxigenasa o sus sales, ésteres, profármacos, solvatos, hidratos o derivados farmacéuticamente aceptables como agente activo, con un portador farmacéuticamente aceptable para controlar la liberacion del inhibidor de enzima ciclooxigenasa. La presentacion provee preferentemente una liberacion de no más de aproximadamente 60% del inhibidor de enzima ciclooxigenasa en 1 hora y no menos de aproximadamente 75% del inhibidor de enzima ciclooxigenasa luego de 12 horas cuando se somete a ensayo segun el método de disolucion (1) aquí descrito, empleándose agua destilada con lauril sulfato de sodio al 2,0% como medio de disolucion, o segun el método de disolucion (2) aquí descrito, empleándose buffer de fosfato pH 7,0 con lauril sulfato de sodio al 2,0% como medio de disolucion, o segun el método de disolucion (3) aquí descrito, empleándose ácido clorhídrico 0,001 N con lauril sulfato de sodio al 1,0% como medio de disolucion. Adicionalmente, la composicion farmacéutica de la presente, cuando es sometida a ensayo en un grupo de humanos sanos, preferentemente alcanza una concentracion máxima promedio en plasma (Cmáx) luego de al menos 1 hora a partir de a administracion de la presentacion. También se provee un proceso de preparacion de tales composiciones y métodos profilácticos y/o terapéuticos de uso de tal presentacion.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN1899DE2005 | 2005-07-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR055090A1 true AR055090A1 (es) | 2007-08-08 |
Family
ID=37669241
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP060103141A AR055090A1 (es) | 2005-07-20 | 2006-07-20 | Una presentacion farmaceutica de forma de dosificacion de liberacion modificada que comprende un inhibidor de la enzima ciclooxigenasa |
Country Status (20)
Country | Link |
---|---|
US (1) | US20100204333A1 (es) |
EP (1) | EP1906933A2 (es) |
JP (1) | JP2009501785A (es) |
KR (1) | KR20080032209A (es) |
CN (1) | CN101227893A (es) |
AR (1) | AR055090A1 (es) |
AU (1) | AU2006271150A1 (es) |
BR (1) | BRPI0613547A2 (es) |
CA (1) | CA2614850A1 (es) |
CR (1) | CR9828A (es) |
DE (1) | DE202006020331U1 (es) |
DK (1) | DK200900115U1 (es) |
EA (1) | EA200800370A1 (es) |
MX (1) | MX2008000967A (es) |
NO (1) | NO20080697L (es) |
RS (1) | RS20080020A (es) |
TN (1) | TNSN08018A1 (es) |
UA (1) | UA89684C2 (es) |
WO (1) | WO2007010559A2 (es) |
ZA (1) | ZA200801592B (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101431992A (zh) * | 2006-04-24 | 2009-05-13 | 万能药生物有限公司 | 包含尼美舒利的新型低剂量药物组合物及其制备和用途 |
RU2463038C2 (ru) | 2006-10-17 | 2012-10-10 | Нуво Рисерч Инк. | Диклофенаковый гель |
US8546450B1 (en) * | 2009-03-31 | 2013-10-01 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
US8618164B2 (en) | 2009-03-31 | 2013-12-31 | Nuvo Research Inc. | Treatment of pain with topical diclofenac compounds |
EP2443094B1 (en) | 2009-06-19 | 2013-03-20 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of telmisartan |
CN102188386B (zh) * | 2010-03-02 | 2013-09-04 | 海南葫芦娃制药有限公司 | 尼美舒利缓释微丸及其制备方法 |
US8951996B2 (en) * | 2011-07-28 | 2015-02-10 | Lipocine Inc. | 17-hydroxyprogesterone ester-containing oral compositions and related methods |
WO2013103390A1 (en) * | 2012-01-04 | 2013-07-11 | Wellesley Pharmaceuticals, Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
US10632087B2 (en) | 2012-02-06 | 2020-04-28 | Innovative Med Concepts, LLC. | Famciclovir and meloxicam combination therapy for functional somatic syndromes |
US9018246B2 (en) | 2012-09-05 | 2015-04-28 | Lp Pharmaceutical (Xiamen) Co., Ltd. | Transmucosal administration of taxanes |
HUP1500618A2 (en) | 2015-12-16 | 2017-06-28 | Druggability Tech Ip Holdco Ltd | Complexes of celecoxib and its salts and derivatives, process for the preparation thereof and pharmaceutical composition containing them |
US10350171B2 (en) | 2017-07-06 | 2019-07-16 | Dexcel Ltd. | Celecoxib and amlodipine formulation and method of making the same |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE66933B1 (en) * | 1990-01-15 | 1996-02-07 | Elan Corp Plc | Controlled absorption naproxen formulation for once-daily administration |
US5478577A (en) | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
ES2129010B1 (es) * | 1997-01-02 | 2000-01-16 | Gold Oscar | Composicion de accion prolongada en granulos que contienen 4-nitro-2- fenoximetansulfonanilida y su procedimiento de preparacion. |
EP1017370B1 (en) | 1997-09-11 | 2003-10-29 | Nycomed Danmark ApS | MODIFIED RELEASE MULTIPLE-UNITS COMPOSITIONS OF NON-STEROID ANTI-INFLAMMATORY DRUG SUBSTANCES (NSAIDs) |
IN188720B (es) * | 1997-11-06 | 2002-11-02 | Panacea Biotec Ltd | |
AU718356B2 (en) * | 1998-01-12 | 2000-04-13 | Panacea Biotec Limited | A parenteral water-miscible non-intensely coloured injectable composition of non-steroidal anit-inflammatory drugs |
WO2000004879A1 (en) * | 1998-07-24 | 2000-02-03 | Andrix Pharmaceuticals, Inc. | Granule modulating hydrogel system |
US6086920A (en) | 1998-08-12 | 2000-07-11 | Fuisz Technologies Ltd. | Disintegratable microspheres |
PT1109534E (pt) | 1998-09-10 | 2003-06-30 | Nycomed Danmark As | Composicoes farmaceuticas de farmacos de libertacao rapida |
EP1218889B1 (en) * | 1999-09-28 | 2009-12-02 | Panacea Biotec Limited | Controlled release compositions comprising nimesulide |
IN190018B (es) * | 1999-09-28 | 2003-05-31 | Panacea Biotec Ltd | |
CA2394222A1 (en) | 1999-12-22 | 2001-06-28 | Pharmacia Corporation | Sustained-release formulation of a cyclooxygenase-2 inhibitor |
WO2001078725A2 (en) | 2000-04-13 | 2001-10-25 | Synthon B.V. | Modified release formulations containing a hypnotic agent |
IN190963B (es) * | 2000-06-20 | 2003-09-06 | Ajanta Pharma Ltd | |
CA2498798A1 (en) | 2002-09-20 | 2004-04-01 | Alpharma, Inc. | Sustained-release opioid formulations and methods of use |
DE602004007315D1 (de) * | 2003-03-03 | 2007-08-16 | Personnes A Responsibilite Lim | Stabilisierte pharmazeutische Zusammensetzung enthaltend einen NSAID und einen Prostaglandin |
US20050129764A1 (en) * | 2003-12-11 | 2005-06-16 | Vergez Juan A. | Osmotic device containing licofelone |
-
2006
- 2006-07-19 EA EA200800370A patent/EA200800370A1/ru unknown
- 2006-07-19 KR KR1020087004111A patent/KR20080032209A/ko not_active Application Discontinuation
- 2006-07-19 BR BRPI0613547-1A patent/BRPI0613547A2/pt not_active IP Right Cessation
- 2006-07-19 CN CNA2006800263960A patent/CN101227893A/zh active Pending
- 2006-07-19 UA UAA200802135A patent/UA89684C2/ru unknown
- 2006-07-19 EP EP06780539A patent/EP1906933A2/en not_active Withdrawn
- 2006-07-19 US US11/988,860 patent/US20100204333A1/en not_active Abandoned
- 2006-07-19 MX MX2008000967A patent/MX2008000967A/es not_active Application Discontinuation
- 2006-07-19 WO PCT/IN2006/000258 patent/WO2007010559A2/en active Search and Examination
- 2006-07-19 ZA ZA200801592A patent/ZA200801592B/xx unknown
- 2006-07-19 AU AU2006271150A patent/AU2006271150A1/en not_active Abandoned
- 2006-07-19 RS RSP-2008/0020A patent/RS20080020A/sr unknown
- 2006-07-19 DE DE202006020331U patent/DE202006020331U1/de not_active Expired - Lifetime
- 2006-07-19 JP JP2008522177A patent/JP2009501785A/ja not_active Abandoned
- 2006-07-19 CA CA002614850A patent/CA2614850A1/en not_active Abandoned
- 2006-07-20 AR ARP060103141A patent/AR055090A1/es not_active Application Discontinuation
-
2008
- 2008-01-17 TN TNP2008000018A patent/TNSN08018A1/en unknown
- 2008-02-07 NO NO20080697A patent/NO20080697L/no not_active Application Discontinuation
- 2008-03-26 CR CR9828A patent/CR9828A/es not_active Application Discontinuation
-
2009
- 2009-07-06 DK DK200900115U patent/DK200900115U1/da unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI0613547A2 (pt) | 2011-01-18 |
RS20080020A (en) | 2009-05-06 |
JP2009501785A (ja) | 2009-01-22 |
KR20080032209A (ko) | 2008-04-14 |
CR9828A (es) | 2008-07-31 |
TNSN08018A1 (en) | 2009-07-14 |
MX2008000967A (es) | 2008-03-26 |
AU2006271150A1 (en) | 2007-01-25 |
CA2614850A1 (en) | 2007-01-25 |
ZA200801592B (en) | 2009-10-28 |
UA89684C2 (ru) | 2010-02-25 |
WO2007010559A2 (en) | 2007-01-25 |
DK200900115U1 (en) | 2009-10-23 |
WO2007010559A3 (en) | 2007-09-20 |
EA200800370A1 (ru) | 2008-06-30 |
US20100204333A1 (en) | 2010-08-12 |
CN101227893A (zh) | 2008-07-23 |
NO20080697L (no) | 2008-04-18 |
EP1906933A2 (en) | 2008-04-09 |
DE202006020331U1 (de) | 2008-09-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |