AR046927A1 - Derivados de morfolina como inhibidores de la recaptacion de norepinefrina - Google Patents
Derivados de morfolina como inhibidores de la recaptacion de norepinefrinaInfo
- Publication number
- AR046927A1 AR046927A1 ARP040104126A ARP040104126A AR046927A1 AR 046927 A1 AR046927 A1 AR 046927A1 AR P040104126 A ARP040104126 A AR P040104126A AR P040104126 A ARP040104126 A AR P040104126A AR 046927 A1 AR046927 A1 AR 046927A1
- Authority
- AR
- Argentina
- Prior art keywords
- optionally substituted
- alkyl
- halogen atoms
- alkoxy
- hydroxy
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Child & Adolescent Psychology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Compuestos, métodos de preparacion, intermediarios, composiciones farmacéuticas, usos para el tratamiento de trastornos del sistema nervioso central y/o periférico, y procedimiento para inhibir la recaptacion de norepinefrina en mamíferos. Reivindicacion 1: Un compuesto de formula (1), en la que: X es OH, alcoxi C1-4, NH2 o NH(alquilo C1-4); Rx es H o alquilo C1-4; Ry es H o alquilo C1-4; cada grupo Rz es independientemente H o alquilo C1-4, con la condicion de que no más de 3 grupos Rz pueden ser alquilo C1-4; R1 es alquilo C1-6 (opcionalmente sustituido con 1, 2 o 3 átomos de halogeno y/o con 1 sustituyente seleccionado entre alquiltio C1-4 (opcionalmente sustituido con 1, 2 o 3 átomos de fluor), alcoxi C1-4 (opcionalmente sustituido con 1, 2 o 3 átomos de fluor), cicloalcoxi C3-6, alquilsulfonilo C1-4, ciano, -CO-O(alquilo C1-2), -O-CO-(alquil C1-2) e hidroxi); alquenilo C2-6 (opcionalmente sustituido con 1, 2 o 3 átomos de halogeno); cicloalquilo C3-6 (opcionalmente sustituido con 1, 2 o 3 átomos de halogeno y/o con 1 sustituyentes seleccionado entre alcoxi C1-4 e hidroxi) donde un enlace C-C del resto cicloalquilo está opcionalmente sustituido por un enlace O-C, S-C o C=C; cicloalquilalquilo C4- 7 (opcionalmente sustituido con 1, 2 o 3 átomos de halogeno y/o con 1 sustituyente seleccionado entre alcoxi C1-4 e hidroxi) donde un enlace C-C dentro del resto cicloalquilo está opcionalmente sustituido por un enlace O-C, S-C o C=C; o CH2Ar2; y cada uno de Ar1 y Ar2 es independientemente un anillo fenilo o un anillo heteroarilo de 5 o 6 miembros cada uno de los cuales está opcionalmente sustituido con 1, 2 o 3 sustituyentes (dependiendo del numero de posiciones de sustitucion disponibles) seleccionados independientemente, cada uno, entre alquilo C1-4 (opcionalmente sustituido con 1, 2 o 3 átomos de halogeno), alcoxi C1-4 (opcionalmente sustituido con 1, 2 o 3 átomos de halogeno), alquiltio C1-4 (opcionalmente sustituido con 1, 2 o 3 átomos de halogeno), -CO-O(alquilo C1-4), ciano, -NRR, -CONRR, halo e hidroxi y/o con 1 sustituyente seleccionado entre piridilo, tiofenilo, fenilo, bencilo y fenoxi, cada uno de los cuales está opcionalmente sustituido en el anillo con 1, 2 o 3 sustituyentes seleccionados independientemente cada uno entre halogeno, alquilo C1-4 (opcionalmente sustituido con 1, 2 o 3 átomos de halogeno), alcoxi C1-4 (opcionalmente sustituido con 1, 2 o 3 átomos de halogeno), carboxi, nitro, hidroxi, ciano, - NRR, -CONRR, SO2NRR y SO2R; y cada R es independientemente H o alquilo C1-4; o una sal farmacéuticamente aceptable del mismo.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0326148.4A GB0326148D0 (en) | 2003-11-10 | 2003-11-10 | Morpholine derivatives |
US53545904P | 2004-01-09 | 2004-01-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR046927A1 true AR046927A1 (es) | 2006-01-04 |
Family
ID=29726235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP040104126A AR046927A1 (es) | 2003-11-10 | 2004-11-09 | Derivados de morfolina como inhibidores de la recaptacion de norepinefrina |
Country Status (34)
Country | Link |
---|---|
US (1) | US7423037B2 (es) |
EP (2) | EP2223916A1 (es) |
JP (1) | JP4850068B2 (es) |
KR (1) | KR100783855B1 (es) |
CN (1) | CN1878762B (es) |
AR (1) | AR046927A1 (es) |
AT (1) | ATE478057T1 (es) |
AU (1) | AU2004289616B2 (es) |
BR (1) | BRPI0415273B8 (es) |
CA (1) | CA2544649C (es) |
CR (1) | CR8390A (es) |
CY (1) | CY1110796T1 (es) |
DE (1) | DE602004028750D1 (es) |
DK (1) | DK1682523T3 (es) |
EA (1) | EA009960B1 (es) |
EC (1) | ECSP066555A (es) |
ES (1) | ES2348872T3 (es) |
GB (1) | GB0326148D0 (es) |
HK (1) | HK1095135A1 (es) |
HR (1) | HRP20100476T1 (es) |
IL (1) | IL175365A (es) |
MA (1) | MA28330A1 (es) |
MY (1) | MY141048A (es) |
NO (1) | NO336268B1 (es) |
NZ (1) | NZ546067A (es) |
PE (1) | PE20050491A1 (es) |
PL (1) | PL1682523T3 (es) |
PT (1) | PT1682523E (es) |
SI (1) | SI1682523T1 (es) |
SV (1) | SV2006001934A (es) |
TW (1) | TWI339658B (es) |
UA (1) | UA85198C2 (es) |
WO (1) | WO2005047272A1 (es) |
ZA (1) | ZA200603680B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070015786A1 (en) * | 2003-12-12 | 2007-01-18 | Eli Lily And Company | Treatment of hot flashes, impulse control disorders and personality change due to a general medical condition |
US8580776B2 (en) * | 2007-07-10 | 2013-11-12 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating neurodegenerating diseases |
RU2613633C1 (ru) * | 2016-03-09 | 2017-03-21 | федеральное государственное бюджетное образовательное учреждение высшего образования "Санкт-Петербургская государственная химико-фармацевтическая академия" Министерства здравоохранения Российской Федерации (ФГБОУ ВО СПХФА Минздрава России) | Хлорид 4-[(1Е)-1-(6-хлор-4-оксо-4Н-хромен-3-ил)-4-метилпент-1-ен-3-ил]морфолин-4-ия, способ его получения и противотуберкулезная активность |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2645640A (en) | 1953-07-14 | Phenthiazine derivatives | ||
NL108827C (es) | 1956-04-09 | |||
GB895309A (en) | 1959-11-18 | 1962-05-02 | Res Lab Dr C Janssen Nv | Pyrrolidine and piperidine derivatives |
US3141823A (en) | 1962-09-04 | 1964-07-21 | Res Lab Dr C Janssen N V | Method for producing analgesia |
US3539573A (en) | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
JPS54130587A (en) | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
US4804663A (en) | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
IE58370B1 (en) | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
GB8607684D0 (en) | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
US4831031A (en) | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
US5006528A (en) | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
GB8908085D0 (en) | 1989-04-11 | 1989-05-24 | Lundbeck & Co As H | New therapeutic use |
US5238945A (en) | 1989-04-11 | 1993-08-24 | H. Lundbeck A/S | Method of treating psychoses |
US5229382A (en) | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
US5312925A (en) | 1992-09-01 | 1994-05-17 | Pfizer Inc. | Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride |
EG23659A (en) | 1995-03-24 | 2007-03-26 | Lilly Co Eli | Process and crystal forms of methyl-thieno-benzodiazepine |
AU9214498A (en) | 1997-09-23 | 1999-04-12 | Eli Lilly And Company | Treatment of attention-deficit/hyperactivity disorder |
CN1255389C (zh) | 1998-01-21 | 2006-05-10 | 葛兰素集团有限公司 | 医药活性的吗啉醇 |
WO2001000214A1 (en) * | 1999-06-30 | 2001-01-04 | Merck & Co., Inc. | Src kinase inhibitor compounds |
PT1459750E (pt) | 1999-07-01 | 2005-08-31 | Pharmacia & Upjohn Co Llc | (s,s)- reboxetina para tratar a fibromialgia ou outras perturbacoes somatoformes |
GB0120461D0 (en) * | 2001-08-22 | 2001-10-17 | Astrazeneca Ab | Novel compounds |
GB0219687D0 (en) * | 2002-08-23 | 2002-10-02 | Lilly Co Eli | Benzyl morpholine derivatives |
JP2004277318A (ja) * | 2003-03-14 | 2004-10-07 | Dainippon Pharmaceut Co Ltd | 1−(1−置換カルボニル−4−ピペリジニルメチル)ピペリジン誘導体およびそれを含有する医薬組成物 |
FR2852954B1 (fr) * | 2003-03-28 | 2006-07-14 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
-
2003
- 2003-11-10 GB GBGB0326148.4A patent/GB0326148D0/en not_active Ceased
-
2004
- 2004-10-22 TW TW093132096A patent/TWI339658B/zh active
- 2004-10-28 SI SI200431540T patent/SI1682523T1/sl unknown
- 2004-10-28 NZ NZ546067A patent/NZ546067A/en unknown
- 2004-10-28 AU AU2004289616A patent/AU2004289616B2/en active Active
- 2004-10-28 WO PCT/US2004/032771 patent/WO2005047272A1/en active Application Filing
- 2004-10-28 JP JP2006539492A patent/JP4850068B2/ja active Active
- 2004-10-28 AT AT04794209T patent/ATE478057T1/de active
- 2004-10-28 UA UAA200604519A patent/UA85198C2/ru unknown
- 2004-10-28 DE DE602004028750T patent/DE602004028750D1/de active Active
- 2004-10-28 PL PL04794209T patent/PL1682523T3/pl unknown
- 2004-10-28 CN CN2004800331155A patent/CN1878762B/zh active Active
- 2004-10-28 PT PT04794209T patent/PT1682523E/pt unknown
- 2004-10-28 EA EA200600945A patent/EA009960B1/ru unknown
- 2004-10-28 US US10/577,841 patent/US7423037B2/en active Active
- 2004-10-28 KR KR1020067008999A patent/KR100783855B1/ko active IP Right Grant
- 2004-10-28 EP EP10162865A patent/EP2223916A1/en not_active Withdrawn
- 2004-10-28 BR BRPI0415273A patent/BRPI0415273B8/pt active IP Right Grant
- 2004-10-28 EP EP04794209A patent/EP1682523B1/en active Active
- 2004-10-28 ES ES04794209T patent/ES2348872T3/es active Active
- 2004-10-28 CA CA2544649A patent/CA2544649C/en active Active
- 2004-10-28 DK DK04794209.9T patent/DK1682523T3/da active
- 2004-11-08 MY MYPI20044640A patent/MY141048A/en unknown
- 2004-11-09 AR ARP040104126A patent/AR046927A1/es active IP Right Grant
- 2004-11-09 PE PE2004001093A patent/PE20050491A1/es active IP Right Grant
- 2004-11-10 SV SV2004001934A patent/SV2006001934A/es unknown
-
2006
- 2006-05-01 IL IL175365A patent/IL175365A/en active IP Right Grant
- 2006-05-09 ZA ZA200603680A patent/ZA200603680B/en unknown
- 2006-05-09 EC EC2006006555A patent/ECSP066555A/es unknown
- 2006-05-10 CR CR8390A patent/CR8390A/es unknown
- 2006-06-02 MA MA29074A patent/MA28330A1/fr unknown
- 2006-06-12 NO NO20062700A patent/NO336268B1/no unknown
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2007
- 2007-01-05 HK HK07100215.2A patent/HK1095135A1/xx unknown
-
2010
- 2010-08-31 HR HR20100476T patent/HRP20100476T1/hr unknown
- 2010-09-23 CY CY20101100858T patent/CY1110796T1/el unknown
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