AR049940A1 - Uso de compuestos peptidicos para tratar tremor esencial y otros sindromes de tremor - Google Patents
Uso de compuestos peptidicos para tratar tremor esencial y otros sindromes de tremorInfo
- Publication number
- AR049940A1 AR049940A1 ARP050102604A ARP050102604A AR049940A1 AR 049940 A1 AR049940 A1 AR 049940A1 AR P050102604 A ARP050102604 A AR P050102604A AR P050102604 A ARP050102604 A AR P050102604A AR 049940 A1 AR049940 A1 AR 049940A1
- Authority
- AR
- Argentina
- Prior art keywords
- azethyl
- lower alkyl
- heterocyclyl
- aryl
- group
- Prior art date
Links
- 206010044565 Tremor Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 201000006517 essential tremor Diseases 0.000 title 1
- 208000011580 syndromic disease Diseases 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 25
- 125000000623 heterocyclic group Chemical group 0.000 abstract 15
- 125000003118 aryl group Chemical group 0.000 abstract 12
- -1 methylpyrrolyl Chemical group 0.000 abstract 8
- 229910052739 hydrogen Inorganic materials 0.000 abstract 7
- 239000001257 hydrogen Substances 0.000 abstract 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
- 125000003342 alkenyl group Chemical group 0.000 abstract 6
- 125000000304 alkynyl group Chemical group 0.000 abstract 6
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 6
- 125000001475 halogen functional group Chemical group 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 2
- 125000001425 triazolyl group Chemical group 0.000 abstract 2
- 101100134927 Gallus gallus COR8 gene Proteins 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 125000004618 benzofuryl group Chemical group O1C(=CC2=C1C=CC=C2)* 0.000 abstract 1
- 125000004196 benzothienyl group Chemical group S1C(=CC2=C1C=CC=C2)* 0.000 abstract 1
- 125000004541 benzoxazolyl group Chemical group O1C(=NC2=C1C=CC=C2)* 0.000 abstract 1
- 125000003838 furazanyl group Chemical group 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000002636 imidazolinyl group Chemical group 0.000 abstract 1
- 125000002883 imidazolyl group Chemical group 0.000 abstract 1
- 125000003453 indazolyl group Chemical group N1N=C(C2=C1C=CC=C2)* 0.000 abstract 1
- 125000003387 indolinyl group Chemical group N1(CCC2=CC=CC=C12)* 0.000 abstract 1
- 125000001041 indolyl group Chemical group 0.000 abstract 1
- 125000005956 isoquinolyl group Chemical group 0.000 abstract 1
- 125000001786 isothiazolyl group Chemical group 0.000 abstract 1
- 125000000842 isoxazolyl group Chemical group 0.000 abstract 1
- 125000002757 morpholinyl group Chemical group 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- 125000005936 piperidyl group Chemical group 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 125000000561 purinyl group Chemical group N1=C(N=C2N=CNC2=C1)* 0.000 abstract 1
- 125000004309 pyranyl group Chemical group O1C(C=CC=C1)* 0.000 abstract 1
- 125000003373 pyrazinyl group Chemical group 0.000 abstract 1
- 125000003226 pyrazolyl group Chemical group 0.000 abstract 1
- 125000002098 pyridazinyl group Chemical group 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
- 125000001422 pyrrolinyl group Chemical group 0.000 abstract 1
- 125000000168 pyrrolyl group Chemical group 0.000 abstract 1
- 125000005493 quinolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 abstract 1
- 125000003831 tetrazolyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58208404P | 2004-06-24 | 2004-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR049940A1 true AR049940A1 (es) | 2006-09-13 |
Family
ID=34970895
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP050102604A AR049940A1 (es) | 2004-06-24 | 2005-06-24 | Uso de compuestos peptidicos para tratar tremor esencial y otros sindromes de tremor |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7427601B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1758606A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5038892B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20070034477A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1964733B (cg-RX-API-DMAC7.html) |
| AR (1) | AR049940A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2005256468B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0512622A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2566301C (cg-RX-API-DMAC7.html) |
| EA (1) | EA013592B1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL179732A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA06015010A (cg-RX-API-DMAC7.html) |
| MY (1) | MY146509A (cg-RX-API-DMAC7.html) |
| NO (1) | NO20070423L (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ551207A (cg-RX-API-DMAC7.html) |
| TW (1) | TWI361693B (cg-RX-API-DMAC7.html) |
| UA (1) | UA88166C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006000397A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200609021B (cg-RX-API-DMAC7.html) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60120104T2 (de) * | 2001-03-20 | 2006-09-21 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen bei der Behandlung von nicht-neuropathischem Entzündungsschmerz |
| PT1243263E (pt) * | 2001-03-21 | 2003-03-31 | Sanol Arznei Schwarz Gmbh | Nova utilizacao de uma classe peptidica de composto para o tratamento de alodinia ou de outros tipos diferentes de dor cronica ou fantasma |
| ATE428413T1 (de) * | 2003-12-02 | 2009-05-15 | Sanol Arznei Schwarz Gmbh | Neue verwendung von peptidverbindungen zur behandlung ovn zentralen neuropathischen schmerzen |
| US20070042969A1 (en) * | 2004-03-26 | 2007-02-22 | Srz Properties, Inc. | Combination therapy for pain in painful diabetic neuropathy |
| US20100256179A1 (en) * | 2004-03-26 | 2010-10-07 | Ucb Pharma Gmbh | Combination therapy for pain in painful diabetic neuropathy |
| EP1579858A1 (en) * | 2004-03-26 | 2005-09-28 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in painful diabetic neuropathy |
| CA2562937A1 (en) * | 2004-04-16 | 2005-10-27 | Schwarz Pharma Ag | Use of peptidic compounds for the prophylaxis and treatment of chronic headache |
| EP1604655A1 (en) * | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating pain in trigeminal neuralgia |
| NZ552651A (en) * | 2004-08-27 | 2010-07-30 | Sanol Arznei Schwarz Gmbh | Novel use of peptide compounds for treating bone cancer pain, chemotherapy-and nucleoside-induced pain |
| EP1642889A1 (en) * | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
| US20060252749A1 (en) * | 2005-01-28 | 2006-11-09 | Srz Properties, Inc. | Lacosamide for add-on therapy of psychosis |
| EP1754476A1 (en) * | 2005-08-18 | 2007-02-21 | Schwarz Pharma Ag | Lacosamide (SPM 927) for treating myalgia, e.g. fibromyalgia |
| US20070043120A1 (en) * | 2005-08-18 | 2007-02-22 | Bettina Beyreuther | Therapeutic combination for painful medical conditions |
| US20070048372A1 (en) * | 2005-08-18 | 2007-03-01 | Srz Properties, Inc. | Method for treating non-inflammatory osteoarthritic pain |
| US7902401B2 (en) * | 2006-12-14 | 2011-03-08 | Nps Pharmaceuticals, Inc. | Fluorinated compounds |
| TWI397417B (zh) | 2006-06-15 | 2013-06-01 | Ucb Pharma Gmbh | 具有協同抗驚厥功效之醫藥組成物 |
| CN101466390B (zh) * | 2006-06-15 | 2014-03-12 | 优时比制药有限公司 | 用于治疗难治性癫痫持续状态的肽类化合物 |
| US8450336B2 (en) * | 2006-12-14 | 2013-05-28 | Nps Pharmaceuticals, Inc | Use of D-serine derivatives for the treatment of anxiety disorders |
| US7747551B2 (en) * | 2007-02-21 | 2010-06-29 | Neurovista Corporation | Reduction of classification error rates and monitoring system using an artificial class |
| WO2011037833A2 (en) | 2009-09-23 | 2011-03-31 | The University Of North Carolina At Chapel Hill | Novel n-benzylamide substituted derivatives of 2-(acylamido)acetic acid and 2-(acylamido)propionic acids: potent neurological agents |
| US20110281808A1 (en) * | 2010-05-14 | 2011-11-17 | Allmax Nutrition Inc. | Composition and Method for Increasing Pre Workout Thermogenics |
| JP6027539B2 (ja) | 2010-12-02 | 2016-11-16 | ウーツェーベー ファルマ ゲーエムベーハーＵｃｂ Ｐｈａｒｍａ Ｇｍｂｈ | ラコサミドの１日１回投与用製剤 |
| EP2468261A1 (en) | 2010-12-02 | 2012-06-27 | UCB Pharma GmbH | Formulation of lacosamide |
| KR20230050474A (ko) * | 2016-08-11 | 2023-04-14 | 오비드 테라퓨틱스 인크. | 간질 장애의 치료를 위한 방법 및 조성물 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5378729A (en) | 1985-02-15 | 1995-01-03 | Research Corporation Technologies, Inc. | Amino acid derivative anticonvulsant |
| US5773475A (en) * | 1997-03-17 | 1998-06-30 | Research Corporation Technologies, Inc. | Anticonvulsant enantiomeric amino acid derivatives |
| US6277825B1 (en) | 1996-07-22 | 2001-08-21 | University Of Utah Research Foundation | Use of conantokins for treating pain |
| US6589994B1 (en) | 1996-08-30 | 2003-07-08 | Nps Pharmaceuticals, Inc. | Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound |
| US5866585A (en) * | 1997-05-22 | 1999-02-02 | Synchroneuron, Llc | Methods of treating tardive dyskinesia using NMDA receptor antagonists |
| US6197764B1 (en) | 1997-11-26 | 2001-03-06 | Protarga, Inc. | Clozapine compositions and uses thereof |
| GB0004297D0 (en) * | 2000-02-23 | 2000-04-12 | Ucb Sa | 2-oxo-1 pyrrolidine derivatives process for preparing them and their uses |
| CA2418455A1 (en) * | 2000-08-17 | 2002-02-21 | Teva Pharmaceutical Industries, Ltd. | Valproic acid derivatives for the treatment of pain |
| DE10041478A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| ES2348646T3 (es) | 2000-08-25 | 2010-12-10 | Research Corporation Technologies, Inc. | Aminoacidos anticonvulsionantes para el tratamiento de la neurosis obsesivo-compulsiva. |
| ATE397584T1 (de) | 2000-11-21 | 2008-06-15 | Ucb Pharma Sa | N-alkylierte gaba verbindungen, verfahren zu deren herstellung und deren verwendung als arzneimittel |
| CA2438930A1 (en) * | 2001-02-23 | 2002-09-06 | Johns Hopkins University | Treatment of tics, tremors and related disorders |
| DE60120104T2 (de) | 2001-03-20 | 2006-09-21 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen bei der Behandlung von nicht-neuropathischem Entzündungsschmerz |
| PT1243263E (pt) | 2001-03-21 | 2003-03-31 | Sanol Arznei Schwarz Gmbh | Nova utilizacao de uma classe peptidica de composto para o tratamento de alodinia ou de outros tipos diferentes de dor cronica ou fantasma |
| TWI312285B (en) * | 2001-10-25 | 2009-07-21 | Depomed Inc | Methods of treatment using a gastric retained gabapentin dosage |
| US6828462B2 (en) * | 2001-11-07 | 2004-12-07 | Merz Pharma Gmbh & Co. Kgaa | Unsaturated 1-amino-alkylcyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists |
| US6559293B1 (en) * | 2002-02-15 | 2003-05-06 | Transform Pharmaceuticals, Inc. | Topiramate sodium trihydrate |
| WO2004024096A2 (en) * | 2002-09-13 | 2004-03-25 | Eisai Co., Ltd. | Method of treating tremors |
| ATE384078T1 (de) | 2002-11-18 | 2008-02-15 | Bioprospecting Nb Inc | Paralytisches peptide von der spitzmaus sowie dessen nutzung in der therapie von neuromuskulären krankheiten |
| US20050227961A1 (en) | 2004-04-08 | 2005-10-13 | Vela Pharmaceuticals, Inc. | Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome |
| EP1604654A1 (en) | 2004-05-18 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating dyskinesia |
| EP1604656A1 (en) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Novel use of peptide compounds for treating amyotrophic lateral sclerosis (ALS) |
-
2005
- 2005-06-10 US US11/149,181 patent/US7427601B2/en not_active Expired - Fee Related
- 2005-06-22 EA EA200700108A patent/EA013592B1/ru not_active IP Right Cessation
- 2005-06-22 CN CN2005800185331A patent/CN1964733B/zh not_active Expired - Fee Related
- 2005-06-22 CA CA2566301A patent/CA2566301C/en not_active Expired - Fee Related
- 2005-06-22 NZ NZ551207A patent/NZ551207A/en not_active IP Right Cessation
- 2005-06-22 JP JP2007517196A patent/JP5038892B2/ja not_active Expired - Fee Related
- 2005-06-22 AU AU2005256468A patent/AU2005256468B2/en not_active Ceased
- 2005-06-22 UA UAA200613472A patent/UA88166C2/ru unknown
- 2005-06-22 MX MXPA06015010A patent/MXPA06015010A/es active IP Right Grant
- 2005-06-22 WO PCT/EP2005/006750 patent/WO2006000397A1/en not_active Ceased
- 2005-06-22 KR KR1020067025264A patent/KR20070034477A/ko not_active Abandoned
- 2005-06-22 BR BRPI0512622-3A patent/BRPI0512622A/pt not_active IP Right Cessation
- 2005-06-22 EP EP05753740A patent/EP1758606A1/en not_active Withdrawn
- 2005-06-23 TW TW094121028A patent/TWI361693B/zh not_active IP Right Cessation
- 2005-06-24 MY MYPI20052909A patent/MY146509A/en unknown
- 2005-06-24 AR ARP050102604A patent/AR049940A1/es not_active Application Discontinuation
-
2006
- 2006-10-30 ZA ZA200609021A patent/ZA200609021B/xx unknown
- 2006-11-30 IL IL179732A patent/IL179732A0/en unknown
-
2007
- 2007-01-23 NO NO20070423A patent/NO20070423L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US7427601B2 (en) | 2008-09-23 |
| JP2008503533A (ja) | 2008-02-07 |
| EP1758606A1 (en) | 2007-03-07 |
| EA013592B1 (ru) | 2010-06-30 |
| AU2005256468A1 (en) | 2006-01-05 |
| UA88166C2 (ru) | 2009-09-25 |
| AU2005256468B2 (en) | 2010-12-09 |
| MXPA06015010A (es) | 2007-03-26 |
| NO20070423L (no) | 2007-03-22 |
| TW200603823A (en) | 2006-02-01 |
| CN1964733B (zh) | 2012-05-23 |
| CA2566301A1 (en) | 2006-01-05 |
| US20050288234A1 (en) | 2005-12-29 |
| TWI361693B (en) | 2012-04-11 |
| CA2566301C (en) | 2011-06-14 |
| BRPI0512622A (pt) | 2008-03-25 |
| JP5038892B2 (ja) | 2012-10-03 |
| IL179732A0 (en) | 2007-05-15 |
| MY146509A (en) | 2012-08-15 |
| NZ551207A (en) | 2010-07-30 |
| ZA200609021B (en) | 2008-04-30 |
| CN1964733A (zh) | 2007-05-16 |
| EA200700108A1 (ru) | 2007-06-29 |
| WO2006000397A1 (en) | 2006-01-05 |
| KR20070034477A (ko) | 2007-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |