AR045693A1 - Derivados de monosacaridos de avermectina b1 - Google Patents
Derivados de monosacaridos de avermectina b1Info
- Publication number
- AR045693A1 AR045693A1 ARP040102059A ARP040102059A AR045693A1 AR 045693 A1 AR045693 A1 AR 045693A1 AR P040102059 A ARP040102059 A AR P040102059A AR P040102059 A ARP040102059 A AR P040102059A AR 045693 A1 AR045693 A1 AR 045693A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- alkoxy
- substituted
- aryl
- phenyl
- Prior art date
Links
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 25
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 15
- 125000003118 aryl group Chemical group 0.000 abstract 12
- 229910052736 halogen Inorganic materials 0.000 abstract 9
- 150000002367 halogens Chemical class 0.000 abstract 9
- 125000001424 substituent group Chemical group 0.000 abstract 9
- 125000004104 aryloxy group Chemical group 0.000 abstract 8
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 7
- 125000000623 heterocyclic group Chemical group 0.000 abstract 7
- 125000004642 (C1-C12) alkoxy group Chemical group 0.000 abstract 6
- 125000004641 (C1-C12) haloalkyl group Chemical group 0.000 abstract 6
- 125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 6
- 125000004648 C2-C8 alkenyl group Chemical group 0.000 abstract 6
- 125000004649 C2-C8 alkynyl group Chemical group 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 6
- 125000004209 (C1-C8) alkyl group Chemical group 0.000 abstract 5
- 125000003342 alkenyl group Chemical group 0.000 abstract 5
- 125000003545 alkoxy group Chemical group 0.000 abstract 5
- 125000004644 alkyl sulfinyl group Chemical group 0.000 abstract 5
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 5
- 125000004414 alkyl thio group Chemical group 0.000 abstract 5
- 125000005133 alkynyloxy group Chemical group 0.000 abstract 5
- 125000005844 heterocyclyloxy group Chemical group 0.000 abstract 5
- -1 methylenedioxy Chemical group 0.000 abstract 5
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 4
- 125000004643 (C1-C12) haloalkoxy group Chemical group 0.000 abstract 3
- 125000000304 alkynyl group Chemical group 0.000 abstract 3
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 3
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 3
- 125000004995 haloalkylthio group Chemical group 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 238000006467 substitution reaction Methods 0.000 abstract 3
- 125000006652 (C3-C12) cycloalkyl group Chemical group 0.000 abstract 2
- 125000004450 alkenylene group Chemical group 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000005149 cycloalkylsulfinyl group Chemical group 0.000 abstract 2
- 125000005144 cycloalkylsulfonyl group Chemical group 0.000 abstract 2
- 125000001072 heteroaryl group Chemical group 0.000 abstract 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- 125000004738 (C1-C6) alkyl sulfinyl group Chemical group 0.000 abstract 1
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 1
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 1
- 125000004737 (C1-C6) haloalkoxy group Chemical group 0.000 abstract 1
- 125000000171 (C1-C6) haloalkyl group Chemical group 0.000 abstract 1
- 125000004749 (C1-C6) haloalkylsulfinyl group Chemical group 0.000 abstract 1
- 125000004741 (C1-C6) haloalkylsulfonyl group Chemical group 0.000 abstract 1
- 125000003601 C2-C6 alkynyl group Chemical group 0.000 abstract 1
- 241000607479 Yersinia pestis Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005366 cycloalkylthio group Chemical group 0.000 abstract 1
- 125000000262 haloalkenyl group Chemical group 0.000 abstract 1
- 125000005291 haloalkenyloxy group Chemical group 0.000 abstract 1
- 125000004440 haloalkylsulfinyl group Chemical group 0.000 abstract 1
- 125000004441 haloalkylsulfonyl group Chemical group 0.000 abstract 1
- 125000005347 halocycloalkyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000003518 norbornenyl group Chemical group C12(C=CC(CC1)C2)* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000000575 pesticide Substances 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0313937.5A GB0313937D0 (en) | 2003-06-16 | 2003-06-16 | Avermectin B1 monosaccharide derivatives having an aminosulfonyloxy substituentin the 4'-position |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR045693A1 true AR045693A1 (es) | 2005-11-09 |
Family
ID=27636648
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP040102059A AR045693A1 (es) | 2003-06-16 | 2004-06-14 | Derivados de monosacaridos de avermectina b1 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US7521429B2 (enExample) |
| EP (1) | EP1638984B1 (enExample) |
| JP (1) | JP4750698B2 (enExample) |
| AR (1) | AR045693A1 (enExample) |
| AT (1) | ATE370157T1 (enExample) |
| CY (1) | CY1106940T1 (enExample) |
| DE (1) | DE602004008281T2 (enExample) |
| DK (1) | DK1638984T3 (enExample) |
| ES (1) | ES2293276T3 (enExample) |
| GB (1) | GB0313937D0 (enExample) |
| PL (1) | PL1638984T3 (enExample) |
| PT (1) | PT1638984E (enExample) |
| SI (1) | SI1638984T1 (enExample) |
| TW (1) | TW200504088A (enExample) |
| WO (1) | WO2004111070A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200538461A (en) * | 2004-04-07 | 2005-12-01 | Syngenta Participations Ag | Avermectin and avermectin monosaccharide substituted in the 4"-and 4'-position respectively |
| US20110281920A1 (en) | 2010-05-12 | 2011-11-17 | Robert Holmes | Injectable parasiticidal formulations of levamisole and macrocyclic lactones |
| WO2012078605A1 (en) | 2010-12-07 | 2012-06-14 | Merial Limited | Topical combination formulations of macrocyclic lactones with synthetic pyrethroids |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4622313A (en) * | 1985-08-01 | 1986-11-11 | Merck & Co., Inc. | O-sulfate derivatives of avermectins and milbemycins having improved water solubility |
| US4833168A (en) * | 1986-10-03 | 1989-05-23 | Merck & Co., Inc. | Avermectin reformatsky adducts |
| US4906619A (en) * | 1988-07-22 | 1990-03-06 | Merck & Co., Inc. | Alkyl avermectin derivatives |
| NZ231773A (en) * | 1988-12-23 | 1992-09-25 | Merck & Co Inc | Avermectin derivatives, preparation and parasiticidal pharmaceutical compositions thereof |
| US5208222A (en) | 1991-03-28 | 1993-05-04 | Merck & Co., Inc. | 4"-and 4'-alkylthio avermectin derivatives |
| GB9205007D0 (en) * | 1992-03-07 | 1992-04-22 | Pfizer Ltd | Antiparasitic agents |
| AR037938A1 (es) | 2001-12-21 | 2004-12-22 | Syngenta Participations Ag | Derivados de avermectina b1 que tienen un substituyente de aminosulfoniloxilo en la posicion 4'' |
-
2003
- 2003-06-16 GB GBGB0313937.5A patent/GB0313937D0/en not_active Ceased
-
2004
- 2004-06-14 AR ARP040102059A patent/AR045693A1/es unknown
- 2004-06-14 TW TW093117009A patent/TW200504088A/zh unknown
- 2004-06-15 US US10/560,390 patent/US7521429B2/en not_active Expired - Lifetime
- 2004-06-15 DK DK04739912T patent/DK1638984T3/da active
- 2004-06-15 PT PT04739912T patent/PT1638984E/pt unknown
- 2004-06-15 JP JP2006515942A patent/JP4750698B2/ja not_active Expired - Fee Related
- 2004-06-15 AT AT04739912T patent/ATE370157T1/de active
- 2004-06-15 PL PL04739912T patent/PL1638984T3/pl unknown
- 2004-06-15 WO PCT/EP2004/006442 patent/WO2004111070A1/en not_active Ceased
- 2004-06-15 DE DE602004008281T patent/DE602004008281T2/de not_active Expired - Lifetime
- 2004-06-15 SI SI200430477T patent/SI1638984T1/sl unknown
- 2004-06-15 ES ES04739912T patent/ES2293276T3/es not_active Expired - Lifetime
- 2004-06-15 EP EP04739912A patent/EP1638984B1/en not_active Expired - Lifetime
-
2007
- 2007-10-19 CY CY20071101344T patent/CY1106940T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SI1638984T1 (sl) | 2007-12-31 |
| GB0313937D0 (en) | 2003-07-23 |
| DE602004008281T2 (de) | 2008-05-15 |
| TW200504088A (en) | 2005-02-01 |
| EP1638984B1 (en) | 2007-08-15 |
| US20060229263A1 (en) | 2006-10-12 |
| CY1106940T1 (el) | 2012-09-26 |
| JP4750698B2 (ja) | 2011-08-17 |
| US7521429B2 (en) | 2009-04-21 |
| PL1638984T3 (pl) | 2008-02-29 |
| DK1638984T3 (da) | 2007-12-03 |
| PT1638984E (pt) | 2007-11-09 |
| WO2004111070A1 (en) | 2004-12-23 |
| DE602004008281D1 (en) | 2007-09-27 |
| EP1638984A1 (en) | 2006-03-29 |
| ATE370157T1 (de) | 2007-09-15 |
| JP2006527724A (ja) | 2006-12-07 |
| ES2293276T3 (es) | 2008-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |