AR040389A1 - Derivados de quinazolina como ligandos del receptor del neuropeptido y (npy) - Google Patents
Derivados de quinazolina como ligandos del receptor del neuropeptido y (npy)Info
- Publication number
- AR040389A1 AR040389A1 ARP030102414A ARP030102414A AR040389A1 AR 040389 A1 AR040389 A1 AR 040389A1 AR P030102414 A ARP030102414 A AR P030102414A AR P030102414 A ARP030102414 A AR P030102414A AR 040389 A1 AR040389 A1 AR 040389A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- amino
- alkoxyalkyl
- hydroxyalkyl
- aryl
- Prior art date
Links
- 102000028517 Neuropeptide receptor Human genes 0.000 title 1
- 108070000018 Neuropeptide receptor Proteins 0.000 title 1
- JWVCLYRUEFBMGU-UHFFFAOYSA-N quinazoline Chemical class N1=CN=CC2=CC=CC=C21 JWVCLYRUEFBMGU-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 125000000623 heterocyclic group Chemical group 0.000 abstract 4
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 3
- 229910052757 nitrogen Inorganic materials 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Chemical group 0.000 abstract 2
- 150000002367 halogens Chemical group 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000004415 heterocyclylalkyl group Chemical group 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 229910052760 oxygen Chemical group 0.000 abstract 2
- 239000001301 oxygen Chemical group 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000030814 Eating disease Diseases 0.000 abstract 1
- 208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000001647 Renal Insufficiency Diseases 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- -1 amino, acetylamino Chemical group 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000006254 cycloalkyl carbonyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005112 cycloalkylalkoxy group Chemical group 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 235000014632 disordered eating Nutrition 0.000 abstract 1
- 125000004994 halo alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000004438 haloalkoxy group Chemical group 0.000 abstract 1
- 125000006517 heterocyclyl carbonyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 201000006370 kidney failure Diseases 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 125000002294 quinazolinyl group Chemical group N1=C(N=CC2=CC=CC=C12)* 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Pueden utilizarse en forma de preparaciones farmacéuticas para el tratamiento o prevención de artritis, enfermedades cardiovasculares, diabetes, insuficiencia renal, trastornos alimenticios y obesidad. Reivindicación 1: Compuestos de fórmula (1) en donde R1 es -O-R4 o -N(R5) (R6); R2 es alquilo o amino; R3 es hidrógeno, alquilo o halógeno; R4 es hidrógeno, alquilo, alcoxialquilo, hidroxialquilo, aralquilo, heterociclilalquilo, cicloalquilalquilo, amino-SO2- o alquilo-SO2-; R5 y R6 son independientemente seleccionados de hidrógeno, alquilo, cicloalquilo, cicloalquilalquilo, alquilcarbonilo, cicloalquilcarbonilo, arilo, aralquilo, arilcarbonilo, alcoxialquilo, hidroxialquilo, heterocíclico, heterociclilalquilo, heterociclilcarbonilo, alquilo-SO2-, arilo-SO2-, heterociclilo-SO2- o amino-SO2- o R5 y R6 juntos con el átomo de N al que están unidos forman un anillo heterocíclico de 5 a 10 miembros que opcionalmente comprende un segundo heteroátomo seleccionado de nitrógeno u oxígeno y, en donde el anillo heterocíclico está opcionalmente sustituido con uno o más sustituyentes independientemente seleccionados de alquilo y alcoxilo; A es un anillo heterocíclico saturado de 5 a 7 miembros que comprende el átomo de nitrógeno que está unido al anillo quinazolina y opcionalmente un segundo heteroátomo que está seleccionado de oxigeno, azufre o nitrógeno y, en donde el anillo A está opcionalmente sustituido con uno o más sustituyentes independientemente seleccionados de halógeno, alquilo, alcoxilo, haloalcoxilo, cicloalquilalcoxilo, hidroxilo, amino, acetilamino, ciano, hidroxialquilo, alcoxialquilo, haloalcoxialquilo y cicloalquilalcoxialquilo
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02014904 | 2002-07-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR040389A1 true AR040389A1 (es) | 2005-03-30 |
Family
ID=30011055
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP030102414A AR040389A1 (es) | 2002-07-05 | 2003-07-03 | Derivados de quinazolina como ligandos del receptor del neuropeptido y (npy) |
Country Status (18)
Country | Link |
---|---|
US (1) | US7205309B2 (es) |
EP (1) | EP1560816A1 (es) |
JP (1) | JP2005535648A (es) |
KR (1) | KR100647932B1 (es) |
CN (1) | CN1665791A (es) |
AR (1) | AR040389A1 (es) |
AU (1) | AU2003281346B2 (es) |
BR (1) | BR0312461A (es) |
CA (1) | CA2489251A1 (es) |
GT (1) | GT200300136A (es) |
MX (1) | MXPA05000131A (es) |
PA (1) | PA8576701A1 (es) |
PE (1) | PE20040646A1 (es) |
PL (1) | PL374817A1 (es) |
RU (2) | RU2296757C2 (es) |
TW (1) | TW200401642A (es) |
UY (1) | UY27883A1 (es) |
WO (1) | WO2004005265A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6900226B2 (en) * | 2000-09-06 | 2005-05-31 | Hoffman-La Roche Inc. | Neuropeptide Y antagonists |
GB0412769D0 (en) | 2004-06-08 | 2004-07-07 | Novartis Ag | Organic compounds |
GB0525068D0 (en) * | 2005-12-08 | 2006-01-18 | Novartis Ag | Organic compounds |
US9107040B2 (en) | 2010-09-29 | 2015-08-11 | Apple Inc. | Systems, methods, and computer readable media for sharing awareness information |
CN103204818B (zh) * | 2013-04-26 | 2015-04-15 | 清华大学 | 一种多取代喹唑啉衍生物的制备方法 |
CN104151255B (zh) * | 2014-07-22 | 2016-07-13 | 清华大学 | 一种多取代喹唑啉亚胺衍生物及其制备方法 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3511836A (en) * | 1967-12-13 | 1970-05-12 | Pfizer & Co C | 2,4,6,7-tetra substituted quinazolines |
US3753981A (en) * | 1970-07-15 | 1973-08-21 | Squibb & Sons Inc | 4-amino-2-styrylquinazoline compounds |
US4035367A (en) | 1974-09-09 | 1977-07-12 | Sandoz, Inc. | Hydroxyalkyl-substituted-amino-quinolines |
CA1247547A (en) | 1983-06-22 | 1988-12-28 | Paul Hadvary | Leucine derivatives |
CA1270837A (en) | 1984-12-21 | 1990-06-26 | Hoffmann-La Roche Limited | Oxetanones |
CA1328881C (en) | 1984-12-21 | 1994-04-26 | Pierre Barbier | Process for the manufacture of oxetanones |
GB8910722D0 (en) * | 1989-05-10 | 1989-06-28 | Smithkline Beckman Intercredit | Compounds |
CA2035972C (en) | 1990-02-23 | 2006-07-11 | Martin Karpf | Process for the preparation of oxetanones |
SK400992A3 (en) * | 1990-11-06 | 1995-08-09 | Pfizer | Quinazolines derivatives for enhancing antitumor activity |
US5274143A (en) | 1991-07-23 | 1993-12-28 | Hoffmann-La Roche Inc. | Process for the preparation of (R)-3-hexyl-5,6-dihydro-4-hydroxy-6-undecyl-2H-pyran-2-one and (R)-5,6-dihydro-6-undecyl-2H-pyran-2,4(3H)-dione |
CA2148260A1 (en) * | 1993-09-10 | 1995-03-16 | Yasutaka Takase | Quinazoline cpompounds |
US5552411A (en) | 1995-05-26 | 1996-09-03 | Warner-Lambert Company | Sulfonylquinolines as central nervous system and cardiovascular agents |
US6004996A (en) | 1997-02-05 | 1999-12-21 | Hoffman-La Roche Inc. | Tetrahydrolipstatin containing compositions |
AU8748798A (en) * | 1997-08-22 | 1999-03-16 | Kyowa Hakko Kogyo Co. Ltd. | 4-aminoquinazoline derivatives |
US6267952B1 (en) | 1998-01-09 | 2001-07-31 | Geltex Pharmaceuticals, Inc. | Lipase inhibiting polymers |
EP1105122B1 (en) | 1998-08-14 | 2005-04-27 | F.Hoffmann-La Roche Ag | Pharmaceutical compositions containing lipase inhibitors |
TR200100472T2 (tr) | 1998-08-14 | 2001-07-23 | F.Hoffmann-La Roche Ag | Lipaz inhibitörleri ile sitozan içeren farmasötik bileşimler |
EA200200424A1 (ru) | 1999-09-30 | 2002-12-26 | Ньюроджен Корпорейшн | Некоторые гетероциклы, замещенные алкилендиамином |
US6900226B2 (en) | 2000-09-06 | 2005-05-31 | Hoffman-La Roche Inc. | Neuropeptide Y antagonists |
DE10064105A1 (de) | 2000-12-21 | 2002-06-27 | Bayer Ag | Neue Substituierte Imidazotriazinone |
AU2002338896B2 (en) | 2001-05-21 | 2006-04-27 | F.Hoffman-La Roche Ag | Quinoline derivatives as ligands for the neuropeptide Y receptor |
-
2003
- 2003-06-27 CN CN038159341A patent/CN1665791A/zh active Pending
- 2003-06-27 AU AU2003281346A patent/AU2003281346B2/en not_active Ceased
- 2003-06-27 WO PCT/EP2003/006868 patent/WO2004005265A1/en active IP Right Grant
- 2003-06-27 BR BR0312461-4A patent/BR0312461A/pt not_active IP Right Cessation
- 2003-06-27 CA CA002489251A patent/CA2489251A1/en not_active Abandoned
- 2003-06-27 EP EP03740372A patent/EP1560816A1/en not_active Withdrawn
- 2003-06-27 MX MXPA05000131A patent/MXPA05000131A/es not_active Application Discontinuation
- 2003-06-27 KR KR1020057000129A patent/KR100647932B1/ko not_active IP Right Cessation
- 2003-06-27 JP JP2004518609A patent/JP2005535648A/ja active Pending
- 2003-06-27 RU RU2005102916/04A patent/RU2296757C2/ru not_active IP Right Cessation
- 2003-06-27 PL PL03374817A patent/PL374817A1/xx not_active Application Discontinuation
- 2003-07-02 PE PE2003000671A patent/PE20040646A1/es not_active Application Discontinuation
- 2003-07-02 PA PA20038576701A patent/PA8576701A1/es unknown
- 2003-07-02 GT GT200300136A patent/GT200300136A/es unknown
- 2003-07-02 TW TW092118070A patent/TW200401642A/zh unknown
- 2003-07-03 AR ARP030102414A patent/AR040389A1/es not_active Application Discontinuation
- 2003-07-03 US US10/613,782 patent/US7205309B2/en not_active Expired - Fee Related
- 2003-07-04 UY UY27883A patent/UY27883A1/es not_active Application Discontinuation
-
2006
- 2006-09-19 RU RU2006133451/04A patent/RU2006133451A/ru not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MXPA05000131A (es) | 2005-04-11 |
UY27883A1 (es) | 2003-12-31 |
RU2296757C2 (ru) | 2007-04-10 |
GT200300136A (es) | 2004-03-15 |
KR20050018947A (ko) | 2005-02-28 |
PL374817A1 (en) | 2005-10-31 |
US7205309B2 (en) | 2007-04-17 |
AU2003281346B2 (en) | 2007-04-05 |
CA2489251A1 (en) | 2004-01-15 |
TW200401642A (en) | 2004-02-01 |
RU2005102916A (ru) | 2006-01-20 |
KR100647932B1 (ko) | 2006-11-23 |
JP2005535648A (ja) | 2005-11-24 |
BR0312461A (pt) | 2005-04-26 |
CN1665791A (zh) | 2005-09-07 |
RU2006133451A (ru) | 2008-03-27 |
US20040029901A1 (en) | 2004-02-12 |
EP1560816A1 (en) | 2005-08-10 |
PE20040646A1 (es) | 2004-09-18 |
WO2004005265A1 (en) | 2004-01-15 |
PA8576701A1 (es) | 2004-03-10 |
AU2003281346A1 (en) | 2004-01-23 |
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